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Arthur: looking for insight


Arthur

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I'm sorry you broke your toe, Arthur. That does sound very painful. 

 

Please see:

 

Painkillers in withdrawal: aspirin, ibuprofen, paracetamol, acetaminophen, naproxen, codeine

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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I cannot believe that this was his advice . It is so negligent!

My body feels like it vibrating all the time.. my sleep the past 2 weeks has declined again and I have held all my med drops.. I cannot nap... the only thing that has been helping me survive was moving.. my wife wanted me to take a benzo last night and I just refuse to take those.. I was in and out of sleep all night.. I can handle no stress at all.. when I try and sleep in the day my body I’ll kick out and have a violent body shake.. I have damage to my Trigeminal nerve and my face hurts constantly.. that’s what got me on the meds in the first place.. I came off them basically cold turkey... I am scared as the structure that has helped me survive to this point has now been severely disrupted..

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • 1 month later...

Hello. It’s been a while since I’ve checked in. My sleep has deteriorated once again. I have held my meds and have not increased or decreased. I am feeling very lost and very depressed and I think that I need to taper. I do not know whether I am still suffering the effects of my Lexapro cold turkey that I did eight months ago plus I’m having trouble navigating The way the current meds are affecting me. I cannot stop crying all the time morning for the life that I’ve lost. I feel such a deep pain in my soul it is overwhelming I will update my signature now and keep daily journals of my symptoms and patterns religiously so I can hopefully Begin to make sense of this. Any help would be great.

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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I need help in my understanding of how to do my liquid self prepared measurements as well.. I have much pain in my face and my sleep has been so off that it is hard to me to absorb and calculate things.. I notice with the ami that it does not dissolve completely in the water solution 

 

 

 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Administrator
16 hours ago, Arthur said:

I need help in my understanding of how to do my liquid self prepared measurements as well.. I have much pain in my face and my sleep has been so off that it is hard to me to absorb and calculate things.. I notice with the ami that it does not dissolve completely in the water solution 

 

 

Arthur, I'm not as familiar with amitriptyline as some of the other mods, so I've asked them to help out on your thread. 

 

In the meantime, please let us know more about where you're at in your taper. Please post the time(s) of day you take your drugs and the doses. Also include your supplements. 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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Apri 23... to 24

830 pm.. 40 mg trileptal 

1045 7.5 mg Amitriptyline 

headache and nerve pain in face and jaw

12 pm 500 mg Tylenol 

homeopathic med coffea cruda

1230 sleep till 5

able to go in and out of sleep till 730

830 am 40 mg trileptal 

all day anxious crying

severe tmj and nerve damage from dental operations 24/7....except when sleeping..

Supplements are 400 mg mag in lights form drank thru out the day and 100 mg spirullina 

2000 mg lions mane mushrooms

i have also taken .5 klonopin twice in the past 2 months last time was 3 weeks ago

 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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Trying to find which drug to taper first.. I’m thinking the Amitriptyline as that can be more activating.. with the trileptal acting as the brake..

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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April 24 to 25

830 pm 40 mg trileptal 

1045 7.5 mg Amitriptyline 1.5 mg melatonin 

up on phone till 1115 .awaken at 1220

sleep in and out till 500 am

Lay in bed and rest till 8 am

feel bad

take 40mg trileptal 

30 min later muscle twitching in thighs

lay on couch till 1030

eat breakfast with family 

very sad at life and situation

lifeless feeling 

830 40 mg trileptal 

1045 7.5 mg Amitriptyline  1.5 mg melatonin 

 broken sleep  12 to 530

memory suffering from lack of sleep 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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I just screwed up and took my trileptal dose twice

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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It’s was on accident.. I got my med cups mixed up

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Administrator

It may take a few days for the extra trileptal dose to work it's way out, but you'll be okay. 

 

Just a few thoughts on your drug and symptoms journal. 

 

On 4/24/2020 at 11:25 AM, Arthur said:

2000 mg lions mane mushrooms

 

Please add when you take this supplement in your drug and symptoms journal. Do you take it in the morning or at night? 

 

Please also see this post in the thread on this supplement.

 

Mushroom Supplements: Lion's Mane, Reishi, Shiitake, AHCC

 

When did you start taking it?

 

19 hours ago, Arthur said:

sleep in and out till 500 am

Lay in bed and rest till 8 am

feel bad

take 40mg trileptal 

30 min later muscle twitching in thighs

lay on couch till 1030

eat breakfast with family 

 

You may want eat breakfast when you first wake up instead of waiting several hours. Some of your symptoms may be from low blood sugar from not eating since the day before. Symptoms of low blood sugar include fatigue, anxiety, low mood, and many other symptoms that mimic withdrawal. 

 

Having a healthy breakfast high in protein and low in sugar can help you start the day strong. 

 

 

19 hours ago, Arthur said:

1045 7.5 mg Amitriptyline  1.5 mg melatonin 

 broken sleep  12 to 530

 

The melatonin dose may be too high, especially taking it along with a sedating drug like amitriplyine.

 

You may want to reduce your melatonin to 1 mg and see if you sleep better. Please see:

 

Melatonin for sleep

 

Please post your thoughts on this. 

Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 

 

My Success Story:  Shep's Success: "Leaving Plato's Cave"

 

And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

 

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Ok... same thing as last night.. my sleep may have been alittle better.. I am wondering if the trileptal I am taking is speeding up the breakdown of the Amitriptyline I am taking as they compete with the same liver enzymes.. and info would be greatly appreciated 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Administrator
23 hours ago, Arthur said:

Ok... same thing as last night.. my sleep may have been alittle better.. I am wondering if the trileptal I am taking is speeding up the breakdown of the Amitriptyline I am taking as they compete with the same liver enzymes.. and info would be greatly appreciated 

 

Arthur, what liver enzyme interactions do these 2 drugs have?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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The p450 system.. I also think I could be getting interdose withdrawal as the half life is 9hrs

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Administrator

Please post the details of the P450 interactions and the half-life information here, so we don't have to do the same work looking them up. Thanks.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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2008-02_042-03.jpg

Oxcarbazepine (Trileptal) is a related antiepileptic drug. It too is metabolized by CYP3A4 and is an enzyme inducer; however, fewer data are available regarding its effects on other drugs. Pending further studies, it would be prudent to assume that oxcarbazepine has a similar interaction profile as carbamazepine. One comparative study on the induction effects of the 2 drugs found that carbamazepine was a more potent inducer of CYP3A4 than oxcarbazepine.2

Elimination half-lives in healthy volunteers are 1-5 hours for oxcarbazepine and 7-20 hours for MHD. Longer and shorter elimination half-lives have been reported in elderly volunteers and children, respectively. Mild to moderate hepatic impairment does not appear to affect MHD pharmacokinetics

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

Link to post

Amitriptyline: (Moderate) Use amitriptyline with caution in patients with a history of seizures; amitriptyline may lower the seizure threshold and thus potentially interfere with the ability of antiepileptics to control seizures. In addition, concomitant use of amitriptyline and oxcarbazepine may result in additive CNS depression. Oxcarbazepine, a CYP2C19 inhibitor, can increase plasma concentrations of amitriptyline, a substrate of CYP2C19. 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • 5 weeks later...
  • Administrator
Altostrata

Arthur, how are you doing?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 2 months later...

I’m not doing to hot.. my trigeminal pain is thru the roof.. I know I haven’t been on heat in awhile but I always check in.. part of my problem is not withdrawal related but damaged nerves in my face that withdrawal had complicated.. I made a huge mistake in smoking Alittle thc 9 days ago and that has sent me spiraling.. 1 to 3 hrs sleep the past 3 days. Then tried to go up to 10mg on the ami for a day and that made me feel terrible . never again.. my body cannot handle any changes in this sensitive state..  I’m just holding on all changes waiting for my central nervous system to calm.. then I must taper the ami next as that is causing problems with shaking.. I never knew he’ll could live on earth like this.. I miss life and my family horribly.. I tried to increase my melatonin and it actually made my sleep worse.. maybe I am missing is off with how the liquid ami I’m making is dissolving.. thought would help..

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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Thoughts on this.. I wake up shaking and I think I’m having some adverse reactions to the ami.... 

 

oxcarbazepine oral and amitriptyline oral

oxcarbazepine oral will increase the level or effect of amitriptyline oral by altering drug metabolism.    
 

 I take my trileptal at 830 and my ami at 1030 

 

what I’m asking is should I taper the ami first at a slower rate since the trileptal seems to increase the plasma level or vise versa.. thank you

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Moderator Emeritus
On 8/16/2020 at 2:27 AM, Arthur said:

I made a huge mistake in smoking Alittle thc 9 days ago and that has sent me spiraling

 

I've just noticed the above in your post.  Did  the shaking start after the thc?

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

Plodding along inch by inch:  12" = 1',  3' =  36 " or 1 yard,  1760 yards  = 63,360" or 1 mile

Current from 17 Apr 2021:  Pristiq 0.2665mg  now holding each dose for 3 weeks

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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  • Moderator Emeritus

From Medscape Drug Interaction Checker

  • marijuana + amitriptyline

    marijuana will increase the level or effect of amitriptyline by affecting hepatic/intestinal enzyme CYP3A4 metabolism.

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

Plodding along inch by inch:  12" = 1',  3' =  36 " or 1 yard,  1760 yards  = 63,360" or 1 mile

Current from 17 Apr 2021:  Pristiq 0.2665mg  now holding each dose for 3 weeks

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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  • Administrator

Yes, you will have to let your nervous system settle down from any drug experiments.

 

On 4/30/2020 at 4:43 PM, Arthur said:

Amitriptyline: (Moderate) Use amitriptyline with caution in patients with a history of seizures; amitriptyline may lower the seizure threshold and thus potentially interfere with the ability of antiepileptics to control seizures. In addition, concomitant use of amitriptyline and oxcarbazepine may result in additive CNS depression. Oxcarbazepine, a CYP2C19 inhibitor, can increase plasma concentrations of amitriptyline, a substrate of CYP2C19. 

 

15 hours ago, Arthur said:

Thoughts on this.. I wake up shaking and I think I’m having some adverse reactions to the ami.... 

 

oxcarbazepine oral and amitriptyline oral

oxcarbazepine oral will increase the level or effect of amitriptyline oral by altering drug metabolism.    
 

 I take my trileptal at 830 and my ami at 1030 

 

what I’m asking is should I taper the ami first at a slower rate since the trileptal seems to increase the plasma level or vise versa.. thank you

 

The interaction between the 2 drugs reaches an equilibrium in a few weeks after you take them together.

 

Is that 8:30 and 10:30 a.m. or p.m.? Do either of these drugs make you sleepy?

 

Quote

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid

 

When did you make this change in amitriptyline and why? Does it coincide with the beginning of some of your symptoms?

 

 

 

 

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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No it didn’t start after the thc.. this has been ongoing

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

Link to post

It’s in 830 pm for the trileptal and 1030 pm for the ami.. then I take and 830 am dosage of the trileptal 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

Link to post

I went back down to 7.5 mg after only taking the ami at 10 mg for one day.. that was one week ago.. it made me feel even more terrible at 10mg.. since I have a chronic pain problem and my fight or flight reflex is on high alert could it be that the Noradrenergic properties to the ami are causing it to be worse..?? The ami actually makes my heart race alittle sometimes.... I’ve been stuck like this for months.. I’m dissolving the 30 mg of ami in 160 mg of water and taking 40 mg of solution at 1030.. I’m at a loss to this as the night before in slept 7 hrs and now last night I slept roughly 3.. the sleep deprivation is having a significant impact on my thought processes..

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Administrator

We don't work with neurotransmitters, we go by your symptoms. If a drug makes you feel worse, it doesn't matter what neurotransmitters are doing. If your nervous system is in an uproar from drug changes, the effect of anything cannot be predicted.

 

If you get high heart rate after taking a drug, the drug is too stimulating for you, regardless of purported neurotransmitter effects. This can also occur because of a drug-drug interaction, or a paradoxical effect. Please put ALL your drugs in the Drug Interactions Checker https://www.drugs.com/drug_interactions.php
and copy and paste the results or a link to them in this topic.

 

This is not the only potential interaction:

 

On 4/30/2020 at 4:36 PM, Arthur said:
2008-02_042-03.jpg

Oxcarbazepine (Trileptal) is a related antiepileptic drug. It too is metabolized by CYP3A4 and is an enzyme inducer; however, fewer data are available regarding its effects on other drugs. Pending further studies, it would be prudent to assume that oxcarbazepine has a similar interaction profile as carbamazepine. One comparative study on the induction effects of the 2 drugs found that carbamazepine was a more potent inducer of CYP3A4 than oxcarbazepine.2

Elimination half-lives in healthy volunteers are 1-5 hours for oxcarbazepine and 7-20 hours for MHD. Longer and shorter elimination half-lives have been reported in elderly volunteers and children, respectively. Mild to moderate hepatic impairment does not appear to affect MHD pharmacokinetics

 

What is your current daily drug schedule, with dosages for each drug? What is your sleep pattern? Please keep daily notes of times of day you take your drugs, their dosages, and your symptoms throughout the day. Post 24 hours of notes at a time in this topic, in a simple list format with time of day on the left and notation (symptom or drug and dosage) on the right.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Ok. I will start tonight.. thank you

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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Sunday August 23

wake up 330 am.. I’m and out of sleep till 630. 
vivid dreams and visions when I close my eyes

 830 am 40 mg trileptal 

inner body vibration 

10 am lessens

work and try to stay busy to distract 
11 am . Breakfast two eggs and 200mg spirullina

work don’t feel to horribly bad and I keep moving to distract

830 pm 40 mg trileptal 

1030 pm 7.5 mg ami 1.5 mg melatonin extrended release 

sleep 1145 to 510 

lay in a semi state of in and out consciousness till 830 am

 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Administrator

Do you feel better or worse after you take Trileptal in the morning?

 

Why are you taking Trileptal?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Nerve pain in face.. trigeminal neuropathy..I feel alittle better after taking it..both drugs I take for nerve pain 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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Aug 25 tues

12 to 530 sleep 

530 wake up slightly nauseous 

530 to 730 in and out of semi consciousness.. 

830 40 mg trileptal 

10 am feel slightly better

1030 am extreme depression 

1030 till 430 work exhausted 

eyes won’t focus well.. 

530 home.. face hurts constantly abnormal pins and needles all over 

830pm.. trileptal 40 mg

feel slightly better by 930

1030 pm ami 7.5 and 1.5 melatonin 

1130 pm sleep

330am wake

430 am sleep till 7 am

 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • 2 months later...

So I need help with how to taper this Amitriptyline 7.5 mg first.. I have been on it about 10 months and I am developing some itching on my palms from time to time and some rashes of sorts.. I am wondering if the solution I’m makes in water to get 7.5 mg is dissolving properly.. the dry mouth I am encountering as a result of this is beyond horrible.. I need to get off this drug as it is effecting me adversely.. 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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  • Moderator Emeritus

Tips for tapering off amitriptyline

 

Post #1 of the above topic explains in detail how to make a liquid.

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

Plodding along inch by inch:  12" = 1',  3' =  36 " or 1 yard,  1760 yards  = 63,360" or 1 mile

Current from 17 Apr 2021:  Pristiq 0.2665mg  now holding each dose for 3 weeks

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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  • 4 months later...

So I haven’t checked in for awhile.. I had a series of mistakes.. I have seen an oral facial pain specialist and my trigeminal nerves are damaged.. out of desperation I took 3 doses of Lyrica and at the third one woke with nausea and basically shook for three hrs before passing out 3 days ago.. I stoped the medication immediately.. then last night I forgot to take my dose of liquid amitryptiline so I worry of even further destabilization.. I have a contacted an interventional pain practice that deals with oral facial pain sense medication is no longer on the table and may have to have a serious surgery.. my mind definitely feels better not taking the Lyrica as I felt extremely dumbed down and my sleep wasn’t that particularly altered last night.. I am at 6.75 mg ami as of now and am considering a very long hold to stabilize.. I wake at 430 every morning and with constant face pain with my jaw constantly dislocating.. I have just purchased a mouth guard and my hope for things is very little.. hope everyone is doing well 

Arthur 

Chronic cannabis use thru out..

2013 to 2016 lexipro 10mg .3 day taper.. sept 2016.january 2017 reinstated lexipro 10 to 20 mg..900 mg gabapentine.feb 2018 .5 ativan

 taper 10 mg lexipro  March 2019 

o mg lexipro aug 2019.. quit cannabis horrible insomnia. trail 2 days of Amitriptyline 10 mg and 2 day Prozac 20 mg  trilpetal 50 mg x2 daily.. 11/16 cut 45 mg x2.. burning left side of face constant from nerve damage from teeth extraction or SSRI withdrawal??

december 3 2019. 5mg Amitriptyline January 3 current meds And supplements 

amitriptyline 7.5 mg trileptal 40mg 1.5 mg melatonin  400 mg magnesium remag liguid. Currently at 6.8 mg amitriptyline and 36 mg trileptal

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Hello @Arthur !! Good to hear from you ! I will tell you when I miss a dose of a ssri I feel small effects like maybe dreaming, getting up early, sleeping too much or concentrate problems for a few days. Now if I am tapering and miss a dose that intensifies everything for a little longer. That’s just me. I usually don’t worry too much missing one day over 6 months time.
 

I think holding dosage for a while is a good idea! Remember to hold during major life changes especially for surgery . Wishing you good health and healing and speedy recovery with your upcoming surgery !

09/2000 paxil 20mgs, 06/2006 stopped Paxil crashed, 10/2006 progressed back up to Paxil 20mgs, 2012 -2013 Paxil 12 month taper crashed, 09/2013 Zoloft 50 - 100, 2015-2016 Zoloft taper crash, 2016 cymbalta, 01/2017   lamictal , 05/2017 Prozac 20 mgs, 06/2017 Prozac 40mgs, 02/2018 Prozac 20 mgs, 05/2018 Prozac 30 mgs, 11/2018 lexapro 10 mgs, 01/2019 lexapro 15 mgs, 12/07/2019 lexapro 13.75 mgs ,01/04/2020 lexapro 12.5 mgs, 02/08/2020 lexapro 11.25 mgs, 03/07/2020 lexapro 10 mgs, 07/25/2020 7.5mg pill&2.5ml liquid, 08/04/2020 5mg pill&5ml liquid, 08/17/2020 2.5mg pill 7.5 ml liquid, 08/24/2020 10 ml liquid lexapro, 09/05/2020 9 ml liquid lexapro, 10/05/2020 8.5 ml liquid lexapro,10/12/2020 9 ml, 04/17/2021 8.78 ml, 04/24/2021 8.56 ml, 05/02/2021 8.34 ml, 

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