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twitch22: is this withdrawal?


twitch22

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Hello everyone,

I was on Mirtazapine for about 3 years - 15 mg. I had a stressful time going on and decided to up to 30 mg. I then a few weeks later started suffering from a lump in throat/tight throat feeling, muscle tension in neck, twitching all over body, insomnia. I talked it over with my Psych Doc and we decided to go back down to 15 mg, the twitching is still there, but its not as bad. I still suffered from the lump in the throat feeling, though. I was then precribed 10mg of Lexapro and quickly went up to 20mg within a few weeks on top of Trazadone for sleep. After weeks of being on all of those three meds, I was still suffering the terrible neck tension and lump in throat. I decided to taper of Mirtazapine, and after about 6 months off of that, still going through the same symptoms. So I then decided to get off the Lexapro. I have been off of Lexapro for a little over 60 days now. Still, this terrible lump in throat/anxiety/depression feeling is still taking over my life. The only thing I am on now is Trazadone for sleep (I desperately need that to sleep). I feel like I am not able to enjoy anything anymore, it feels like a switch flipped in my head, some sort of reaction, after going to 30 mg of Mirtazapine and it wont switch back. I have looked up a lot of my symptoms and they sound like withdrawal.... could Mirtazapine messed up my brain for life? its been like 2 years since I started feeling these symptoms. I am hopeless right now. I don't know if I will ever feel better. My Doc thinks I should try Buspirone, but my problem is.... if Mirt and Lexapro didn't work together, should I try another drug? or just be patient and wait this out? Thanks everyone

Edited by Shep
added new username to title

2015 - Mirtazapine 15mg for 3 years

2018 - bump up to 30mg Mirtazipine because I was depressed after taking Adderall , two weeks later adverse reaction

later 2018 - jumped right back into 15mg

Early 2019 - prescribed Baclofen 10 mg, Lexapro 10 mg, Requip 2mg, and Trazadone 100mg on top of my Mirtazapine. Upped to Lexapro 20 mg a few weeks later.

Mid 2019 - still having symptoms, start taper off Mirtazapine (took about 3 or 4 months to come off)

later 2019 - still having symptoms after coming off Mirt for many months, start taper off requip.

early 2020 - off requip, taper baclofen

mid 2020 - start taper off Lexapro.

September 30th, 2020 - off Lexapro 

Current Medications - 50 mg Trazadone

 

 

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  • ChessieCat changed the title to REAL NAME?: is this withdrawal?
  • Shep changed the title to twitch22: is this withdrawal?
  • Moderator

Welcome to SA, twitch22.

 

To give members the best information, we ask them to summarize their medication history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.

 

Account Settings – Create or Edit a signature.

 

You should be aware, in case your doctor is not, that the three drugs you were on previously at the same time, mirtazapine, Lexapro and Trazodone, have major interactions for serotonin syndrome.  You can check them out for yourself using this link:

 

Drug Interactions Checker 

 

Your doctor may also not be aware that there is a major serotonin syndrome drug interaction between Trazodone and the new drug he/she suggested, Buspirone.  Our recommendation would be not to start the Buspirone or another drug.  We are a site or going off drugs, and do not make adding yet another drug to your system.  

 

It sounds like you had an adverse reaction to the increased 30mg of Mirtazapine.  The symptoms of an adverse reaction are very similar to those of withdrawal, and the symptoms you describe are typical. You are likely also suffering from withdrawal from a too-fast taper of Lexapro.  Not being able to enjoy anything, known as anhedonia, is a typical withdrawal symptom.  Your brain is not damaged permanently.  It will heal over tie and the symptoms will fade.  Your situation is by no means hopeless.  To repeat, you will heal and you will feel better.  You just need to give it time.  Be patient and wait it out.

 

So that you have a better idea of what you're experiencing, here is some information on withdrawal and the healing process.

 

 

 

 

When we take psychiatric medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur.  

 

These explain the healing process really well.

 

 

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

 

 

Add in one at a time and at a low dose in case you do experience problems. Get supplements that are single ingredient (not mixed with other types of supplements).

 

This is your Introduction topic, where you can complete your drug signature, ask questions and connect with other members.  We're glad you found your way here.

 

 

 

 

 

 
Edited by Gridley

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020, 7-week Ativan-Valium crossover + change to one 18.75mg dose, w/1 month hold.

Feb. 9, 2021, begin 10% every 4 weeks taper.  Current dose as of Feb. 23: 16.0mgai.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 16mgai (0.44mgpw).  Aug 2016, discovered SA, holding at 16mg.  Taper is 78% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg.


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

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Hi Gridley. Hope you are doing well. I’ll post my history right here because it didn’t allow me to fit it all in my signature:

 

2015 - Mirtazapine 15mg for 3 years

early 2018 - did Adderall for one day, maybe took too much

2018 - bump up to 30mg Mirtazipine because I was depressed after taking Adderall , two weeks later adverse reaction

later 2018 - jumped right back into 15mg Mirt, no taper, still having symptoms 

early 2019 - went to Vegas, did Cocaine once, realize I didn’t want to get into hard drugs, went to rehab, still having symptoms 

Early 2019 - prescribed Baclofen 10 mg, Lexapro 10 mg, Requip 2mg, and Trazadone 100mg on top of my Mirtazapine. Upped to Lexapro 20 mg a few weeks later.

Mid 2019 - still having symptoms, start taper off Mirtazapine (took about 3 or 4 months to come off)

later 2019 - still having symptoms after coming off Mirt for many months, start taper off requip.

early 2020 - off requip, still having symptoms, start taper off baclofen.

mid 2020 - still having symptoms, start taper off Lexapro.

September 30th, 2020 - off Lexapro 

Current Medications - 50 mg Trazadone at night

 

please give me advice on how to fit this all in my signature lol. 

2015 - Mirtazapine 15mg for 3 years

2018 - bump up to 30mg Mirtazipine because I was depressed after taking Adderall , two weeks later adverse reaction

later 2018 - jumped right back into 15mg

Early 2019 - prescribed Baclofen 10 mg, Lexapro 10 mg, Requip 2mg, and Trazadone 100mg on top of my Mirtazapine. Upped to Lexapro 20 mg a few weeks later.

Mid 2019 - still having symptoms, start taper off Mirtazapine (took about 3 or 4 months to come off)

later 2019 - still having symptoms after coming off Mirt for many months, start taper off requip.

early 2020 - off requip, taper baclofen

mid 2020 - start taper off Lexapro.

September 30th, 2020 - off Lexapro 

Current Medications - 50 mg Trazadone

 

 

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  • Moderator
28 minutes ago, twitch22 said:

please give me advice on how to fit this all in my signature lol. 

I think the maximum is 12 lines.  If you'll omit the 2nd line about Adderall, you should be at 12.  Here's the link:  

 

 

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020, 7-week Ativan-Valium crossover + change to one 18.75mg dose, w/1 month hold.

Feb. 9, 2021, begin 10% every 4 weeks taper.  Current dose as of Feb. 23: 16.0mgai.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 16mgai (0.44mgpw).  Aug 2016, discovered SA, holding at 16mg.  Taper is 78% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg.


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

Link to post
  • 3 months later...

Hello all,

 I posted a couple months back: 

I am still having a ton of symptoms that I feel like are not healing. I have been off Mirtazapine for a year and a half and off lexapro for 5 months. My muscles are still twitching, my neck is tense all day, my throat is tense. I have no interest in things I used to love because I feel like my body is constantly tense. Lately, I have this taste in my mouth, on the sides of my tongue and pressure in the roof of my mouth and teeth. I do not feeling like this is getting better. I’m starting to think I may have messed myself up for good. Here is the full list of symptoms I have been dealing with:

 

muscle twitching, throat tension, neck tension, waking up at 6:30 am every morning, pressure in mouth, weird taste in mouth, acid reflux, exercising worsens symptoms (exercising used to be one of my antidepressants). I’m losing hope. Its been about 2 years since I started feeling some of these symptoms. Sometimes I don’t think it’s withdrawal. How could it last this long? This all started when I was on 15 mg Mirtazapine. I took adderall, about 90mg (bad choice). Next day I was severely depressed and that went on for a few weeks. I then asked my doc to up my Mirt to 30mg and a week later this all started and it hasn’t gone away since. I’m afraid I messed myself up from the adderall. Can one dose do this to you? Or is this definitely an adverse reaction to Mirt? I’m so scared I’ll never be myself again. Thank you for reading.

2015 - Mirtazapine 15mg for 3 years

2018 - bump up to 30mg Mirtazipine because I was depressed after taking Adderall , two weeks later adverse reaction

later 2018 - jumped right back into 15mg

Early 2019 - prescribed Baclofen 10 mg, Lexapro 10 mg, Requip 2mg, and Trazadone 100mg on top of my Mirtazapine. Upped to Lexapro 20 mg a few weeks later.

Mid 2019 - still having symptoms, start taper off Mirtazapine (took about 3 or 4 months to come off)

later 2019 - still having symptoms after coming off Mirt for many months, start taper off requip.

early 2020 - off requip, taper baclofen

mid 2020 - start taper off Lexapro.

September 30th, 2020 - off Lexapro 

Current Medications - 50 mg Trazadone

 

 

Link to post
  • Moderator Emeritus

Here is your Introduction topic:  twitch22-is-this-withdrawal

 

Only 1 Introduction topic per member.  Your Introduction topic is the best place to ask questions specific to your situation and where you can journal your progress.  This way your history is in one place and you will not need to repeat yourself.

 

This topic will be merged with your original Introduction.

 

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

Plodding along inch by inch:  12" = 1',  3' =  36 " or 1 yard,  1760 yards  = 63,360" or 1 mile

Current from 6 Mar 2021:  Pristiq 0.328 mg

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

Link to post
11 hours ago, twitch22 said:

Hello all,

 I posted a couple months back: 

I am still having a ton of symptoms that I feel like are not healing. I have been off Mirtazapine for a year and a half and off lexapro for 5 months. My muscles are still twitching, my neck is tense all day, my throat is tense. I have no interest in things I used to love because I feel like my body is constantly tense. Lately, I have this taste in my mouth, on the sides of my tongue and pressure in the roof of my mouth and teeth. I do not feeling like this is getting better. I’m starting to think I may have messed myself up for good. Here is the full list of symptoms I have been dealing with:

 

muscle twitching, throat tension, neck tension, waking up at 6:30 am every morning, pressure in mouth, weird taste in mouth, acid reflux, exercising worsens symptoms (exercising used to be one of my antidepressants). I’m losing hope. Its been about 2 years since I started feeling some of these symptoms. Sometimes I don’t think it’s withdrawal. How could it last this long? This all started when I was on 15 mg Mirtazapine. I took adderall, about 90mg (bad choice). Next day I was severely depressed and that went on for a few weeks. I then asked my doc to up my Mirt to 30mg and a week later this all started and it hasn’t gone away since. I’m afraid I messed myself up from the adderall. Can one dose do this to you? Or is this definitely an adverse reaction to Mirt? I’m so scared I’ll never be myself again. Thank you for reading.

Your body is trying to calm itself. Let it

March-2017-Dec-2017 ativanCT /reinstated ativan 1mg tapered 2 months/June 2017-April 2018 zyprexa 10mg switched to seroquel 200-300mg in april 2018/dec-2017-present zoloft 100mg/ quit seroquel 200-300mg cold turkey May 6 2018 reinstated seroquel 100mg around May 25 2018 since then tapered to 50mg zoloft and 50 mg of seroquel presently other medications Testosterone cypionate 2oomg every 4 days

UPDATE -August 20 2018--october 20 2018 tapered off Testosterone/Nov 7 2018 --Dec 20 2018 Lamictal micro dose 2.50mg 1 1/2 weeks then reduced to 1.25 then fast tapered as it became paridoxial.nausea- racing thoughts- agitation and insomnia.

August 28 2018 to Present Cannabis indica micro dose PM bedtime only.

Presently Seroquel 37.5 mg bedtime /Zoloft 47mg morning

May 2018-Present Multivitamin/ Bcomplex/Vit C 1000MG/B12 1000MCG/Fish oils 2grams/

Jan 2019-Trace mineral liquid low dose

Update dec 2019 -29mg of zoloft tapering/Seroquel 37.5 holding/1 or 2  ativan 1mg a month as needed if that.

Black seed oil-caprylic acid-/b complex/b12/multi/D/E/melatonin

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