Peter23 Posted January 16, 2021 Share Posted January 16, 2021 I can relate to so much that has been written here about antidepressants. I developed tardive dysphoria after being on them for 25 years. I am now virtually off antidepressants but still suffer terribly because of the tardive dysphoria. I feel suicidally depressed, anxious,worried and restless every day. I struggle to get out of bed and to get washed and dressed. Everything seems like an impossible task. I have been like this for over 2 years and despair that I will feel better. It took me about 18 months to taper off Sertraline. Does anyone else have experience with tardive dysphoria? Will I ever recover? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Administrator Altostrata Posted January 17, 2021 Administrator Share Posted January 17, 2021 Welcome, Peter. I moved your post here to start your Introductions topic, where you can report your progress and ask questions about your situation. How long have you been off sertraline? Did you have withdrawal symptoms while you were tapering? What does "tardive dysphoria" feel like to you? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Peter23 Posted May 3, 2021 Author Share Posted May 3, 2021 Thanks. I have been off Sertraline for about 3 months. I didn't have any withdrawal symptoms coming off it, as I tapered very slowly. The dysphoria feels like being in a constant state of low mood, severe anxiety, restlessness, worry and dissatisfaction. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Administrator Altostrata Posted May 4, 2021 Administrator Share Posted May 4, 2021 @Peter23 did you have any withdrawal symptoms as you came off? What method did you use to taper? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Peter23 Posted May 5, 2021 Author Share Posted May 5, 2021 No I didn't have any withdrawal symptoms as I came off Sertraline. I used the liquid form of the drug and reduced the dose by 10 per cent every four weeks. My problem is that I developed "tardive dysphoria " while I was on the drug. I have been on three antidepressants over the past 25 years. Venlafaxine (Effexor) 150mg : Sertraline 150mg : Mirtazapine 30mg. I was on both Sertraline & Mirtazapine for a few years so had to come off the Mirtazapine first and then the Sertraline. I am now off both of these drugs and feeling really awful. My psychiatrist tried me on Trazodone more recently and I felt even worse. So have now decided that I need to tough it out without any antidepressant with the desperate hope that my nervous system will eventually recover. I now accept that there is no pill to fix me. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Marmot Posted May 6, 2021 Share Posted May 6, 2021 Hi Peter, Welcome to the forum. Really sorry to hear what you have been put through. I also have the low mood and high anxiety since my taper. I don't have any answers for you, just letting you know that you're not alone. I guess my gardening helps me a bit with the struggle but that's about it right now, planted some wildflower seeds and hoping they sprout. Anyway, peace. 2004: Clonazepam and Celexa. 2005 - 2006: Effexor, then increased to high dose, then switched to Valproate and Seroquel. 2007: Wellbutrin + Strattera + Celexa. 2007 - 2008: Wellbutrin + Adderall + Paxil. 2008 - 2012: Wellbutrin + occasional SSRIs when I had worsened "depression", which happened around 4 times, usually after CT of WB. 2012 - 2014: WB + Sertraline, then WB + Pristiq (awful W/D) then WB + rTMS, then ketamine. 2014 - 2016: Wellbutrin 200 mg + Abilify 4 mg + Adderall 20-40 mg + Cipralex 20 mg. Oct 2016: "Tapered" Cipralex, felt outrageously anxious, irritable. Dec 2016: "Tapered" Adderall, then felt depressed, hopeless, fatigued. Feb 6 2017: reinstated 20 mg Adderall. Mar 2017: switched to Vyvanse, upped to 30 mg. May - Aug 2017: "Tapered" Vyvanse + Abilify to zero. Oct 25, 2017: Wellbutrin from 200 to 100 mg. Sep 10, 2018: Wellbutrin from 90 to 60 mg. Oct 29, 2018: WB from 60 to 50 mg. Dec 19, 2018: WB from 50 to 45 mg. Apr 15, 2019: WB 41 mg. May 14, 2019: WB 37 mg. Jun 8, 2019: WB 33 mg. Jul 22: WB 30 mg, then down by around 10% per month. Aug 2020: 0 Working hard to take my life back. Anything I say here is as a friend or peer supporter; it is not medical advice. Link to comment
Peter23 Posted May 6, 2021 Author Share Posted May 6, 2021 Thank you Marmot for your kind words of support. It means a great deal to know that I'm not alone. Sounds like you too are going through a really tough time. I do hope that things improve for you given time. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 6, 2021 Author Share Posted May 6, 2021 Do you think I should ask my psychiatrist for ECT? I feel so desperately unwell and afraid that I am going to commit suicide. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Fallensoul Posted June 2, 2021 Share Posted June 2, 2021 Peter, have you considered rtms? I also became in very bad shape after being on paroxetine for 18 years. I suffer almost 3 years now. I don't know what the cause is,( I hypothese downregulated serotonine receptors). I'm still in the tapering proces, after several faild attempts to other Ad's. I hope you will improve. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Peter23 Posted June 2, 2021 Author Share Posted June 2, 2021 Hi Fallensoul thanks for your message. Hope things improve for you. I'm not sure if rtms is available in the UK or on the NHS. I have now been off antidepressants for around 6 weeks. Having some better days, but also some very difficult days. Just hoping that antidepressant abstinence will allow my brain to heal gradually. With best wishes. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Fallensoul Posted June 3, 2021 Share Posted June 3, 2021 If you have better days, that's a good sign! Thanks and keep it up. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
JesusSavemefromWD Posted October 14, 2021 Share Posted October 14, 2021 On 6/2/2021 at 7:35 PM, Peter23 said: Hi Fallensoul thanks for your message. Hope things improve for you. I'm not sure if rtms is available in the UK or on the NHS. I have now been off antidepressants for around 6 weeks. Having some better days, but also some very difficult days. Just hoping that antidepressant abstinence will allow my brain to heal gradually. With best wishes. How are u doing? I feel dysphoria non stop after just 3.5 weeks on Zoloft, are u getting any relief? I hope so Aug. 16-17, 2020, cipralex: went CRAZY! Recovered in 24hrs Aug.28,2020; 3.5 weeks 25mg sertraline/4.5 weeks taper Oct. 25: Last dose (4mg) Symptoms while on zoloft DPDR/out of my body/soul despair/feeling dead; tinnitus/no appetite; fear, anxiety/panics 4 months OFF: soul despair, anxiety/fear, brain disconnection/ DPDR, brain feels swollen-numb/crazy/bedridden barely functioning, tinnitus, eye lid twitches; face spasms. Feeling slightly better after 10pm. - sleep & appetite are fine 9 months OFF: hell, no windows, same symptoms as above (only eye and face twitches have stopped) plus intense arm/shoulder pain and visual issues. Tinnitus replaced by head buzzing. 10 months-1 year: all above plus Insomnia (out of nowhere), depression, no peace of mind (mental Akathisia); 2.5mg melatonin 14months off: sleep resumed. All rest symptoms remain. Bedridden vegetable all day. DP is relentless. 1.5 years off: still severely disabled, not much changed except some improvement in vision. Link to comment
Peter23 Posted May 11 Author Share Posted May 11 I have been off Sertraline and Mirtazapine now for just over two years after a very slow taper. I didn't experience any significant withdrawal symptoms. However I think that I am suffering from tardive dysphoria which has not as yet resolved despite treatment with the non SSRI antidepressant Agomelatine. I have devised numerous strategies to survive day to day with this condition and am hopeful that given enough time my dysphoria will reverse just as frequently happens with those suffering from protracted SSRI withdrawal symptoms. It seems like that neuroplasticiy allows the brain to repair damage done by prolonged antidepressant treatment. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted May 15 Moderator Share Posted May 15 Hi @Peter23 welcome to SA. Can you pls fill in your drug signature so we are able to help you better? "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted May 15 Author Share Posted May 15 Can anyone tell me if you can experience withdrawal symptoms while still taking an SSRI? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 15 Author Share Posted May 15 Has anyone experienced withdrawal symptoms while still taking SSRI'S? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 16 Author Share Posted May 16 Started Effexor 150mg in June 2000 for depression and anxiety. Tried numerous times to taper off Effexor without success due to severe withdrawals. Experienced Effexor tolerance (poop out) around May 2012 Started Sertraline 150mg in May 2013 and tapered off Effexor without withdrawals. Experienced Sertraline poop out around January 2016. Started Mirtazapine 30mg around July 2016. Was on both Sertraline and Mirtazapine until I started to become depressed and very anxious around March 2019. Tapered gradually off Mirtazapine without withdrawals around February 2019 Tapered very gradually off Sertraline June 2020 without withdrawals. Been depressed and very anxious since March 2019. Admitted to hospital for ECT October 2022. No response from ECT. Readmitted to hospital January 2023. Started Agomelatine March 2023 which is a non SSRI. Continue to feel depressed and very anxious. Also been on diazepam at a low dose for a few years on a weekly prescription. In addition been on Pregabalin 600mg for about 3 years. Since being admitted to hospital in October 2022 been on Zopiclone 7.5mg. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 16 Author Share Posted May 16 I've now entered my drug and tapering history as requested. Having read many of the articles on the site I have come to the conclusion that what I have been calling 'Tardive Dysphoria ' is actually protracted SSRI withdrawal. I was on SSRI/SNRI's for 20years. I came off all antidepressants in 2020. But then started on Lithium to which I had no response and came off because of fears of the potential serious side effects. After that I tried Trazodone in the hope that it would help me sleep and take away the dreadful feelings of anxiety and low mood. I reacted badly to the Trazodone and came off it within a few weeks. In October 2022 I became suicidally depressed and was admitted to hospital for a course of ECT. Had no response to the ECT. Was readmitted to hospital in January 2023 and was put on Agomelatine 25mg at night. Been on this for about 2 months with no real improvement in my symptoms. My current medication is Agomelatine 25mg at night: Pregabalin 200mg 3 times daily: Olanzapine 7.5mg at night and diazepam 10mg daily. My psychiatrist is further reducing my Olanzapine from 7.5mg to 5 mg. I don't really know where to go from here. I would really like to stop all these psychotropics which have been added over the years due to misdiagnosis. Any suggestions on where to start would be greatly appreciated. Also would like to ask if what I have is indeed Protracted SSRI withdrawal? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator FireflyFyte Posted May 16 Moderator Share Posted May 16 51 minutes ago, Peter23 said: My psychiatrist is further reducing my Olanzapine from 7.5mg to 5 mg This is a very large drop and goes against the standard advice here of dropping no more than 10% per month. Olanzapine is notoriously difficult to taper off from so would recommend smaller drops in dose to try and prevent further withdrawal symptoms especially when you are in a sensitive state. Pre- October 2022: Wellbutrin, Escitalopram, Citalopram, Sertraline, Adderall IR, Vyvanse, Propranolol, Buspar, Ativan, and Latuda Oct 13, 2022 - Oct 24, 2022 and Oct 31, 2022 - Present: Zyprexa (2.5 mg). Jan 14, 2023 -> Began transition to liquid suspension. Jan 29, 2023 = 2.375mg -> Feb 12, 2023 = 2.25mg -> Feb 27, 2023 = 2.14mg -> Mar 12, 2023 = 2.025mg -> Mar 27, 2023 = 1.93mg -> Apr 10, 2023 = 1.82mg -> Apr 23, 2023 = 1.74mg -> May 7, 2023 = 1.64mg -> May 21, 2023 = 1.56mg -> June 4, 2023 = 1.48mg -> June 19, 2023 = 1.4mg -> July 2, 2023 = 1.33mg -> July 16, 2023 = 1.26mg -> July 31, 2023 = 1.2mg -> Aug 13, 2023 = 1.14mg -> Aug 27, 2023 = 1.08mg -> Sep 13, 2023 = 1.02mg Oct 14, 2022 - Present: Prozac (40mg) upped from 20mg on Nov 1, 2022. Oct 31, 2022 - Present: Gabapentin (300mg 3x day) -> May 3, 2023 = 300mg 2x day -> Oct 1, 2023 = 570mg -> Oct 15, 2023 = 540mg -> Oct 29, 2023 = 510mg -> Nov 13, 2023 = 484mg -> Nov 27, 2023 = 460mg Link to comment
Moderator Onmyway Posted May 16 Moderator Share Posted May 16 Hi @Peter23, I have merged three new topics you started - pls remember that you only get ONE introductions topic on SA. Please keep your posts about your case to this one thread. Thank you for filling in your drug signature. You asked in another thread if you could have withdrawal effects while on and SSRI effects. 1. You can have adverse effects to a drug you are taking that look like withdrawal. 2. You can have withdrawal effect to a drug you stopped while taking another drug that you started 3. You can have hypersensitivity side effects if you have previously started/stopped drugs when you start a new drug 4. Withdrawal effects can emerge months after you have stopped your drugs It is unfortunately that you have an ECT because there is no evidence from good RCTs that shows that ECT cures anything and I suspect that you were given all these new prescriptions because you were in hospital - sounds like a traditional hospital cocktail in the US. Where to from now? If you want to come off of your drugs we recommend a slow taper of no more than 10% of your previous dose every 4 weeks. Here is a thread with a bunch of links to other threads related to tapering. I would advise you to read them carefully before you start tapering. https://www.survivingantidepressants.org/topic/300-important-topics-in-the-tapering-forum-and-faq/ You will also need to learn to manage your emotions - you can do that by doing CBT, meditation, following Claire Weekes method or any other method that works for you. This is going to be a rocky ride given that you are already not feeling well. But feelings change and you will eventually heal. As long as you remember that you can get through this. One of the biggest lessons I had to learn was that not feeling good for a while is actually not that important in the grand scheme of things. I know it sounds silly - it does feel awful but in the end it will change and you will be OK through it. Our feelings, as strange as it sounds, are not the most important thing. I am not saying this to say that your feelings in particular are not important but that no feelings are that important especially in withdrawal. T Especially in withdrawal they are not indicative of anything - i.e. they do not help us navigate the world - they are just distorted. When not in withdrawal anger may mean that your values have been violated and you need to stand up for yourself. In withdrawal, however, anger comes from withdrawal. The same goes for suicidal feelings and for anxiety and all. This is similar to phantom pain with amputated legs - the amputated part of the leg may hurt but there is nothing there to actually hurt, it is our brain playing tricks on us. OMW "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted May 17 Author Share Posted May 17 Thank you Onmyway for your advice. Sorry for starting several topics. I wasn't sure how the site worked to begin with. I should explain that I forgot to list Olanzapine and Pregabalin in my drug history. When I was taking Effexor I became hypo manic during the early phase of taking it. I was then diagnosed as having Bipolar II disorder. I have been on and off it for many years. At one point I was on 20mg which is the maximum dose. I have come down to 7.5mg over a period of many months. Later on the psychiatrist changed her diagnosis to recurrent depression. Then when my antidepressants stopped working in 2019 she diagnosed me with Generalised Anxiety disorder and put me on Pregabalin which I have been on every since. Sorry for missing this out in my drug history. Is there a way to edit the history? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 17 Author Share Posted May 17 Can I ask why I developed anxiety and low mood while taking two antidepressants Sertraline and Mirtazapine? Is this poop out? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 18 Author Share Posted May 18 Having real struggle today due to awful anxiety and worry combined with lack of motivation and fatigue. Would like to stop the Agomelatine 25mgs as it's making my anxiety much worse. It causes an increase in noradrenaline which produces anxiety However it only comes in 25mg and 50mg tablets. I don't want to risk trying to half a tablet as this would be a 50% reduction. The patient information states that there is no withdrawal with Agomelatine. I don't believe that for one minute from my previous experience with antidepressant dose reductions. Any suggestions would be very welcome. Thanks. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted May 18 Moderator Share Posted May 18 Hi @Peter23, please read the links under the link I posted earlier with FAQ on tapering - cutting in half or stopping are both not recommended by SA protocol. Right now you need stabilization, not more tapering. When you are ready, taper no more than 10% of the previous dose of only ONE drug. Starting/stopping things makes your system even more sensitized. Can you, please, try to reformat your drug history similar to mine? We need to see at each point in time on what drugs you were and especially the last two years and now. OMW "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted May 18 Author Share Posted May 18 I have removed my drug and tapering history in order to reformat it. Could you please remind me how to enter my drug history. Thanks. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 18 Author Share Posted May 18 Sorry Onmyway but I seemed to have deleted not only my own drug history but yours and that of everyone else who has replied to my post. How do I reverse this? Thanks. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted May 18 Moderator Share Posted May 18 It's linked in a post earlier. "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted May 19 Author Share Posted May 19 Sorry could you direct me to the earlier link to reinstate my drug history. Thanks 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 21 Author Share Posted May 21 Saw a new psychiatrist on Friday. She wants me to cross taper from Olanzapine 7.5m to Quietipine to help with my severe persistent anxiety. Tried to tell her I wasn't sure about switching medication. Really concerned that it will make me feel worse. Going to call my GP to talk to him about the change of medication. Also worried that my GP will half my dose of zopiclone 7.5mg that I have been on for the past 5 months. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted May 22 Author Share Posted May 22 Really struggling with lack of motivation severe anxiety and fatigue. I have been suffering all of this since March 2018 when my antidepressants stopped working. Don't know how much longer I can go on feeling like this. Been really pushing myself to do things over the past few weeks but seem to have hit the buffers today. Any advice would be much appreciated. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted May 22 Moderator Share Posted May 22 On 5/19/2023 at 10:55 AM, Peter23 said: Sorry could you direct me to the earlier link to reinstate my drug history. Thanks Peter, we are volunteers here and do not have the capacity to spoon feed this information to this extent - you can scroll back and find the message with the link and then read the information under the links. We all have jobs, families, our own withdrawal. These are simple tasks. If you are not able to read previous messages perhaps you would be better served in a different format. We can provide you help in terms of coming off of your drugs in the least harmful way but we don't have the skills/powers to help with depression despite how much it breaks our heart to see people suffer. It seems like from all the treatments and changes and the ECT your nervous system has been put through the wringer and what it needs right now is calm and stability - an opportunity to reset itself back to normal slowly. I would not make any changes right now. We really don't know much about agomelatine here. We'd advise to taper it down at 10% of your previous dose every 4 weeks like other psychiatric drugs but it seems like it also is creating significant side effects for you. To disentangle what is what can you pls post daily notes like explained here and post them every day in your intro topic. It will help us understand your symptom pattern better and advise with more information on Agomelatine. Thanks. OMW "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Peter23 Posted May 23 Author Share Posted May 23 Thanks for your reply. I do understand that you are volunteers and have lives and problems of your own. I have been trying to read as much as possible on the site and will go back and re read the links you kindly gave me. I find it very difficult to concentrate on reading and retaining information probably due to the ECT. I can't find a doctor who understands protracted antidepressant withdrawal and all they seem to want to do is prescribe me different medications. I agree with you that what I need is a period of stability. My situation is being exacerbated by the side effects of Agomelatine which are anxiety, agitation, nausea, abdominal pains, anorexia all of which are worse in the morning. The Agomelatine apparently causes an increased release of noradrenaline which causes a flight or fright response. I am doing my best at the moment to push myself despite these symptoms. I have also started to re read Claire Weekes book on overcoming anxiety. I apologise for perhaps expecting too much from you and from this site. I really do appreciate the time you are giving me. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Moderator Onmyway Posted May 23 Moderator Share Posted May 23 (edited) @Peter23 happy to help with personalised advice but need cooperation with reading links as much as you can. Can you get someone to help you understand and make decisions? If you post symptom diaries in the requested format we may be able to help decide if you need to stop or go off of Agomelatine faster. To help with cortisol issues try magnesium (avoid mag oxide bc of stomach issues) and vitamin C. Omw Edited May 23 by Onmyway "Nothing so small as a moment is insurmountable, and moments are all that we have. You have survived every trial and tribulation that life has thrown at you up until this very instant. When future troubles come—and they will come—a version of you will be born into that moment that can conquer them, too." - Kevin Koenig I am not a doctor and this should not be considered medical advice. You can use the information and recommendations provided in whatever way you want and all decisions on your treatment are yours. In the next few weeks I do not have a lot of capacity to respond to questions. If you need a quick answer pls tag or ask other moderators who may want to be tagged. Aug 2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg, xanax prn, wellbutrin for a few months, trazodone prn Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used) Aug 2018 - citalopram 40 mg (self titrated up) September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0 Feb 2019 0.25 xanax - 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week (off by 4/14/19- no tapering) citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg, 7/27/19 -1.5 mg, 8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!), 10/8/21 - 0.9, 10/18/21 - 0.875, 12/31/21 - 0.85, 1/7/22 - 0.825, 1/14/22 - 0.8, 1/22/22 - 0.785, 8/18/22 - 0.59, 12/15/2022 - 0.48, 2/15/22 - 0.43, 25/07/23 - 0.25 (mistake), 6/08/23 - 0.33mg Supplements: magnesium citrate and bi-glycinate Link to comment
Moderator Emeritus Carmie Posted June 2 Moderator Emeritus Share Posted June 2 How are you doing @Peter23💛 Been on APs, benzos, ADs and opiates, for chronic pain. Had Akathisia in the past that made me suicidal. Still on Seroquel. 2019:➡️ March10=7.25mg ✔️ April17=7.0✔️ June5=6.75✔️ July14=6.50✔️ Aug28=6.25✔️ Oct10=6.20 ✔️ Oct21=6.0✔️ Dec16=5.80 ✔️ 2020➡️ Jan 21=5.60 ✔️ April2=5.40 ✔️ May29=5.20 ✔️ Aug14= 5.0 ✔️Sep29=4.80✔️2021➡️ Jan31=4.60 mg✔️ April24=4.40mg✔️Jul17=4.30mg ✔️ Aug 28=4.20 ✔️ Oct 11=4.15✔️Nov1=4.10 ✔️ Nov21= 4.05✔️ Dec13= 4mg ✔️2022 ➡️ Jan8=3.95✔️ Jan31=3.90✔️ March2=3.85 ✔️ April4=3.80 ✔️ June16=3.75✔️ July26=3.70✔️ Sep2=3.65✔️ Oct21=3.60 ✔️ Dec8=3.55✔️2023➡️ Jan 26=3.50✔️ March 17=3.45✔️ June12=3.40✔️ July30=3.35✔️ Sep14=3.30✔️ Oct31=3.25✔️This is NOT medical advice.Consult your doctor. Link to comment
Peter23 Posted June 4 Author Share Posted June 4 Hi Carmie thanks for your message. I'm still suffering from severe anxiety due to the antidepressant Agomelatine. Started taking magnesium as advised by one of the monitors on the site. Just taking things a day at a time. How are you doing? 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
Peter23 Posted June 7 Author Share Posted June 7 Continue to experience significant anxiety and depression. Recently started magnesium to help with the anxiety. Also started taking L Theanine which has been shown to help with both anxiety and depression. Been trying to improve my diet to include foods high in vitamin c. Trying to use breathing exercises for severe anxiety attacks in the morning. Spoke to my GP about the Agomelatine and how it has increased my anxiety. Waiting for an appointment with a new psychiatrist to discuss gradually tapering the Agomelatine. Had a better day yesterday but not so good today. Trying to use CBT techniques to challenge my negative thinking. Considering taking another course of CBT. Need to keep pushing myself a day at a time. 2000-Venlafaxine 150 mg and Olanzapine 10 mg started 2012- Venlafaxine(tapered off) to Sertraline 150 mg until 2021, added mirtazapine 30 mg until 2019 2018-2023, Oct- Pregabalin, started 150 mg to 600 mg 2019- Diazepam started 6mg 2022- July-restart mirtazapine(unsuccessful) Oct- ECT X 12, Zopliclone 7.5 mg start- present 2023- January, olanzapine decreased to 7.5 mg, Lorazepam 1 mg X 2 weeks, Diazepam increased- 20 mg, some tapering to June-Diazepam 10 mg March- Agomelatine added-25 mg October 9th, 2023 present meds bolded Link to comment
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