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Stahl, 2001 Natural Estrogen as an Antidepressant for Women


Barbarannamated
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Astounding, indeed! The Archives of General Psychiatry article is from 2001. Dr. Stahl's name is almost hidden, just listed as 'Stahl'. I'd like to get Lori Altschuler Expert Consensus Guidelines on Treatment of Depression from Postgraduate Medicine, March 2001, referenced.

 

Natural Estrogen as an Antidepressant for Women

Stephen M. Stahl, MD, PhD

Brainstorms

http://www.psychiatrist.com/pcc/brainstorm/br6206.htm

Related article:

Sex and Psychopharmacology

Is Natural Estrogen a Psychotropic in Women?

Archives of General Psychiatry, 2001: 58

Stahl

http://archpsyc.ama-assn.org/cgi/content/extract/58/6/537

 

Clinicians have observed, anecdotally and in open studies of small numbers of patients,that estrogen apparently exerts antidepressant actions as a monotherapy when administered to some women who have MDD both in the postpartum period and during perimenopause.

It is somewhat astounding that controlled clinical trials of estrogen for depressed women across their life cycle are only now being published, since not only do women of child-bearing potential have the highest rates of depression, but also women on the whole consume over 70% of antidepressants.

 

Two recently published,well-designed studies now suggest that 17 beta-estradiol may indeed be an antidepressant for women with depression during perimenopause, including women with MDD. In fact, estradiol treatment was associated with a robust treatment effect, including complete remission in the majority of patients studied.

Edited by Altostrata
formatted title to conform to Journals listings

Pristiq tapered over 8 months ending Spring 2011 after 18 years of polydrugging that began w/Zoloft for fatigue/general malaise (not mood). CURRENT: 1mg Klonopin qhs (SSRI bruxism), 75mg trazodone qhs, various hormonesLitigation for 11 years for Work-related injury, settled 2004. Involuntary medical retirement in 2001 (age 39). 2012 - brain MRI showing diffuse, chronic cerebrovascular damage/demyelination possibly vasculitis/cerebritis. Dx w/autoimmune polyendocrine failure.<p>2013 - Dx w/CNS Sjogren's Lupus (FANA antibodies first appeared in 1997 but missed by doc).

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Hmmm, since when is Stephen Stahl, famous pharma consultant, an expert on estrogen for women?

 

I'm wondering in whose service he did this flogging more than 10 years ago.

 

It's very well known that estrogen supplementation is antidepressant for women.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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My thoughts exactly, Alto.

This was just before Women's Health Initiative halted (2002).

Pristiq tapered over 8 months ending Spring 2011 after 18 years of polydrugging that began w/Zoloft for fatigue/general malaise (not mood). CURRENT: 1mg Klonopin qhs (SSRI bruxism), 75mg trazodone qhs, various hormonesLitigation for 11 years for Work-related injury, settled 2004. Involuntary medical retirement in 2001 (age 39). 2012 - brain MRI showing diffuse, chronic cerebrovascular damage/demyelination possibly vasculitis/cerebritis. Dx w/autoimmune polyendocrine failure.<p>2013 - Dx w/CNS Sjogren's Lupus (FANA antibodies first appeared in 1997 but missed by doc).

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  • 3 months later...

Pristiq tapered over 8 months ending Spring 2011 after 18 years of polydrugging that began w/Zoloft for fatigue/general malaise (not mood). CURRENT: 1mg Klonopin qhs (SSRI bruxism), 75mg trazodone qhs, various hormonesLitigation for 11 years for Work-related injury, settled 2004. Involuntary medical retirement in 2001 (age 39). 2012 - brain MRI showing diffuse, chronic cerebrovascular damage/demyelination possibly vasculitis/cerebritis. Dx w/autoimmune polyendocrine failure.<p>2013 - Dx w/CNS Sjogren's Lupus (FANA antibodies first appeared in 1997 but missed by doc).

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