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Goro: New here. Seems like a great community.


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I'm new here and after stumbling across this wonderful site last night, I knew I had to make an account to get all the information I can about tapering off Pristiq. I've been on Pristiq since July of 2017 and have had enough of always feeling tired and the other symptoms that plague me. This seems like the most educated place when it comes to antidepressants and tapering off them and I'm excited to start this journey to a better life without these drugs.


I look forward to getting to know this community.



Edited by Shep
added username to title

Using Pristiq 50mg since July 2017. Not on any other medications.

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  • ChessieCat changed the title to ??? real name enquiry sent: New here. Seems like a great community.
  • Moderator Emeritus

Hi and welcome to SA,


It's really good that you have found SA before getting off your drug.  I'm tapering Pristiq and want you to know that it is possible to taper off this drug.  I started at 100mg and am now down to 4mg.  There are links in my signature which provide more information.


SA recommends tapering by no more than 10% of the current dose followed by a hold of about 4 weeks to allow the brain to adapt to not getting as much of the drug.  Why taper by 10% of my dosage?


When the drug is taken away too quickly we can get withdrawal symptoms:  Dr Joseph Glenmullen's Withdrawal Symptoms


Before you begin tapering what you need to know


Tips for tapering off Pristiq (desvenlafaxine)


To get you started please create your drug signature using the following format.   Keep it simple.  NO diagnoses or symptoms please - thank you.

  • details for last 2 years - dates, ALL drugs, doses
  • summary for older than 2 years - just years and drug/s

Account Settings – Create or Edit a signature



This is your own introductions topic where your can ask questions about your own situation and journal your progress.

Please DO NOT TAG me - thank you

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

  MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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Yes it is my name, sorry about that. Can you change it to 'Goro' please!

Thank you

Using Pristiq 50mg since July 2017. Not on any other medications.

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  • Administrator

Goro, your username has been changed. 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 


My Success Story:  Shep's Success: "Leaving Plato's Cave"


And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance

I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.


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  • Moderator Emeritus

Hi Goro, 


I wanted to welcome you to SA too. You’ve certainly come to the right place if you want to know about tapering. ChessieCat has given you some helpful information.


The main thing to remember is to never taper by more than 10% a month. I can only taper by less than half of that now myself. Also, make sure you hold at least a month inbetween tapers. Listen to your body and if you haven’t stabilised within a month you will need to hold a bit longer. 


Wishing you all the best with your tapering.💚

Been on APs, benzos, ADs and opiates, all for chronic pain. Had severe Akathisia in the past that made me suicidal. Still on Seroquel. 2019:➡️ March10=7.25mg ✔️April17=7.0✔️June5=6.75✔️ July14=6.50✔️Aug28=6.25✔️Oct10=6.20 ✔️ Oct21=6.0✔️Dec16=5.80 ✔️  2020➡️Jan 21=5.60✔️April2=5.40✔️May29=5.20✔️Aug14= 5.0 ✔️Sep29=4.80✔️2021➡️ Jan31=4.60 mg✔️April24=4.40mg✔️Jul17=4.30mg ✔️Aug 28=4.20✔️ Oct 11=4.15✔️Nov1=4.10✔️ Nov21= 4.05✔️ Dec13= 4mg✔️  2022➡️Jan8= 3.95 Jan 31=3.90✔️March2=3.85✔️ April4=3.80✔️June16=3.75✔️July26=3.70✔️Sep2=3.65✔️ Oct21=3.60✔️Dec8=3.55✔️ Jan 26=3.50✔️THIS IS NOT MEDICAL ADVICE, consult a doctor.

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