Moderator Emeritus Shep Posted July 4, 2019 Moderator Emeritus Share Posted July 4, 2019 Gabapentinoids linked to overdoses and suicide Just out from Mercola today regarding two drugs we commonly see on withdrawal websites. These drugs are gabapentin (Neurontin) and pregabalin (Lyrica). STORY AT-A-GLANCE Gabapentin and pregabalin are used for the treatment of epilepsy and neuropathic pain disorders. Pregabalin, such as Lyrica, is also prescribed for anxiety in Europe and fibromyalgia in the U.S. Recent research links gabapentinoids with a 26% increased risk for suicidal behavior and death from suicide; 24% increased risk for unintentional overdose; 22% increased risk for head or body injury due to an accident; 13% increased risk for traffic violations or accidents and 4% increased risk for violent crime offenses Of the two gabapentinoids, pregabalin — which is the newer of the two — was clearly the worst, accounting for most of these adverse effects, while gabapentin — an older drug — showed “no statistically significant hazards” Research published in 2017 demonstrated that concomitant use of gabapentin and opioids raised the risk of death by 60% over and beyond the risk associated with either drug by itself The suicide rate in the U.S. is now at a 20-year high, having risen 30% between 2000 and 2016 across all age groups. Among Native Americans and Alaska Natives the suicide rate between 1999 and 2017 rose 139% among women and 71% among men Link to comment Share on other sites More sharing options...
Linus Posted July 13, 2019 Share Posted July 13, 2019 On 7/5/2019 at 12:08 AM, Shep said: Gabapentinoids linked to overdoses and suicide Drug makers’ payments to doctors have helped to drive the growing use of gabapentinoids, says a research letter in JAMA Internal Medicine. https://www.bmj.com/content/366/bmj.l4672.full Glad some people got better because of this drug /s Escitalopram 1.05 mg (max of 30 mg, taper from 10 mg to now started september 2016) Klonopin 0.3 mg (one dosage reduction of 25 percent, from 0.4 to 0.3 mg september 2017) Supplements: magnesium malate, fish oil, curcumin, multivitamin, iodine, probiotics, vitamine D along with eating healthy 80 percent of the time, I have no problem whatsoever taking supplements. Link to comment Share on other sites More sharing options...
Recommended Posts