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Oriyah: Remeron withdrawal insomnia hell


Oriyah4

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Hello -- I'm so glad to have found this site. I really need help. 

 

I was prescribed 7.5 mg Remeron about a year ago (I think February 2020) due to health anxiety. Before being prescribed this drug, I had never had any sleep issues whatsoever. The Remeron was great for my anxiety for awhile (I think I was on it about 7 months), but then I began to notice that, when taking handwritten notes in interviews with clients (I'm an attorney), I was frequently skipping over letters (e.g. would write "cient" instead of "client" and then immediately notice and go back and add in the letter) -- this was something I'd never noticed happening before. I also didn't like the feeling I had when waking up in the morning -- for the first few minutes, I felt like I was still asleep, but I also 100% knew that I was awake. It was very disconcerting -- felt like I was losing my mind -- and I knew I wanted to get off the medication.

 

My psychiatrist said, "no problem, you're at a super low dose, just quit." I did that and immediately could not sleep a wink and had no appetite at all. I suffered through that for a few weeks, but it was simply intolerable by that time and not getting better. I found a Remeron FB group that suggested reinstating.

 

So, I reinstated at about 2.5 mg in, I guess, September 2020? and that helped reduce the initial intolerable withdrawal symptoms a lot. But then I started having awful GI symptoms. I went to a gastroenterologist after weeks of that and was told I needed a colonoscopy. The results of the colonoscopy were normal, and my symptoms finally subsided. As that was going on, I was slowly reducing my dose via a liquid preparation my pharmacy prepares for me. I stayed at 2.5 for September, then 2 for October, then 1.05 for November, then down by .15 mg per week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021.

 

I also started on buspirone (5 mg 3 times a day) to help deal with my anxiety in November, a drug which seems to be more benign than many other alternatives.

 

I stayed at .15 on the Remeron (an amount so small that I could barely taste it!) until 3 days ago, when it felt absolutely ridiculous to continue, so I stopped. To be honest, my sleep kept getting worse and worse throughout November and December -- I would wake up several times a night -- but each time I'd be able to fall back asleep pretty easily, so it was tolerable. Then, the day I completely stopped taking the .15 mg, I couldn't sleep more than an hour. I was tired and fell asleep at the regular time, then woke up with a racing heart an hour later. The rest of the night I got no sleep at all. The next day, I decided to take the .15 mg again, which maybe helped a little, but I also took 2 benadryl, so it might have been that that was helping -- at any rate, I slept for 3 hours that night.

 

Yesterday, I took the .15 mg again and also took .5 mg of melatonin. I got 3.5 hours of sleep, woke up at 2 am, took another .25 mg of melatonin, and slept fitfully the rest of the night (waking up on the hour but eventually falling back asleep again, such that I may have gotten another segmented 2.5 hours of sleep).

 

With my health anxiety, I'm really worried that I've permanently ruined my ability to sleep normally, or, in particularly dark moments, I start worrying that some other cognitive degeneration is happening (I'm only 39!), because it doesn't seem possible that such a small amount of Remeron could be having such extreme effects. My psychiatrist (a different one now than the one who originally prescribed Remeron) said he's been practicing for 45 years and never seen anyone have trouble coming off of Remeron. He's trying to prescribe me a benzo to help me sleep and I really don't want to go there.

 

Any advice??? I don't know if I should go back to a higher dose of Remeron again, and if so, what dose, or if I should stay off and rely on Melatonin to get whatever sleep I can until sleep gets back to normal (if ever???) I would be so appreciative of any advice.

Edited by manymoretodays
name to title, spacing of block text done
  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
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  • manymoretodays changed the title to Oriyah: Remeron withdrawal insomnia hell

Titled:  Moderators, please, I need help

 

Still waiting for my introduction post to be approved. I cannot sleep more than 2 hours a night, and it’s been this way for 2 weeks. Melatonin isn’t even really working anymore. Please, please send advice. I can’t tolerate this and know I need to reinstate. But reinstating at .3 mg did nothing at all. Please, someone, please send advice to let me know what mg to reinstate at. I’m desperate. Thank you.

Edited by manymoretodays
title added, merged to topic
  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
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  • Moderator Emeritus

Hi Oriyah4 and welcome.

Apologies on the delay getting you started.  And thank you, thank you for getting your signature nicely done!

 

So just the last 2 weeks with the overwhelming insomnia?

Has this gotten worse since you started the Buspirone?

Buspirone Side Effects: Common, severe, long term- Drugs.com

and Drugs.com, is an excellent site to not only check out any medications/drugs before taking them, but also to do interactions checks on as well

And then, was the anxiety your biggest symptom, since coming off the Remeron/mirtazapine?

 

Buspirone is also a drug that we would recommend a taper on.

Tips for tapering off buspirone(Buspar)

 

And okay, more on WD(withdrawal) symptoms:

 

Dr Joseph Glenmullen's withdrawal symptom checklist

 

We advocate for a more harm reduction approach to tapering:

Why taper by 10% of my dosage?

And then sometimes, at the lower doses, when tapering, one needs to go even slower or lessen the percentage drops.

 

Do you remember at which dose of Remeron you were doing okay with?  And then, this may have been prior to your addition of Buspar.

 

*Tips for tapering off mirtazapine(Remeron)

And then, are you still taking the Remeron now?  I'm a bit confused as to your dosage, as well.  What concentration do you have of Remeron?  And are you taking 1 mg or 0.15 mg. 

What does the label on the bottle say?

Usually there are so many mg's(milligrams) per mL's(millileters).

The millileters are the volume, sometimes abbreviated to ml, mL, or cc

 

 

Would you do an interactions check, on Buspar and Remeron there, and then either link us to it, or copy and post right here, in a reply box.  Drugs.com interactions checker

 

And then when do you take your drugs, the time(s) daily?

 

So I am guessing that you are experiencing a lot of WD(withdrawal) now. 

What is withdrawal syndrome?

Brain remodeling

 

And then we often find a non-linear recovery from WD too.

The Windows are Waves Pattern of Stabilization

 

When we take medications, the CNS (central nervous system) responds by making changes over the months and years we take the drug(s). When the medication is discontinued, the CNS has to undo all the changes it made.  The CNS likes stability. Rebuilding the neurotransmitter production and reactivating the receptor and transporter cells takes time -- during that rebuilding process symptoms occur. And sleep is really important during withdrawal.  Insomnia is no small deal. 

 

And I'm sure you know that, about the insomnia.......it can make things all feel really tough.

 

You may have a bit of a drug interaction going on too, although with your lower dose of Remeron now, hopefully less likely.........but possible.

Best to space interacting drugs apart by at least 2 hours too.  That's something you can more immediately do, while we get to know you, and your case a bit better.

 

And okay, finally.......what you want to know more about.
About reinstating and stabilizing to reduce withdrawal symptoms

and this does apply to updosing too

 

I'm going to stop here, and get you approved now, give you chance to digest more information too.  We can also get into some more non-drug coping too, if you have not found much on your own yet.

 

This is your introduction/journal page where you have now introduced yourself to the community, you can ask questions here regarding your tapering, give updates, and just keep a record of your journey.

 

Welcome again.  And apologies........ as w e would really like to get to everyone started, within 24 hours, but sometimes it is just not possible.  Forgive.

 

Love, peace, healing, and growth,

manymoretodays(mmt)

Edited by manymoretodays
futher formatiing, tapering mirtazapine link added

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

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Thank you so much for your response, MMT. Sorry to be so desperate. I'm very much at my wit's end and am incredibly grateful to hear from you. Recovering from these drugs is such a lonely road to go down. It's so easy to feel like you're losing your mind.

 

I've had issues with waking in the night for awhile now. I don't remember how long. Probably ever since I reinstated at 2.5 mg. I would usually just fall right back to sleep when I woke up, though. It's just been in the last 2-3 weeks (when I was as .3, then .15, then zero mg) that I started waking up in the middle of the night unable to go back to sleep at all.

 

I don't believe that the insomnia has gotten worse since starting the Buspirone. The Buspirone has helped control (though not completely) waves of anxiety. My hope is that I can get completely off of Remeron and then tackle getting off Buspirone. I've seen a couple of references online, here and elsewhere, of folks having trouble with Buspirone taper, but it doesn't seem to be anywhere near to the extent that they have trouble with Remeron.

 

The only interaction between the two drugs on drugs.com is regarding the risk for serotonin syndrome. I have been trying to be careful not to take the two within a couple hours of each other. I usually take Buspirone at 7 am, 3 pm, and 10 or 11 pm, and had been taking the Remeron at about 8 pm. I haven't taken any Remeron for about a week now (except one night when I tried taking .3 mg of Remeron but it didn't help).

 

I was basically still "OK" (could tolerate symptoms) until I got down to about .3 mg (my liquid is 7.5 mg medicine/5 mg liquid, so I'm figuring that there is .15 mg medicine in .1 mg liquid). At .3 mg, my spouse and my psychiatrist were telling me just to get off of it, it couldn't possibly be causing the symptoms I thought it was. I'm wondering if tonight I shouldn't try reinstating at .6 mg (.4 mg of liquid) or maybe .9 mg (.6 mg of liquid).

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment
  • Moderator Emeritus

Hi Oriyah,

I can get back to you later today.  Happy Monday. B)

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

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Thanks, MMT! Quick update: I took .4 mg (=.6 mg of actual remeron) last night to see how it would go. Sweet relief: I could sleep again. I woke up at least 5 or 6 times, but fell back asleep fairly quickly. So now my question is: should I take a little more so that I start my taper from a place where I sleep soundly through the night and don’t wake up? Or should I just hold here at .6 mg for awhile? And at what point will I know I’m ready for a decrease?

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment
  • Moderator Emeritus
On 1/17/2021 at 1:43 PM, Oriyah4 said:

The only interaction between the two drugs on drugs.com is regarding the risk for serotonin syndrome. I have been trying to be careful not to take the two within a couple hours of each other. I usually take Buspirone at 7 am, 3 pm, and 10 or 11 pm, and had been taking the Remeron at about 8 pm. I haven't taken any Remeron for about a week now (except one night when I tried taking .3 mg of Remeron but it didn't help).

 

I was basically still "OK" (could tolerate symptoms) until I got down to about .3 mg (my liquid is 7.5 mg medicine/5 mg liquid, so I'm figuring that there is .15 mg medicine in .1 mg liquid). At .3 mg, my spouse and my psychiatrist were telling me just to get off of it, it couldn't possibly be causing the symptoms I thought it was. I'm wondering if tonight I shouldn't try reinstating at .6 mg (.4 mg of liquid) or maybe .9 mg (.6 mg of liquid).

 

Hi Oriyah4,

Well, later today......B) Barely, if I don't sign off soon, it will be tomorrow.

And okay, yah, but on the serotonin syndrome, it comes in all different degrees, you know like milder, moderate, or heavy duty.  But......your mirtazapine dose is so low too. 

But if things went awry after your Buspar addition, then......well.......likely that it may not have helped at all.  I guess that was all I wanted you to take stock of.

 

And I did the math too, on your concentration of 7.5 mg per 5 mL, and came up with the same numbers, or .15 mg per .1 ml

 

And okay then, you had been off the Remeron for about a week.

6 hours ago, Oriyah4 said:

hanks, MMT! Quick update: I took .4 mg (=.6 mg of actual remeron) last night to see how it would go. Sweet relief: I could sleep again. I woke up at least 5 or 6 times, but fell back asleep fairly quickly. So now my question is: should I take a little more so that I start my taper from a place where I sleep soundly through the night and don’t wake up? Or should I just hold here at .6 mg for awhile? And at what point will I know I’m ready for a decrease?

 

I'd say to stick with the .6 mg now.  Go with the same dose for a week.  It's usually 4-7 days for most drugs to see more clearly if a reinstatement, or updose sometimes, is going to be effective.  So I'd suggest you stick with the .6 mg.  You might not get perfect sleep, but I'm sure at this point any improvement will be grand.

 

Also:  Tips to help sleep: so many of us have that awful withdrawal insomnia

I'd suggest you scour this topic, for any non-drug coping....... that could really help too

 

And oh yes, a good HOLD, and a chance for your nervous system to stabilize a bit, and then after several months, you can begin a taper.  And even then, you can do a gradual taper, 10% or less, from each previous dose.  You could further dilute your liquid to do so.  And you don't even have to discuss it with your doctor or others, until perhaps comfortable doing so.  Maybe after the fact.

 

Please do update.  And ask if anything else comes up as far as questions.  We have so much information here, and I'm happy to point you towards it, and even help you learn how to search for it too.

 

Best, L, P, H, and G,

mmt

Edited by manymoretodays

Late 2023- gone to emeritus status, inactive, don't @ me, I can check who I've posted on, and I'm not really here like I used to be......thanks.

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016.  And.....I quit smoking 11/2021. Lapsed.  Redo of quit smoking 9/28/2022.  Can you say Hallelujah?(took me long enough)💜

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider.  My success story:  Blue skies ahead, clear sailing

 

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Mmt, tonight I took the .6 mg and my sleep was as bad as it was before I reinstated. It seems like yesterday was a fluke (or maybe I was just so exhausted that i managed to overcome insomnia for one night). I’m planning to try .9 mg tomorrow. Is there any problem with trying that?

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment

Ok, I decided to stick with .6 mg for awhile for stability’s sake and have been on .6 mg for 5 nights now (after my too-fast taper to zero). And am also using melatonin. I take 1 one mg melatonin, fall asleep for 2 hours, wake up and take another 1 mg melatonin, fall asleep for 2 hours, take another melatonin, and from that point (usually around 2 am) I am tossing and turning the rest of the night, maybe getting a bit of sleep here and there but mostly awake. Now that it’s been 5 days without great improvement, should I increase my dose some, or just hold tight at .6 mg a little longer??? I wonder if I shouldn’t have just stuck it out at zero, since it seems like I’m going to suffer regardless. And at least at zero I didn’t have another year of tapering ahead of me. Maybe I could still do that if I do it now, before my body gets too used to the .6 mg again. Please help...

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment

Hi Oriyah:

 

Yes, it is tricky to get re-stabilized when doing an updose.  I had to do it 2017 from 1.87 mg. to 3.75 mg. and it took about 35 days for me to stabilize with some 0 sleep nites thrown in.  So hang in there -- I think better nites are ahead.  

 

Also, Omega 3s might be a little stimulating to the CNS so you might want to consider "on hold" for right now.  Are you taking Vit D in the a.m.s?

 

Best regards,

Shebon

Started 3.75 mg. remeron 4/2013.  Had tapered off benzo 4/2011.  Had tapered down to 1.87 mg remeron but mistakenly thought I was in bad withdrawals, when it was Synthroid again.  Stopped  Synthroid 3/31/3021-side effects are the same as hyperthyroid symptoms, but doctors have no knowledge of this side effect.  Started taper end of 7/2021, now at 3.48 mg. daily. 

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Oriyah4,

I SO share your pain! I so wish I could just figure it out for you (and for me!), as the stress of "too much? not enough? up? down?" is really hard. The worst part is that, at least according to me, you have to wait to see the effects apparently. Our instincts are immediate: If I do X and feel bad, X made us feel bad. But maybe doing X actually helps us four days later, or a week later? So really trying to keep track of symptoms over time and noting other things (like diet, exercise, supplements etc.) is important so you CAN ultimately make smart decisions. There are different suggestions here for journaling or symptom tracking. Me, I scrapped my more complex forms and just have a notebook like this:

 

Night before: Slept 9:30-2:30, read, some dozing from 4-6. (5h +2dozing)

8am - out of bed, took dose of 0.xx, +magnesium with breakfast

10am - still unmotivated, depressed, tired.

12pm - some improvement - going for walk

1pm - big lunch, mood improved, mild headache. 

 

etc. 

 

That way I can see, for example, that I almost always improve as the day goes on, and I can look back and see if, for example, taking the dose in the morning or evening makes a difference. 

 

But I totally share your pain! I'm still in the same problem: after a great deal of agonizing, I've decided my reinstatement is a failure, so I'm going down/off. A couple of days after going down, certain symptoms seemed to have gone away (HURRAH!). So of course I rejoice and think I've made the right decision. But then, all day yesterday and last night were again pretty awful. So maybe I didn't?? ARG! But it looks like you've found a knowledgable moderator, which can be reassuring. The idea of making longer decisions to allow some stability seems to be very common advice - decide after a week, not every day. 

 

Finally: Insomnia is such a common symptom here, but you really haven't had it for too long yet (not at all to belittle your suffering!). My point is that it might actually turn out to be fairly short lived now you've tried to nip it in the bud so quickly. I have high hopes your symptoms will resolve! Hang in there!

15+ years Citalopram 10mg (sometimes 20?)

2019 Citalopram 5mg. No problem reduction.

2020 Citalopram 5mg to zero. (Feb)

2020 (Feb - mid Oct): Very rare use of 0.125 or .25mg Xanax for really bad symptoms

2020 (Feb - Nov): Occasional use of "Nytol" sleep aid (an antihistamine). 

2020 Failed reinstatement: Escitalopram by accident (not Citalopram).  

 -- using a scale, started July 27 0.5mg, doubled every week or so to reach 5mg by Aug 30. Too fast - terrible depression, quit.

2020 (Oct-current): Supplements:

 -- Morning: Magnesium 300mg, Omega 3(483 EPA, 360 DHA +Vit E) Night: Liquid Valerian/Passiflore/Escholtzia - French organic herbal sleep aid, 1.9mg LD Melatonin 

2020 Current - new Citalopram reinstatement. (Accidentally started with Escitalopram before realizing and switching to Citalopram Oct. 30)

 -- using pipette method: Oct 30, 0.25mg; Nov. 4th, 0.375; Dec. 1st 0.5mg, Dec. 21st 0.75mg Jan 19: Decide reinstatement fail: Jan 21 0.625mg, Jan 28: 0.5mg Feb 8 0mg

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  • 7 months later...

Aaaand…I’m back. I was hoping this would be a success post! I finally finished my super-slow taper 2 weeks ago. I jumped off at .075 mg because it was impossible to go lower than that (that was .05 mg of liquid, not even enough to taste). The whole time during this final taper after reinstatement I waited until withdrawal symptoms were tolerable before decreasing 10% and then holding at least 4 weeks until the next drop. But now that I’m 100% off, my insomnia is as bad as it was back when I first cold-turkeyed off of 7.5 mg a year ago! In other words, I can only sleep about an hour at a time, if at all, then wake up wide awake and full of fear because of something I dreamed that didn’t even happen in real life. It is awful. I feel like I did all the right things, and yet I’m back at square 1 now that I’ve stopped taking a dose so tiny that it makes no sense it should affect me like this. And of course all the solutions for insomnia a doctor can offer are more drugs. I hope this is just a really bad wave, but I have to do something to get some sleep if it doesn’t end soon, and melatonin, ear plugs, magnesium, eye mask, and weighted blanket aren’t really helping. Why is this happening after I did everything I was supposed to do???

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
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On 9/13/2021 at 6:43 AM, Oriyah4 said:

Aaaand…I’m back. I was hoping this would be a success post! I finally finished my super-slow taper 2 weeks ago. I jumped off at .075 mg because it was impossible to go lower than that (that was .05 mg of liquid, not even enough to taste). The whole time during this final taper after reinstatement I waited until withdrawal symptoms were tolerable before decreasing 10% and then holding at least 4 weeks until the next drop. But now that I’m 100% off, my insomnia is as bad as it was back when I first cold-turkeyed off of 7.5 mg a year ago! In other words, I can only sleep about an hour at a time, if at all, then wake up wide awake and full of fear because of something I dreamed that didn’t even happen in real life. It is awful. I feel like I did all the right things, and yet I’m back at square 1 now that I’ve stopped taking a dose so tiny that it makes no sense it should affect me like this. And of course all the solutions for insomnia a doctor can offer are more drugs. I hope this is just a really bad wave, but I have to do something to get some sleep if it doesn’t end soon, and melatonin, ear plugs, magnesium, eye mask, and weighted blanket aren’t really helping. Why is this happening after I did everything I was supposed to do???

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment

Oriyah,

 

I'm sorry to hear that you are suffering ... I know (as many others here) how it feels to "live" with insomnia.

 

Just my 2cts:
* Your taper was not "super slow" IMHO ... others learned the hard way that this process may last for many, many years. So I do not know whether this is protracted withdrawal from beginning of the year (you made some significant reductions in a short period) or you jumped too early to zero.

 

* A lower dose is possible. Just dilute the liquid or look for "endgame support" here. And even 0.075 mg mirtazpine is still quite a lot of molecules which may affect your brain. 
I managed to get rid of remeron quite recently, went from 0.5 in January to 0.025 mg/day in July and jumped. I feel an impact on sleep, but so far it is OK for me (some 5-6 hours per night).

 

* I see you tried a lot of sleeping aids. For me something like a white noise generator (in my case just an app on my smartphone playing a sea wave sound) helped to get back to sleep. Maybe worth a try.

 

Good luck! 

 

Hamster

Nov 2018: St. John's Wort 900 mg Extract / day Dec 2018: fast taper of St. John's Wort  (900 mg -> 0 in about 2 weeks)
Jan 2019: start of  citalopram (10 mg/d) and mirtazapine (30 mg/d) Feb 2019: citalopram increased to 20 mg/d, start of talk therapy
March 2019: 10 mg/d citalopram & 15 mg/d mirtazapine April 2019: 7 mg/d citalopram & 7.5 mg/d mirtazapine
May 2019: 5 mg/d citalopram & 5 mg/d mirtazapine June 2019: 5 mg/d citalopram & 3.75 mg/d mirtazapine

July 2019: 5 mg/d citalopram & 3.12 mg/d mirtazapine July 16th 2019: 5 mg/d citalopram & 2.5 mg/d mirtazapine

August 22nd 2019: 5 mg/d citalopram & 2.2 mg/d mirtazapine September 20th 2019: 5 mg/d citalopram & 2.0 mg/d mirtazapine -> BM slide (around 2%/week, some holds). Feb 2020: 3.4 mg/d citalopram & 1.5 mg/d mirtazapine, Jan 2021: 0.9 mg/d citalopram & 0.5 mg/d mirtazapine, July 2021: 0.0 mg - drug free!

Supplements: linseed oil for omega3 (can't tolerate fishoil), magnesium, B12 and folate

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Thank you so much for the response, @Hamster. It means a lot.

 

In my search for "endgame support" under the "tapering" tab, I see a post by @brassmonkey stating that the topic is under construction. Is there anywhere else on the site where you could point me?

 

I went from .6 mg in January to .075 in September, which was .05 mg of liquid. During my taper, I felt like I was keeping symptoms under control (same as you, 5-6 hours a night of sleep). I was being a little dramatic in my original post -- my insomnia isn't as bad now as it was when I originally went cold-turkey off of 7.5 mg. But it's pretty bad. Last night was another 2-hours-of-sleep night.

 

Should I seriously reinstate at, like, .025 mg of liquid (.04 mg of medication)? Or should I just stick it out at this point? By sticking it out, does it just mean that symptoms will be a little bit worse for a little bit longer than if I kept tapering tinier amounts? Or am I damaging my brain in a way that I wouldn't be if I kept tapering a half a droplet? I don't think my psychiatrist will agree to prescribe any more to me.

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment
  • Moderator

Reinstatement will be dependent on if you can get a new prescription. Reinstating, stabilizing and tapering off is going to take many months and any liquid you may have now will not last long enough. There might be enough volume wise, but once opened a bottle is only good for a short period of time. If you can get more then reinstating at .025 would be a workable place to start. If you can't get the new prescription then riding it out is the other option. It could be quite uncomfortable at times, but it will not do any permanent damage.

 

We need to clarify the units of measure that you are using. The volume of a liquid dose is measured in mL where as the strength of the dose is measured in mg.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Final Dose 0.016mg.     Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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Thank you, @brassmonkey. It's reassuring to know that I'm not doing any permanent damage by riding things out at this point. And thank you for the clarification around units of measure!

 

A friend suggested I try Delta-8 gummies to help with sleep. I found a Delta-8 brand that publishes 3rd party independent lab results to confirm purity of its product, which I've read is important since the industry is totally unregulated. I didn't have high hopes (ha! high hopes!) because I have tried EVERYTHING since Remeron withdrawal symptoms started and always wake up every 2 hours, often unable to doze off again. For the last three nights, though, I've had half a gummy at bedtime (about 12 mg of Delta-8) and slept for 6-7 hours straight! I don't know how safe it is to keep relying on Delta-8 on an ongoing basis, but for now, it's a huge relief.

 

Does anyone else have experience with Delta-8 for insomnia relief, or any insight or cautions to share?

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment
  • Moderator

It depends on which Delta-8 product you are using. I appears to come in both CBD and THC verities. The THC is a definite no, it directly affects several neurotransmitters, so plays badly with the medications we are trying to get off of. CBD also interacts with them but to a much lesser degree. Occasional use to help with sleep may be safe, but I wouldn't do it too often.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Final Dose 0.016mg.     Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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  • 2 weeks later...

Writing with a hopeful update, since I know how much I've depended on those during the worst of withdrawal. It's been almost 2 weeks now of better sleep than I've had in a year and a half. I still take 300 mg of magnesium and 3 mg extended release melatonin a night, and I still wake up 2 or 3 times every night. But I've been falling right back to sleep and then sleeping until 6 or 7 am for a total of about 7 hours of sleep a night. I've had these reprieves for a period of maybe 2-3 days at a time before, but this is the first time it's been for this long since starting my taper. And I've been feeling so so so much better. I'm still having anxiety spikes but they're easier to manage when decently well-rested. I'm also functioning cognitively a lot better with better sleep (go figure)!

 

Working to taper off of the Buspirone now. I'm just taking 5 mg twice a day at this point. Losing the first 5 mg of the 15 mg I've been on for close to a year didn't cause any big issues. It has never had the same kind of super-potent effects that the mirtazapine did so I'm feeling confident that I'll get off of it much more easily, but, of course, I'll still tread carefully.

 

Of course I'm trying to keep in mind that I shouldn't be surprised when the next wave hits. But in starting to experience longer windows, hope is starting to return that I might one day feel "normal" again! Stay strong, everyone!

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment

Thank you Oriyah4 for posting. I am tapering from 7.5mg of Mirtazapine and am also on Buspirone. It’s so nice to read about someone successfully kicking this poison!

2005-2013 Ambien 5mg. Stopped taking with little problem

12/20 Buspirone 7.5mg 2x daily

5/22 CT from Buspirone- no WD

12/20 Mirtazapine 7.5mg 1x daily

2/11/21 17% reduction homemade Mirtazapine liquid to 6.2ml, 3/27/21 5.9ml, 4/23/21 5.6ml, 5/8/21 5.3ml, 5/28/21 5.0ml, 6/13/21 4.88ml, 6/20/21 4.75ml, 7/2/21 4.62ml, 7/12/21 4.5ml 7/25/21 4.37ml, 8/4/21 4.24, 8/17/21 4.10, 8/27/21 3.96, 9/23/21 3.84, 10/8/21 3.72, 11/13/21 3.5, 12/13/21 3.3, 1/9/22 3.1mg, 2/10/22 2.9mg, 3/9 2.7mg, 4/8 2.5mg, 5/22 2.3mg, 5/28 CT Buspirone, 7/24 2.2mg, 8/24 2.05mg, 9/14 1.9mg

10/11 1.75 11/12 1.6, 12/3 1.47, 1/3/23, 1.35, 2/1 1.24, 2/23 1.14, 3/17 1.03, 4/7 .93, 4/27 .83, 5/18 .75, 6/13 .67, 7/17 .59, 8/7 .52, 8/25 .50, 9/1 .48, 9/23 .43, 10/22 .38, 11/5 .33, 11/20 .28, 12/4 .24 12/18 .20, 12/31 .15, 1/14/24 .10, 1/30 .07, 2/18 .04, 2/25 0, drug free

 

Supplements: 4,000iu vitamin D, Vitamin K, Probiotic, 400mg magnesium glycinate, 250mg vitamin C, Fish Oil, collagen peptides, CBD or CBN as needed for sleep,  Ginger Tummy Drops as needed

 

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@Gigi68, I *hope* I've kicked it. Withdrawal has been so protracted and unpredictable that I'm not ready to call myself a success story yet. But I had another good night of sleep last night and so grateful for it. The best advice I can offer you is to listen to your body rather than strictly following the tapering schedule you've written on your calendar. Things went much better for me when I was willing to hold at a certain amount until I felt better. Of course, I never felt great at any point while I was still taking the mirtazapine, but I started to learn what a "decent streak" felt like and made myself wait there for a couple of weeks before making another reduction. 

 

Please don't be surprised if it gets harder to taper as you get closer to zero. That was definitely the case for me. It's so frustrating to have to go slower as you get closer and closer to the finish line, but for me, it's been absolutely necessary.

 

Feel free to message me anytime.

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment

Thank you! I appreciate that and I’m sure I will be taking you up on your offer. I feel like I’ll be doing this for the rest of my life (I’m 69). 😞

2005-2013 Ambien 5mg. Stopped taking with little problem

12/20 Buspirone 7.5mg 2x daily

5/22 CT from Buspirone- no WD

12/20 Mirtazapine 7.5mg 1x daily

2/11/21 17% reduction homemade Mirtazapine liquid to 6.2ml, 3/27/21 5.9ml, 4/23/21 5.6ml, 5/8/21 5.3ml, 5/28/21 5.0ml, 6/13/21 4.88ml, 6/20/21 4.75ml, 7/2/21 4.62ml, 7/12/21 4.5ml 7/25/21 4.37ml, 8/4/21 4.24, 8/17/21 4.10, 8/27/21 3.96, 9/23/21 3.84, 10/8/21 3.72, 11/13/21 3.5, 12/13/21 3.3, 1/9/22 3.1mg, 2/10/22 2.9mg, 3/9 2.7mg, 4/8 2.5mg, 5/22 2.3mg, 5/28 CT Buspirone, 7/24 2.2mg, 8/24 2.05mg, 9/14 1.9mg

10/11 1.75 11/12 1.6, 12/3 1.47, 1/3/23, 1.35, 2/1 1.24, 2/23 1.14, 3/17 1.03, 4/7 .93, 4/27 .83, 5/18 .75, 6/13 .67, 7/17 .59, 8/7 .52, 8/25 .50, 9/1 .48, 9/23 .43, 10/22 .38, 11/5 .33, 11/20 .28, 12/4 .24 12/18 .20, 12/31 .15, 1/14/24 .10, 1/30 .07, 2/18 .04, 2/25 0, drug free

 

Supplements: 4,000iu vitamin D, Vitamin K, Probiotic, 400mg magnesium glycinate, 250mg vitamin C, Fish Oil, collagen peptides, CBD or CBN as needed for sleep,  Ginger Tummy Drops as needed

 

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Hi Oriyah,

 

I'm also in withdrawal from Mirtazapine, probably a few months behind you in terms of timescales. I was wondering if you ever struggle/d with a 'wired' feeling?  Often when I've had very little sleep I seem to become paradoxically more cognitively alert than when I've had more?   Have you struggled with derealisation feelings at all?   The other thing I have noticed is a lack of getting sleepy after meal times which used to be a hallmark of my metabolic make-up

 

Thanking you in advance, and hope your wave is still waving ;)

2020 July-November 15mg mirtazapine (5 months)

2020 December 7.5mg (1 month)

2021 Jan-April 7.5mg to 0mg (4 months)

 

 

 

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  • 4 weeks later...

Hi wadh3301, sorry I'm so slow to respond! I did sometimes have a wired feeling even after not being able to sleep all night. Then I would pass out on the couch at 8 pm, wake up again at 9:30 wide awake, fall asleep again at 11, wake up at 1:30, so on and so forth. I don't think I ever felt more cognitively alert, though. All through withdrawal I had horrible brain fog. Brain fog that terrified me into thinking I was losing my mind or developing early onset dementia.

 

I don't exactly know what derealization is, so I don't know if I experienced that?

 

How are you doing now? I hope you're still taking it one step at a time and starting to see the light at the end of the tunnel!

 

I've had a few waves since I last posted, but for the last week, I had 7 hours of uninterrupted (or nearly uninterrupted) sleep a night and NO anxiety spikes!!!  I'm also having a huge breakthrough in therapy that is helping. And the worst of my brain fog has lifted during the last week as well. I think...I'm really recovering! Again, still hesitant to say so definitively, but I haven't experienced this much relief in ages!

 

And I'm almost off the buspirone too! Just taking .125 mg right now (1/4 a tablet once a day) -- will take this for one more week then toss the rest!

  • Started 7.5 mg Remeron in February 2020
  • Stopped CT in August 2020, I think?
  • Reinstated at about 2.5 mg in September 2020 (liquid taper)
  • Started Buspirone (5 mg 3x day) in November 2020 to deal with debilitating anxiety during remeron taper
  • Tapered to 2 mg for October, then dropped to 1.05 for November, and then down by .15 mg once/week for December (.9 first week, .75 second week, .6 third week, .45 fourth week, .3 fifth week) so that I was at .15 mg (1 mg of liquid) at the start of January 2021
  • Stopped in second week of January 2021 and couldn’t tolerate the insomnia, so reinstated to .6 mg and tapered slowly until Sept 2021 — jumped off at .075 mg because it was impossible to take less
  • Sept 2021, 0 mg remeron, 15 mg/day buspirone
  • Supplements: 300 mg magnesium, 3 mg melatonin, 2000 mg Vitamin D, Omega 3 (kelp-based)
Link to comment
  • 2 weeks later...

@Oriyah4 just interested to know if you kept up with the cbd?  I've had two attempts to get off mirtazapine, profound insomnia being the most pronounced symptom.

I'm encouraged to read your story 😊

2011 - started 15 mg mirtazepine. 2015- successfully tapered off. 2016 - Reinstated on 3.75mg as a sleep aid. July 2019 - 3.75mg Stopped working, increased to 15 then 22.5mg.Sept 2020 initiated slow liquid taper. Sept 2021 at 7.5mg for 3 months hit very bad withdrawals (also very stressed). Increased dose to 30 for 3 weeks then reduced to 22.5mg3rd Nov - Started magnesium supplement. 3rd Nov - started oestrogen hrt gel. 20th Dec - stopped oestrogen after 3 week taper. Currently still on 22.5mg mirtazepine and oral magnesium. 12/1 started with 1 capsule omega 3 fish oil. 14/ developed very loose motions so stopping the fish oil. 14/2/2022: after 5 months on the same dose decided to restart taper with a 5% cut: 21.4mg mirtazepine. Low histamine diet and magnesium. 14/03 reduced another 5% 20. 25mg 01/05 reduced to 19mg 01/06 reduced to 18.3mg 01/08 reduced to 17.3 mg 01/10 reduced to 16.5mg

 

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