RachelCE Posted October 2, 2020 Share Posted October 2, 2020 I have been on 50mg a day Sertraline for over 3 years. Recently it suddenly stopped working and I have been experiencing withdrawal symptoms despite still taking the dose. I increased the dose by 25mg a day, 2 weeks ago. It hasn't helped much but I'll give it time. I am cutting pills in half so concerned about accuracy. I would like to start tapering off slowly to come off altogether. I want to investigate crushing and dissolving in water to taper slowly. Any advice appreciated. Link to comment
Moderator Emeritus Gridley Posted October 2, 2020 Moderator Emeritus Share Posted October 2, 2020 Welcome to SA, RachelCE. To give members the best information, we ask them to summarize their medication history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly. Account Settings – Create or Edit a signature. What you are experiencing is known as tachyphylaxis or "poop-out" and it is quite common. Tachyphylaxis, Reaching Tolerance or as It's Lovingly Known “Poop-Out” Cutting pills can be inaccurate, as you mentioned. While you're on the increased dose, you might want to consider getting a digital scale. Many members use the Gemini-20 scale, available on Amazon. The GEMINI-20 Scale To taper off the drug, we recommend tapering no more than 10% of your current dose every four weeks. Why taper by 10% of my dosage? This link is specifically about tapering Sertraline and includes instructions for making your own liquid as well as other methods of tapering. Tips for tapering off sertraline (Zoloft) We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. Magnesium, nature's calcium channel blocker Omega-3 fatty acids (fish oil) Add in one at a time and at a low dose in case you do experience problems. This is your Introduction topic, where you can ask questions and connect with other members. We're glad you found your way here. Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of Feb. 22: 7.6mg Taper is 90% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, anti-candida, iron, serrapeptase, nattokinase I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs. Link to comment
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