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TigerLily13: beginning my taper

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I was forced on to medications when I was hospitalized for postpartum depression and anxiety and I was put on some of apparently the worst medications to get off of. I am currently taking 75mg Effexor XR, 5mg 3x of Buspar, and 100mg of Trazadone. I am feeling incredibly anxious about about tapering. Right now my plan is to start tapering the Effexor first, then Buspar, then Trazadone. I am really having a hard time thinking about being on all these medications for so long to do a slow taper. Is it possible to taper multiple drugs at the same time? Does anyone have encouraging stories about getting off of these drugs? What are the rates of withdrawal symptoms doing the 10% method? How do you ultimately end the 10% method?

Edited by Gridley

October 2020 Put on Effexor 75mg, Buspar 5mg 3x, Trazadone 100mg

Working on preparing to taper

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Welcome to SA, TigerLily13. I'm very glad you came here first before beginning your taper.


To give members the best information, we ask them to summarize their medication history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.


Account Settings – Create or Edit a signature.


We don't advise tapering multiple drugs at the same time.  If you do and problems arise, there's no way to know the cause.  I sympathize with your concern about being on these drugs for the time necessary for a slow, one-at-a-time taper.  I just finished a 4-year Lexapro taper and have two more drugs to go.  However, we have found that one-at-a-time is the safest, most effective way to taper polydrugs.


The order you plan to taper the drugs--Effexor first, Buspar next, then Trazodone--is what we would recommend.  We recommend tapering the more activating drugs, known as accelerators, first, leaving the more sedating drugs, known as brakes, in place to preserve sleep to be tapered laters. SNRI's like Effexor are accelerators.  Buspar and Trazodone are both brakes but Trazodone is more sedating.


Taking multiple psych drugs? Which drug to taper first?


As you know, re commend tapering by no more than 10% of current dose every four weeks.  There's no way to predict the amount of withdrawal symptoms using this method.  As the link explains, this is a median harm-reduction approach than will minimize withdrawal symptoms for the majority of people.  Some people can taper faster and some have to taper more slowly.  The link explains how you can, after an initial couple of months at 10%, try to go a bit faster to see if you can tolerate it.


Why taper by 10% of my dosage?


This link is specifically about tapering Effexor and explains the method of removing beads to taper by 10%.


Tips for tapering off venlafaxine (Effexor)


2 hours ago, TigerLily13 said:

Does anyone have encouraging stories about getting off of these drugs?


Look at the stories in our Success Stories forum on our main page.  You can also Google SurvivingAntidepressants.org effexor success stories


2 hours ago, TigerLily13 said:

How do you ultimately end the 10% method?


With Effexor and bead counting, you'd likely get down to one bead, hold for several weeks, then jump to zero (stop).  With other drugs, we recommend getting down into the 0.00's (like 0.05mg or 0.025mg before jumping.


We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 




Add in one at a time and at a low dose in case you do experience problems. Get supplements that are single ingredient (not mixed with other types of supplements).


This is your Introduction topic, where you can complete your drug signature, ask questions and connect with other members.  We're glad you found your way here.









Gridley Introduction


Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.


Lorazepam 1 mg 1986-1991 CT, resumed a few months later. CT 2000.  1 mg 2011-2016.  Sept, 2016 increased to 0.5 X 3 in split dose. Sept. 2019 increased to 0.625 X 3 after crossover to new brand


Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 15mg.  Aug 2016, discovered SA, updosed to 25mg and holding.  Taper is 66% complete.  


Supplements: omega, vitamins E and D3, magnesium glycinate, probiotic, melatonin .3mg

I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

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