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tish

tish: buspirone and Depakote

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tish

Is bupirone an activator or sedative? trying to taper off , but it's causing me real shaking,


2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

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Gridley

Welcome to SA, tish.  Sorry for the delay in responding.

 

Buspirone is a sedative.  The shaking is very likely caused by your tapering too fast, causing you to suffer from withdrawal.  Shaking is a common withdrawal symptom.

 

 

 

 How fast are you tapering?  How long have you been tapering?  What was your original dose and what is your current dose?  Please put this information in a drug signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.

We recommend tapering Buspirone by no more than 10% of current dose every four weeks.

 

Why taper by 10% of my dosage?

 

The following link is specifically about tapering Buspirone.

 

Tips for tapering off busipirone (Buspar)

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

 

 

Please research all supplements first and only add in one at a time and at a low dose in case you do experience problems.
 
This is your Introduction topic, where you can ask questions and connect with other members.  Again, welcome.

Gridley Introduction

 

Lexapro 20 mg since 2004.  Began taper using Brassmonkey slide Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Current from Aug 13, 2020 at 0.1mg

Taper is 99.5% complete.

 

Lorazepam 1 mg 1986-1991 CT, resumed a few months later. CT 2000.  1 mg 2011-2016.  Sept, 2016 increased to 0.5 X 3 in split dose. Sept. 2019 increased to 0.625 X 3 after crossover to new brand

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 15mg.  Aug 2016, discovered SA, updosed to 25mg and holding.  Taper is 66% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, melatonin .33mg


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

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tish

I'm on 500mg of depakote [2x250mg] and needing advice to reduce as my shaking hands are causing me problems.My Neurologist thinks that the medication could be the problem.

Unfortunately in the UK liquid seems to be unavailable and crushing them is not recommended.So I'm at a loss as to how to do this.

I was put on 500mg depakote [2006]14 years ago after a Bi polar 2 diagnosis I reduced it after around 5years to 250mg, but then it was increased to 500mg in feb 2019 due to personal external pressures.

I am also taking Trazadone 300mg from 2006 - 2011,  reduced to150mg from 2011 to Jan 2019 then increased to 200mg.

zopiclone 7mg from 2006  reduced to 3.75mg  approx 2008

propranolol 10mg as & when to help with shaking from april 2019.

Buspirone 5mg since march 2019 shaving approx 1mg off for last 5 weeks. feeling terrible. 

Thank you to anyone who has experience of depakote withdrawal.x


2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

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ChessieCat

Hi tish and welcome to SA,

 

To get you started please create your drug signature.  Please include ALL drugs.

 

Instructions:  Withdrawal History Signature


Account Settings – Create or Edit a signature

 

Also, please put ALL the drugs your are CURRENTLY taking in the Drug.com Interactions Checker.  Either copy and paste the results here in a post OR copy and paste the URL for the report.  Thank you.

 

I have asked the other mods for their assistance.

 

This is your own introduction topic where you can ask questions and journal your progress.

 

Edited by ChessieCat

Being very patient.  I'll get there - slowly.  ETA mid 2021

ADs:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft/sertraline; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after)

Pristiq:  50mg 2012, 100mg beg 2013 (mild Serotonin Toxicity)

Began tapering Oct 2015  Current from 12 Sept 2020:  Pristiq 0.625 mg (compounded)

My tapering program

My Intro (goes to my tapering graph)

My website - includes my brief history + links to videos & information on the web

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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tish

Hi Chessiecat, thank you for your reply.

I listed all my meds on the intro page, with doseage and dates, sorry but not sure what else I need to do.


2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

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tish

 Hello everyone,

Looking for help/ experience of tapering off Depakote ER.

Many thanks.


2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

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Gridley

Welcome from me too, tish.

 

We recommend tapering by no more than 10% of your current dose every four weeks.

 

Why taper by 10% of my dosage?

 

This link is specifically about tapering Depakote.  At the end of the first post are specific instructions about how to taper 500mg ER.   

 

 

Tips for tapering off sodium valproate and valproic acid (divalproex sodium, Depakote, Depakene)

 

Please also complete the drug interaction check as requested by ChessieCat and paste it here in your thread according to her instructions.  The link is in her previous post to you.

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

Magnesium, nature's calcium channel blocker 

 

Omega-3 fatty acids (fish oil) 

 

Add in one at a time and at a low dose in case you do experience problems.

 

We recommend tapering only one drug at a time.  Your buspirone taper is much faster than the 10% of current dose every four weeks than we recommend.

I suggest you hold where you are on the buspirone if you're going to taper Depakote.  Please put the dates and rate of taper of your buspirone taper in your signature using this link.  

 

Account Settings – Create or Edit a signature.

 

This is your Introduction thread.  Only one Introduction thread per member, so please don't start any new Introduction threads.  All your questions and posts should go here in this thread.

 

Edited by ChessieCat

Gridley Introduction

 

Lexapro 20 mg since 2004.  Began taper using Brassmonkey slide Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Current from Aug 13, 2020 at 0.1mg

Taper is 99.5% complete.

 

Lorazepam 1 mg 1986-1991 CT, resumed a few months later. CT 2000.  1 mg 2011-2016.  Sept, 2016 increased to 0.5 X 3 in split dose. Sept. 2019 increased to 0.625 X 3 after crossover to new brand

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 15mg.  Aug 2016, discovered SA, updosed to 25mg and holding.  Taper is 66% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, melatonin .33mg


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

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tish

hi and thank you Gridley, I'm holding on the Buspirone and using a syringe to liquid taper a more accurate 0.5mg now.

 

My struggle is to obtain a liquid dose of the depakote as it isn't available in the uk & the smallest tablet is 250mg.

 

Edited by ChessieCat
unbolded

2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

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Altostrata

Hello, tish.

 

Before doing anything else, read

 

Can you get Depakote sprinkles? They're probably the most convenient way to taper.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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tish

Thank you, Not sure on the sprinkles as they are direct release[DR] and I am on  extended release {ER]at the moment.

concerned if the 2 can be mixed.


2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

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tish

Until I can start my Depakote taper, can you help me with the Buspirone please.

I'm holding at 4.5mg as recommend,I'm crushing the 5mg tablet adding in 5ml water and with a syringe using 4.5ml of the mixture.

Is this correct?

thank you.


2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

Share this post


Link to post
ChessieCat

Being very patient.  I'll get there - slowly.  ETA mid 2021

ADs:  25 years - 1 unknown, Prozac (caused muscle weakness), Zoloft/sertraline; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after)

Pristiq:  50mg 2012, 100mg beg 2013 (mild Serotonin Toxicity)

Began tapering Oct 2015  Current from 12 Sept 2020:  Pristiq 0.625 mg (compounded)

My tapering program

My Intro (goes to my tapering graph)

My website - includes my brief history + links to videos & information on the web

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

Share this post


Link to post
tish

thank you chessiecatx

Feeling really anxious & my shaking is bad do you think I should reinstate buspirone?


2006 depakote ER 500mg/trazadone 300mg/ zopiclone 7mg.

2011 depakoteER 250mg/ trazadone 150mg/zopiclne 3.75mg.

2019 depakoteER 500mg/trazadone 250mg/zopiclone 7mg reduced to 3.75mg approx 10months later. / buspirone 5mg/ propranolol 10mg as & when needed.

Aug 6th 2020 taper Buspirone 4.5mg.

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Altostrata

What has been your reduction schedule for buspirone? When did your symptoms get worse?


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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