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gdsequoia: quadriceps cramps and eye accommodation problems - paroxetine, Abilify


gdsequoia

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I've got a question.

My tapering is primarily motivated by the side effects I get from my meds:


- cervical dystonia (caused by my long neuroleptic history)
- dry eyes (started when I switched from tolperisone to baclofen)
- muscle pains (mostly WD-related)
- constipation

 

None of these were improving when I was tapering Lexapro (accelerator). And the constipation was getting worse (Lexapro helps me get bowel movements).

When I was tapering Abilify (brake), the dystonia and constipation were improving (rapidly).

 

In light of that info, I think I have 2 options:
1. Microtaper the Abilify (e.g. by 1 or 2 percent a month). Any faster, and my muscle pains will permanently worsen again.
2. Do nothing, as tapering Lexapro makes things worse for me.

 

Option 1 is somewhat dangerous as Abilify is a brake. But since it'd be a microtaper, maybe the danger would be low?

 

(I cannot taper the baclofen or biperiden, as they work wonders for my dystonia, and I'm already on a low dose of them. I've tapered them to the minimal effective dose.)

 

What do you think?

I am not a doctor. My posts are not medical advice.My CYP450 interactions | drug.com interactions

 

Abilify: 34.46mg 26Apr2020; 32.71mg 18May; 31.75mg 13Jun; 30.48mg 22Jun; 29.56mg 28Jun; 28.96mg 30Jul; 28.09mg 20Aug; 27.44mg 28Sep; 26.80mg 20Oct; 26.17mg 22Oct; 25.53mg 28Oct; 26.17mg 30Oct; 26.81mg 4Nov, 26.01mg 7Dec, 26.81mg 13Dec

Antidepressants: Been on Paxil 40mg. Currently Lexapro. 18.54mg 28Jun, 18.16mg 3Jul, 17.8mg 22Jul, 17.44mg 30Jul, 17.09mg 30Aug,  16.92mg 24Sep, 16.25mg 10Oct, 16.58mg 5Nov

Anti-dystonia: tolperisone 300mg and biperiden 2.7mg

Supplements: vitD3 800 IU, chelated magnesium 400mg (+60g pumpkin seeds), melatonin, fish oil, vitE 12mg

 

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That's great progress with the tapering, congratulations! I guess a lot of people (including me) have the same worries as you - what if I get a relapse of my condition after lowering the doses of my m

Because of all the Abilify dose changes you've made recently it would be a good idea to hold for at least 2 months or longer before you start tapering the escitalopram.     It's bette

If they're affecting your health, you may want to taper one of the anticholinergic drugs rather than continuing to taper escitalopram.

  • Moderator Emeritus

Any reduction, however small, would reduce your drug load.  If you cannot get off the drug completely the goal is to use the lowest effective dose.

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Current from 9 Jan 2021:  Pristiq 0.405 mg

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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Yes, @ChessieCat, my question is, which drug should I taper (and how fast), given the above info?

 

I ask because the usual SA.org recommendation is to taper the accelerator, whereas I'm thinking about tapering one of the brakes.

I am not a doctor. My posts are not medical advice.My CYP450 interactions | drug.com interactions

 

Abilify: 34.46mg 26Apr2020; 32.71mg 18May; 31.75mg 13Jun; 30.48mg 22Jun; 29.56mg 28Jun; 28.96mg 30Jul; 28.09mg 20Aug; 27.44mg 28Sep; 26.80mg 20Oct; 26.17mg 22Oct; 25.53mg 28Oct; 26.17mg 30Oct; 26.81mg 4Nov, 26.01mg 7Dec, 26.81mg 13Dec

Antidepressants: Been on Paxil 40mg. Currently Lexapro. 18.54mg 28Jun, 18.16mg 3Jul, 17.8mg 22Jul, 17.44mg 30Jul, 17.09mg 30Aug,  16.92mg 24Sep, 16.25mg 10Oct, 16.58mg 5Nov

Anti-dystonia: tolperisone 300mg and biperiden 2.7mg

Supplements: vitD3 800 IU, chelated magnesium 400mg (+60g pumpkin seeds), melatonin, fish oil, vitE 12mg

 

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  • Moderator Emeritus

SA provides guidelines for a harm reduction approach.  It isn't set in stone that you have to do it the way SA suggests, just like SA recommends tapering only one drug at a time, some members have managed to taper multiple drugs because they have been attuned to their body/symptoms and been very careful and possibly also tolerated medium withdrawal symptoms rather than remain on their drug cocktail and suffering side effects.

 

So, it's up to you.

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Current from 9 Jan 2021:  Pristiq 0.405 mg

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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  • 5 weeks later...

I have painful, irritated, dryish eyes. Altho the ophtalmologist said there's nothing wrong with my eyes - not even dryness. I can barely use electronic screens at home. I'm typing this outside in the cold. :)

 

Thinking abt trying a combo-for-eyes supplement. It contains lutein, zeaxantin, vitamins A/C/E/B2, omega 3, zinc, copper, selenium.

 

Also working on logging my daily eye-symptom pattern. So far, it seems that my eyes get much better when I take my dose of Abilify+Biperiden. Will experiment to see which of the two is the WD-culprit.

I am not a doctor. My posts are not medical advice.My CYP450 interactions | drug.com interactions

 

Abilify: 34.46mg 26Apr2020; 32.71mg 18May; 31.75mg 13Jun; 30.48mg 22Jun; 29.56mg 28Jun; 28.96mg 30Jul; 28.09mg 20Aug; 27.44mg 28Sep; 26.80mg 20Oct; 26.17mg 22Oct; 25.53mg 28Oct; 26.17mg 30Oct; 26.81mg 4Nov, 26.01mg 7Dec, 26.81mg 13Dec

Antidepressants: Been on Paxil 40mg. Currently Lexapro. 18.54mg 28Jun, 18.16mg 3Jul, 17.8mg 22Jul, 17.44mg 30Jul, 17.09mg 30Aug,  16.92mg 24Sep, 16.25mg 10Oct, 16.58mg 5Nov

Anti-dystonia: tolperisone 300mg and biperiden 2.7mg

Supplements: vitD3 800 IU, chelated magnesium 400mg (+60g pumpkin seeds), melatonin, fish oil, vitE 12mg

 

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Does the abovementioned supplement sound good to you guys? Or should I focus more on the logging?

I am not a doctor. My posts are not medical advice.My CYP450 interactions | drug.com interactions

 

Abilify: 34.46mg 26Apr2020; 32.71mg 18May; 31.75mg 13Jun; 30.48mg 22Jun; 29.56mg 28Jun; 28.96mg 30Jul; 28.09mg 20Aug; 27.44mg 28Sep; 26.80mg 20Oct; 26.17mg 22Oct; 25.53mg 28Oct; 26.17mg 30Oct; 26.81mg 4Nov, 26.01mg 7Dec, 26.81mg 13Dec

Antidepressants: Been on Paxil 40mg. Currently Lexapro. 18.54mg 28Jun, 18.16mg 3Jul, 17.8mg 22Jul, 17.44mg 30Jul, 17.09mg 30Aug,  16.92mg 24Sep, 16.25mg 10Oct, 16.58mg 5Nov

Anti-dystonia: tolperisone 300mg and biperiden 2.7mg

Supplements: vitD3 800 IU, chelated magnesium 400mg (+60g pumpkin seeds), melatonin, fish oil, vitE 12mg

 

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  • Moderator Emeritus

When trying anything new it is generally suggested to take them individually and not as a complex.  It is also better to start with a small dose to see how you react.  And it is important to only make one change at a time:

 

the-rule-of-3kis-keep-it-simple-keep-it-slow-keep-it-stable

 

You could try searching SA for the individual ingredients.  Use a search engine and add site:survivingantidepressants.org to the search term.

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Current from 9 Jan 2021:  Pristiq 0.405 mg

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

Link to post

Thanks, Ches.

I am not a doctor. My posts are not medical advice.My CYP450 interactions | drug.com interactions

 

Abilify: 34.46mg 26Apr2020; 32.71mg 18May; 31.75mg 13Jun; 30.48mg 22Jun; 29.56mg 28Jun; 28.96mg 30Jul; 28.09mg 20Aug; 27.44mg 28Sep; 26.80mg 20Oct; 26.17mg 22Oct; 25.53mg 28Oct; 26.17mg 30Oct; 26.81mg 4Nov, 26.01mg 7Dec, 26.81mg 13Dec

Antidepressants: Been on Paxil 40mg. Currently Lexapro. 18.54mg 28Jun, 18.16mg 3Jul, 17.8mg 22Jul, 17.44mg 30Jul, 17.09mg 30Aug,  16.92mg 24Sep, 16.25mg 10Oct, 16.58mg 5Nov

Anti-dystonia: tolperisone 300mg and biperiden 2.7mg

Supplements: vitD3 800 IU, chelated magnesium 400mg (+60g pumpkin seeds), melatonin, fish oil, vitE 12mg

 

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