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Holdontohope: short term Lexapro reaction


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Hello all,

Several months ago I was brought to the ER for bad vertigo, nausea, and vomiting. Had a pretty traumatic experience in the hospital room when I was gave an anti nausea med. I had extreme akathesia towards the point when I needed to escape!! The doc said all of the results came back fine....  the next day I had panic attacks due to the experience. Contacted another doc and told him that I used lexapro like 12 years ago and it helped panic. He prescribed me Lexapro. The next 2 months on Lexapro was crazy. Depression, increased panic attacks, GI issues, DP/DR, and the lost goes on. I continued taking them for the weeks because I was told it can be worse before it's better. After those 2 months, I did a quick taper in about a week. I was only on 5mg. I've been completely off Lexapro for about 3 weeks, and I am still having these symptoms but they've kinda morphed. These past few weeks I've been having extreme intrusive thoughts, and some paranoia. I've been thinking "what if I am the only person who is alive, and everyone else is basically just a robot". I question whether my family is truly alive, and can really feel me...  Those thoughts lead to this feeling of hopelessness... Ive never had these feelings before.

I am thinking that Lexapro changed there ingredients, because I didn't have these issues years ago... I feel like there have been some windows, but i am still scared.... would appreciate some input.




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  • ChessieCat changed the title to Holdontohope: short term Lexapro reaction
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Welcome to SA, Holdontohope.  I'm sorry you're going through this.


To give members the best information, we ask them to summarize their medication history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.  Please include any other psychiatric drugs you've taken since Lexapro 12 years ago, including dates and doses and the dosage you were given recently. Also include whether the Lexapro were on in the past and the more recent Lexapro were brand name or generic.  You'll need to use a computer rather than a phone.


Account Settings – Create or Edit a signature.


You had an adverse reaction to the Lexapro, which means that the drug is poison to your system.  Once you've completed your drug signature, we might be better able to understand why you tolerated Lexapro before but can't tolerate it now.  There are many things we don't understand about the brain and the effect of the powerful drugs on it, but one simple explanation is that your current brain and central nervous system has changed over time, as all of ours do, and what once was tolerated is now rejected by your system.


Do you have any idea what brought you to the ER with vertigo and nausea?


The symptoms of an adverse reaction are very similar to those of withdrawal, and the symptoms you describe are typical of adverse reaction/withdrawal.


Daily Checklist of Antidepressant Withdrawal Symptoms (PDF) 


It's a very encouraging sign that you are experiencing windows, which is a sign of healing.  You will recover and heal, but unfortunately there is no way to predict how long this will take.


The Windows and Waves Pattern of Stabilization


This link illustrates the healing process really well.


Video:  Healing From Antidepressants - Patterns of Recovery


We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 


Magnesium, nature's calcium channel blocker 


Omega-3 fatty acids (fish oil) 


Add in one at a time and at a low dose in case you do experience problems.


This is your Introduction topic, where you can complete your drug signature, ask questions and connect with other members.  We're glad you found your way here.












Gridley Introduction


Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.


Lorazepam 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020 Begin 6-week Ativan-Valium crossover.


Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 15mg.  Aug 2016, discovered SA, updosed to 25mg and holding.  Taper is 66% complete.  


Supplements: omega, vitamins E and D3, magnesium glycinate, probiotic, melatonin .3mg

I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

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