Jump to content

Palmitoylethanolamide (PEA)


Recommended Posts

  • Mentor

I don't find informations about it in the site (but if it's not a right place to post it, please some moderators to move it). I would to ask if someone tried this supplement often prescribed for fibromyalgic pain (that sometimes could be similar to pain induced by WD) and had some benefits.

 

Here some informations (from Wikipedia):

https://en.wikipedia.org/wiki/Palmitoylethanolamide

 

July 2015: the 20mg citalopram for great stress begins

After two years I start tapering (slow but without medical advice) and I guess wrongly. First up to 10 mg, then 5 mg and 2 mg (liquid solution) and skips

January 2020 (I don't remember exactly the day): off citalopram (last dose 2mg).

June 2020: adrenal crash. The beginning of Hell on Earth

 

Current supplement:

- saffron pill (20 mg) + vit. E, omega 3 (EPA + DHA) 2g, magnesium bisglycinate 300 mg, iron , vitamin D3 (2500ui) +K7 (50 ui), vitamin C (1g) + quercitin (25 mg), theanine (as necessary).

 

Try meditating / mindfulness, walking every day, CBT/ACT, massage.

 

"E quindi uscimmo a riveder le stelle" ("And so we went out to see the stars again")

(Dante Alighieri, Divine Comedy , Inferno, XXXIV, 139)

Link to post
Share on other sites
  • 2 weeks later...
  • Mentor

Thank you for your answer, @MNgal1960! Can I ask you if you saw benefits immediatly or if it works on accumulation? Thank you!

July 2015: the 20mg citalopram for great stress begins

After two years I start tapering (slow but without medical advice) and I guess wrongly. First up to 10 mg, then 5 mg and 2 mg (liquid solution) and skips

January 2020 (I don't remember exactly the day): off citalopram (last dose 2mg).

June 2020: adrenal crash. The beginning of Hell on Earth

 

Current supplement:

- saffron pill (20 mg) + vit. E, omega 3 (EPA + DHA) 2g, magnesium bisglycinate 300 mg, iron , vitamin D3 (2500ui) +K7 (50 ui), vitamin C (1g) + quercitin (25 mg), theanine (as necessary).

 

Try meditating / mindfulness, walking every day, CBT/ACT, massage.

 

"E quindi uscimmo a riveder le stelle" ("And so we went out to see the stars again")

(Dante Alighieri, Divine Comedy , Inferno, XXXIV, 139)

Link to post
Share on other sites
MNgal1960

It was over a month before I saw benefits. Also, I took twice what the label said divided into 3 doses/day (one with each meal). 

 

I think the package said to try for 6 weeks before deciding it didn't work. I'm sorry, it was long ago and my memory is not great.

 

Best wishes to you.

Link to post
Share on other sites

@Leila I might be asking this in the wrong place....but how are you doing? I saw you reply on another post....just thought I would check in with you. :)

 

2005-2017 started on AD for sleep then on and off Paxil, Zoloft, Lexapro, and others that I can't remember

2017 Lexapro 10 mg

2018 Jan-Tried getting off lexapro. (within about a 4-6 week period) 

2018 March- Got back on Lexapro 10mg

2018 June Switched to Wellbutrin. (don't remember dosage)

2018 August Switched to Sertraline. 25 mg, 50, 75, then back down to 50 

2019 December...back on Sertraline 25 mg 

2020 January-switched back to Escitalopram 5 mg

2020 March-December Escitalopram 10 mg

2021 Jan-started BMS taper w/2 wk hold (using liquid form)

2021 July 6.03 mg

Occasionally .25mg Melatonin (as needed)

Link to post
Share on other sites
  • Mentor
On 1/25/2021 at 10:11 PM, Krisseyb said:

@Leila I might be asking this in the wrong place....but how are you doing? I saw you reply on another post....just thought I would check in with you. :)

 

Thank you for asking, @krisseyb! I will update my thread soon! :)

July 2015: the 20mg citalopram for great stress begins

After two years I start tapering (slow but without medical advice) and I guess wrongly. First up to 10 mg, then 5 mg and 2 mg (liquid solution) and skips

January 2020 (I don't remember exactly the day): off citalopram (last dose 2mg).

June 2020: adrenal crash. The beginning of Hell on Earth

 

Current supplement:

- saffron pill (20 mg) + vit. E, omega 3 (EPA + DHA) 2g, magnesium bisglycinate 300 mg, iron , vitamin D3 (2500ui) +K7 (50 ui), vitamin C (1g) + quercitin (25 mg), theanine (as necessary).

 

Try meditating / mindfulness, walking every day, CBT/ACT, massage.

 

"E quindi uscimmo a riveder le stelle" ("And so we went out to see the stars again")

(Dante Alighieri, Divine Comedy , Inferno, XXXIV, 139)

Link to post
Share on other sites
  • 4 months later...

Did you try it @Leila

 

I want to try it for my sensitive skin.

2019 oct - fluoxetine 10 mg 7 weeks (didn't work).     2020 feb - paroxetine 10mg for 5 months, tapered down in 1 month 9.8mg 9.6mg 9.4mg and so on.        2020 oct - paroxetine 10mg after 2 months I restarted the use of it because of WD symptoms 10mg (too much) then the (physical) problems started, after 2,5 months I tapered down in 2 weeks.

since 31 december 2020 - drug free

Supplements: magnesium Biglycinate 250mg 2 times daily

 

Worst symptoms: always hypersensitive tingling skin/painful cold shivers/itchy jittery nerves/clothes, wind, cold air feels painful on skin/difficulty walking because of stiff legs - max 10-15min walk then cramped calves, so can't work atm./suicidal thoughts, these comes and goes.

 

Improved: aches/twitches (3/10)

 

"The place of true healing is a fierce place. It's a giant place. It's a place of monstrous beauty and endless dark and glimmering light. And you have to work really, really, really hard to get there, but you can do it."    Cheryl Strayed

Link to post
Share on other sites
  • Mentor

Dear @GVR91, I try it for about 5 months and still take it. I take 3 pills a day (1000 mg), not a very high dosage but my purpose is trying to findan help for muscle pain and a relief for dysmenorrhea. I don't know if my situation became better for a mix of strategies and supplements but, as for me, PEA as natural biological modulator is a valid help for neuropathy in some form like fybromialgia... The only thing is that it does not have an immediate effect (it takes time to see the effects) and you have to find the right dosage.

 

July 2015: the 20mg citalopram for great stress begins

After two years I start tapering (slow but without medical advice) and I guess wrongly. First up to 10 mg, then 5 mg and 2 mg (liquid solution) and skips

January 2020 (I don't remember exactly the day): off citalopram (last dose 2mg).

June 2020: adrenal crash. The beginning of Hell on Earth

 

Current supplement:

- saffron pill (20 mg) + vit. E, omega 3 (EPA + DHA) 2g, magnesium bisglycinate 300 mg, iron , vitamin D3 (2500ui) +K7 (50 ui), vitamin C (1g) + quercitin (25 mg), theanine (as necessary).

 

Try meditating / mindfulness, walking every day, CBT/ACT, massage.

 

"E quindi uscimmo a riveder le stelle" ("And so we went out to see the stars again")

(Dante Alighieri, Divine Comedy , Inferno, XXXIV, 139)

Link to post
Share on other sites
2 hours ago, Leila said:

Dear @GVR91, I try it for about 5 months and still take it. I take 3 pills a day (1000 mg), not a very high dosage but my purpose is trying to findan help for muscle pain and a relief for dysmenorrhea. I don't know if my situation became better for a mix of strategies and supplements but, as for me, PEA as natural biological modulator is a valid help for neuropathy in some form like fybromialgia... The only thing is that it does not have an immediate effect (it takes time to see the effects) and you have to find the right dosage.

 

Thanks a lot @Leila I want to try it also. but i'm a little hesitant to make things worse with a sensitized CNS. So i think about it ;) thank! But you had positive effects that's a good sign. Did you mention clearly positive effects from the PEA or is this difficult to say?

I have paresthasia full body from an adverse reaction. I don't know if this is neuropathy also or a messed up CNS.

2019 oct - fluoxetine 10 mg 7 weeks (didn't work).     2020 feb - paroxetine 10mg for 5 months, tapered down in 1 month 9.8mg 9.6mg 9.4mg and so on.        2020 oct - paroxetine 10mg after 2 months I restarted the use of it because of WD symptoms 10mg (too much) then the (physical) problems started, after 2,5 months I tapered down in 2 weeks.

since 31 december 2020 - drug free

Supplements: magnesium Biglycinate 250mg 2 times daily

 

Worst symptoms: always hypersensitive tingling skin/painful cold shivers/itchy jittery nerves/clothes, wind, cold air feels painful on skin/difficulty walking because of stiff legs - max 10-15min walk then cramped calves, so can't work atm./suicidal thoughts, these comes and goes.

 

Improved: aches/twitches (3/10)

 

"The place of true healing is a fierce place. It's a giant place. It's a place of monstrous beauty and endless dark and glimmering light. And you have to work really, really, really hard to get there, but you can do it."    Cheryl Strayed

Link to post
Share on other sites
  • 4 weeks later...
  • Mentor

Ehi @GVR91! Sorry for my late answer but I didn't receive the message with my tag! Do you try PEA supplement? I read many studies that prove the validity at the level of peripheral neuropathy especially with regard to mast cell modulation which I assume for me is involved in bowel and menstrual pain. 

July 2015: the 20mg citalopram for great stress begins

After two years I start tapering (slow but without medical advice) and I guess wrongly. First up to 10 mg, then 5 mg and 2 mg (liquid solution) and skips

January 2020 (I don't remember exactly the day): off citalopram (last dose 2mg).

June 2020: adrenal crash. The beginning of Hell on Earth

 

Current supplement:

- saffron pill (20 mg) + vit. E, omega 3 (EPA + DHA) 2g, magnesium bisglycinate 300 mg, iron , vitamin D3 (2500ui) +K7 (50 ui), vitamin C (1g) + quercitin (25 mg), theanine (as necessary).

 

Try meditating / mindfulness, walking every day, CBT/ACT, massage.

 

"E quindi uscimmo a riveder le stelle" ("And so we went out to see the stars again")

(Dante Alighieri, Divine Comedy , Inferno, XXXIV, 139)

Link to post
Share on other sites
×
×
  • Create New...

Important Information

Terms of Use Privacy Policy