sunnysideup69 Posted May 28, 2020 Share Posted May 28, 2020 Hi @Deblou46, yes, I can relate. I was doing pretty well after a switch from Citalopram to Venlafaxine. The lockdown and high fatalities in UK definitely caused a big wobble for me. How is your mood generally? I see you also switched. Am in a similar situation as in, waiting for stabilisation before tapering. January 2008 to April 2015 Citalopram 20mg to 5mg, reducing in 50 per cent leaps. Jumped off at 5mg March 2016 used MDMA triggered setback April 2016 Citalopram 10mg October 2016 cut to 5mg, May 2017 cut to 2.5mg May 2018 used MDMA triggered setback June 2018 Citalopram 2.5mg up to 10mg, then back to 5mg July/ August 2018 7.5mg, then 10mg June 2019 updosed to 20mg Citalopram August 2019 cold switch to Venlafaxine 75mg XR Supplements; 1100mg fish oil daily; also 100mg Magnesium Glycinate. Tried Vagifem 10mcg from mid May 2021 to mid June 2021; caused depression, so stopped. Link to comment
Deblou46 Posted July 13, 2020 Author Share Posted July 13, 2020 Hi feeling a little desperate. my story is above but am 8 months now from swapping from 18 years of citalapram to sertraline 100mg. My doctor put me up to 125mg as I was really struggling, but I not making a difference, I know Sertraline will not take away the citalopram withdrawals, but I feel terrible again. Bugs crawling in Head feeling is back with a vengeance. Tongue and throat tension. does this ever go? I thought Sertraline would take away a bit of it. I intend to come of sertraline (although petrified to) I cannot stay on these tablets. I just need some encouragement Thanks Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Sonia009 Posted July 13, 2020 Share Posted July 13, 2020 Hi Deblou I have been on a reduced dose of Citalopram for 11 months from 10mg to 5mg and am still getting many withdrawal symptoms, tinnitus being one of them. I was on them for 10 years. This is not nearly as high a dose as you were on so I can understand how you are still getting withdrawal symptoms from 40mg 8 months later. Your symptoms are probably a combination of citalopram withdrawal and start up effects of setraline, this seems to be a problem for others too, not knowing what is causing what. I can't offer advice on what your next step should be, that is for the experienced people here to advise but I understand your pain and although it seems there is no end to it, you have to believe, like me, that each day is a step nearer to recovery. I commend you for holding down a job through all of this, I couldn't have done that so hats off to you. The covid19 issue has definitely played a part in how we feel both emotionally and physically, it has definitely made my anxiety worse at times. I look around my family and neighbours and I can see how everyones health has been affected in one way or another. All this lockdown time has given us time to overthink matters when it comes to our health which is not good. I hope you find the answers you are looking for to end this nightmare for you. Best wishes. 2008 10 mg Citalopram, 2.5 mg bendroflumethiazide 2021 reduced Citalopram over three years,2023 5.2 mg Citalopram for approx. 1 year Sept 2023 taken off Citalopram and bendroflumethiazide , put on Amitriptyline 10 mg and Ramipril 2.5 mg October 2023 taken off Amitriptyline and Ramipril put on Propranolol 10 mg October 2023 put on Losartan 25 mg November 2023 taken off Losartan on Propranolol 10 mg December 2023 now on 2.5 mg bendroflumethiazide + Citalopram 0.5 mg. February 2024, taken off bendroflumethiazide, on bisoprolol 1.25 mg February 2024, taken off bisoprolol, on ramipril 1.25 mg + 0.5mg Citalopram, stopped ramipril. Link to comment
Deblou46 Posted July 13, 2020 Author Share Posted July 13, 2020 Thanks Sonia I feel awful and it is really upsetting me....... Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus ChessieCat Posted July 14, 2020 Moderator Emeritus Share Posted July 14, 2020 Hi Deblou, Please create your drug signature. This allows us to see your drug history at a glance. Please include any other drugs you have previously or are currently taking. Instructions for what is needed: please-summarize-your-withdrawal-history-in-your-signature This link goes to your signature. Remember to Save after creating/editing it. Account Settings – Create or Edit a signature Thank you. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Moderator Emeritus Dejavu Posted July 14, 2020 Moderator Emeritus Share Posted July 14, 2020 Hi @Deblou46. My heart goes out to you. I was where you are a year ago. I tapered 50mg of sertraline in one month (which is more of a cold turkey than an actual taper). Felt great for a month, then crashed...hard. I reinstated and held on for dear life until I stabilized. It took 10 months. Then I held another two because it felt so good to be well again. By the time I started my taper, I was 99% symptom-free. I'm now down to 20.1mg. There were no words for the mess I was. You can read my intro thread to get a feel for just how bad I was hurting. There were many times I wasn't sure I was going to make it. But I did, and I got better. You will too. You've been at this for 8 long months. You're raising your kids and you're working, and you're pretty doggone tired. I so get it. But if you can just hang on a bit longer, I think you'll see things start to turn around sooner rather than later. Your poor brain is doing everything it needs to in order to return to factory settings. It's been abused and plunged into chaos, courtesy of your doctor, who, in my humble opinion, knows even less about these psych drugs than a first year law student. But the good news is that our brains know how to fix themselves. We are born with everything we need to recover from brain trauma. The term is "neuroplasticity." If you search this site, you will find information on it. You're going to be all right. I wish I could tell you exactly when. We would all like the answer to that question. When someone is in the kind of shape you're in (frightened, traumatized, unsure), sometimes they need reassurance pretty often. I know I did. There's something magical about hearing someone tell you "It's going to be okay," that will keep you going when you don't think you can. Hearing something over and over helps you internalize it. That's why Buddhists chant. That's why Catholics pray their rosaries. That's why some people live by mantras, adages, and mottos. People learn by repetition. I understand that, and want to invite you to reach out to me when you need reassurance and connection during this time. Eventually, you will be able to self-soothe, but at this point in your journey, you might not always be able to do that. So shoot up a flare if you need some support. I'm happy to answer any questions for you that I can. Hang in there! It will be your turn soon! 2016 - Zoloft 50 mg for klonopin w/d Approx. Nov 2017 - successful taper of klonopin; Approx. Jan. 2018 - rapid taper Zoloft over 2 wks - no w/d symptoms; May 2018 - Reinstate 50 mg Zoloft per doctor; Aug 2018 - Rapid taper Zoloft over 3-4 weeks - no w/d symptoms for 1 mo.; Late Oct 2018 - pdoc rx'd 5mg lexapro -took for 1 wk; Early Nov 2018 - Reinstate 25 mg Zoloft; updose to 37.5 on Nov 28, 2018; Nov 30 2018 - returned to 25mg Zoloft upon mod. advice; Dec 9 - Dec10 2018 - 12.5mg zoloft liquid+12.5mg zoloft pill; Dec 11 2018 - 25mg zoloft all liquid; Feb 14 2019 - updosed to 26.25 mg liquid; Mar 6 2019 - updosed to 26.88 mg liquid - new symptoms; Mar 13 2019 - back down to 26.25 mg per mod suggestion Dose Changes: Dec 2 2019 - 5% to 25mg; Jan 14 2020 - 10% to 22.5 (increase in sxs all month); Mar 10-15? 2020, accidental updose to 25mg; Mar 22 2020 - back down to 22.5mg; Apr 12 2020 - 2.5% to 21.94mg; Apr 19 2020 - 2.5% to 21.375mg (symptom increase); May 17 2020 - 2.5% to 20.625mg; May 24 2020 - 2.5% to 20.1mg - Jun 14 2020 - noticed uptick in symptoms settled 2 days later - July 10 2020 - onset of wave Link to comment
Deblou46 Posted July 14, 2020 Author Share Posted July 14, 2020 @manymoretodays @Gridley would this be normal I am really anxious @ChessieCat I did this months ago but it is not showing Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Deblou46 Posted July 14, 2020 Author Share Posted July 14, 2020 Thank you so much @Dejavu I thought sertraline would at least help with WD but this is not the case. Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July upped to 125mg Sertaline Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus ChessieCat Posted July 14, 2020 Moderator Emeritus Share Posted July 14, 2020 1 hour ago, Deblou46 said: I did this months ago but it is not showing Your drug signature is showing now. When we first join we are ask to provide a history. That information is only visible to staff. The signature is different. Thank you for creating it. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Moderator Frogie Posted July 14, 2020 Moderator Share Posted July 14, 2020 Hi: I just thought I’d drop by and see how you are doing? Hopefully things will settle down soon. Hang in there! Take care, Frogie xx PREVIOUS medications and discontinuations: Have been on medications since 1996. Valium, Gabapentin, Lamictal, Prilosec and Zantac from 2000 to 2015 with a fast taper by a psychiatrist. Liquid Lexapro Nov, 2016 to 31-March, 2019 Lexapro free!!! (total Lexapro taper was 4 years-started with pill form) ---CURRENT MEDICATIONS:Supplements:Milk Thistle, Metamucil, Magnesium Citrate, Vitamin D3, Levothyroxine 25mcg, Vitamin C, Krill oil. Xanax 1mg 3x day June, 2000 to 19-September, 2020 Went from .150 grams (average weight of 1 Xanax) 3x day to .003 grams 3x day. April 1, 2021 went back on 1mg a day. Started tapering May 19, 2023. July 28, 2023-approximately .87mg. Dr. fast tapered me at the end and realized he messed up. Prescribe it again and I am doing "slower than a turtle" taper. 19-September, 2020 Xanax free!!! (total Xanax taper was 15-1/2 months-1-June, 2019-19-September, 2020) I am not a medical professional. The suggestions I make are based on personal experience. Link to comment
Deblou46 Posted July 15, 2020 Author Share Posted July 15, 2020 sorry to post again but I feel horrific this wave is horrible and I am scared....8 months now since swapping , I know sertraline wil not take away cit withdrawals but this is horrid. I just want off these evil tablets but cant until settled on sertraline, I did not know anything about withdrawals when i was swapped. Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July upped to 125mg Sertaline Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Administrator Altostrata Posted July 15, 2020 Administrator Share Posted July 15, 2020 3 minutes ago, Deblou46 said: 2nd July upped to 125mg Sertaline This occurred this July 2? Have your symptoms gotten worse since then? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Deblou46 Posted July 15, 2020 Author Share Posted July 15, 2020 I was fine for 3 weeks and it has got worse past few days I think it is WD from citolapram just wanted a bit reassurance. Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Administrator Altostrata Posted July 15, 2020 Administrator Share Posted July 15, 2020 How have your symptoms changed since July 2? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Deblou46 Posted July 15, 2020 Author Share Posted July 15, 2020 I was feeling much better and last few days withdrawals Back tingling in head and face sever anxiety Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus Erell Posted July 16, 2020 Moderator Emeritus Share Posted July 16, 2020 Why did you updose to 125mg on July 2 ? 2006 : 20mg Paxil+Bromazepam. 2008 : cold turkey of both. 2010 : Reinstatement 20mg Paxil + Bromazepam. 2014-June2017 : Switch from Bromazepam to Prazepam, slow taper to 0mg. 2018 to August 2019 : Paxil 20mg taper (3% every 15 days). 22 Aug 2019 updose to 10mg (was at 8.4mg). 25th Sept 2019 To April 2020 : found SA, holding at 10mg Paxil. April 2020 : Paxil 10mg to Prozac 7mg bridge. Details : topic/21457 Current Supplements : magnesium citrate + fish oil Current medication : * 7pm Diazepam : 0.85mg (15 Aug 2022) / 0.95 mg (24 April 2022) / 1mg Diazepam (since 29 Aug 2020) * 8am Prozac : 6.16mg (25 oct 2022, feel awful, slight updose) / 6.08 mg (9 oct 2022) / 6.24mg (11 July 22) / 6.44mg (22 May 22) / 6.64mg (4 Nov 21) / 6.72mg (8 oct 21) / 6.8 mg (15 Sept 21)/ 6.88mg (14 Aug 21)/ 6.92mg (23 Jun 21) I am not a professional, I don't give medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. Link to comment
Deblou46 Posted July 17, 2020 Author Share Posted July 17, 2020 my doctor told me too I was in an anxious mess due to virus i mean can an updose trigger withdrawals? I intend to taper off sertaline when I am levelled Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Deblou46 Posted July 17, 2020 Author Share Posted July 17, 2020 @Altostrata @ChessieCat @Gridley would this be the case? Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus ChessieCat Posted July 18, 2020 Moderator Emeritus Share Posted July 18, 2020 Please update your drug signature so that it remains current: Account Settings – Create or Edit a signature Updosing doesn't cause withdrawals. Updosing too much can cause an adverse reaction. This can be because experiencing withdrawal symptoms can cause your nervous system to become sensitised. When increasing your dose, either an updose or a reinstatement, SA recommends starting with a small dose and increasing slowly by small increments. Please read Post #1 of this topic. Much of the information is applicable to updosing as well as reinstatement. about-reinstating-and-stabilizing-to-reduce-withdrawal-symptoms Please do not suddenly reduce your dose. If you updosed to 125mg sertraline on 2nd July then you have been on the higher dose for just over 2 weeks and your brain will have already made some adjustments. If you return to 100mg it might make things worse. If you would like the mods to assess whether you are taking too much, please provide 3 consecutive days of daily symptom notes. Please read this post which explains what is needed and provides an example: * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Deblou46 Posted July 18, 2020 Author Share Posted July 18, 2020 @ChessieCat i will write down my diary I was having these wd symptoms and my doc said to up to 150 but I didn’t I will not up anymore after I upped I felt great for 3 weeks !!!! Does make sense that updosing can sensitise the nervous system ... do I have to wait until withdrawals completely gone before I taper sertraline ? I want off these drugs x Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus ChessieCat Posted July 19, 2020 Moderator Emeritus Share Posted July 19, 2020 5 hours ago, Deblou46 said: Does make sense that updosing can sensitise the nervous system ... Increasing the dose isn't what sensitises the nervous system. It is when the drug is reduced too quickly and you experience withdrawal symptoms that your nervous system becomes sensitised. After your nervous system has become sensitised taking too much of the drug cause an adverse reaction. When the nervous system is sensitised we also need to be careful when trying anything new. It is best to start with a low dose, make only one change/try something new one at a time to see how we react. the-rule-of-3kis-keep-it-simple-keep-it-slow-keep-it-stable 5 hours ago, Deblou46 said: do I have to wait until withdrawals completely gone before I taper sertraline ? I want off these drugs x It is best to wait until you stabilise. We call in WDnormal. Check out this topic are-we-there-yet-how-long-is-withdrawal-going-to-take We understand that it can be frustrating being on the drug but it is important to be patient. If you try to reduce too soon or by too much it can make things worse. The brain likes consistency. It is better to wait for longer than to risk reducing too soon. The idea is to get off the drug with a little discomfort as possible. Not to get off quickly. It has nothing to do with how strong we are as a person. The brain gets used to getting the drug and we need to take it away gradually which allows the brain to adapt to not getting as much of the drug as we taper. This might help you to understand, especially the part in blue font: On 8/31/2011 at 5:28 AM, Rhiannon said: This is something I posted somewhere else and then saved. I know it's all stuff I've said before, but it bears repeating and further discussion. A lot of people, including healthcare practitioners; in fact, I guess, most people-- are operating from entirely the wrong paradigm, or way of thinking, about these meds. They're thinking of them like aspirin--as something that has an effect when it's in your system, and then when it gets out of your system the effect goes away. That's not what happens with medications that alter neurotransmitter function, we are learning. What happens when you change the chemistry of the brain is, the brain adjusts its chemistry and structure to try to return to homeostasis, or biochemical and functional balance. It tries to restabilize the chemistry. For example: SSRI antidepressants work as "serotonin reuptake inhibitors." That is, they cause serotonin to remain in the space between neurons, rather than being taken back up into the cells to be re-used, like it would be in a normal healthy nondrugged brain. So the brain, which wants to re-establish normal signaling and function, adapts to the higher level of serotonin between neurons (in the "synapse", the space between neurons where signals get passed along). It does this by removing serotonin receptors, so that the signal is reduced and changed to something closer to normal. It also decreases the amount of serotonin it produces overall. To do that, genes have to be turned on and off; new proteins have to be made; whole cascades of chemical reactions have to be changed, which means turning on and off OTHER genes; cells are destroyed, new cells are made; in other words, a complex physiologic remodeling takes place. This takes place over time. The brain does not grow and change rapidly. This is a vast oversimplification of the amount of adaptation that takes place in the brain when we change its normal chemistry, but that's the principle. When we stop taking the drug, we have a brain that has designed itself so that it works in the presence of the drug; now it can't work properly without the drug because it's designed itself so that the drug is part of its chemistry and structure. It's like a plant that has grown on a trellis; you can't just yank out the trellis and expect the plant to be okay. When the drug is removed, the remodeling process has to take place in reverse. SO--it's not a matter of just getting the drug out of your system and moving on. If it were that simple, none of us would be here. It's a matter of, as I describe it, having to grow a new brain. I believe this growing-a-new-brain happens throughout the taper process if the taper is slow enough. (If it's too fast, then there's not a lot of time for actually rebalancing things, and basically the brain is just pedaling fast trying to keep us alive.) It also continues to happen, probably for longer than the symptoms actually last, throughout the time of recovery after we are completely off the drug, which is why recovery takes so long. With multiple drugs and a history of drug changes and cold turkeys, all of this becomes even more complicated. And if a person is started on these kinds of drugs at an early age before the brain has ever completely established normal mature functioning--well, it can't be good. (All of which is why I recommend an extremely slow taper particularly to anyone with a multiple drug history, a history of many years on meds, a history of past cold turkeys or frequent med changes, and a history of being put on drugs at a young age.) This isn't intended to scare people, but hopefully to give you some idea of what's happening, and to help you respect and understand the process so you can work with it; ALSO, because you are likely to encounter many, many people who still believe these drugs work kind of like aspirin, or a glass of wine, and all you need to do is stop and get it out of your system. Now you can explain to them that no, getting it out of your system is not the issue; the issue is, you need to regrow or at least remodel your brain. This is a long, slow, very poorly understood process, and it needs to be respected. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Deblou46 Posted July 19, 2020 Author Share Posted July 19, 2020 13 hours ago, ChessieCat said: Increasing the dose isn't what sensitises the nervous system. It is when the drug is reduced too quickly and you experience withdrawal symptoms that your nervous system becomes sensitised. After your nervous system has become sensitised taking too much of the drug cause an adverse reaction. When the nervous system is sensitised we also need to be careful when trying anything new. It is best to start with a low dose, make only one change/try something new one at a time to see how we react. the-rule-of-3kis-keep-it-simple-keep-it-slow-keep-it-stable I am so sorry to sound a bit stupid, but what does this mean? i reduced citalopram very very quickly 18 years worth in 2.5 months. So moving up to 125 would not make any difference to withdrawals? I will stay at this dose and just stablise before I do anything. and that Sertraline will not take away citalopram withdrawls. Sorry to confirm again Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus ChessieCat Posted July 20, 2020 Moderator Emeritus Share Posted July 20, 2020 8 hours ago, Deblou46 said: what does this mean? You stated: On 7/19/2020 at 6:11 AM, Deblou46 said: Does make sense that updosing can sensitise the nervous system ... I explained that updosing isn't what sensitises the nervous system. It is the withdrawal symptoms which cause sensitivity. 22 hours ago, ChessieCat said: It is when the drug is reduced too quickly and you experience withdrawal symptoms that your nervous system becomes sensitised. In answer to your question: 8 hours ago, Deblou46 said: and that Sertraline will not take away citalopram withdrawls. When you do a cross taper to a different antidepressant you may still get withdrawal symptoms from the first drug because different ADs work in different ways. You can also experience start up/side effects from the new drug. You have also made dose changes. When several changes are made over a short period of time, like you have done, it is difficult to know what is causing what. We strongly encourage members to learn and use Non-drug techniques to cope during the difficult times. This can help you to remain as calm as possible which helps to reduce stress and allows the brain to do what it needs to do. It is also recommended to learn Acceptance. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Moderator Emeritus ChessieCat Posted July 20, 2020 Moderator Emeritus Share Posted July 20, 2020 Please update your drug signature whenever you make a change. That way we can see your history at a glance. Thanks. Account Settings – Create or Edit a signature * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Deblou46 Posted July 20, 2020 Author Share Posted July 20, 2020 @ChessieCat thank you so much I will just have to wait it out until I stabelise Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Deblou46 Posted October 12, 2020 Author Share Posted October 12, 2020 Hi @ChessieCat@Dejavu I am suffering again and cannot see this ever ending, I know people are different, but I have been told the average is 18-24 months for withdrawal to get better? I do not want to up my sertraline as I want to taper down when levelled, but I just don't want to keep living like this, I am not as bad as I was at the beginning of the year. Thanks for your help Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July upped to 125mg Sertaline Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Deblou46 Posted October 12, 2020 Author Share Posted October 12, 2020 can you also tell me where I can find success stories on people that have swapped AD's? Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Deblou46 Posted March 3, 2021 Author Share Posted March 3, 2021 hi all I am now 15 months in to swapping from citolopram to Sertraline and i started intense therapy last week and since then every single symptom I had in withdrawal as come back and I am really scared. I really thought I would feel better by now and this is not the case. Can anyone help I heard the average WD is around 24 months Thanks Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Jennings Posted March 3, 2021 Share Posted March 3, 2021 Did you feel better for a while? When I’m in a wave I feel like I’ve always been in one and it will never end. Med History - 2014 - 2020 - Zoloft, Effexor, Klonopin, Lexapro, Buspar (No longer on any of these) Went to my doctor for an annual and mentioned I was stressed, gave me Zoloft, stopped it after 3 months because it didn't do anything, ended up in withdrawal and was told I had a mental illness. I've been diagnosed Bipolar and Clinically Depressed. Current Med Taper Lamotrigine - 25mg (May 21') -> 24mg (May 23') -> 23mg (July 23') -> 22mg (Aug 23') -> 21mg (Oct 23') -> 20mg (Dec 23') Supplement: Magnesium, Fish Oil Link to comment
Sonia009 Posted March 3, 2021 Share Posted March 3, 2021 Hi Deblou I visited your thread in July of last year and I just want you to know that you are not alone, I too am still experiencing withdrawal symptoms. It's been around 18 months since I reduced to 5mg but am now on 5.2 mg. I think part of my problem has been inaccurate cutting and weighing my tablet and slightly decreasing and increasing my dose. I find my symptoms change i.e., the extreme tiredness and night sweats have gone so too have the nightmares. I still experience some dizziness, headaches and general aches and pains, weird feelings/sensations, weird dreams and tinnitus. Some people recover quicker than others, wish I knew why, seems that you and I are two of the less fortunate ones. I wonder if your dose has been accurate or have you been cutting your tablet? Maybe there is a discrepancy in your dose? Why not tag in one of the moderators and ask for their advice. After reading many posts on this site, it's not unusual for withdrawal to last this long. We just have to give it some more time whilst trying to maintain a healthy lifestyle.😊 2008 10 mg Citalopram, 2.5 mg bendroflumethiazide 2021 reduced Citalopram over three years,2023 5.2 mg Citalopram for approx. 1 year Sept 2023 taken off Citalopram and bendroflumethiazide , put on Amitriptyline 10 mg and Ramipril 2.5 mg October 2023 taken off Amitriptyline and Ramipril put on Propranolol 10 mg October 2023 put on Losartan 25 mg November 2023 taken off Losartan on Propranolol 10 mg December 2023 now on 2.5 mg bendroflumethiazide + Citalopram 0.5 mg. February 2024, taken off bendroflumethiazide, on bisoprolol 1.25 mg February 2024, taken off bisoprolol, on ramipril 1.25 mg + 0.5mg Citalopram, stopped ramipril. Link to comment
Deblou46 Posted March 3, 2021 Author Share Posted March 3, 2021 Thanks Sonia I don’t know who the moderators are ? I actually switched 16 months ago and cannot do anything until stable but thought I would feel better even with sertraline 😞 hope you are ok x Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Sonia009 Posted March 3, 2021 Share Posted March 3, 2021 Hi Deblou I have had help from @ChessieCat and @Gridley and others. Hopefully they can help you or direct you to someone who can now. 2008 10 mg Citalopram, 2.5 mg bendroflumethiazide 2021 reduced Citalopram over three years,2023 5.2 mg Citalopram for approx. 1 year Sept 2023 taken off Citalopram and bendroflumethiazide , put on Amitriptyline 10 mg and Ramipril 2.5 mg October 2023 taken off Amitriptyline and Ramipril put on Propranolol 10 mg October 2023 put on Losartan 25 mg November 2023 taken off Losartan on Propranolol 10 mg December 2023 now on 2.5 mg bendroflumethiazide + Citalopram 0.5 mg. February 2024, taken off bendroflumethiazide, on bisoprolol 1.25 mg February 2024, taken off bisoprolol, on ramipril 1.25 mg + 0.5mg Citalopram, stopped ramipril. Link to comment
Deblou46 Posted March 3, 2021 Author Share Posted March 3, 2021 @ChessieCat @Gridley can you advise ? Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus Gridley Posted March 3, 2021 Moderator Emeritus Share Posted March 3, 2021 (edited) 2 hours ago, Deblou46 said: i started intense therapy What do you mean by "intense therapy"? On 10/12/2020 at 11:05 AM, Deblou46 said: I have been told the average is 18-24 months for withdrawal to get better? There is no average time for withdrawal. It differs from person to person, some longer, some shorter. Your Citalopram taper was very fast. Substituting another drug, as you did with Sertraline, can help lessen withdrawal from the original drug but will not likely eliminate withdrawal. What are your symptoms? It would help us if you were to post a daily symptom chart with specifics as to your symptoms, how you feel before taking your dose, how do feel after and how you feel after your intense therapy. You can use this format below, adapting it to your situation. Please post this every day. 6 a.m. Woke with anxiety 8 a.m. Took 2.5mg Lexapro 10 a.m. Stomach is upset 10:30 a.m. Ate breakfast 11:35 a.m. Got a headache, lasted one hour 12:35 p.m. Ate lunch 4 p.m. Feel a bit better 5 p.m. Took 2.5mg Lexapro 6 p.m. Ate dinner 9:20 p.m. Headache 10:00 p.m. Took 50mg Seroquel 10:20 p.m. Feeling dizzy 10:30 p.m. Fell asleep 2:30 a.m. Woke, took 3mg Ambien (NOT "took 1/2 tablet Ambien") 2:45 a.m. Fell asleep 4:30 a.m. Woke but got back to sleep We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. Magnesium, nature's calcium channel blocker Omega-3 fatty acids (fish oil) Add in one at a time and at a low dose in case you do experience problems. Get supplements that ae single ingredient (not mixed with other types of supplements). Edited March 3, 2021 by Gridley Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of April 1: 6.8mg Taper is 91% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs. Link to comment
Deblou46 Posted March 3, 2021 Author Share Posted March 3, 2021 Thank you i am having therapy going back to my past and how my anxiety all stated I got very upset in the session too should I post my symptoms every day from tomorrow on here ? thank you for your help I think the sertraline has lessened them as they are not as bad but this just seems to be dragging on 🙂 Citalopram 18 years Between 10mg to 40mg Tried tapering off 2012 20 mg WD 6 weeks later reinstated August 2019 tapered down in 2.5 months instructed by psych 40-30mg in one month then 30mg -20mg October 2019 cross tapered to sertraline one week 25mg sertraline 20mg citalopram then 25mg sertraline 10mg Citalopram Nov 2019 start sertraline 50mg 23rd November start 100mg Sertraline 2nd July 2020 - Start 125mg Sertraline 03.03.21 - 15 months since swapped Link to comment
Moderator Emeritus Gridley Posted March 3, 2021 Moderator Emeritus Share Posted March 3, 2021 6 minutes ago, Deblou46 said: should I post my symptoms every day from tomorrow on here ? Yes, please. Also, as I said, include how you feel before the therapy sessions, during and after and whether it feels they are helping. It's very good that the Sertraline has lessened your symptoms. 7 minutes ago, Deblou46 said: i am having therapy going back to my past and how my anxiety all stated I got very upset in the session too You will need to weigh whether the therapy is helping or hurting more. That will have to be your decision. Generally in withdrawal we advise avoiding as much as possible stressful situations. Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of April 1: 6.8mg Taper is 91% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs. Link to comment
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