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Offshore: low dose of Remeron / mirtazapine for a long time


Offshore

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Hi all,

 

First off--I am sooooo grateful for this website and forum.  Thank you to whoever thought of creating this site and brought it into reality however many years ago!  

 

I've been on a very low does of Mirtazapine/Remeron--I take an 1/8th of a 7.5mg pill (so about 0.9mg)--for over a year. Prior to that, I was on anywhere from 1.87mg  (quarter tablet) to 3.5mg (half a tablet) for about 4 years. I started taking it when I was going to school and working full-time and I was getting approximately 4 hours a sleep a night.  I am very grateful that it cured my insomnia 5 years ago, but now I'm sleeping fine and life is good and I think that it's time to get off of it.

 

When I tried stopping two weeks ago, I thought that I would be alright--I've read a lot of people's experiences through this site, and I realize that I'm taking an extremely small dose compared to others.  The trouble--I'm assuming--is that I've been taking it for so long that my brain has adjusted and become dependent on this small amount.  Currently, I have no trouble falling asleep and I've been exercising a lot to try and make sure that i'm tired, at the end of the day but I just can't for the life of me stay asleep for longer than 4 hours!  It's been about two weeks of receiving very little sleep and I'm wondering what else I can do to ween myself further off this drug. For my sanity, I think that I'll go back on my little dose for now. 

 

What do you think my next step should be? I'm already using a razor blade and cutting the pill into pretty much as small of a bit as I can. I've looked at getting a scale, but would a .001 g scale show amounts that are less than 1mg? At this point, I would need something that allows me to go from 0.9 mg to 0.7mg. Thank you in advance for any help or advice that you can offer!  

  • 2009--2013: Mirtazapine/Remeron 7.5mg
  • 2013-2015: 3.25mg
  •  2015-2018: 1.625mg 
  • Jan. 2019-March 2019: 1.5mg 
  • April-August 2019: 1.25
  • August-December 2019: 1.0mg
  • January-March 2020: 0.75mg
  • March-June 2020: 0.5mg
  • July-December: 2020 0.25mg
  • Stopped--December 18, 2020
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  • ChessieCat changed the title to Offshore: low dose of Remeron / mirtazapine for a long time
  • Moderator

Welcome to SA, Offshore.

 

The AWS Gemini 20 scale is accurate up to around 4mg pill weight.  Since much of the pill is filler, that would mean the scale would be accurate at much lower doses than 4mg active ingredient.  Go to Brassmonkey's (one of our moderators) thread and take a look at his signature in which he details how low he could go using the scale.  He got down to very tiny doses using the scale before it became inaccurate and he had to "eyeball" the powder.  Very likely you'd be fine with the Gemini scale.

 

Tips for tapering off Remeron 

 

I'm using the Gemini scale but haven't gotten quite down to the doses you're talking about, but it's doing fine at my current 1.9mgai (active ingredient) which for my brand of Lexapro is 19mgpw (pill weight).  Every drug and brand is different and you'd have to weigh your own pills to see what the ratio of active ingredient is to pill weight.  

 

This is your Introduction topic, where you can ask questions, post updates and connect with other members.

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020, 7-week Ativan-Valium crossover + change to one 18.75mg dose, w/1 month hold.

Feb. 9, 2021, begin 10% every 4 weeks taper.  Current dose as of March 22: 14.4mgai.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 16mgai (0.44mgpw).  Aug 2016, discovered SA, holding at 16mg.  Taper is 78% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg.


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

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  • 1 year later...

Hello everyone,

 

I'm wondering if anyone has any experience with getting to what seems like a micro-dose and STILL not be able to come off of their medication without withdrawal?  I can't tell sometimes if this is all in my head or if am genuinely experiencing withdrawal...

 

Here's the backstory:

I've taken Mirtazapine/Remeron consistently for about ten years, but never in any doses larger that 7.5mg.  Starting about two years ago (and with the help of this site!), I started my taper by using a compounding pharmacy and went all the way down to 0.25mg.  I've been on this dose for approximately the last 4 months and I assumed (and hoped) that I would be able to stop from this dose.  Today (I'm writing this at 3:35am) is my tenth night completely off Remeron and while I can fall asleep, I can't usually stay asleep and I've been getting anywhere from 2.5 -4 hours of sleep per night.  It FEELS like my nervous system is just "off," but how can that be possible, given the small dose I've been taking?  

 

I will admit--I'm pretty demoralized right now and I'm not sure what my next steps should be. From what I've read, it seems like I'm on a much lower dose than other people who have quit, and yet it is STILL so difficult!   Should I go back on Mirtazapine?  Taper to 0.20mg? Maybe try magnesium and fish oil to calm my nervous system? Does anyone else have experience with tapering to what seems to be a micro-dose and not being able to quit?     

 

   

  • 2009--2013: Mirtazapine/Remeron 7.5mg
  • 2013-2015: 3.25mg
  •  2015-2018: 1.625mg 
  • Jan. 2019-March 2019: 1.5mg 
  • April-August 2019: 1.25
  • August-December 2019: 1.0mg
  • January-March 2020: 0.75mg
  • March-June 2020: 0.5mg
  • July-December: 2020 0.25mg
  • Stopped--December 18, 2020
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  • Moderator

Hi @Offshore,

 

Sorry this happened to you. It's actually common to get much lower than 0.25mg of Mirtazapine before jumping. If you look in the Success Stories section, you'll see that some people actually got as low as 0.025mg, or 1/10th of your last dose. Even with low dosages like 0.25mg, the drug still has some significant activity at the receptors. I think if you are sleeping 2-4 hours a night, that is a sign that you should probably try to reinstate. Let me know if you need help with that, but if you are doing it yourself you should probably start with a lower dose than your last dose (maybe start with 25% or so). Sometimes acute withdrawal can sensitize the nervous system and make an adverse reaction more likely at higher doses. 

 

If you'd like some personalized help, please summarize your drug history as instructed here.

 

You seem like you're already familiar with the site, but here is a list of coping techniques if you need them.

 

Hope we are able to turn things around for you!

Edited by DataGuy

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

Link to post

Thank you Dataguy!  This is very helpful.  I appreciate all of the links that you put there--I love this site and the way that it's designed but it's also nice to have these helpful links here that are immediately applicable to my situation.  I was looking primarily through the general  and tapering topics on Mirtazapine, but I will go and check out some of the success stories now.  Thank you for taking the time to respond; I appreciate it!  Happy Holidays!

  • 2009--2013: Mirtazapine/Remeron 7.5mg
  • 2013-2015: 3.25mg
  •  2015-2018: 1.625mg 
  • Jan. 2019-March 2019: 1.5mg 
  • April-August 2019: 1.25
  • August-December 2019: 1.0mg
  • January-March 2020: 0.75mg
  • March-June 2020: 0.5mg
  • July-December: 2020 0.25mg
  • Stopped--December 18, 2020
Link to post
  • Moderator

Happy holidays, @Offshore. Let us know if you have any more questions or run into any problems. Mirtazapine is a bit of a doozy and tapering is a surprisingly involved and complicated process. Just when we think we know enough, we realize there are very basic practical questions that we don't know the answers to. I'm glad you are close to getting off.

 

You might find this thread on tips for sleep problems useful, as well. 

 

Good luck : )

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

Link to post
  • Administrator

@OffshorePlease note I merged your two introduction threads together. This keeps all of your information in one place. Please continue to use this thread to document your taper and to ask questions. 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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Thank you @Shep and @DataGuy!  I greatly appreciate your work.  

  • 2009--2013: Mirtazapine/Remeron 7.5mg
  • 2013-2015: 3.25mg
  •  2015-2018: 1.625mg 
  • Jan. 2019-March 2019: 1.5mg 
  • April-August 2019: 1.25
  • August-December 2019: 1.0mg
  • January-March 2020: 0.75mg
  • March-June 2020: 0.5mg
  • July-December: 2020 0.25mg
  • Stopped--December 18, 2020
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