Jump to content
SurvivingAntidepressants.org will be closed to new registrations November 1st through December 31, 2023 ×

Opbroek, 2002 Emotional blunting associated with SSRI-induced sexual dysfunction. Do SSRIs inhibit emotional responses?


Recommended Posts

  • Administrator

Reduced quality of life is an issue with antidepressant treatment.


Int J Neuropsychopharmacol. 2002 Jun;5(2):147-51.

Emotional blunting associated with SSRI-induced sexual dysfunction. Do SSRIs inhibit emotional responses?

Opbroek A, Delgado PL, Laukes C, McGahuey C, Katsanis J, Moreno FA, Manber R.




Department of Psychiatry, University of Arizona Health Sciences Center, USA.


Abstract at http://www.ncbi.nlm.nih.gov/pubmed/12135539 Full text http://www.toxicpsychiatry.com/storage/Antidep%20SSRI%20emotional%20Blunting%202002%20Opbroek.pdf


Anecdotal and published case reports suggest that some patients taking selective serotonin reuptake inhibitors (SSRI) experience diminution in emotional responsiveness. This study aims to define the individual components of emotion disturbed in these patients. Fifteen patients reporting SSRI-induced sexual dysfunction completed the Laukes Emotional Intensity Scale (LEIS), a questionnaire about various emotions. Compared to controls, patients reported significantly (p<0.05) less ability to cry, irritation, care about others' feelings, sadness, erotic dreaming, creativity, surprise, anger, expression of their feelings, worry over things or situations, sexual pleasure, and interest in sex. Total score on the LEIS did not correlate with total score on the Hamilton Depression Rating Scale. In our sample, 80% of patients with SSRI-induced sexual dysfunction also describe clinically significant blunting of several emotions. Emotional blunting may be an under-appreciated side-effect of SSRIs that may contribute to treatment non-compliance and/or reduced quality of life.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

Link to comment
Share on other sites

  • Create New...

Important Information

Terms of Use Privacy Policy