Jump to content
Andie

Massabki, 2020, Selective serotonin reuptake inhibitor ' discontinuation syndrome' or withdrawal

Recommended Posts

Andie

“Overt acknowledgment that SSRI use can result in dependence and withdrawal SSRI discontinuation syndrome or withdrawal allows patients to be truly informed in their decisions, and helps inform strategies for safe tapering of these widely prescribed drugs.”

 

 Massabki, I., & Abi-Jaoude, E. (n.d.). Selective serotonin reuptake inhibitor ‘discontinuation syndrome’ or withdrawal. The British Journal of Psychiatry, 1-4. doi:10.1192/bjp.2019.269. 

 

Selective serotonin reuptake inhibitor ‘discontinuation syndrome’ or withdrawal

 

 Massabki, I & Abi- Jaoude, E. 

 

https://doi.org/10.1192/bjp.2019.269 Published online by Cambridge University Press: 06 January 2020

 

Summary

Attempts to define selective serotonin reuptake inhibitor (SSRI) withdrawal with the term ‘discontinuation syndrome’ are not supported by evidence. Acknowledging that SSRI use can result in dependence and withdrawal allows patients to be better informed around decisions related to these drugs, and helps inform strategies for safe tapering as appropriate. 

 

See link below for further discussion of this article. 

https://www.mentalhealthexcellence.org/researchers-antidepressant-withdrawal-not-discontinuation-syndrome/

 


Current Dose

0.5mcg Clonidine and 1.25 Diazepam PRN for treatment of iatrogenic hypertension. 

2010 .Prescribed Pristiq 100 mg in July by GP

2010 .Reduced to 50mg by splitting and weighing. Held at 50mg

2014. Reduced from 50-35 .Held at 35mg. 

2017. Taper from 35mg commenced using compounded Desvenlafaxine

2018. 23/06 13.5mg. 21/07  12.5mg. 25/08 11.5mg. 09/2018 10mg. 14/11 11mg (updose) 21/11 -12mg (updose)

2019. Still holding at 12mg and stuck. 

2020. January 2019 Prozac Bridge-- Prozac 2.5 to 10mg and

Pristiq 23rd Jan 6mg/ 27th Jan 5mg/ 28th Jan 3mg/ 30 Jan 0

Prozac 6th Feb 9.5mg. Vitamin D3 5000iu with K2

Magnesium Glycinate with Glycine and Passionflower  600mg 

Share this post


Link to post
Share on other sites
Andie

I would be so grateful if someone could fix the spelling error in the title. Predictive text got me. 


Current Dose

0.5mcg Clonidine and 1.25 Diazepam PRN for treatment of iatrogenic hypertension. 

2010 .Prescribed Pristiq 100 mg in July by GP

2010 .Reduced to 50mg by splitting and weighing. Held at 50mg

2014. Reduced from 50-35 .Held at 35mg. 

2017. Taper from 35mg commenced using compounded Desvenlafaxine

2018. 23/06 13.5mg. 21/07  12.5mg. 25/08 11.5mg. 09/2018 10mg. 14/11 11mg (updose) 21/11 -12mg (updose)

2019. Still holding at 12mg and stuck. 

2020. January 2019 Prozac Bridge-- Prozac 2.5 to 10mg and

Pristiq 23rd Jan 6mg/ 27th Jan 5mg/ 28th Jan 3mg/ 30 Jan 0

Prozac 6th Feb 9.5mg. Vitamin D3 5000iu with K2

Magnesium Glycinate with Glycine and Passionflower  600mg 

Share this post


Link to post
Share on other sites
FindRest
7 hours ago, Andie said:

I would be so grateful if someone could fix the spelling error in the title. Predictive text got me. 


“Reputable inhibitor”...that explains why I am the way I am, lol!!!


1988-1996  Various AD’s, all classifications.  

1996-2019  Effexor XR 37.5mg to 150mg. Jan 2017 onward, 37.5 mg.

2019  Apr 11: Latuda 20mg added to Effexor.  Apr 22: L to 40mg.  May 14: L to 20mg.  May 27: L to 10 mg for 3 days then ct (dr’s orders). Continue Effexor 37.5.  Jun 10: Rexulti .5 mg added. Incr to 1mg.  Jun 15: Rex to .5mg.  Jul 1-24: taper Rex to .25mg over couple of weeks then off.  Jul 24: CT Effexor (per dr’s orders)  Sep 9-19: Viibryd (low dose, not sure mg), CT (dr’s orders).  Sep 23-27: Trintellix (low dose). CT (dr’s orders).  Sep 28:  Prozac 10mg.  Oct 24:  Began rapid taper off Prozac (every other day for wk) began Pristiq 25mg for 10 days, then 50mg after that.  Dec 31-Jan 31, 2020:  Pristiq 25mg. 

2020  Feb 1: CT Pristiq due to serious side effects incl high BP w pre-existing heart condition.   Feb 1: Effexor XR (10 large beads from 37.5 capsule).  Feb 3: 14 L beads.  Feb 15: 14 L beads+2 med beads.  Feb 17: 15L + 5M beads (25mgbw or 7.56mgai).

Current: Mar 1, 2020: Effexor XR (15 large beads + 7 medium beads, 30mgbw or 9.072mgai)

 

Other current meds: Ambien 10mg nightly (2012), clonazepam .125mg nightly (May, 2019), omeprazole 20mg (alt w famotidine 20mg, since Oct 2019), Synthroid 125 mcg (1985), Premarin .625mg (2002), Miralax capful/day (2014), fluticasone nasal once/day (mid-2018), cetirizine 10mg nightly (late-2018) .  Supplements: D3 25mcg, probiotic

Share this post


Link to post
Share on other sites
Altostrata

Done! Thanks for posting this, and in the format we like for Journals, Andie.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

Share this post


Link to post
Share on other sites

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

×
×
  • Create New...

Important Information

Terms of Use Privacy Policy