Xander Posted January 21, 2020 Share Posted January 21, 2020 I took Zoloft for 21 years. It was effective and had little to no side effects. After a prolonged period of feeling good, I tapered down from 150mg to 50mg over the course of a year before being hit with frequent, severe bouts of nausea, typically lasting 5-7 days at a time. Full GI work-up revealed nothing. Over the subsequent 9 months I tried Cymbalta, Effexor, Wellbutrin, Buspar, Lexapro, and Viibryd and none fixed the nausea problem for any length of time. I tapered off the Viibryd over about 5 weeks and had 3 months of feeling pretty good - virtually no nausea and a solid mood. In month 4 the depression returned and in month 5 the nausea returned, this time daily rather than periodic. I then tried to reintroduce in September: - Zoloft - failed in 3 days due to nausea - Trintellix - failed in 8 days due to nausea and worsening depression - Paxil - failed in a month - Amitriptyline - failed in 2 weeks - Mirtazapine - have been on for 2 months. Reduces the nausea but intolerable due to sexual and cognitive side effects. Weak as an antidepressant. While on Mirtazapine, I've tried switching to Viibyrd again but failed in just 5 days. Have also tried Nortriptyline to further reduce the nausea and failed that in a few days. Not sure where to go from here. Most of the drugs make me more depressed. The nausea doesn't go away. I'm frequently suicidal from the constant nausea which has now been with me, more or less uninterrupted, for almost 5 months. Any suggestions or ideas are hugely appreciated 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Moderator Emeritus Sassenach Posted January 22, 2020 Moderator Emeritus Share Posted January 22, 2020 Hello Xander and welcome to SA. This site is run entirely by volunteer Administrators and Moderators, all have been through or going through withdrawal. There are no commercial interests or influences involved . I am sorry you are having such a rough time but you are now in the right place. The site is currently extremely busy so please ensure you answer any requests from staff fully. As you have not included dates or doses for the meds it is difficult to be sure what is happening. You are almost certainly experiencing withdrawal symptoms from all the med changes. In order to advise you we need the drugs info. Please follow the link below to provide this. Please add a signature. Include drugs, doses, dates, and discontinuations & reinstatements in the last 12-24 months. Also include supplements. This will help us give you the most accurate advice we can. Any drugs and supplements prior to 24 months ago can just be listed with start and stop years. Please use actual dates or approximate dates (mid-June, Late October) rather than relative time frames (last week, 3 months ago) Spell out months, e.g. "October" or "Oct."; 9/1/2016 can be interpreted as Jan. 9, 2016 or Sept. 1, 2016. Please leave out symptoms and diagnoses. A list is easier to understand than one or multiple paragraphs. This is a direct link to your signature: http://survivingantidepressants.org/index.php?/settings/signature/ As soon as we have this info. we can advise you. The following links will help you understand what is happening and why multiple drug changes are a bad idea. the-rule-of-3kis-keep-it-simple-keep-it-slow-keep-it-stable/ why-taper-by-10-of-my-dosage/ the-windows-and-waves-pattern-of-stabilization/ derealization-or-depersonalization-dr-and-dp/ dr-joseph-glenmullens-withdrawal-symptom-checklist/ A symptom list is included above. What symptoms are you currently experiencing? Do they get better or worse after taking the meds? As soon as we recieve the drugs info. we can assess your situation. In the meantime DO NOT MAKE ANY CHANGE TO YOUR CURRENT MEDS please. Please feel free to browse the site, it is a wealth of info. Other members threads will give you an insight and the opportunity to share experiences. Again welcome. Sassenach Escitalopram 10mgs from mid 2007 ( can't remember exact date) to 11th Dec 2018 Fentanyl patches ( don't remember dose ) from Nov 2014 to 11 Dec 2018 Quit both cold turkey Dec 2018 Reinstated 3rd March 2019 2.5 mgs. Updosed 8March to 5mgs and holding 25/11/19 Started taper 4.5mgs and holding This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner If you are going through Hell, keep going. NCIS series 15, David MaCallum Link to comment
Xander Posted January 22, 2020 Author Share Posted January 22, 2020 Thank you Sassenach. Updated my signature and am reading through material. Current symptoms are nausea and depression. As stated in the original post, meds mostly seem to make both worse. Sometimes Klonopin can reduce the nausea but not always. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Moderator Emeritus Sassenach Posted January 23, 2020 Moderator Emeritus Share Posted January 23, 2020 I gave you a link to a symptom list. How many of these have you experienced? Nausea seems to be your overiding concern, is that correct? You should have been experiencing a wide range of fluctuating symptoms because of all the drug changes. On 1/21/2020 at 5:26 PM, Xander said: Not sure where to go from here. Most of the drugs make me more depressed. The nausea doesn't go away. I'm frequently suicidal from the constant nausea which has now been with me, more or less uninterrupted, for almost 5 months. It seems possible you are experiencing adverse reactions to the drugs. I am asking @Altostrata who has much more experience than me for her opinion. Sassenach Escitalopram 10mgs from mid 2007 ( can't remember exact date) to 11th Dec 2018 Fentanyl patches ( don't remember dose ) from Nov 2014 to 11 Dec 2018 Quit both cold turkey Dec 2018 Reinstated 3rd March 2019 2.5 mgs. Updosed 8March to 5mgs and holding 25/11/19 Started taper 4.5mgs and holding This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner If you are going through Hell, keep going. NCIS series 15, David MaCallum Link to comment
Xander Posted January 23, 2020 Author Share Posted January 23, 2020 Correct that nausea and depression are chief concerns. Nausea in particular. It’s earth-shattering nausea with no vomiting. It’s so bad it’s life threatening. The other symptoms I’ve experienced seem directly related to the drug I was on: Paxil gave me panic attacks and agitation, Mirtazapine increased my appetite, etc. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Moderator Emeritus Sassenach Posted January 23, 2020 Moderator Emeritus Share Posted January 23, 2020 Thanks Xander. Not normal W/D. We will wait for the boss. Escitalopram 10mgs from mid 2007 ( can't remember exact date) to 11th Dec 2018 Fentanyl patches ( don't remember dose ) from Nov 2014 to 11 Dec 2018 Quit both cold turkey Dec 2018 Reinstated 3rd March 2019 2.5 mgs. Updosed 8March to 5mgs and holding 25/11/19 Started taper 4.5mgs and holding This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner If you are going through Hell, keep going. NCIS series 15, David MaCallum Link to comment
Moderator Onmyway Posted January 23, 2020 Moderator Share Posted January 23, 2020 Hi Xander, I had severe nausea after quitting and reinstating citalopram. It went on for 4-5 months. It returns occasionally when I make cuts or when I have other psychological stressors now but is much better than the daily one. Your case is different in that you've tried so many drugs. I suspect that it is possible that the nausea actually causes the depression - that yucky feeling when your guts want to come out can be quite debilitating and depressing. I'm really sorry you are going through it. I don't really have advice - I drank ginger tea and ate ginger cookies for a long time and they were somewhat helpful but not that much. I also discovered that some supplements made it worse (L-theanine) and some drugs made it worse (clonazepam, alprazolam). Hope you feel better soon. It does get better but not sure how long you will have to endure it. "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Administrator Altostrata Posted January 24, 2020 Administrator Share Posted January 24, 2020 Hello, Xander. What are the dosages you tried here? Please also add dosages to your signature notes. On 1/21/2020 at 9:26 AM, Xander said: - Zoloft - failed in 3 days due to nausea - Trintellix - failed in 8 days due to nausea and worsening depression - Paxil - failed in a month - Amitriptyline - failed in 2 weeks - Mirtazapine - have been on for 2 months. Reduces the nausea but intolerable due to sexual and cognitive side effects. Weak as an antidepressant. What is your current daily drug schedule, with times of day? Are your symptoms better or worse at any particular times of day? It seems nausea is your hallmark withdrawal symptom. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Xander Posted January 24, 2020 Author Share Posted January 24, 2020 Altrostrata - Dosages are in my signature. Currently on Mirtazapine 15mg at night. Nausea tends to be worst first thing in morning. Sometimes can be triggered by a meal. No answers from a half-dozen gastrointerologists. Onmyway - thank you. I'm glad your nausea went away. And yes, the nausea is a major contributor to my depression. I'm in therapy to help cope. And every single person I've told this to mentions ginger - unfortunately it doesn't help. Neither does any nausea medication. The only thing that occasionally helps in clonazepam. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Administrator Altostrata Posted January 24, 2020 Administrator Share Posted January 24, 2020 I need to know the o'clock for your drug schedule and symptoms. What are your "other intolerable side effects"? What times of day do they occur? When you went back to 150mg Zoloft, what does "fail" mean? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Xander Posted January 24, 2020 Author Share Posted January 24, 2020 I take Mirazapine with dinner so typically 8pm or so. The "other intolerable side effects" are sexual side effects (diminished libido and functioning) and thinking problems (memory issues, difficulty organizing and articulating thoughts, etc). Failing off Zoloft means it didn't fix the nausea. It was tolerable otherwise. Other drug fails were a variety of reasons: sexual side effects, suicidal ideation, and nausea. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Administrator Altostrata Posted January 24, 2020 Administrator Share Posted January 24, 2020 Please keep daily notes of times of day you take your drugs, their dosages, and your symptoms throughout the day. You can post 24 hours of notes at a time in this topic, in a simple list format with time of day on the left and notation (symptom or drug and dosage) on the right. This will help identify the source of your symptoms. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Xander Posted January 24, 2020 Author Share Posted January 24, 2020 ?? I only take one drug, at the same time each day. Mirtazapine 15mg at about 8pm. The nausea I've experienced has been across 12 medications over almost 2 years as noted in my signature. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Xander Posted February 13, 2020 Author Share Posted February 13, 2020 Any other ideas? 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
anna7887 Posted October 1, 2020 Share Posted October 1, 2020 Have you found any relief? I’m micro tapering Zoloft and 2 months ago I was slammed with nausea 24/7... bloodwork, ultrasound , etc normal.. likely going for an endoscopy soon. I can’t help but think coming off a decade long Zoloft use is messing with my gut.. it’s the worst and I’m so worried I have cancer or something. Ugh. Have you tried dietary changes like no gluten, dairy, etc? I think I’m going to step up my clean eating and try celery juice... -given Prozac at 12 due to panic attacks for 6months -Med free until 2008 when I was 20 years old -2008-2009- Pristiq, followed by quick taper. -1/10-Rxed 50mg Zoloft & .5mg Klonopin daily after a death in the family - 2/2012 Successfully micro tapered off .5mg of Klonopin after taking daily for 2 years. Started 100mg of Trazadone for sleep . - Oct 2013- Quickly tapered off trazadone. Bad idea! But finally trazadone free. - July 2015- present Became very ill with lyme like sxs -August 2018-present. Started micro taper off 50mg of Zoloft via liquid titration ... - July 2021- down to 3mg.. had digestive issues so got an endoscopy and major flair! -March 2022- tried cross tapers to Prozac and lexapro did not work. Jumped off everything. -Present: Med free and pregnant! Aside from some health issues I’m doing better than expected!! Link to comment
Moderator Emeritus ChessieCat Posted October 1, 2020 Moderator Emeritus Share Posted October 1, 2020 On 1/25/2020 at 6:32 AM, Altostrata said: Please keep daily notes of times of day you take your drugs, their dosages, and your symptoms throughout the day. You can post 24 hours of notes at a time in this topic, in a simple list format with time of day on the left and notation (symptom or drug and dosage) on the right. This will help identify the source of your symptoms. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Xander Posted October 1, 2020 Author Share Posted October 1, 2020 Unfortunately, no. Just finished acupuncture and hypnotherapy. Still nauseous 24/7. More tests came back negative. I’ve been dairy and gluten free for 10+ years so nothing to modify there. Sorry to hear you’re going through it too. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Mia1 Posted February 13, 2021 Share Posted February 13, 2021 How are you feeling? Completely drug free 11/26/22 🎉 Supplements: Magnesium citrate: 250 mg; Fish oil: 1200 mg “When we are no longer able to change a situation, we are challenged to change ourselves.” - Victor Frankl Link to comment
Xander Posted February 13, 2021 Author Share Posted February 13, 2021 STILL nauseous. 14 gastroenterologists, 6 hospitals, 3 years and no answers. Going to Mayo Clinic in April. Currently attempting to taper down, possibly off, Cymbalta 60mg (my only psych med). Unbelievable. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
Mia1 Posted February 14, 2021 Share Posted February 14, 2021 I’m so sorry to hear that, it is truly unbelievable. I’m experiencing a lot of nausea and gastrointestinal issues at the moment myself so I can’t imagine. Are you working? I hope you hear good news at the Mayo Clinic, my thoughts are with you. You’ll get better. Completely drug free 11/26/22 🎉 Supplements: Magnesium citrate: 250 mg; Fish oil: 1200 mg “When we are no longer able to change a situation, we are challenged to change ourselves.” - Victor Frankl Link to comment
Xander Posted February 22, 2021 Author Share Posted February 22, 2021 Working but it’s very difficult, even from home. Thank you very much. Wish you good luck as well. 1996 - 2017 - Zoloft: 50mg to 150mg 2017 - 2018: Taper Zoloft from 150mg to 50mg over the course of 1 year. Begin experiencing crippling bouts of nausea with no underlying explanation May 2018 - June 2018: Go back up to 150mg Zoloft and fail. Cross taper to Cymbalta 40mg August 2018 - November 2018: cross taper to Effexor 75mg. Attempt to add Wellbutrin and Buspar and each fail November 2018 - February 2019: cross taper to Lexapro 10mg fails February 2019 - April 2019: cross taper to Viibryd 20mg fails April 2019: taper off Viibryd over 5 weeks May 2019 - August 2019: honeymoon period of no nausea or depression ends in August. Nausea now daily rather than periodic. September 2019: Fail off Zoloft 25mg (3 days) and Trintellix 10mg (8 days) October 2019: Fail off Paxil 10mg and Amitrptyline 10mg November 2019 to present: cross taper to 15 mg of Mirtazapine. Reduces but doesn't eliminate nausea. Other intolerable side effects. January 2019: attempt to add Nortrptyline (fail in 5 days) and cross taper to Viibryd (fail in 5 days). Still on Mirtazapine 15 mg. Link to comment
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