Vonnegutjunky Posted May 31, 2019 Share Posted May 31, 2019 Please move if not in the right location. I was contacted about a new med that reduces glutamate that is currently being tested for ALS and other disorders. Would a medication such as this be potentially helpful in wd? Also what would the wd effects of a med like this be? Is it as dangerous as a benzo? More dangerous than an ssri? I am just curious as I am now super interested in learning everything I can about neuroscience. https://www.biohavenpharma.com/science-pipeline/glutamate/troriluzole *Currently at 8.2-8.5 mg of my 10mg pill of Paxil (they actually weigh 12.5mg) january 2023 I began reducing my med again. I was a 9mg weight for years, I went to 8.9 in January, went to 8.6mg in February, and in March 2023 I went down to 8.5-8.2 mg ( my scale varies, so I stick within that .3 range because of that) *No other supplements or vitamins *Taper schedule in the pdf Blank.pdf https://docs.google.com/document/d/1-5vShtJtwAOGA30OxIP87steLmMdFzD29F0fzAPD564 Link to comment Share on other sites More sharing options...
Moderator Emeritus ChessieCat Posted May 31, 2019 Moderator Emeritus Share Posted May 31, 2019 (edited) Did a google search for drug to reduce glutamate and found this Published online 2013 Aug 7.: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3747027/ To me it seems like the chemical imbalance myth once again. Edited May 31, 2019 by ChessieCat * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment Share on other sites More sharing options...
puthappinessfirst Posted May 31, 2019 Share Posted May 31, 2019 I feel like you could try NAC before this, no? Celexa 10mg: 2007 to June 2018, stopped CT No meds: June 2018 to December 2018 PROTRACTED WD-- major depressive episode for 2+ weeks Lexapro 10mg: December 12, 2018 to January 19, 2019, severe adverse reaction Celexa 10mg: January 20, 2019 June 24, 2019: 9mg July 22, 2019: 8.5mg Jan 8, 2020: 8mg Aug 25, 2020: 7.2mg Supplements: Magnesium, Fish Oil Link to comment Share on other sites More sharing options...
Vonnegutjunky Posted May 31, 2019 Author Share Posted May 31, 2019 I would only consider it short term to possibly counteract wd and to help me get off this damn debilitating paxil. And becuse it has low effect on liver function, definitely not as a substitute to treat depression or anything. I am currently very limited in meds I can take due to liver.. I have Benzos to help with wd, but what I'd something like.this were easier and safer to help taper off meds? Including benzos? Just thinking out loud. *Currently at 8.2-8.5 mg of my 10mg pill of Paxil (they actually weigh 12.5mg) january 2023 I began reducing my med again. I was a 9mg weight for years, I went to 8.9 in January, went to 8.6mg in February, and in March 2023 I went down to 8.5-8.2 mg ( my scale varies, so I stick within that .3 range because of that) *No other supplements or vitamins *Taper schedule in the pdf Blank.pdf https://docs.google.com/document/d/1-5vShtJtwAOGA30OxIP87steLmMdFzD29F0fzAPD564 Link to comment Share on other sites More sharing options...
Vonnegutjunky Posted May 31, 2019 Author Share Posted May 31, 2019 12 minutes ago, puthappinessfirst said: I feel like you could try NAC before this, no? I dont even know what that is but I would be willing. *Currently at 8.2-8.5 mg of my 10mg pill of Paxil (they actually weigh 12.5mg) january 2023 I began reducing my med again. I was a 9mg weight for years, I went to 8.9 in January, went to 8.6mg in February, and in March 2023 I went down to 8.5-8.2 mg ( my scale varies, so I stick within that .3 range because of that) *No other supplements or vitamins *Taper schedule in the pdf Blank.pdf https://docs.google.com/document/d/1-5vShtJtwAOGA30OxIP87steLmMdFzD29F0fzAPD564 Link to comment Share on other sites More sharing options...
puthappinessfirst Posted May 31, 2019 Share Posted May 31, 2019 More info: https://www.healthline.com/nutrition/nac-benefits Celexa 10mg: 2007 to June 2018, stopped CT No meds: June 2018 to December 2018 PROTRACTED WD-- major depressive episode for 2+ weeks Lexapro 10mg: December 12, 2018 to January 19, 2019, severe adverse reaction Celexa 10mg: January 20, 2019 June 24, 2019: 9mg July 22, 2019: 8.5mg Jan 8, 2020: 8mg Aug 25, 2020: 7.2mg Supplements: Magnesium, Fish Oil Link to comment Share on other sites More sharing options...
Vonnegutjunky Posted May 31, 2019 Author Share Posted May 31, 2019 26 minutes ago, puthappinessfirst said: Thank you put!!! *Currently at 8.2-8.5 mg of my 10mg pill of Paxil (they actually weigh 12.5mg) january 2023 I began reducing my med again. I was a 9mg weight for years, I went to 8.9 in January, went to 8.6mg in February, and in March 2023 I went down to 8.5-8.2 mg ( my scale varies, so I stick within that .3 range because of that) *No other supplements or vitamins *Taper schedule in the pdf Blank.pdf https://docs.google.com/document/d/1-5vShtJtwAOGA30OxIP87steLmMdFzD29F0fzAPD564 Link to comment Share on other sites More sharing options...
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