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Frankgrimes

Frankgrimes: Paxil withdrawal and reinstatment

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Frankgrimes

Hi all -

 

so so I tried to withdraw from 2.5 paxil while increasing my zoloft from 25 to 50.  What a disaster!  The 50 zoloft made me manic so I went back down to 25 but went off the 2.5 paxil in two weeks.  Pure chaos ensued with crazy agitation and insomnia and practically convulsions!

 

then I went down to 12.5 zoloft and after 5 days the crying began.  Reinstated to 25 and feeling the reinstatement effects.  Just wanted to connect with others!

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Altostrata

Welcome, Frankgrimes.

 

Were you trying to switch from Paxil to Zoloft? Why were you doing this and what method were you using?

 

How long have you been taking 25mg Zoloft this round?

 

To help us out, follow these instructions Please put your drug and withdrawal history in your signature You may need to use a computer to do this.

 

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laydefish

Hi @Frankgrimes & Welcome to the group! you came to the right place for great advice & support! Stay Strong!

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Frankgrimes
Posted (edited)

For the past 16 years, I had been on a super random combination - 10mg lexapro and 150 Wellbutrin xl in the morning, 2.5 paxil and 25 Zoloft at night.  For OCD and depression.

 

I started getting breakthrough depression and my Dr. thought the Paxil was doing more harm than good and we should get me off that and increase the Zoloft.  So we did - from 2.5 paxil to 1.25 and 25 zoloft to 50 zoloft.  That night I had the most intense sex and it was unreal.  Like I had never felt before.  Then I fell asleep and woke up early and with energy.  My pupils were huge though - I was high and I felt sexually like a 16 year old.  I told my doc and a day or two later we dropped the Zoloft down to 37.5.  What a productive week of work and gym and dating.  The next week I couldn’t tolerate the increased Zoloft so we went down to 25 zoloft and he said sure go off the Paxil.  

 

So I went from 2.5 paxil to 1.25 to 0 in 2 weeks.  And 25 to 50 to 37.5 to 25 zoloft in 2 weeks.  This all happened between February 18 and March 4.

 

On I believe Wednesday the 6th I called the dr. crying and he said to take 1.25 paxil cuz I was in withdrawal.  Eventually I went back to 2.5 but the hell was done.  I didn’t sleep.  I would wake up screaming.  I paced for hours straight. Advil PM every night.  I went to a urologist and he gave me Levaquin and naproxen and said I had a prostate infection.  I didn’t eat the next 10 days.  I started having pains.  My left left foot went numb.  I had pins and needles.  My left hand was numb.  Pushups hurt my left elbow.  Could the Levaquin have caused my pains?  Was it the withdrawal?  I don’t know.  I think it was the withdrawal because now it comes and goes.  I had electric shocks.  Acupuncture was brutal - so much electricity.

Paxil withdrawal - I need hope!!

 

During this, one time after sex i felt an electric volt up and down my entire left side - the worst pain I have ever felt.  My left hand was numb.  My left foot was numb (my left leg still hurts).  I thought I was floxed from the Levaquin.  It’s still possible - everything hurt - joints, trigger points.  But can be from the withdrawal. 

 

At one point my new doc tried to add deplin.  It got me high.  And then deplin with 12.5 zoloft.  5 days later horrible crying and pain on my left side and withdrawals.  I had the chills again.  Like the flu.  That went away when I restarted the Zoloft.

 

Now 3 months later - I am feeling withdrawal again (or startup effects).  I have switched brands of generics thinking maybe that was the issue that caused the depression and I switched from generic lexapro to brand name.  Since then I’ve been sweating profusely - first night i was waking up with the sweats.  Now I’ll just start sweating like crazy anywhere.  I don’t sleep and I can’t sit still.

 

I have a new doc who wants me to take l-methylfolate and lamictal. He wants me off the SSRIs.  ’m scared.  I can’t take this much more.  My doc said I’ll get better. He said I’m not on what I should be on based on my genetics.  But I feel it’s too late to change now that I went through and felt withdrawal.  Surprisingly I feel pretty good every day from 6 pm - 10 pm.  But then sleep happens.

 

Whenever I think about the stress and permanent damage my leg hurts.  Please give me hope!!

 

Edited by ChessieCat
reduced font/added topic title

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ChessieCat

merged 2 intro topics

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Frankgrimes
Posted (edited)

Tingling/numbness in foot - from name brand lexapro to generic

 

Switched from generic lexapro (17 years) to brand name lexapro and the name brand was way too strong (was on it for 14 days and it made me manic) - 3 days back on generic now and have tingling in my left foot/numbness.  I have had this from withdrawal before but in those cases I reinstated.  

 

Will this go away once my body adjusts to the generic lexapro that I took for 17 years?

 

Edited by ChessieCat
added topic title

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ChessieCat

2 topics merged.

 

Please create your drug signature using the following format.   Keep it simple.  NO diagnoses or symptoms please - thank you.

  • details for last 2 years - dates, ALL drugs, doses
  • summary for older than 2 years - just years and drug/s

Account Settings – Create or Edit a signature

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Altostrata

Hello, Frankgrimes.

 

What is your daily drug schedule? Do your symptoms follow any daily pattern?  Please keep daily notes of times of day you take your drugs, their dosages, and your symptoms. You can post them in this topic with a simple list format with time of day on the left and notation (symptom, drug and dosage) on the right.

 

How does your new psychiatrist propose to get you off the antidepressants? How did he ascertain that l-methylfolate supplementation would be right for you? (Deplin is l-methylfolate.)

 

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Frankgrimes

Hi @Altostrata - He did a genetic assessment and I’m homozygous Mthfr.  He said if this was from scratch he would never have put me on ssri.  It would have been deplin and lamictal if needed.

 

i put my regimen in my signature.

 

When I went off the paxil i also went took Levaquin so my nervous system went through hell!

 

he plans to titrate up the lamictal and when stable taper down the SSRIs very slowly.  The crazy thing is I’m so sensitized now - I never ever had a problem from brand name to generic and today is day 5 brand name to generic so starting to feel the withdrawal in my left foot (that’s where it always is - tingling, numbness - and then crying)

 

does the “withdrawal” eventually stabilize?  Like will my mind (and my body/foot) adjust to the generic lexapro after some time?  I can’t go back to brand name as it made me hypomanic.  Thank you!

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Altostrata

Having a heterozygous MTHFR variation, I've done a lot of reading about it. The most effective way to assure folate absorption with a theoretical MTHFR problem is to eat leafy green veggies. Deplin is not necessary. You seemed to have a bad reaction to it before, some people find even methylfolate supplements to be activating.

 

There are long, elaborate discussions about genetic variations and complex remediations (which I've found to be nonsensical) for those who have  adverse reactions to methyl- supplements, but the fix is: Eat green leafies.

 

If you absolutely must take a methyl- supplement, you can start with a tiny chip off a sublingual tablet and gradually work your way up in dosage.

 

However, the MTHFR issue is probably barking up the wrong tree, and Deplin is an expensive placebo to which you have already reacted badly.

 

Did this psychiatrist tell you to take Lamictal 12.5mg every other day? That's really dumb, half-life is to short to reach steady-state on that schedule. 5mg tablets are available by prescription.

 

When did you start taking Lamictal? (Starting dates for each of the drug dosages in your signature would be helpful.) How do you feel after taking 12.5mg?

 

56 minutes ago, Altostrata said:

What is your daily drug schedule? Do your symptoms follow any daily pattern?  Please keep daily notes of times of day you take your drugs, their dosages, and your symptoms. You can post them in this topic with a simple list format with time of day on the left and notation (symptom, drug and dosage) on the right.

 

 

Thanks for the information in your signature. I need to know TIMES OF DAY for all your drug doses with your symptom pattern, like this:

 

6 a.m. Woke with anxiety
8 a.m. Took 2.5mg Lexapro
10 a.m. Stomach is upset
10:30 a.m. Ate breakfast
11:35 a.m. Got a headache, lasted one hour
12:35 p.m. Ate lunch
4 p.m. Feel a bit better
5 p.m. Took 2.5mg Lexapro
6 p.m. Ate dinner
9:20 p.m. Headache
10:00 p.m. Took 50mg Seroquel
10:20 p.m. Feeling dizzy
10:30 p.m. Fell asleep
2:30 a.m. Woke, took 3mg Ambien (NOT "took 1/2 tablet Ambien")
2:45 a.m. Fell asleep
4:30 a.m. Woke but got back to sleep

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Frankgrimes

Thanks I couldn’t fit this in my signature - I will be more detailed with time of symptoms tomorrow.

 

17 years prior, various brands

 

Am:  10 escitalopram, 150 bupropion xl

Pm:  25 Sertraline, 2.5 paroxetine

 

2/18 

Am: 10 escitalopram, 150 buproprion xl

50 Sertraline, 1.25 paroxetine

 

(Caused mania - didn’t realize it at the time)

 

2/20 

Am:  10 escitalopram, 150 Buproprion xl

Pm:  37.5 Sertraline, 1.25 paroxetine

 

2/27 

Am:  10 escitalopram, 150 buproprion xl

Pm:  25 zoloft, 0 paxil!!

 

Crying started 

 

3/4 

Am:  10 escitalopram, 150 Buproprion xl

25 sertraline, 1.25 paxil (to try to stop withdrawal - but it made me hypomanic as well as I shouldn’t be on SSRIs)

 

Slowly added back paroxetine up to 2.5 over a while

 

3/21 Levaquin 500 mg 10 days, naproxen 10 days

 

4/19 liquid Paxil - 2.5 mg

 

5/5 tried to taper the Sertraline and took 12.5 Sertraline and 15mg deplin as part of my cocktail (horrible crying and foot numbness and electric shocks after 5 days, went back on 25 Sertraline)

 

5/10 switched the Sertraline to aurobindo version - definitely stronger

 

5/30 switched to brand name lexapro - definitely too strong - induced some hypomania but took it for 14 days because I wasn’t aware

 

6/11 25 mg lamictal at night

 

6/12

back to aurobindo escitalopram from brand name

 

6/13 12.5 lamictal at night

 

Current regimen

 

Am:  

150 Buproprion xl (lupin)

10 escitalopram (aurobindo)

Omega 3

Nasonex, eye drops

 

Claritin at 4 pm

 

Pm:

2.5 paxil liquid

25 Sertraline (aurobindo)

Nasonex, eye drops

 

Lamictal taper schedule - 12.5 every other day for first two weeks

 

 

 

 

 

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Frankgrimes

Leafy green vegetables are no good because I can’t break down the folic acid in them.  I have homozygous.  In any case for now I’m not taking it or any other vitamins other than omega 3s.

 

Started lamictal 25 - they have a starter pack where it is 25 every other day first two weeks, then 25 per day for 2 weeks, then 50 every day.

 

i felt side effects immediately - although those could have been from withdrawals  - some spaciness - so he said to be safe do 12.5 every other day for first two weeks, then 12.5 per day for 2 weeks, then 25 every day.

 

My biggest challenge is every time I even adjust an ssri - from brand to generic - or from generic to generic - where one is weaker - my ocd kicks up a little which is okay and my left side gets aggravated.  Whether it is some shocks on my left side or an ache in my lower left leg or tingling/pins and needles in my left foot.  Nothing on my right side.

 

My question is whether these not so little annoyances (aches and pains and numbness) typically go away (in a couple weeks) so that I can continue a taper (go from 10 lexapro to 9 lexapro to 8.1 lexapro, etc).

 

 

 

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Altostrata

TIMES OF DAY, please, like this:

 

6 a.m. Woke with anxiety
8 a.m. Took 2.5mg Lexapro
10 a.m. Stomach is upset
10:30 a.m. Ate breakfast
11:35 a.m. Got a headache, lasted one hour
12:35 p.m. Ate lunch
4 p.m. Feel a bit better
5 p.m. Took 2.5mg Lexapro
6 p.m. Ate dinner
9:20 p.m. Headache
10:00 p.m. Took 50mg Seroquel
10:20 p.m. Feeling dizzy
10:30 p.m. Fell asleep
2:30 a.m. Woke, took 3mg Ambien (NOT "took 1/2 tablet Ambien")
2:45 a.m. Fell asleep
4:30 a.m. Woke but got back to sleep

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Frankgrimes

Day 5 of 10mg generic escitalopram rather than brand name lexapro - day 5 is the day withdrawal usually kicks in for me

 

6/16 evening

 

8:00 pm a bit up and down - crying during a conversation with a friend - 3/10

 

9:00 pm exhausted, can’t stop reading these message boards, fell asleep on couch - numbness and tingling left foot - 5/10

 

9:25 pm woke up from falling asleep - left side burning - left hand pins and needles, almost like I’m on fire with electricity 6/10

 

9:30 pm 

12.5 lamictal

1.25 ml Paxil liquid

25 Sertraline (aurobindo)

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Frankgrimes

Rest of day 5

 

10pm - bed no problem

 

11:30pm I think - intense awakening, electricity type feeling all over, particularly genitals, my left arm and left hand tense up like in a permanent flex/state of defense 5/10

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