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Camille: Lexapro WD "threshold"from 5mg to 2.5mg?


Camille

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Hello, I need some recommendation for my tapering. Here is my background :)

At 15, i had a massive burn-out and was prescribed antidepressants. I am today 23 and have been on antidepressants almost without interruption. I don't remember all the different antidepressants I was on. I know it did help when i was in emergency situation (extreme anxiety and depression) but it was not satisfactory either, that's why i always had the intention to stop. I quit Effexor once and Brintellix once without a very long taper and didn't feel any major WD symptoms, except that my depression and anxiety (that was already here before) came back, but not worse than it was before. In January 2020, i was prescribed with Lexapro 15mg. After 3 months of use, I decided to taper (in April 2020). Everything was going pretty fine with no any WD symptoms (except a few headaches the first week after a decrease). But in June, when i decreased my dose from 5mg to 2,5 mg, I instantly felt more horrible than I had ever did (so it wasn't a return of my original depression). I wasn't able to do any movements without being out of breath and i felt more anxious and depressed than i had ever been, I could only describe it as "hell"with terrible emotions that i had never felt before, not even close. I waited something like 5 days and I decides to come back to 5mg because it unbearable. Coming back to 5mg wasn't enough to reverse these symptoms so i had to come back on 10mg. 
I want to taper again. I decreased my dose from 10mg to 7,5mg in September without any major symptoms. I've been stable ever since (we are now in December so i want to decrease my dose again to 6mg. The thing is I dont understand why in my last experience, i had no symptoms whatsoever until I decrease from 5mg to 2,5mg and I dont know how to avoid that from happening again. Is there like some sort of a "threshold dose" where everything goes bad if you go below it ? I'm feeling fine right now but i know how fast everything can go real bad.

Thanks in advance for your answer and also thanks for this existence of this website :)

Edited by manymoretodays
moved from S and S care, name added to title
  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

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  • manymoretodays changed the title to Camille: Lexapro WD "threshold"from 5mg to 2,5 mg ?
  • Moderator

Welcome to SA, Camille.

 

To give members the best information, we ask them to summarize their medication history in a signature -- drugs, doses, dates, and discontinuations & reinstatements, in the last 12-24 months particularly.  Your history in 2020 is the most important.  A list format is best.

 

Account Settings – Create or Edit a signature.

 

Lexapro is the strongest SSRI on the market (2 to 4 times as strong as Celexa or Paxil) and the the lower doses of Lexapro (from 10mg down) are the most potent, which (along with the fact that you reduced by 50%) would explain why you got "caught"  with withdrawal when you got down to the very low, very strong doses.  There is no such thing as a threshold dose where everything goes bad if you go below it.  If you taper slowly enough, you will be able to taper down all the way to zero.  I recently completed tapering off 20mg Lexapro after a 4-year taper, jumping to zero at 0.025mg.  

 

Your drop from 5mg to 2.5mg was a 50% drop, five times faster than what we recommend.  That reduction, at the point where Lexapro is very  potent, caused the withdrawal symptoms you experienced.  We recommend tapering no more than 10% of your current dose every four weeks.

 

Why taper by 10% of my dosage?

 

This link is specifically about tapering Lexapro, including how to get the nonstandard doses needed for a 10% taper.

 

Tips for tapering off escitalopram (Lexapro)

 

It is too soon to taper again.  You've made many changes in your dosage recently, including a very large reinstatement and a 50% decrease, leaving your system in a sensitized state, and I'd recommend you stabilize where you are at 7.5mg for at least three months before tapering again.  Withdrawal symptoms can be delayed, and you would be well-served by a hold at this point.  Decreasing from 10mg to 7.5mg was a 25% decrease, and withdrawal symptoms can be delayed.  Deceasing from 7.5mg to 6mg is a 20% decrease, twice what we recommend.  After your hold I recommend you taper by no more than 10% of your current dose.  

 

So that you have a better idea of withdrawal and the healing process, here are some helpful links:

 

 

 

When we take psychiatric medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur.  

 

These explain the healing process really well.

 

 

 

We don't recommend a lot of supplements on SA, as many members report being sensitive to them due to our over-reactive nervous systems, but two supplements that we do recommend are magnesium and omega 3 (fish oil). Many people find these to be calming to the nervous system. 

 

 

 

Add in one at a time and at a low dose in case you do experience problems. Get supplements that are single ingredient (not mixed with other types of supplements).

 

This is your Introduction topic, where you can complete your drug signature, ask questions and connect with other members.  We're glad you found your way here.

 

 

 

 

 

 

 

 

 

 
Edited by Gridley

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020, 7-week Ativan-Valium crossover + change to one 18.75mg dose, w/1 month hold.

Feb. 9, 2021, begin 10% every 4 weeks taper.  Current dose as of Feb. 23: 16.0mgai.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 16mgai (0.44mgpw).  Aug 2016, discovered SA, holding at 16mg.  Taper is 78% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg.


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

Link to post
  • ChessieCat changed the title to Camille: Lexapro WD "threshold"from 5mg to 2.5mg?
  • 3 weeks later...

Thanks Gridley for your reply !

I see that you have successfully tapered Lexapro. Did you use the liquid version to do so or a pill cutter? I tried the liquid version last time, taking 10 drops (for 10mg) and it didn't have any effects, it was like i didn't take the med (I had my usual headache that i have when i forget to take my med) so i had to take my usual pill. Is it possible that the liquid version would not work on me or was it just this one product that was defective? Also I'm worried that when I cut pill into very small bits, it might loose its effect because of some digestion process that would just make the micro pill ineffective? Am i being crazy to think that or is it possible that pills loose its effect when cut too small? 

 

  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

Link to post
  • Moderator
3 hours ago, Camille said:

a pill cutter?

I used a digital scale and weighed powdered tablets crushed between two spoons.  I added/subtracted powder as needed to get my dose using a little spoon available on Amazon.

 

3 hours ago, Camille said:

the liquid version would not work on me

The liquid version does not work for some people.

3 hours ago, Camille said:

Also I'm worried that when I cut pill into very small bits, it might loose its effect because of some digestion process that would just make the micro pill ineffective? Am i being crazy to think that or is it possible that pills loose its effect when cut too small? 

Crushing pills to powder is a well-established method for tapering, and I've never heard of this as a problem.  

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020, 7-week Ativan-Valium crossover + change to one 18.75mg dose, w/1 month hold.

Feb. 9, 2021, begin 10% every 4 weeks taper.  Current dose as of Feb. 23: 16.0mgai.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 16mgai (0.44mgpw).  Aug 2016, discovered SA, holding at 16mg.  Taper is 78% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg.


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

Link to post

Ok Gridley thanks a lot, I'm reassured 😊

  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

Link to post
53 minutes ago, Gridley said:

I used a digital scale and weighed powdered tablets crushed between two spoons.  I added/subtracted powder as needed to get my dose using a little spoon available on Amazon.

What was the brand of the digital scale you used ? Was it accurate up to the tenth of a miligram ? 🤫

  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

Link to post
  • Moderator
9 minutes ago, Camille said:

What was the brand of the digital scale you used ? Was it accurate up to the tenth of a miligram ? 🤫

I used (and still use) the Gemini-20 scale available on Amazon.  By using the 10 gram weight that comes with the scale, I found it accurate to 1mg pill weight.  Because there's so much more pill weight (because of fillers and binders) than active ingredient (dosage), I was able to to measure to around 0.5mg or less active ingredient   

 

Others have found the scale accurate to only 4mg pill weight, after which they had to "eyeball" their measurement by dividing it manually.

Gridley Introduction

 

Lexapro 20 mg since 2004.  Begin Brassmonkey Slide Taper Jan. 2017.   

End 2017 year 1 of taper at 9.25mg 

End 2018 year 2 of taper at 4.1mg

End 2019 year 3 of taper at 1.0mg  

Oct. 30, 2020  Jump to zero from 0.025mg.  Current dose: 0.000mg

3 year, 10 month taper is 100% complete.

 

Ativan 1 mg 1986-1991 CT, soon reinstated.  CT 2000. RI 1 mg 2011-2016.  Sept. 2016  0.625mg X 3

Nov.27, 2020, 7-week Ativan-Valium crossover + change to one 18.75mg dose, w/1 month hold.

Feb. 9, 2021, begin 10% every 4 weeks taper.  Current dose as of Feb. 23: 16.0mgai.

 

Imipramine 75 mg daily since 1986.  Jan. 2016 began every 3-weeks 10% taper, down to 16mgai (0.44mgpw).  Aug 2016, discovered SA, holding at 16mg.  Taper is 78% complete.  

  

Supplements: omega, vitamins C, E and D3, magnesium glycinate, probiotic, zinc, melatonin .3mg.


I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.

Link to post
  • 3 weeks later...

Hello everyone !

I'm taking 10mg in pill and i want to start taking it in water to prepare for my future taper (I'm planning on using the titration method), so by dissolving my pill in a glass of water and of course making sure that i rinse and drink the entirety of the dissolved pill. I was wondering if anyone has reported that dissolving Lexapro pill in water could alter/reduce its efficacy ? Or that most people had no problem with it and didn't notice any major difference in efficacy ? 

Thanks in advance for any reply.

  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

Link to post
  • 4 weeks later...
Yesyes123

@Camille hello! It would probably be better to get the liquid form instead of dissolving the pill. We can talk more about this later - and surely the mods will help too. I plan on switching to liquid too this year so I can start tapering sometime. Peace and healing

July 2015 - Started Escitalopram 10mg (Lexapro) at age 15. Took it everyday until July 2020 (5 Years)

July 2020 - Turned 21 started tapering off until August (TOO FAST TAPER/ ALMOST SAME AS COLD TURKEY)

August 2020 -  Clear Manic episode (nothing absurd or life threatening)

September 2020 - Start feeling a bit weird

October 2020 - Crashed. The absolute worst time of my life. 

Late October 2020 - Reinstated Escitalopram 10mg. Perscribed Antipsychotics (Lithium, Seroquel) REFUSED

Early November 2020 - Psychiatrist wrongly upped the dosage to 15mg. Still taking 15mg / day as of today. 

 

22 January 2021: 

Beginning to stabilize on 15mg/day Escitalopram (Lexapro) 🧠

Taking 25mg Magnesium Citrate 4x per day / 2000mg Vitamin C Prolonged Release + Kiwis + Fresh Fruit / Salmon everyday for Omega3 Fatty Acids

Link to post

Hello Yesyes123. I already tried the liquid form bought at the pharmacy and it did not work at all, it was like I did not take my med, I had my classic interdose withdrawal headaches and i had to take my normal solid pill. I tried it twice and both times it didn't work. Sure it could have been this one liquid bottle that was not working but I feel you have more control when you make your own liquid, and I've tried it and it seems to work very well. Right now, I'm at 8,75mg (solid form). I feel ok but still "anhedonic" (if that word exist), that's why i upped my dose. I tried going all the way up to 10mg but I started having insomnia (although my mood was pretty good) so i had to stay at 8,75mg. I think I did too much change on my dose on a short time, now my plan is to not change anything until March. In march, if I still have "anhedonia", ill slowly convert my med into a 100% liquid form (at a speed of 1,25mg/2 weeks) and then I'll analyse the situation again when this is done. But I've come to realize and accept how slow of a process this is and that i have to be extremely careful every time i make a move because the risks are too high and you can't really go back (like I felt great on 10mg last August and when I tried 10mg again in January I had insomnia). I'm also trying Intermittent fasting again (already did it before and it did wonders for my fatigue) because I hear it can help with brain plasticity.

  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

Link to post
Yesyes123

@Camille thanks for your response. When you were switching from pill to liquid, did you do it very slowly? Like one week 3/4 pill + 1/4 liquid, then one week 1/2 pill 1/2 liquid etc ... or how did you make the switch? Also what brand liquid escitalopram did you use? Thanks

July 2015 - Started Escitalopram 10mg (Lexapro) at age 15. Took it everyday until July 2020 (5 Years)

July 2020 - Turned 21 started tapering off until August (TOO FAST TAPER/ ALMOST SAME AS COLD TURKEY)

August 2020 -  Clear Manic episode (nothing absurd or life threatening)

September 2020 - Start feeling a bit weird

October 2020 - Crashed. The absolute worst time of my life. 

Late October 2020 - Reinstated Escitalopram 10mg. Perscribed Antipsychotics (Lithium, Seroquel) REFUSED

Early November 2020 - Psychiatrist wrongly upped the dosage to 15mg. Still taking 15mg / day as of today. 

 

22 January 2021: 

Beginning to stabilize on 15mg/day Escitalopram (Lexapro) 🧠

Taking 25mg Magnesium Citrate 4x per day / 2000mg Vitamin C Prolonged Release + Kiwis + Fresh Fruit / Salmon everyday for Omega3 Fatty Acids

Link to post
Yesyes123

How are you taking 8,75mg? Splitting pills?

July 2015 - Started Escitalopram 10mg (Lexapro) at age 15. Took it everyday until July 2020 (5 Years)

July 2020 - Turned 21 started tapering off until August (TOO FAST TAPER/ ALMOST SAME AS COLD TURKEY)

August 2020 -  Clear Manic episode (nothing absurd or life threatening)

September 2020 - Start feeling a bit weird

October 2020 - Crashed. The absolute worst time of my life. 

Late October 2020 - Reinstated Escitalopram 10mg. Perscribed Antipsychotics (Lithium, Seroquel) REFUSED

Early November 2020 - Psychiatrist wrongly upped the dosage to 15mg. Still taking 15mg / day as of today. 

 

22 January 2021: 

Beginning to stabilize on 15mg/day Escitalopram (Lexapro) 🧠

Taking 25mg Magnesium Citrate 4x per day / 2000mg Vitamin C Prolonged Release + Kiwis + Fresh Fruit / Salmon everyday for Omega3 Fatty Acids

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54 minutes ago, Yesyes123 said:

How are you taking 8,75mg? Splitting pills?

Im cutting a 15mg pill in half (so 7,5mg) and a 5mg in 4 (so 1,25mg). I use a pill cutter to split the 5mg, it's a bit difficult but reasonnably accurate so I'm satisfied with it.

 

2 hours ago, Yesyes123 said:

When you were switching from pill to liquid, did you do it very slowly? Like one week 3/4 pill + 1/4 liquid, then one week 1/2 pill 1/2 liquid etc ... or how did you make the switch?

No, I switched all of a sudden and I should not have done it that fast. Nonetheless, my observation is still accurate : it was very apparent that the liquid form had no effect whatsoever on me. Not doing a transition into liquid, though it can have some kind of noticeable effect on you, is not supposed to result in a total loss of effect of the med. Who knows, maybe it's because I did not shake it enough and all of the "active substance" was at the bottom (don"t know if that's a real thing) or maybe it was not well preserved in the pharmacy, but it really was like taking nothing at all (this I know because i always have the same sensation of headache and dizziness when I'm late taking my med aka "interdose withdawal")

 

2 hours ago, Yesyes123 said:

Also what brand liquid escitalopram did you use?

My pharmacist will occasionally change the brand of the med and I don't mind because it doesn't make any noticeable change on me. Right now, the 7,5mg part of the pill is from a brand called " Biogran" and the 1,25mg part is from "EvoluGEN". The liquid form I tried a couple month ago was "Seroplex" (so the originator brand). By the way, I'm French so all these brands might be only available in France.

  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

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Yesyes123

Thanks for the response - do you feel that probiotics are helping?

July 2015 - Started Escitalopram 10mg (Lexapro) at age 15. Took it everyday until July 2020 (5 Years)

July 2020 - Turned 21 started tapering off until August (TOO FAST TAPER/ ALMOST SAME AS COLD TURKEY)

August 2020 -  Clear Manic episode (nothing absurd or life threatening)

September 2020 - Start feeling a bit weird

October 2020 - Crashed. The absolute worst time of my life. 

Late October 2020 - Reinstated Escitalopram 10mg. Perscribed Antipsychotics (Lithium, Seroquel) REFUSED

Early November 2020 - Psychiatrist wrongly upped the dosage to 15mg. Still taking 15mg / day as of today. 

 

22 January 2021: 

Beginning to stabilize on 15mg/day Escitalopram (Lexapro) 🧠

Taking 25mg Magnesium Citrate 4x per day / 2000mg Vitamin C Prolonged Release + Kiwis + Fresh Fruit / Salmon everyday for Omega3 Fatty Acids

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1 hour ago, Yesyes123 said:

Thanks for the response - do you feel that probiotics are helping?

  Saying they were a miracle to me would be an understatement. I'm convinced that probiotics cured my severe cystic acne (I literally stopped having new pimples after 3 days of use, I know it seems crazy and I really took time to make the link because it seemed crazy to me too) and was the reason I felt so good and happy for the first time in my life last August/beginning of September (some might argue that it may have been the 10mg of ADs starting to have effect but I don't think so because I took this exact same dose back in April 2020 and I did not feel the same way at all).

  Unfortunately, probiotics can't do much against antidepressants withdrawal. Of course, all of these are just observations from my personal experience, but these observations are all backed up by a lot of scientific studies so they're not completely absurd. According to some scientific papers, depression is not a "neurological" disease (except when it's depression that is a consequence of WD from ADs, then it becomes indeed some form of chemical imbalance induced depression), but a disease that is a consequence of an unhealthy gut. Anyway, I want to share this knowledge to other people but at the same time I don't want seem like some kind of crazy preacher for a probiotics cult.

  • 2012 : Started antidepressants, almost without interruption until now. I tried many different sorts (Effexor, Zoloft, Brintellix, Prozac...). Tried stopping multiple times with fast tapers but always ending up back on them again
  • November 2019 Tapered pretty quickly Brintellix, no major WD symptoms but original anxiety and depression came back
  • March 2020: Started LEXAPRO 15mg
  • April 2020: lowered to 10mg Lexapro, no major WD
  • Mai 2020 : 7,5mg then 5mg Lexapro, no major WD
  • June 2020 : lowered to 2,5mg --> major WD 
  • July 2020 : back on Lexapro 10mg and started probiotics which helped a lot (also with acne)
  • September 2020 : BIG MISTAKE of lowering to 7,5mg (so a 25% decrease which is way too much, especially after such a recent bad experience of WD, nervous system didn't have time to repair), anhedonia hits immediately (like right on the day of the decrease)
  • (1 December 2020: Tried the liquid formulation --> doesn't work on me, it's like I didn't take my meds)
  • 5 December 2020 : Decides to up my dose because my mood doesn't seem to improve -->9,375 (by crushing in 2 a 15mg pill (so 7,5mg) and crushing in 4 with a pill cutter a 5mg pill(so 1,25mg) and crushing it in 8 (so 0,625mg) waiting to see how it goes.
  • 5 January 2020 : back on 10mg again--> Bad insomnia although good enough mood 
  • 25 January : Back on 8,75mg, sleep back to normal, anhedonia

Plan for the future : I finally realized how sensitized  my nervous system have become and how slow I have to taper. I plan to stay on 8,75mg until March 1st. If at that date, I still have anhedonia, I'll slowly convert my dose in liquid form (at a speed of 1,25mg/2 weeks). If I start feeling good at any point during this process, I'll stop moving anything for 1 year. After I fully convert to liquid form, the next step would be to slowly decrease my dosage (with the water titration method) at a speed of 0,1mg/month. But I'll only start decreasing when I'm not longer anhedonic and after 1 year of feeling good.

Meds at the moment : 2 probiotics in the morning from "Lactibiane Reference" + 8,75mg Escitalopram 

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