In discussion with @Altostrata, I have decided to start this topic, to differentiate it from the cortisol thread, named "Waking with panic or anxiety - managing the morning cortisol spike".   The reason for differentiating is because the cortisol spikes seem to happen mostly in the morning, while these adrenaline/panic awakenings happen any time during the night. And I am not sure what causes them, but I suspect it's adrenaline. I did a search on SA for "adrenaline" and many users desc