Jump to content

senseless: tapering off 25mg Seroquel/quetiapine after being on it for a month


senseless

Recommended Posts

Another night of blissful 7 hours of consolidated sleep woo! The tapering is following a pretty regular pattern now generally 1st night or 2 is a bit rough but by the 3rd/4th im back to 6-7 hours sleep.

6.01.20 - 6.02.20: Seroquel/Quetiapine 25mg

7.02.20 - 13.02.20: Attempted CT ran into extreme rebound insomnia

13.02.20 - 04.07.20Reinstated and holding Seroquel/Quetiapine 13.5mg, 1mg Circadin 

Began Tapering of Seroquel

04.07.20 - Quetiapine 13mg 12.07.20 - Quetiapine 12.5mg 20.07.20 - Quetiapine 12mg 28.07.20 - Quetiapine 11.5mg

02.08.20 - Quetiapine 11.mg 06.08.20 - Quetiapine 10.5mg 10.08.20 - Quetiapine 10mg 15.08.20 Quetiapine 9.5mg

18.08.20 Quetiapine 9mg 23.08.20 Quetiapine 8.527.08.20 Quetiapine 8mg 31.08.20 Quetiapine 7.75mg02.09.20 Quetiapine 7.5mg 06.09.20 Quetiapine 7.25mg 08.09.20 Quetiapine 7mg 12.09.20 Quetiapine 6.75mg 14.09.20 Quetiapine 6.5mg 19.09.20 Quetiapine 6.25mg 21.09.20 Quetiapine 6mg 24.09.20 Quetiapine 5.75mg 01.10.20 Quetiapine 5.5mg 03.10.20 Quetiapine 5.25mg 05.10.2020 Quetiapine 5mg 09.10.2020 Quetiapine 4.75mg 12.10.2020 Quetiapine 4.5mg 14.10.2020 Quetiapine 4.25mg 17.10.2020 Quetiapine 4mg 21.10.2020 Quetiapine 3.75mg 24.10.2020 Quetiapine 3.5mg 1.11.2020 Quetiapine 3 mg 7.11.2020 Quetiapine 2.5 mgs 13.11.2020 Quetiapine 2 mg 16.11.2020 Quetiapine 1.5 mg 20.11.2020 Quetiapine 1.25mg 23.11.2020 Quetiapine 1mg 26.12.2020 Quetiapine 0.75mg 16.01.2020 Quetiapine 0.5mg 17.02.2020 Quetiapine 0.25mg

Link to post
  • 2 months later...
  • Replies 117
  • Created
  • Last Reply

Top Posters In This Topic

  • senseless

    64

  • Shep

    27

  • Altostrata

    10

  • Gridley

    4

Top Posters In This Topic

Popular Posts

Hello update time, Dropped to 0.25mg last week. Its going well so far, sleep is about 7-8 hours even had a nice 7 hours consolidated sleep couple days ago. Hoping not to be hit by delayed withdr

Just thought id give a positive update for once.   I slept for a consolidated 6.5 hours for the first time since probably march.    Seems like my sleep is actually getting better a

Quick update. Sleep is returning to a normal level now around 7-8 hours now, which is good. I'm not sure how much longer I should hold at this dose, I'm thinking at least another week  or two ma

Hello overdue update time.

 

I want to start things on a positive note on the 20.11.2020 I slept for a consolidated 7.5 hours! woo!

Anyway! As you can see from my signature I increased the rate of my taper quite a bit and may of pushed it a bit too hard. As I hit a wave at 1mg with my sleep deteriorating and had a small relapse of suicidal ideation. But after doing an unfortunately necessary hold I'm doing ok again.

Sleeping decent enough 6-8 hours fractured, feeling well rested. Which I was not a couple weeks ago, withdrawal has made me cherish being well rested. 

6.01.20 - 6.02.20: Seroquel/Quetiapine 25mg

7.02.20 - 13.02.20: Attempted CT ran into extreme rebound insomnia

13.02.20 - 04.07.20Reinstated and holding Seroquel/Quetiapine 13.5mg, 1mg Circadin 

Began Tapering of Seroquel

04.07.20 - Quetiapine 13mg 12.07.20 - Quetiapine 12.5mg 20.07.20 - Quetiapine 12mg 28.07.20 - Quetiapine 11.5mg

02.08.20 - Quetiapine 11.mg 06.08.20 - Quetiapine 10.5mg 10.08.20 - Quetiapine 10mg 15.08.20 Quetiapine 9.5mg

18.08.20 Quetiapine 9mg 23.08.20 Quetiapine 8.527.08.20 Quetiapine 8mg 31.08.20 Quetiapine 7.75mg02.09.20 Quetiapine 7.5mg 06.09.20 Quetiapine 7.25mg 08.09.20 Quetiapine 7mg 12.09.20 Quetiapine 6.75mg 14.09.20 Quetiapine 6.5mg 19.09.20 Quetiapine 6.25mg 21.09.20 Quetiapine 6mg 24.09.20 Quetiapine 5.75mg 01.10.20 Quetiapine 5.5mg 03.10.20 Quetiapine 5.25mg 05.10.2020 Quetiapine 5mg 09.10.2020 Quetiapine 4.75mg 12.10.2020 Quetiapine 4.5mg 14.10.2020 Quetiapine 4.25mg 17.10.2020 Quetiapine 4mg 21.10.2020 Quetiapine 3.75mg 24.10.2020 Quetiapine 3.5mg 1.11.2020 Quetiapine 3 mg 7.11.2020 Quetiapine 2.5 mgs 13.11.2020 Quetiapine 2 mg 16.11.2020 Quetiapine 1.5 mg 20.11.2020 Quetiapine 1.25mg 23.11.2020 Quetiapine 1mg 26.12.2020 Quetiapine 0.75mg 16.01.2020 Quetiapine 0.5mg 17.02.2020 Quetiapine 0.25mg

Link to post
  • 5 weeks later...
senseless

Update.

Currently at 0.5mg woo! Almost there.

 

I was originally planning on jumping off at 0.25mg, but I'm not sure about that anymore. 

It seems even at tiny doses Seroquel is very potent.

As the jump from 0.75mg to 0.5mg,  although initially fine. The past 5 days have seen my sleep time reduced to around 6 hours a night, compared to 7-8 hours I was getting at 0.75mg. 
 

I'm going to continue holding for a while and hope my sleep improves. May need to updose to 0.6mg but hope it doesn't come to that :)

 

6.01.20 - 6.02.20: Seroquel/Quetiapine 25mg

7.02.20 - 13.02.20: Attempted CT ran into extreme rebound insomnia

13.02.20 - 04.07.20Reinstated and holding Seroquel/Quetiapine 13.5mg, 1mg Circadin 

Began Tapering of Seroquel

04.07.20 - Quetiapine 13mg 12.07.20 - Quetiapine 12.5mg 20.07.20 - Quetiapine 12mg 28.07.20 - Quetiapine 11.5mg

02.08.20 - Quetiapine 11.mg 06.08.20 - Quetiapine 10.5mg 10.08.20 - Quetiapine 10mg 15.08.20 Quetiapine 9.5mg

18.08.20 Quetiapine 9mg 23.08.20 Quetiapine 8.527.08.20 Quetiapine 8mg 31.08.20 Quetiapine 7.75mg02.09.20 Quetiapine 7.5mg 06.09.20 Quetiapine 7.25mg 08.09.20 Quetiapine 7mg 12.09.20 Quetiapine 6.75mg 14.09.20 Quetiapine 6.5mg 19.09.20 Quetiapine 6.25mg 21.09.20 Quetiapine 6mg 24.09.20 Quetiapine 5.75mg 01.10.20 Quetiapine 5.5mg 03.10.20 Quetiapine 5.25mg 05.10.2020 Quetiapine 5mg 09.10.2020 Quetiapine 4.75mg 12.10.2020 Quetiapine 4.5mg 14.10.2020 Quetiapine 4.25mg 17.10.2020 Quetiapine 4mg 21.10.2020 Quetiapine 3.75mg 24.10.2020 Quetiapine 3.5mg 1.11.2020 Quetiapine 3 mg 7.11.2020 Quetiapine 2.5 mgs 13.11.2020 Quetiapine 2 mg 16.11.2020 Quetiapine 1.5 mg 20.11.2020 Quetiapine 1.25mg 23.11.2020 Quetiapine 1mg 26.12.2020 Quetiapine 0.75mg 16.01.2020 Quetiapine 0.5mg 17.02.2020 Quetiapine 0.25mg

Link to post

Well done on your taper! 

April 2019 ct from Clonazepan (Klonopin) 0.5mg. Chaotic CT

Gabapentin November 2019 600mg Chaotic RT

Nozinan November 2019. RT

ct Gabapentin and Nozinan May 2020

Seroquel in July 2020 90mg. Reduced to 50mg in Feb 2020 over one month. Too fast!!

Lexapro July 2020 5mg

Propranolol to control Tachycardia 2020. 15mg given in December 2020 on Cardiologist recommendation. 

 

Link to post
  • 2 weeks later...
senseless
On 2/2/2021 at 12:52 AM, Cat416 said:

Well done on your taper! 

 

Thankyou cat :)

6.01.20 - 6.02.20: Seroquel/Quetiapine 25mg

7.02.20 - 13.02.20: Attempted CT ran into extreme rebound insomnia

13.02.20 - 04.07.20Reinstated and holding Seroquel/Quetiapine 13.5mg, 1mg Circadin 

Began Tapering of Seroquel

04.07.20 - Quetiapine 13mg 12.07.20 - Quetiapine 12.5mg 20.07.20 - Quetiapine 12mg 28.07.20 - Quetiapine 11.5mg

02.08.20 - Quetiapine 11.mg 06.08.20 - Quetiapine 10.5mg 10.08.20 - Quetiapine 10mg 15.08.20 Quetiapine 9.5mg

18.08.20 Quetiapine 9mg 23.08.20 Quetiapine 8.527.08.20 Quetiapine 8mg 31.08.20 Quetiapine 7.75mg02.09.20 Quetiapine 7.5mg 06.09.20 Quetiapine 7.25mg 08.09.20 Quetiapine 7mg 12.09.20 Quetiapine 6.75mg 14.09.20 Quetiapine 6.5mg 19.09.20 Quetiapine 6.25mg 21.09.20 Quetiapine 6mg 24.09.20 Quetiapine 5.75mg 01.10.20 Quetiapine 5.5mg 03.10.20 Quetiapine 5.25mg 05.10.2020 Quetiapine 5mg 09.10.2020 Quetiapine 4.75mg 12.10.2020 Quetiapine 4.5mg 14.10.2020 Quetiapine 4.25mg 17.10.2020 Quetiapine 4mg 21.10.2020 Quetiapine 3.75mg 24.10.2020 Quetiapine 3.5mg 1.11.2020 Quetiapine 3 mg 7.11.2020 Quetiapine 2.5 mgs 13.11.2020 Quetiapine 2 mg 16.11.2020 Quetiapine 1.5 mg 20.11.2020 Quetiapine 1.25mg 23.11.2020 Quetiapine 1mg 26.12.2020 Quetiapine 0.75mg 16.01.2020 Quetiapine 0.5mg 17.02.2020 Quetiapine 0.25mg

Link to post
senseless

Quick update.

Sleep is returning to a normal level now around 7-8 hours now, which is good.

I'm not sure how much longer I should hold at this dose, I'm thinking at least another week  or two may necessary so I have a good base before I jump down. 

Input from @DataGuy and @Shep would be appreciated :) 

One interesting note is recently I have purchased a dreem headband, it is a sleep device that monitors and analyses your sleep via  EEG electrodes, accelerometer and pulse oximeter.
Its shown to be as accurate as conventional polysomnography.

Anyway according to this device most nights I am getting between 3 - 5 hours of rem sleep. Which is incredibly high, most healthy adults get around 90 minutes per night.

I'm thinking surely this must be a consequence of withdrawal? And most likely explains why myself and many others experience high number of awakenings. 

As it has been shown that daily mild stress results in an increase in rapid-eye-movement (REM) sleep https://www.sciencedaily.com/releases/2019/01/190128101104.htm#:~:text=2-,Stress and dream sleep are linked to,brain cell death and survival&text=Summary%3A,sleep%2C a new study reports.

Anyway just thought that was interesting. Going to keep soldiering on :)

6.01.20 - 6.02.20: Seroquel/Quetiapine 25mg

7.02.20 - 13.02.20: Attempted CT ran into extreme rebound insomnia

13.02.20 - 04.07.20Reinstated and holding Seroquel/Quetiapine 13.5mg, 1mg Circadin 

Began Tapering of Seroquel

04.07.20 - Quetiapine 13mg 12.07.20 - Quetiapine 12.5mg 20.07.20 - Quetiapine 12mg 28.07.20 - Quetiapine 11.5mg

02.08.20 - Quetiapine 11.mg 06.08.20 - Quetiapine 10.5mg 10.08.20 - Quetiapine 10mg 15.08.20 Quetiapine 9.5mg

18.08.20 Quetiapine 9mg 23.08.20 Quetiapine 8.527.08.20 Quetiapine 8mg 31.08.20 Quetiapine 7.75mg02.09.20 Quetiapine 7.5mg 06.09.20 Quetiapine 7.25mg 08.09.20 Quetiapine 7mg 12.09.20 Quetiapine 6.75mg 14.09.20 Quetiapine 6.5mg 19.09.20 Quetiapine 6.25mg 21.09.20 Quetiapine 6mg 24.09.20 Quetiapine 5.75mg 01.10.20 Quetiapine 5.5mg 03.10.20 Quetiapine 5.25mg 05.10.2020 Quetiapine 5mg 09.10.2020 Quetiapine 4.75mg 12.10.2020 Quetiapine 4.5mg 14.10.2020 Quetiapine 4.25mg 17.10.2020 Quetiapine 4mg 21.10.2020 Quetiapine 3.75mg 24.10.2020 Quetiapine 3.5mg 1.11.2020 Quetiapine 3 mg 7.11.2020 Quetiapine 2.5 mgs 13.11.2020 Quetiapine 2 mg 16.11.2020 Quetiapine 1.5 mg 20.11.2020 Quetiapine 1.25mg 23.11.2020 Quetiapine 1mg 26.12.2020 Quetiapine 0.75mg 16.01.2020 Quetiapine 0.5mg 17.02.2020 Quetiapine 0.25mg

Link to post
  • Moderator

Hi @senseless,

 

Great work on reducing and stabilizing : ). 

 

That sounds like a cool device. I did a quick google and couldn't find any critical reviews that stood out to me. I know some of those sleep devices claim to track sleep stages and don't, but maybe this one actually does. I see they have a publication in the journal "Sleep" on it. Interesting stuff. Most of these psychotropics taken long term do suppress REM sleep, so much longer REM during withdrawal would be in keeping with what you'd expect to see. I remember I had a sleep study a long time ago while taking clonazepam and they said I had zero REM sleep! I am not sure why that didn't ring any alarm bells with them.

 

So to answer your question, yes, people typically get what is called REM rebound in withdrawal. It is just your brain making up for the REM you missed while on the med. Glenmullen notes in one of his books that it can take over a year for REM sleep to return to normal once people stop taking their antidepressants. I am not sure if similar studies have been done on APs. 

 

In terms of holds and reductions, once you get to very low levels you can typically hold for much longer. Brassmonkey recommends holding for 6 weeks or longer once you get near the end. I think the most important part is that you are stable for a comfortable length of time before you make any major reductions. 

 

Hope you continue to have a smooth ride down!

Remeron - 2004-2005 (bad withdrawal)

Clonazepam - 2005-2018 (jumped around March)

Olanzapine - 2014- late 2017

Domperidone - 2008-2018

Many drugs in between including Lexapro, other benzos and z-drugs.

Still suffering post-withdrawal from Clonazepam (Klonopin), Olanzapine and Domperidone. 

Link to post
  • 2 weeks later...
senseless
On 2/12/2021 at 8:56 PM, DataGuy said:

In terms of holds and reductions, once you get to very low levels you can typically hold for much longer. Brassmonkey recommends holding for 6 weeks or longer once you get near the end. I think the most important part is that you are stable for a comfortable length of time before you make any major reductions. 

 

Hope you continue to have a smooth ride down!


Yeah I understand that in the end game I need to do longer holds, as it more likely to result in successful outcome shown by this site.  But at the same time AP's are probably the most destructive class of drug you can take, so every extra day on this drug means more damage incurred. 

So I'm constantly feeling conflicted about what is the right course of action, as its a balancing act between these two factors.

6.01.20 - 6.02.20: Seroquel/Quetiapine 25mg

7.02.20 - 13.02.20: Attempted CT ran into extreme rebound insomnia

13.02.20 - 04.07.20Reinstated and holding Seroquel/Quetiapine 13.5mg, 1mg Circadin 

Began Tapering of Seroquel

04.07.20 - Quetiapine 13mg 12.07.20 - Quetiapine 12.5mg 20.07.20 - Quetiapine 12mg 28.07.20 - Quetiapine 11.5mg

02.08.20 - Quetiapine 11.mg 06.08.20 - Quetiapine 10.5mg 10.08.20 - Quetiapine 10mg 15.08.20 Quetiapine 9.5mg

18.08.20 Quetiapine 9mg 23.08.20 Quetiapine 8.527.08.20 Quetiapine 8mg 31.08.20 Quetiapine 7.75mg02.09.20 Quetiapine 7.5mg 06.09.20 Quetiapine 7.25mg 08.09.20 Quetiapine 7mg 12.09.20 Quetiapine 6.75mg 14.09.20 Quetiapine 6.5mg 19.09.20 Quetiapine 6.25mg 21.09.20 Quetiapine 6mg 24.09.20 Quetiapine 5.75mg 01.10.20 Quetiapine 5.5mg 03.10.20 Quetiapine 5.25mg 05.10.2020 Quetiapine 5mg 09.10.2020 Quetiapine 4.75mg 12.10.2020 Quetiapine 4.5mg 14.10.2020 Quetiapine 4.25mg 17.10.2020 Quetiapine 4mg 21.10.2020 Quetiapine 3.75mg 24.10.2020 Quetiapine 3.5mg 1.11.2020 Quetiapine 3 mg 7.11.2020 Quetiapine 2.5 mgs 13.11.2020 Quetiapine 2 mg 16.11.2020 Quetiapine 1.5 mg 20.11.2020 Quetiapine 1.25mg 23.11.2020 Quetiapine 1mg 26.12.2020 Quetiapine 0.75mg 16.01.2020 Quetiapine 0.5mg 17.02.2020 Quetiapine 0.25mg

Link to post
senseless

Hello update time,

Dropped to 0.25mg last week. Its going well so far, sleep is about 7-8 hours even had a nice 7 hours consolidated sleep couple days ago.

Hoping not to be hit by delayed withdrawals :)

If my sleep maintains at this level for the next week, i'm gonna jump down to 0.125mg.

6.01.20 - 6.02.20: Seroquel/Quetiapine 25mg

7.02.20 - 13.02.20: Attempted CT ran into extreme rebound insomnia

13.02.20 - 04.07.20Reinstated and holding Seroquel/Quetiapine 13.5mg, 1mg Circadin 

Began Tapering of Seroquel

04.07.20 - Quetiapine 13mg 12.07.20 - Quetiapine 12.5mg 20.07.20 - Quetiapine 12mg 28.07.20 - Quetiapine 11.5mg

02.08.20 - Quetiapine 11.mg 06.08.20 - Quetiapine 10.5mg 10.08.20 - Quetiapine 10mg 15.08.20 Quetiapine 9.5mg

18.08.20 Quetiapine 9mg 23.08.20 Quetiapine 8.527.08.20 Quetiapine 8mg 31.08.20 Quetiapine 7.75mg02.09.20 Quetiapine 7.5mg 06.09.20 Quetiapine 7.25mg 08.09.20 Quetiapine 7mg 12.09.20 Quetiapine 6.75mg 14.09.20 Quetiapine 6.5mg 19.09.20 Quetiapine 6.25mg 21.09.20 Quetiapine 6mg 24.09.20 Quetiapine 5.75mg 01.10.20 Quetiapine 5.5mg 03.10.20 Quetiapine 5.25mg 05.10.2020 Quetiapine 5mg 09.10.2020 Quetiapine 4.75mg 12.10.2020 Quetiapine 4.5mg 14.10.2020 Quetiapine 4.25mg 17.10.2020 Quetiapine 4mg 21.10.2020 Quetiapine 3.75mg 24.10.2020 Quetiapine 3.5mg 1.11.2020 Quetiapine 3 mg 7.11.2020 Quetiapine 2.5 mgs 13.11.2020 Quetiapine 2 mg 16.11.2020 Quetiapine 1.5 mg 20.11.2020 Quetiapine 1.25mg 23.11.2020 Quetiapine 1mg 26.12.2020 Quetiapine 0.75mg 16.01.2020 Quetiapine 0.5mg 17.02.2020 Quetiapine 0.25mg

Link to post

Following your progress. Well done on your progress thus far. I have 50mg to go. I recently made a big cut which I regret. My sleep is very poor. You mention waiting for sleep to recover before continuing to cut. Can you tell me something about that? Do I wait until 8 hours of sleep returns? I may have to wait a long time. My psych wants to give me me Trazzadone for sleep. I don’t want to add any more drugs. Any encouragement? 

April 2019 ct from Clonazepan (Klonopin) 0.5mg. Chaotic CT

Gabapentin November 2019 600mg Chaotic RT

Nozinan November 2019. RT

ct Gabapentin and Nozinan May 2020

Seroquel in July 2020 90mg. Reduced to 50mg in Feb 2020 over one month. Too fast!!

Lexapro July 2020 5mg

Propranolol to control Tachycardia 2020. 15mg given in December 2020 on Cardiologist recommendation. 

 

Link to post

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now

×
×
  • Create New...

Important Information

Terms of Use Privacy Policy