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DinaDina: overactive/painful bladder, PGAD? after sertraline


DinaDina

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Hi everyone!

I’m not a native English speaker but I’ll try to write my story.

 

I was taking Zoloft (Sertraline) and one Russian antipsychotics drug for 3 weeks. 2 weeks - 12,5 mg of Zoloft. 1 week - 25 mg. Then I got an overactive and painful bladder. I didn’t know what happened with me. It wasn’t UTI because of good tests. I cancelled cold turkey all of drugs. And my bladder became ok over 3-4 days. My psychiatrist insisted that I needed to figure out which drug was caused an overactive bladder. I trued one pill of antipsychotics and my bladder became overactive again. I immediately cancelled it and my bladder became ok again. A psychiatrist said that I had an negative reaction to this antipsychotic so I had to cancel it and continue treatment by Zoloft.

 

I was so stupid and believed a psychiatrist. After returning Zoloft (12,5 mg) me bladder became overactive and painful again. I don’t know why 2 different types of drugs were caused problems with a bladder.

 

I immediately stopped taking Zoloft. It seemed that my bladder was getting better but 3 days later I felt a strong spasm in my bladder, lower abdomen, back, sides. IT WAS AWFUL. My bladder was became overactive and painful again. I wanted to urinate really all time. It was a month ago.

 

Of course my psychiatrist said that all of these were symptoms of neurosis. She said that I had to take another drugs but I refused.

 

When my bladder became less overactive, I started to feel something strange. Maybe it’s in a clitoris, maybe it’s in an urethra. I want to urinate and feel arousal at the same time. I have a feeling of urine in my urethra. When I change my position I feel as if something is overflowing in my urethra.

 

I don’t know I have PGAD or smth else. I think it’s not a clitoral sensitivity, I feel arousal a little bit higher than clitoris and on my right side. And I have a normal sensitivity on my left side. I'm able to orgasm very quickly and it does not bring relief and sometimes makes it even worse.


I have many WD symptoms now but painful bladder and PGAD are the main. I’m so scared. I read many posts about PGAD and problems with bladder here and I just need some more hope.

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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  • Administrator
Altostrata

Welcome, @DinaDina

 

It does sound like you got PGAD from those drugs. Since you were taking them a short while, you probably will see very gradual improvement over some number of months.

 

If I were you, I would avoid psychiatric drugs in the future and pursue non-drug treatments instead.

 

In general, many people find fish oil and magnesium supplements helpful, see


https://survivingantidepressants.org/index.php?/topic/36-king-of-supplements-omega-3-fatty-acids-fish-oil/


https://survivingantidepressants.org/topic/15483-magnesium-natures-calcium-channel-blocker/

 

You might try a little bit of one at a time to see how it affects you.

 

Please let us know how you're doing.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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10 hours ago, Altostrata said:

If I were you, I would avoid psychiatric drugs in the future and pursue non-drug treatments instead.

 

I WILL. Thank you.

 

I hope that I will get better but I have bad days now

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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Just an update about my symptoms after 6 weeks of stopping Zoloft

 

  • Bladder pressure (I can’t sleep on my belly)
  • Feel the urge to urinate in the right side of clitoris (sounds crazy)
  • Very sensitive area of clitoris. I can orgazm very quickly and without enough relief
  • Pain in lower abdomen (especially on the right)
  • Pain in the sides (near the low back)
  • Lower back pain and pain in the right thigh randomly come and go away

 

If anybody have/had PGAD or bladder issues after AD I will appreciate to read about your experience and symptoms 

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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Overactive bladder is known side effect of Sertraline. It is even mentioned in the package leaflet.

I'm dealing with that too, but I cannot quit Sertraline unfortunately.

2013 - 2018 various ADs, last and for the longest period was Brintellix

1/2019 - 6/2019 Olanzapine 5mg CT no issues

2019 - 7/2020 Venlafaxine 150mg CT

 

9 - 10 /2021 - shortly back on Venlafaxine

10/2020 - 12/2020 Olanzapine 5mg CT

12/2020 - Sertraline 50mg

1/2021 - added Agomelatine 25mg

currently, dealing with insomnia, anxiety, depression probably related to the Olanzapine withdrawal.

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Hi jipavl, I'm so sorry that you're dealing with it. I stopped Zoloft because of developing overactive bladder and without Zoloft my bladder became ok but 3 days later bladder pain and frequency returned with a new force

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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I'm coming to the tailend of my experience with this. Mine came on several months after getting off Paxil of 10years.

 

I had the urge to urinate 24/7, pressure, strange sensations, feeling of urine stuck in my urethra, pain. All tests were negative and eventually some symptoms started to drop off. I'm now in and out of frequent urination but mostly don't think about it. I never thought it would end but it has improved so much. I believe there is a secondary fear going on with it as well due to the experience. If I worry and start giving it attention it can start up and it cascades from there.

 

I honestly thought I was going mad and no one seemed to understand.

 

Keep going, it will settle down.

April 2007 -  Seroxat 20mg

August 2008 - Cold Turkey

August 2009 - Cold Turkey

November 2009 - Reinstatement adverse reaction akathesia/suicidal/anxiety

March 2011 - Start taper

November 2012 - Crash badly at 1.25mg akathesia/suicidal/extreme anxiety

January 2013 - 5mg Seroxat, 300mg  Lyrica

April 2017 - Successfully get off Seroxat with taper followed by 4 month of withdrawal 

January 2018 - Start with constant urinary urge/pain/burning/genital sensations 2 week after anxiety/akathesia ends

January 2019 - Started reducing Lyrica as I suspect it's causing frequent urination, tinnitus, fatigue, brain fog and mental decline.

December 2019 - Off all pysch meds

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Boris thank you for your support and sharing your experience.

 

It seems I’m going mad with this symptoms. They change with time but it doesn’t receive a relief. All of my tests are negative too. But I didn’t do a cystoscopy (I know that you did) because my urinary symptoms and mental symptoms appeared at the same time. That’s why I’m sure that it’s WD. Though if I even have IC what I can do. IC «treat» by amitriptyline and I don’t want to take any ads. 

 

I hope you'll get better and better!

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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  • Moderator
manymoretodays

Hi DinaDina,

And welcome aboard.

And that is so common, to feel like you are going mad with symptom(s).

I don't know if this will help or not, but it IS fairly common:

Health anxiety, hypchondria and obsession with symptoms

 

And I'm hoping that, like most here, you will begin to have some really nice windows soon

The Windows and Waves Pattern of Stabilization

 

And best, Love, peace, healing, and growth,

manymoretodays(mmt)

Started with psycho meds/psychiatric care circa 1988.  In retrospect, and on contemplation, situational overwhelm.

Rounding up to 30 years of medications(30 medication trials, poly-pharmacy maximum was 3 at one time).

5/28/2015-off Adderal salts 2.5mg. (I had been on that since hospital 10/2014)

12/2015---just holding, holding, holding, with trileptal/oxcarb at 75 mg. 1/2 tab at hs.  My last psycho med ever!  Tapered @ 10% every 4 weeks, sometimes 2 weeks to

2016 Dec 16 medication free!!

Longer signature post here, with current supplements.

Herb and alcohol free since 5/15/2016. 

None of my posts are intended as medical advice.  Please discuss any decisions about your medical care with a knowledgeable medical provider. manymoretodays

 

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Hi manymoretodays. Thank you for your message.

 

It is hard not to obsess about something as PGAD and constant feeling urge to urinate. I’m so tired and desperate. I don’t know how people live with it for years. I’m not so strong. PGAD is absolutely the worst thing.

 

7 weeks after stopping Zoloft.

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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I notice that I usually have the strongest symptoms of PGAD/bladder when I get out of a bed in the morning. Meanwhile I feel almost fine when I just wake up and lie on a bed. But when I get out of a bed, the process seems to start and it gets better (only better, not fine) in the evening.

 

It’s just a thought. But maybe it is as a good sign? 

 

I also sometimes feel a severe anxiety when I wake up and it continues until I get out of a bed. So funny: when I wake up and continue to lie, I feel an anxiety but a bladder issues and PGAD are tolerable; when I get out of a bed, an anxiety decreases and bladder issues and PGAD increase.

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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I found something similar with my urinary issues. Most of the time the mornings would be better so I would try stay there as long as possible. Obviously with work I had to move at some point  As I got up it would start getting worse and peak around 5-7pm then I'd be exhausted and the evening might be better.

 

My long experience with anxiety/Akathisia was the opposite. Mornings would be what I consider to be an absolute sh*t show while evening around 6pm would be much calmer.

 

So going back to urinary I do suspect a lot of it is down to the pelvic floor. My sub pubic area and around the bladder would feel so tense and actually flutter at times like the muscles were in spasm. I've had something similar in my upper back that caused all kinds of arms and hand nerve issues. Good news that cleared up and ironically thats what got me on these meds in the first place.

 

I'll keep telling you I didn't think I'd get better but I have improved. You will as well.

 

 

April 2007 -  Seroxat 20mg

August 2008 - Cold Turkey

August 2009 - Cold Turkey

November 2009 - Reinstatement adverse reaction akathesia/suicidal/anxiety

March 2011 - Start taper

November 2012 - Crash badly at 1.25mg akathesia/suicidal/extreme anxiety

January 2013 - 5mg Seroxat, 300mg  Lyrica

April 2017 - Successfully get off Seroxat with taper followed by 4 month of withdrawal 

January 2018 - Start with constant urinary urge/pain/burning/genital sensations 2 week after anxiety/akathesia ends

January 2019 - Started reducing Lyrica as I suspect it's causing frequent urination, tinnitus, fatigue, brain fog and mental decline.

December 2019 - Off all pysch meds

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7 hours ago, Boris said:

I'll keep telling you I didn't think I'd get better but I have improved. You will as well.

 

I need to hear it all the time. Thank you. You're so kind. 

 

7 hours ago, Boris said:

Most of the time the mornings would be better so I would try stay there as long as possible. Obviously with work I had to move at some point  As I got up it would start getting worse and peak around 5-7pm then I'd be exhausted and the evening might be better.

It definitely sounds like our CNS wakes up with us. I think this condition can't be IC (I'm still afraid that it's IC or something else "real", which doesn't have a treatment).

 

Did strange sensations in your genitals go away too?

I absolutely hate it. I feel it like the urge to urinate and the arousal at the same time. I think I have this feelings because the female urethra and the clit are close together. That's why I do think that all my problems come from my bladder and urethra. 

 

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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4 hours ago, DinaDina said:

I need to hear it all the time. Thank you. You're so kind. 

 

It definitely sounds like our CNS wakes up with us. I think this condition can't be IC (I'm still afraid that it's IC or something else "real", which doesn't have a treatment).

 

Did strange sensations in your genitals go away too?

I absolutely hate it. I feel it like the urge to urinate and the arousal at the same time. I think I have this feelings because the female urethra and the clit are close together. That's why I do think that all my problems come from my bladder and urethra. 

 

 

Yes the strange sensations were one of the first to go and with the intensity of pressure etc, this was after the major pain. For me being male I felt it at the end and was constantly trying to urinate it out. I just read someone else describe it as restless leg syndrome but in the genitals.  The strange sensations and pressure were by far the most distressing for me. Working from home I would work for 5mins then pace and squeeze, sit on hot water bottles, ice, sit in the bath, anything. Sometimes I get a flutter of it now but it is fleeting.

 

I never realised I might of had PGAD as I didn't have  what I thought was the arousal part but masturbation was the only break I could get from it, that stopped all the feelings but it would come back shortly after. 

 

IC is even being re classified here in the UK as they reckon true IC is very rare and people are misdiagnosed. There seems to be a lot of confusion medically down there. As soon as I ruled IC out my symptoms improved which was probably the extra stress I was giving myself. I was diagnosing myself with all sorts to be honest.

 

I was on Paroxetine 10 years by the end of the taper so I'm confident you will a more rapid recovery.

April 2007 -  Seroxat 20mg

August 2008 - Cold Turkey

August 2009 - Cold Turkey

November 2009 - Reinstatement adverse reaction akathesia/suicidal/anxiety

March 2011 - Start taper

November 2012 - Crash badly at 1.25mg akathesia/suicidal/extreme anxiety

January 2013 - 5mg Seroxat, 300mg  Lyrica

April 2017 - Successfully get off Seroxat with taper followed by 4 month of withdrawal 

January 2018 - Start with constant urinary urge/pain/burning/genital sensations 2 week after anxiety/akathesia ends

January 2019 - Started reducing Lyrica as I suspect it's causing frequent urination, tinnitus, fatigue, brain fog and mental decline.

December 2019 - Off all pysch meds

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14 hours ago, Boris said:

IC is even being re classified here in the UK as they reckon true IC is very rare and people are misdiagnosed. There seems to be a lot of confusion medically down there.

 

 I agree about IC. There is the opposite story in Russia. If doctors can't find something they diagnose IC. It's like chronic pelvic pain here.

 

14 hours ago, Boris said:

I never realised I might of had PGAD as I didn't have  what I thought was the arousal part but masturbation was the only break I could get from it, that stopped all the feelings but it would come back shortly after. 

 

Masturbation makes me feel worse because after that arousal increases. It's awful :( 

 

 

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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I'm terrified but my PGAD is getting worse and worse. Today I woke up at 4 am because of new clit sensations. Like twitching and tingling. I couldn't continue to sleep. And while I was trying to sleep again, very strong arousal came and my clit became too heavy. It looks like how I need push something out but I can't. At the same time it seems that my bladder issues are getting better. I have a window without pain and strong bladder pressure now (I have pressure but it's really mild). But this arousal...

 

Sorry for TMI but maybe it helps somebody with similar symptoms. 

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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PGAD is awful. I really want to die. I always love my life but I’m surviving now. I feel how doctors ruined my beautiful life. They said me that only AD helped me with my stomachache. They said that my ache was only inside my head. I didn’t want to take AD but I believed them. And I’m in absolutely bad place now. Moreover, I understand that it could get worse.

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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On 2/26/2021 at 9:15 AM, DinaDina said:

PGAD is awful. I really want to die. I always love my life but I’m surviving now. I feel how doctors ruined my beautiful life. They said me that only AD helped me with my stomachache. They said that my ache was only inside my head. I didn’t want to take AD but I believed them. And I’m in absolutely bad place now. Moreover, I understand that it could get worse.

 

I was given anti depressants to deal with arm pain I was having from doing my degree course. Then they tell you it's your original condition coming back when you're in withdrawal.

 

It will level and ease off at some point we just don't know when that will be. I use to get a hot water bottle or frozen peas and sit with them squeezed between my legs to try alter the sensation. I'd have several baths a day while working from home which would give me a break. Also lying on my front on the floor stretching out my pelvic region.

 

It's good news your bladder area is calming.

April 2007 -  Seroxat 20mg

August 2008 - Cold Turkey

August 2009 - Cold Turkey

November 2009 - Reinstatement adverse reaction akathesia/suicidal/anxiety

March 2011 - Start taper

November 2012 - Crash badly at 1.25mg akathesia/suicidal/extreme anxiety

January 2013 - 5mg Seroxat, 300mg  Lyrica

April 2017 - Successfully get off Seroxat with taper followed by 4 month of withdrawal 

January 2018 - Start with constant urinary urge/pain/burning/genital sensations 2 week after anxiety/akathesia ends

January 2019 - Started reducing Lyrica as I suspect it's causing frequent urination, tinnitus, fatigue, brain fog and mental decline.

December 2019 - Off all pysch meds

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8 hours ago, Boris said:

I was given anti depressants to deal with arm pain I was having from doing my degree course. Then they tell you it's your original condition coming back when you're in withdrawal.

 

The same story. When my bladder became overactive while I was taking Zoloft my doctor told me it was neurosis developing and with my stomachache added bladder issues - «It’s so common when people with neurosis have overactive bladder». I’m happy that I didn’t believe her and didn’t take another meds. But it’s pity it didn’t help me a lot.

 

 

Last night my bladder issues came back (I had a 10 days window without strong pain). I feel pain in lower abdomen, can’t lie on belly and want to urinate more intense again. But PGAD symptoms are tolerant now. 

 

I feel that my genital area (especially urethra) is wet but it’s not true, it's just my feelings. Sometimes an air bubble come out from my urethra. It all sounds absolutely crazy. Month ago I stopped to look for a doctor who will be able to understand me. I’m just waiting.

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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2 months after stopping Zoloft

 

I’m crying all day. Pain went away again and PGAD is strong now. I don’t know how live with it and can’t relief myself. I can’t do anything. I feel so helpless, hopeless and useless. 

25 November 2020 - 22 December 2020 - Zoloft (3 weeks - 12.5 mg, 1 week - 25 mg); 1 January 2021 - Zoloft (12.5 mg)

18-24 December 2020 - Teraligen 2.5 mg-3.75 mg (Russian antipsychotic)

18-28 December 2020 - Eglonil 100 mg (Sulpiride)

 

Supplements: vit D, omega, magnesium

 

Symptoms since stopping Zoloft: overactive/painful bladder, pelvic pressure, PGAD, severe anxiety

 

 

 

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