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Chaotnr1: Effexor, Trazodone cold turkey


Chaotnr1

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Hi Everyone

 

I just wanted to introduce myself.

I have been lurking this forum for long enough now. 🙂

Male, 28

 

My story starts in November 2018 when I went partying with a few friends and consumed different recreational drugs (MDMA, Cocaine, Speed and Alcohol).

I wasn't new to these drugs but I made the huge mistake to not test any substance and not dosing correctly.

However I didn't feel bad throughout that weekend and the hangover was as expected.

After four days the panic attacks and the depression started and it just did not get any better over time.

A month later I had enough and went to my GP who immediately put me on Effexor and Seroquel.

Later on Seroquel has been exchanged first to Mirtazapine and then Trazodone (see signature).

 

The drugs definitely helped with the panic attacks but Side Effect were just unbearable

I felt 40 years older, manic, aggressive, suicidal, without any motivation and completely emotionally numb.

There was just no way I would stay on this horrible stuff any longer so I went cold turkey after two months.

 

The first two months were kind of ok but I still felt drugged.

After that the emotional symptoms kicked in and it became a fight for survival day by day.

I will not go into detail about it because you probably all know what I am talking about.

Sixth month later I made some progress, the symptoms became a little bit less intense and I had some windows.

Over the next four months I made some further minuscule improvements, windows became longer.

I started to feel kind of stable in my recovery, it gave me some hope that I didn't lose my job and my girlfriend throughout all this time.

 

Next month I will be drug free for a year but it is still a massive struggle every day.

Right now I seem to be in a long wave (5 weeks so far) with a great change of symptoms.

The anxiety and the panic attacks have become a lot worse recently and there are a lot of physical symptoms like dizziness, nausea, loss of appetite and generally feeling miserable.

I have become less active, less motivated to exercise but on the other hand I am also feeling kind of ok with it.

Also my sleep seems to have changed quite a bit, I didn't have very bad insomnia so far only very intense and draining dreams.

They are mostly gone now but instead I am sleeping two to three hours less per night.

I try to see these changes as my brain being at work 🙂 

 

I can't differentiate if I am still in Withdrawal or if this is the after effect of the recreational drug incident (any ideas?).

All I can hope for is that my brain will heal the same way as it does if I had taken psychiatric drugs only.

 

Throughout my life I only had a few bouts of mild depression and anxiety (and three mild panic attacks), nothing I couldn't cope with.

I also have never been on any psychiatric drug.

 

I will try to document my recovery in this topic.

Massive thanks to the people of this forum without you I would probably have gone back on psychiatric drugs a long time ago.

You can't imagine how much hope I got reading through these pages! 🙂

2018 Mid November: Recreational Drug Incident triggering withdrawal-like symptoms

2018 Mid December: Start Venlafaxine XR 75mg, Seroquel 25mg
2019 Early January: Switch Seroquel to Mirtazapine 15mg
2019 Mid January: Switch Mirtazapine to Trazodone 50-150mg
2019 Mid February: All medication -> Cold Turkey

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  • Moderator Emeritus

Welcome to SA, Chaotnr.

 

The symptoms you describe are typical withdrawal symptoms caused by the frequent psychiatric drug changes and the cold turkey.  I would say that your brain will heal the same as if you had been on the psychiatric drugs only, that is to say, you will heal, though it will take some time.

 

So that you have a better understanding of what you're experiencing, here is some information on withdrawal and healing.

 

What is withdrawal syndrome.

 

Daily Checklist of Antidepressant Withdrawal Symptoms (PDF)

 

The Windows and Waves Pattern of Stabilization

 

When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur.

 

These explain it really well:

 

Video:  Healing From Antidepressants - Patterns of Recovery

 

   On 8/30/2011 at 2:28 PM,  Rhiannon said: 
When we stop taking the drug, we have a brain that has designed itself so that it works in the presence of the drug; now it can't work properly without the drug because it's designed itself so that the drug is part of its chemistry and structure. It's like a plant that has grown on a trellis; you can't just yank out the trellis and expect the plant to be okay. When the drug is removed, the remodeling process has to take place in reverse. SO--it's not a matter of just getting the drug out of your system and moving on. If it were that simple, none of us would be here. It's a matter of, as I describe it, having to grow a new brain. I believe this growing-a-new-brain happens throughout the taper process if the taper is slow enough. (If it's too fast, then there's not a lot of time for actually rebalancing things, and basically the brain is just pedaling fast trying to keep us alive.) It also continues to happen, probably for longer than the symptoms actually last, throughout the time of recovery after we are completely off the drug, which is why recovery takes so long.

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

Magnesium, nature's calcium channel blocker 

 

Omega-3 fatty acids (fish oil) 

 

 Add in one at a time and at a low dose in case you do experience problems.

 

This is your Introduction topic, where you can document your recovery, ask questions and connect with other members.  We're glad you found your way here.

 

 

 

 

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements

Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium

Feb. 2021, begin 10%/4 week taper of 18.75mg Valium 

End 2021  year 1 of Valium taper at 6mg

End 2022 year 2 of Valium taper at 2.75mg 

End 2023 year 3 of Valium taper at 1mg

Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper.

Taper is 95% complete.

 

Imipramine 75 mg daily since 1986.  Jan.-Sept. 2016 tapered to 14.4mg  

March 22, 2022: Begin 10%/4 week taper

Aug. 5, 2022: hold at 9.5mg and shift to Valium taper

Jan. 24, 2024: Resume Imipramine taper.  Current dose as of April 1: 6.8mg

Taper is 91% complete.  

  

Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase


I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs.

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Thank you for the warm welcome and the encouragement Gridley!

 

I have studied the information provided on this forum in detail and it helped me tremendously on getting an understanding of the withdrawal process and how to cope with it.

This forum is absolutely invaluable for people who have been left alone and suffering by their medical providers.

 

For documentation purposes, here is the list of supplements I am currently taking and also took for most of my withdrawal:

- Omega 3

- ZMB (combination of Zink, Magnesium, Vitamin B6)

- Vitamin C,K,D3

- Creatine

- Whey Isolate / Casein / Essential Amino Acids (EAA)

- Curcuma

- CBD Oil (only from time to time)

 

Tried but stopped supplements (no negative reaction but also no benefit):

- GABA

- Seriphos

- 5-HTP

- L-Tryptophan

 

I tried the following recreational drugs:

- Caffeine: spikes anxiety, sometimes ok, green tea is ok

- Alcohol: spikes anxiety, leads to depression, possible trigger for waves

- Weed: spikes anxiety, no relaxation possible, not enjoyable

- Psilocybin: ok in very small doses and a very calm environment but not really enjoyable

2018 Mid November: Recreational Drug Incident triggering withdrawal-like symptoms

2018 Mid December: Start Venlafaxine XR 75mg, Seroquel 25mg
2019 Early January: Switch Seroquel to Mirtazapine 15mg
2019 Mid January: Switch Mirtazapine to Trazodone 50-150mg
2019 Mid February: All medication -> Cold Turkey

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  • 3 weeks later...

Update 20.02.2020

 

I am now 1 year off of the drugs and it is 15 months after the recreational drug incident.

Not a lot has changed since last month.

My anxiety seems to be getting worse and the depression is as deep as always.   

 

Yesterday I had a very important certification test for my job.

Even though I was sure I would pass (fairly easy test), I started to panic about an hour before my appointment.

It was so bad that I had to take 0.5mg of Lorazepam or I wouldn't even have made it out of the house.

The benzo helped tremendously and I was able to score full points, but it left a bitter aftertaste.

I haven't had a reason to take a benzo for almost a year.

I am honestly questioning if I have made any progress regarding my anxiety.

It's like I am getting an anxiety or even a panic attack from the slightest feeling of discomfort.

Is this still normal?

 

On a positive note, the brain zaps are 90% gone.

It took a whole year for them to mostly disappear, I can't even provoke them anymore.

My sleep has also gotten a bit better.

And I am also putting more effort into photography, one of my remaining hobbies.

 

Trying to push through this as good as I can.

Stay strong everyone! 🙂

2018 Mid November: Recreational Drug Incident triggering withdrawal-like symptoms

2018 Mid December: Start Venlafaxine XR 75mg, Seroquel 25mg
2019 Early January: Switch Seroquel to Mirtazapine 15mg
2019 Mid January: Switch Mirtazapine to Trazodone 50-150mg
2019 Mid February: All medication -> Cold Turkey

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  • 2 years later...

Hi all

 

I hope everyone i doing fine!

I haven't posted in a long time.

I am now 3 years off of any psychoactive medication. (CT after only two months use)

Even though there have been some improvements, I am still struggling a lot and I am far from recovered.

 

There has been a recent happening which left me very confused and maybe some of you could help me make some sense of it.

 

I recently changed my GP and I thought I would use this opportunity to get my blood checked.

So I went to the GP to discuss the results, already expecting them to be perfectly fine like they have been in all the previous times.

But this time my doctor told me my thyriod is slightly overactive (TSH of 0.4).

So we did an ultrasound and an antibody test.

On the ultrasound everything was normal but my antibody test came back positive.

I don't know which antibodies exactly but my doctor diagnosed me with Hashimotos.

Now, I don't know if this is something new or if my blood has simply not been tested for thyriod activity in the previous tests. (I am currently trying to get an answer to that)

 

This all left me with quite a lot of questions, like if I can actually trust this diagnosis?

Do I really have Hashimotos or is this is all just another weird side effect of withdrawal?

Could the antibodies disappear when my withdrawal ends?

Or is my withdrawal actually over and the symptoms I currently have are only from Hashimotos? Did I even have a withdrawal or have the Antidepressants "just" triggered Hashimotos?

 

My current symptoms also don't help much with an explanation.

I have some symptoms which match with the high thyroid activity that my blood test shows like anxiety, restlessness, constantly high heart rate and air hunger.

But there are also a lot of symptoms which contradict it like depression, zero motivation, sluggishness, fatigue, brain fog and high cold sensibility.

 

Has anyone gone through something similar or has an idea how I should handle this situation?

 

I am going to have an appointment with an endocrinologist soon, maybe I will get some answers there.

 

Thanks!

2018 Mid November: Recreational Drug Incident triggering withdrawal-like symptoms

2018 Mid December: Start Venlafaxine XR 75mg, Seroquel 25mg
2019 Early January: Switch Seroquel to Mirtazapine 15mg
2019 Mid January: Switch Mirtazapine to Trazodone 50-150mg
2019 Mid February: All medication -> Cold Turkey

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  • Moderator Emeritus

* NO LONGER ACTIVE on SA *

MISSION ACCOMPLISHED:  (6 year taper)      0mg Pristiq  on 13th November 2021

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

Post 0 updates start here    My tapering program     My Intro (goes to tapering graph)

 VIDEO:   Antidepressant Withdrawal Syndrome and its Management

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  • Administrator

Hello, @Chaotnr1

 

In the US, a TSH of 0.4 would be considered negligible. Many people have Hashimoto's antibodies but never develop hypothyroidism justifying treatment. Hashimoto's antibodies can go up and down.

 

It's alway a good idea to educate oneself about your potential medical conditions and treatments -- reading good sources rather than asking around on social media, where you may get answers that are uninformed.

 

This is a site for going off drugs. There are other online communities specifically about Hashimoto's and thyroid tests. Your questions would be bettered answered in those communities.

 

 

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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