The large number of adverse health effects vs the limited symptom-reducing effects of antidepressants suggests they could generally do more harm than good.   Frontiers in Psychology Vol. 3 2012 #00117 DOI=10.3389/fpsyg.2012.00117 ISSN=1664-1078   Primum non nocere: an evolutionary analysis of whether antidepressants do more harm than good Paul W. Andrews1,2*, J. Anderson Thomson Jr.3,4, Ananda Amstadter2 and Michael C. Neale2   1 Department of Psychology, Neuroscience and Behaviour,