Fallensoul Posted March 12, 2021 Share Posted March 12, 2021 I'am a guy from the Netherlands who made one mistake which caused unforseeing consequenses from a kaliber man can' t imagine. Medio 1998 I decided to take Seroxat 20mg on advice of my familydoctor after I had some sort of burnout. Slowy but cleary the tension and stress lifted and energie came back and I thougt my recovery was near. Wrong! I was able to get an early peek what antidepressants can do in a wrong way. I developed breathing Ocd, ounce a time when lying in bed. This set me back for weeks, trapped in repeated toughts about not letting loose my beathing, awful. I finally got over it when the medication did its work and from that I had a no issues anymore and a problemfree period of 20 years. I have tried to come off in 2011, but after a month no sleep and moodproblems, when I was at arround 5mg, I reinstate to 20mg. Again breathing Ocd during beginning! Again the medication worked and I could fynally sleep. From that time I again I had 7 wonderfull years. In 2018 I got problems with sleep agan and also problems with neck and back muscles. And then in aug. 2018 hell broke loose, in a few days I got anxiety and panic attacks in a way I couldn't imagine they excists. I immediatly thought about seroxat not working anymore, and the dose was upped to 30mg. Bad mistake, I became even more crazy, and didn't sleep at all anymore. So I tapered back to 20mg, while suffering all type of mental problems, terrible mood, anxiety, panic attacks, emotional broken to the bone etc. After that time I contacted mental help and tried several medications, but only buspar addition worked in less then 10 days, I was the happiest person on earth, but it stopped working after 4 weeks. In oct. 2020 I was set on a low dose Clomipramine and began to taper the Seroxat. I have had builded up the clomipramine to 50 mg, but never felt right, besides very short moments in the evening, but the rest of the day stil felt like madness, restless, anxious, emptyness, depressed and so on and mr. breathing ocd is allways arround the corner. Since 2 weeks I stopped smoking as it stressed me even more and began tapering the clomipramine. I'm on 35mg now and 6 mg Paroxetine see sig. Last 3 weeks there is a change in sympthoms, anxiety and panic have subseeded, but tiredness, has filled the gab along with the ever gooing on lack of motivation and lowmood/lack of happyness or emptyness. Is this the last phase of seroxat withdrawal? I'm not a depressive person at all and have energie like a Terminater normal. Yesterday I forgot to take the Clomipramine and felt much better! I allmost wanted to Ct the clomipramine, but that wouldn't wise I think, Im allready on it for 5 months, so I decided to go to 30mg at ounce at try to use a quick taper Are my issues familiar? Is it seroxat withdrawal? I gonna taper the Seroxat with 5% in month hoping to get my live back after this 2,5 year hell. Any suggestions are very welcome, as I absoluty dont't know what the future have in store me. Btw, I take magnesium citrate, vit. C, omega 3-6-9, gaba, tyrosine and lithium orotate. Edward. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 13, 2021 Author Share Posted March 13, 2021 (edited) I'm also wonder where the fatique is coming from. In the evening it goes away a bit. I take the Seroxat arround 17u, 6mg, and the Clomipramine arround 23u. Is it the seroxat depleted the next day due the smal dose metabolised completely after that time? Whats wise , first tapering the Seroxat or the Clomipramine? Maybe the Clomipramine still works, but Seroxat withdrawal is slamming through it? In that case Seroxat tapering should be prevale? But what about the fact that I felt much better after I forgot one dose Clomipramine? Please help to give me some insights. Edited March 13, 2021 by Fallensoul Addition 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Administrator Altostrata Posted March 14, 2021 Administrator Share Posted March 14, 2021 Welcome, Fallensoul. It is unusual for people to take clomipramine and an SSRI such at paroxetine together, as the combination is known to cause an undesirable adverse reaction of serotonin toxicity or overstimulation. On 3/12/2021 at 12:19 PM, Fallensoul said: I'm on 35mg now and 6 mg Paroxetine see sig. Last 3 weeks there is a change in sympthoms, anxiety and panic have subseeded, but tiredness, has filled the gab along with the ever gooing on lack of motivation and lowmood/lack of happyness or emptyness. Not sure what your question might be. It seems to me that withdrawal symptoms from your prior paroxetine tapering have faded and you are now feeling the effects of clomipramine. Lack of motivation and emotional anesthesia are very common adverse effects from both SSRIs and TCAs such as clomipramine. So you might say the drugs are "working" again, but your honeymoon with them is over. Lack of motivation and emotional anesthesia could also be withdrawal symptoms or residue from your paroxetine habituation, when it stopped working and you unsuccessfully increased to 30mg. If you want to continue to go off paroxetine, you probably will want to taper it slowly to avoid withdrawal symptoms. Please see Tips for tapering off paroxetine (Paxil, Seroxat) This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Fallensoul Posted March 15, 2021 Author Share Posted March 15, 2021 Hello Altostrata, thank you for your reply. The Clomipramine was started to cross over from the paroxetine, when the paroxetine was tapered down to 10mg. They said a low dose ofClomipramine wouldn't hurt. But it didn't help much either and finally rose tp 50mg on january gave indeed adverse effects I guess, beceause I felt very restless and emotional more unstable So I tapered fairly quickly down to 30mg now and wait to see of I stabilise a bit and It seems thay way.( The wakeup and few hours after this are still tough) And after this slowly taper further the paroxetine frist. Symthoms are now mostly lack of positive energy, (exhaused) lack of motivation/happyness , easely stresed all in body and mind. Sometimes anxiety and depressed. I will defenetly read all the valuable tips, thanks. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 17, 2021 Author Share Posted March 17, 2021 More and more sympthoms are fatique, no drive/energy to do things, not realy sad, but liveness, feeling empty/dead.. etc. Something I was the opposite of it normally. I mis so much my old drive and enthousiasem. And inside I never want to live more then now.....but the empty shell arround me doesn't do scratch.... OCD, panic, anxity and restnessless are almost gone. Waiting for windows badly. (start to cry when typing this, this so much not me)Feeling no joy when beiing an emotional person (HSP) is so heavy to cope.... Paroxetine on 5,8mg now, Clomipramine on 30mg. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 17, 2021 Author Share Posted March 17, 2021 Now a depressed wave. Is it possible paroxetine withdrawal is slamming through new medication in this case Clomipramine? And i never felt good on Clomipramine btw. I'm in dilemma to taper the Clomipramine right away alomg the paroxetine taper. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus ChessieCat Posted March 18, 2021 Moderator Emeritus Share Posted March 18, 2021 Please do a drug interaction check and copy and paste the results or a link to the results here in your Introduction topic: Drug.com Interactions Checker This is another interaction checker which might provide some more specific information. You cannot paste a link to the results like the other checker. Medscape Drug Interaction Checker 1 * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Fallensoul Posted March 18, 2021 Author Share Posted March 18, 2021 (edited) ChessieCat, I know their interactions, they both increase their levels due the same metabolism genes: https://www.drugs.com/interactions-check.php?drug_list=1800-0,702-0 From medcape: Serious - Use Alternativeparoxetine + clomipramine paroxetine and clomipramine both increase serotonin levels. Avoid or Use Alternate Drug. paroxetine + clomipramine paroxetine will increase the level or effect of clomipramine by affecting hepatic enzyme CYP2D6 metabolism. Avoid or Use Alternate Drug. Monitor Closelyclomipramine + paroxetine clomipramine and paroxetine both increase QTc interval. Modify Therapy/Monitor Closely. Today again allmost braindead, so tired mental and physically. Clomipramine is down to 30mg and paroxetine to 5,8mg. Edited March 18, 2021 by Fallensoul Additions 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 19, 2021 Author Share Posted March 19, 2021 I wonder where the extreme fatique is coming from. First I had 2 years off anxiety, panic, restnessless etc (also during Clomipramine build period to 50mg). and now I sleep 10-12 hours a day, move myself to the couch and lie down till 15u, before there is any life in this brain and body and can manage daily impulses. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 19, 2021 Author Share Posted March 19, 2021 Any others encountered extreme fatique during tapering, and in which fase (beginning, middle or end of the withdrawal symthoms)? 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus Gridley Posted March 19, 2021 Moderator Emeritus Share Posted March 19, 2021 20 minutes ago, Fallensoul said: Any others encountered extreme fatique during tapering, and in which fase (beginning, middle or end of the withdrawal symthoms)? Fatigue is a very common withdrawal symptom (I have it myself) and can occur at any point in the withdrawal process. 1 Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of April 1: 6.8mg Taper is 91% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs. Link to comment
Fallensoul Posted March 19, 2021 Author Share Posted March 19, 2021 11 minutes ago, Gridley said: Fatigue is a very common withdrawal symptom (I have it myself) and can occur at any point in the withdrawal process. Thanks, do you have it every day? I do since a few weeks, I can't do anything but lie down, allthough at the end of the day it gets slightly better. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus Gridley Posted March 19, 2021 Moderator Emeritus Share Posted March 19, 2021 1 hour ago, Fallensoul said: Thanks, do you have it every day? I do since a few weeks, I can't do anything but lie down, allthough at the end of the day it gets slightly better. I have it pretty much every day, though I can get around and do simple things like cook. My fatigue is as more psychological than physical, but exercise is a challenge. Withdrawal takes many, many forms, and you will recover your old self in time. Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of April 1: 6.8mg Taper is 91% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs. Link to comment
Fallensoul Posted March 19, 2021 Author Share Posted March 19, 2021 39 minutes ago, Gridley said: I have it pretty much every day, though I can get around and do simple things like cook. My fatigue is as more psychological than physical, but exercise is a challenge. Withdrawal takes many, many forms, and you will recover your old self in time. I can do simple things, but it costs so effort and energy, mentally and physically. Well I started the medication for fatique and burnout, I hope I wont return to that state. That is also a big thing I fear. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus Gridley Posted March 19, 2021 Moderator Emeritus Share Posted March 19, 2021 9 minutes ago, Fallensoul said: That is also a big thing I fear. Fear takes a lot of energy. It is much better to assume it will work out fine. Your body knows what you are thinking and internalizes it right down to the cell level. Let your system internalize hopeful optimistic feelings and you will be doing yourself a big favor and helping your recovery quite a bit. Attitude is very important. 1 Gridley Introduction Lexapro 20 mg since 2004. Begin Brassmonkey Slide Taper Jan. 2017. End 2017 year 1 of taper at 9.25mg End 2018 year 2 of taper at 4.1mg End 2019 year 3 of taper at 1.0mg Oct. 30, 2020 Jump to zero from 0.025mg. Current dose: 0.000mg 3 year, 10 month taper is 100% complete. Ativan 1 mg to 1.875mg 1986-2020, two CT's and reinstatements Nov. 2020, 7-week Ativan-Valium crossover to 18.75mg Valium Feb. 2021, begin 10%/4 week taper of 18.75mg Valium End 2021 year 1 of Valium taper at 6mg End 2022 year 2 of Valium taper at 2.75mg End 2023 year 3 of Valium taper at 1mg Jan. 24, 2024: Hold at 1mg and shift to Imipramine taper. Taper is 95% complete. Imipramine 75 mg daily since 1986. Jan.-Sept. 2016 tapered to 14.4mg March 22, 2022: Begin 10%/4 week taper Aug. 5, 2022: hold at 9.5mg and shift to Valium taper Jan. 24, 2024: Resume Imipramine taper. Current dose as of April 1: 6.8mg Taper is 91% complete. Supplements: multiple, quercetin, omega-3, vitamins C, E and D3, magnesium glycinate, probiotics, zinc, melatonin .3mg, iron, serrapeptase, nattokinase I am not a medical professional and this is not medical advice but simply information based on my own experience, as well as other members who have survived these drugs. Link to comment
Fallensoul Posted March 20, 2021 Author Share Posted March 20, 2021 You are right about that, but sometimes it's hard to believe one day it will be fine after 2,5 years of missery, but I won't give up hope and will fight this as long as needed. The meds will lose and I gonna taper down, slowly but steady until the poison is cleared 1 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 22, 2021 Author Share Posted March 22, 2021 Could it be that the clomipramine is working, but that the paroxetine withdrawal is slamming through it? I'm deadtired mentally and physically. Or is it the low dose of mirtazipine 3mg, for sleep, which I currenty taper, because I'm not restless and panicly anymore. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 22, 2021 Author Share Posted March 22, 2021 Strange enough, the later in the evening, the less fatique I am. Btw, I'm now on 5,8 mg Paroxetine, should I devide the 10% reduction over 4 times? So 2-2,5 % every week, or is it better to do 10% immediate and wait 4 weeks? 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus ChessieCat Posted March 22, 2021 Moderator Emeritus Share Posted March 22, 2021 On 3/15/2021 at 9:49 AM, Altostrata said: It seems to me that withdrawal symptoms from your prior paroxetine tapering have faded and you are now feeling the effects of clomipramine. Altostrata is SA's founder and has personal experience with psychiatric drugs and has many years of observing the effect of drugs through this website (11+ years) and well as a now defunct website and doing much research. Daily symptom notes can often help with working out what might be happening. If you wish the notes to be assessed please post them here in your Introduction topic. To start with you will need to provide 3 consecutive days. Here is the format which is most helpful for the staff: Keep Notes on Paper 1 * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Fallensoul Posted March 22, 2021 Author Share Posted March 22, 2021 Thanks, will defenetly take a look. I'm in so much clueness, which causing what with 2 medications (I assume 3 mg mirt is not couting as hits only anti histamine receptors in this dose?) 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus ChessieCat Posted March 22, 2021 Moderator Emeritus Share Posted March 22, 2021 I doubt that it hits ONLY histamine receptors. * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Fallensoul Posted March 23, 2021 Author Share Posted March 23, 2021 22-3-2021 9.30u Awake, take 1mg lorazepam feel exhausted, sleep again 12.30u, wake up, feel tired, pain in mucles, no motivation, can't tolerate any impulses from daily live. Take lorazepam 1mg, 2 gabba, 2 tyrosine and 2 lithium orotate, 1 magnesium citrate (pills/supplements advised by my orthomoleculair doctor 12.35u shower 12.50u Eat 2 slices of bread and a cup of green tea 13.00u lying on the couch, feel more dead then alive, low mood 15.30u slowly get some more enery and take some coffee and a smoke. Smoke made temporary happy, but incteased nervousness quickly after. 17.00u, take 1mg lorazepam, and the supplements and the poison, 5,8 mg Paroxetine. 17.05u dinner and watching tv, feel slowly better. 17.45u take a smoke and coffee. 19.30u take orange juice and a smoke, and play/tweaking Skyrim on the pc., smoke dropped mood, and anxiety is lurking on the background 20.30u lying on the couch watching tv, increasing energy, but no happy mood. 22.00u take 0,5mg lorazepam and 0,5 mg Lormetazepam and 2,7 mg Mirtazipine 22.30u, walking the dog. 22.50u, feel at my best during this time, take a smoke or two and do some pc stuff, surfing the web, tweak some Skyrim enb. 0.00u take 28mg Clomipramine and go to bed. 23-03-2021 8.00u, awake, take 1mg lorazepam, feel exhausted bacl to sleep. 12.30 awake, feel exhausted, not happy, force to wakeup pain in mucles, no motivation, can't tolerate any impulses from daily live. Take lorazepam 1mg, 2 gabba, 2 tyrosine and 2 lithium orotate, 1 magnesium citrate 12.35u shower 12.50u Eat 2 slices of bread and a cup of green tea 13.00u lying on the couch, feel a bit more energy, low mood. 14.00u, take some coffee and a smoke, smoke felt not good, no happyness, just emptyness and missery. 14.10u, lying on the couch, depressed. 16.45u take 1mg lorazepam, and the supplements and the poison, 5,8 mg Paroxetine. To be continued. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 23, 2021 Author Share Posted March 23, 2021 17u Dinner and watching TV 17.45u take a smoke and coffee. 20.00 Walking with the dog, energy up, mood down, not a single happy spark, pure emptiness and zero motivation 20.15u take orange juice and a smoke, and try play/tweaking Skyrim on the pc., but I can't set me to it. Smoke, feel so misereable...wondering if I taper the Clomoprimine down along the Paroxetine? I want to be clean so badly, that my body can heal from this evil stuff, crying when memories came up about my passed life. I felt so good all my life, its seems so unreachable, desperetly seeking good vibes in my mind, but there arn't any, crying again, in the last 2,5 years more then in my whole life..will this ever ends... how deep is this rabbithole? 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus ChessieCat Posted March 23, 2021 Moderator Emeritus Share Posted March 23, 2021 Please post a 24 hour period at one time. Also please list the supplements you take, not just "supplements". The supplements also need to be added to your drug signature including the date you started them, the doses and any dates and doses changes please. This allows us to see your drug history at a glance. Thank you. I have notified the other mods that you are keeping daily notes. We have a couple of mods taking time off from SA at the moment so it might be a few days before someone is able to assess your notes. 1 * NO LONGER ACTIVE on SA * MISSION ACCOMPLISHED: (6 year taper) 0mg Pristiq on 13th November 2021 ADs since ~1992: 25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq: 50mg 2012, 100mg beg 2013 (Serotonin Toxicity) Tapering from Oct 2015 - 13 Nov 2021 LAST DOSE 0.0025mg Post 0 updates start here My tapering program My Intro (goes to tapering graph) VIDEO: Antidepressant Withdrawal Syndrome and its Management Link to comment
Fallensoul Posted March 23, 2021 Author Share Posted March 23, 2021 51 minutes ago, ChessieCat said: Please post a 24 hour period at one time. Also please list the supplements you take, not just "supplements". The supplements also need to be added to your drug signature including the date you started them, the doses and any dates and doses changes please. This allows us to see your drug history at a glance. Thank you. I have notified the other mods that you are keeping daily notes. We have a couple of mods taking time off from SA at the moment so it might be a few days before someone is able to assess your notes. Will do. Many thanks for the effort 23-03-2021 8.00u, awake, take 1mg lorazepam, feel exhausted back to sleep. 12.30 awake, feel exhausted, not happy, force to wakeup pain in mucles, no motivation, can't tolerate any impulses from daily live. Take 1mg lorazepam, 2 x 500mg gaba, 2x5mg Lithium Orotate and 2x 500mg L-Tyrosine, 1x400mg magnesium citrate , 1x1000mg vit. C, 1x 15mg Zinc, 2x1mg Molybdeen Glycinate, 2x1000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 12.35u shower 12.50u Eat 2 slices of bread and a cup of green tea 13.00u lying on the couch, feel a bit more energy, low mood. 14.00u, take some coffee and a smoke, smoke felt not good, no happyness, just emptyness and missery. 14.10u, lying on the couch, depressed. 16.45u take 1mg lorazepam, 5,8 mg Paroxetine, 2 x 500mg gaba, 2x5mg Lithium Orotate and 2x 500mg L-Tyrosine, 1x400mg magnesium citrate , 1x1000mg vit. C, 2x1mg Molybdeen Glycinate, and 2x1000mg Omgea 3-6-9 17.00u Dinner and watching TV 17.45u take a smoke and coffee. 20.00 Walking with the dog, energy up, mood down, not a single happy spark, pure emptiness and zero motivation 20.15u take orange juice and a smoke, and try play/tweaking Skyrim on the pc., but I can't set me to it. Smoke, feel so misereable...wondering if I taper the Clomoprimine down along the Paroxetine? I want to be clean so badly, that my body can heal from this evil stuff, crying when memories came up about my passed life. I felt so good all my life, its seems so unreachable, desparetly seeking good vibes in my mind, but there arn't any, crying again, in the last 2,5 years more then in my whole life..will this ever ends... how deep is this rabbithole? 22.00u take 0,5mg lorazepam and 0,5 mg Lormetazepam and 2,7 mg Mirtazipine, 2 x 500mg gaba, 2x5mg Lithium Orotate and 2x 500mg L-Tyrosine, 1x400mg magnesium citrate , 1x1000mg vit. C and 2x1mg Molybdeen Glycinate, 22.30u, walking with the dog. 22.50u, again like every time, mood lifts, take a smoke or two and do some pc-stuff, surfing the web, tweak some Skyrim enb. 0.00u take 27mg Clomipramine and go to bed. Note, can't edit former field(s) anymore, supplements mentioned in this field are correct. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 24, 2021 Author Share Posted March 24, 2021 24-03-2021 9.20u, awake, take 1mg lorazepam, feel exhausted back to sleep. 12.45 awake, feel very exhausted, force to wakeup pain in mucles, can't tolerate any impulses from daily live, but not so depressed. Take 1mg lorazepam, 2 x 500mg gaba, 2x5mg Lithium Orotate and 2x 500mg L-Tyrosine, 1x400mg magnesium citrate , 1x1000mg vit. C, 1x 15mg Zinc, 2x1mg Molybdeen Glycinate, 2x1000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 12.35u shower 12.50u Eat 2 slices of bread and a cup of green tea 13.00u lying on the couch, big fatique, mood neutral. 16.45u take 1mg lorazepam, 5,8 mg Paroxetine, 2 x 500mg gaba, 2x5mg Lithium Orotate and 2x 500mg L-Tyrosine, 1x400mg magnesium citrate , 1x1000mg vit. C, 2x1mg Molybdeen Glycinate, and 2x1000mg Omgea 3-6-9 17.00u Dinner and watching TV, a liilte less tired and neutral mood, not much anxity, just not myself yet. 17.45u take a smoke and coffee, flurries of "normality", mixed with a little panic, fear for fear (don't know the englisch word for it), but mind seemed noot to go on rampage this time, breathing OCD seems quiet, alltough I feel CNS is very unstable, from tiredness to little panic in minutes. 18.30u another smoke and coffee and some pc stuff, mood not bad, less disconnencted from surroundings then yesterday. (smoking is a big stressor for me, but to addicted to stop now, but smoke mostly after dinner and keep it low.) I seem more sensitive then an atomwatch, continued scanning how my moods is. Feel flurries of normality (whats the word?) again. Tiredness further subseeding. to be continued 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
PerAsperaAdAstra Posted March 24, 2021 Share Posted March 24, 2021 Hi @Fallensoul! I'm also tapering off of Seroxat so I'm following. You're using quite a hefty combination of medications: Mirtazipine, Seroxat, Clomipramine and Lorazepam. I'm just a layman but I'm not surprised that you're not feeling super at this moment, nor that you're tired. Why are you using GABA supplements by the way? I'd really abstain from using GABA agonists whilst on benzos if I were you. 2 Antidepressant history 2001 - 2018: Paxil / seroxat (20 mgs), several failed c/t and taper attempts. 2018-September: last failed c/t attempt. 2018-October: reinstated Paxil (30 mgs) 2018-October thru 2019-January: Short-term Oxazepam & Diazepam use. Tapered off very slowly. Jumped 10Jan2019. Brassmonkey Slide Method stats Currently on hold on 0,1 mgpw after an updose due to becoming increasingly unstable. Supplements: C, D, Magnesium Miscellaneous: low on alcohol (1/2 times/year). No substance abuse. Lower carb diet with cheat days. Wim Hof Method. Buteyko. Calisthenics. Hiking. Link to comment
Fallensoul Posted March 25, 2021 Author Share Posted March 25, 2021 Don't know why I can't edit my post, but here follows the rest: of 24-3-2021 19.30u Walking with the dog, more energy, mood neutral 20.15u take orange juice and a smoke, and do some pc stuff, and drive a bit woth my car. Diirectly a little anxiety is arround the corner. 22.00u take 0,5mg lorazepam and 0,5 mg Lormetazepam and 2,7 mg Mirtazipine, 2 x 500mg gaba, 2x5mg Lithium Orotate and 2x 500mg L-Tyrosine, 1x400mg magnesium citrate , 1x1000mg vit. C and 2x1mg Molybdeen Glycinate, 22.30u, walking with the dog, fatique is gone 22.50u, again like every time, mood lifts, this time even more, I feel allmost normal, take a smoke or two and do some pc-stuff, surfing the web, tweak some Skyrim enb. 1.00u take 27mg Clomipramine and go to bed. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Fallensoul Posted March 25, 2021 Author Share Posted March 25, 2021 19 hours ago, PerAsperaAdAstra said: Hi @Fallensoul! I'm also tapering off of Seroxat so I'm following. You're using quite a hefty combination of medications: Mirtazipine, Seroxat, Clomipramine and Lorazepam. I'm just a layman but I'm not surprised that you're not feeling super at this moment, nor that you're tired. Why are you using GABA supplements by the way? I'd really abstain from using GABA agonists whilst on benzos if I were you. Hey PerAsperaAdAstra, Yes it's a mess, luckely not on high doses anymore, but I want to get ride of this evil stuff asap. The fatique has realy started a few weeks ago, before is was restless, panicly and ver anxious for nothing. I really dont understand where the extreme fatique is coming from, also mentally. Later on the day it subseeds, and late evening esp when 2,7 Mirt taken I'm allmost normal, but the next day the story repeats itself. Today even worse fatique, not a dowm mood atm. The supplements are on advise of my orthomoleculair doctor. He said my CSN is overstimulated and wants me even try 5htp and st John wort but I hesitate because I'am on so many serotoninic drugs allready. How are you holding up? 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Emeritus Erell Posted March 25, 2021 Moderator Emeritus Share Posted March 25, 2021 3 hours ago, Fallensoul said: The supplements are on advise of my orthomoleculair doctor. He said my CSN is overstimulated and wants me even try 5htp and st John wort but I hesitate because I'am on so many serotoninic drugs allready I would be very cautious : supplements that might help can be risky for people with a destabilised and sensitive CNS. Please take a read at these threads : 1. 5-htp-5-hydroxytryptophan-and-l-tryptophan/ 2. st-johns-wort-hypericum-perforatum/ 3. important-topics-about-tests-supplements-treatments-diet/ Take care ☀️ 1 2006 : 20mg Paxil+Bromazepam. 2008 : cold turkey of both. 2010 : Reinstatement 20mg Paxil + Bromazepam. 2014-June2017 : Switch from Bromazepam to Prazepam, slow taper to 0mg. 2018 to August 2019 : Paxil 20mg taper (3% every 15 days). 22 Aug 2019 updose to 10mg (was at 8.4mg). 25th Sept 2019 To April 2020 : found SA, holding at 10mg Paxil. April 2020 : Paxil 10mg to Prozac 7mg bridge. Details : topic/21457 Current Supplements : magnesium citrate + fish oil Current medication : * 7pm Diazepam : 0.85mg (15 Aug 2022) / 0.95 mg (24 April 2022) / 1mg Diazepam (since 29 Aug 2020) * 8am Prozac : 6.16mg (25 oct 2022, feel awful, slight updose) / 6.08 mg (9 oct 2022) / 6.24mg (11 July 22) / 6.44mg (22 May 22) / 6.64mg (4 Nov 21) / 6.72mg (8 oct 21) / 6.8 mg (15 Sept 21)/ 6.88mg (14 Aug 21)/ 6.92mg (23 Jun 21) I am not a professional, I don't give medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. Link to comment
Administrator Altostrata Posted March 25, 2021 Administrator Share Posted March 25, 2021 Please post at least 24 hours of notes at a time. We have to see the entire 24-hour cycle. On 3/19/2021 at 9:22 AM, Fallensoul said: I wonder where the extreme fatique is coming from. First I had 2 years off anxiety, panic, restnessless etc (also during Clomipramine build period to 50mg). and now I sleep 10-12 hours a day, move myself to the couch and lie down till 15u, before there is any life in this brain and body and can manage daily impulses. You're taking lorazepam all day long and you wonder why you're so tired? Oh, and how could we overlook a touch of lormetazepam? Please add that to your signature. 23 hours ago, PerAsperaAdAstra said: You're using quite a hefty combination of medications: Mirtazipine, Seroxat, Clomipramine and Lorazepam. I'm just a layman but I'm not surprised that you're not feeling super at this moment, nor that you're tired. Quite right. You're taking at least 3 "brakes", lorazepam, mirtazepine, and clomipramine plus, arguably, paroxetine. It seems likely to me you feel a little better in the evening because that's when the nightly mirtazepine and clomipramine start wearing off, before you take your next nightly dose of the 2 long-acting drugs. "Depression" can be an adverse effect from long-time benzodiazepine use. Being your main complaint is fatigue, it's perplexing that you've added some brake-like supplements to the soup. What are they supposed to accomplish? My guess is that the combination of lorazepam, lormetazepam, mirtazepine, clomipramine, and paroxetine is making you dopey, especially the benzos. You have overdone the brakes. If I were you, I'd gradually back out of all those supplements and start tapering the benzos. @Frogie will help. This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Fallensoul Posted March 25, 2021 Author Share Posted March 25, 2021 1 hour ago, Altostrata said: Please post at least 24 hours of notes at a time. We have to see the entire 24-hour cycle. You're taking lorazepam all day long and you wonder why you're so tired? Oh, and how could we overlook a touch of lormetazepam? Please add that to your signature. Quite right. You're taking at least 3 "brakes", lorazepam, mirtazepine, and clomipramine plus, arguably, paroxetine. It seems likely to me you feel a little better in the evening because that's when the nightly mirtazepine and clomipramine start wearing off, before you take your next nightly dose of the 2 long-acting drugs. "Depression" can be an adverse effect from long-time benzodiazepine use. Being your main complaint is fatigue, it's perplexing that you've added some brake-like supplements to the soup. What are they supposed to accomplish? My guess is that the combination of lorazepam, lormetazepam, mirtazepine, clomipramine, and paroxetine is making you dopey, especially the benzos. You have overdone the brakes. If I were you, I'd gradually back out of all those supplements and start tapering the benzos. @Frogie will help. The last page is a followup from the former field as I couldn't edit the post anymore, so 3 days are now posted? Yes I take 3,5mg Lorazepam and 0,5mg Lormetazepam and shared that half under Lorazepam, I will correct it. Not to be the wise guy, but I never had any problems with fatique before, doing the same regime (without the supplements), just the last few weeks. Before it was anxiety, restnessless and panic, but that could also be due the buildingup phase (and high dosage) of Clomipramine and more pronounced Paroxetine withdrawal? And maybe the supplements gave it the last edge? Anyway, I will taper the supplements down starting now, along with the benzo's (5-10%/month?), alltough I read here, doing AD's first and then benzo's? I also taper the Paroxetine with 5-10% a month. Should I hold the Clomipramine for a while (I wanted it also bring down to 20 or 25mg) , wouldn't it be to much all together? @Erell, thanks, I allready read some parts and are hesitant for making more chaos indeed. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Administrator Altostrata Posted March 25, 2021 Administrator Share Posted March 25, 2021 If I were you, I'd stop tapering everything else and taper the benzos. As for why you're getting these symptoms now, you added clomipramine last November, plus all those supplements in January. All of these drugs interact. Reduction of clomipramine did not seem to resolve the issue. By the way, did you speak to your doctors about these undesirable effects? This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner. "It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein All postings © copyrighted. Link to comment
Fallensoul Posted March 25, 2021 Author Share Posted March 25, 2021 34 minutes ago, Altostrata said: If I were you, I'd stop tapering everything else and taper the benzos. As for why you're getting these symptoms now, you added clomipramine last November, plus all those supplements in January. All of these drugs interact. Reduction of clomipramine did not seem to resolve the issue. By the way, did you speak to your doctors about these undesirable effects? I take that in considering, but I really want get rid a the paroxetine too, because that made me so sick when it stopped working. I have a terrible doctor and to get another one takes 5 months here after the cuts in care . He wanted me to stop paroxetine allmost CT when on 6mg and go to 100mg Clomipramine. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
Moderator Frogie Posted March 25, 2021 Moderator Share Posted March 25, 2021 Hi! From your signature you are taking 3.5 mg of lorazepam a day, is that correct? It will make you very tired. If I were you I would stop all other tapers and start tapering the benzo as @Altostratasaid above. If you would like help, please let me know. Take care, Frogie xx 1 PREVIOUS medications and discontinuations: Have been on medications since 1996. Valium, Gabapentin, Lamictal, Prilosec and Zantac from 2000 to 2015 with a fast taper by a psychiatrist. Liquid Lexapro Nov, 2016 to 31-March, 2019 Lexapro free!!! (total Lexapro taper was 4 years-started with pill form) ---CURRENT MEDICATIONS:Supplements:Milk Thistle, Metamucil, Magnesium Citrate, Vitamin D3, Levothyroxine 25mcg, Vitamin C, Krill oil. Xanax 1mg 3x day June, 2000 to 19-September, 2020 Went from .150 grams (average weight of 1 Xanax) 3x day to .003 grams 3x day. April 1, 2021 went back on 1mg a day. Started tapering May 19, 2023. July 28, 2023-approximately .87mg. Dr. fast tapered me at the end and realized he messed up. Prescribe it again and I am doing "slower than a turtle" taper. 19-September, 2020 Xanax free!!! (total Xanax taper was 15-1/2 months-1-June, 2019-19-September, 2020) I am not a medical professional. The suggestions I make are based on personal experience. Link to comment
Fallensoul Posted March 26, 2021 Author Share Posted March 26, 2021 Hi Frogie, yes 3,5 and 0,5mg Lormetazepam for the night. Maybe I'm stubborn, but I really want finish the Paroxetine and Clomipramine taper first, because the way they let me feel (in higher dose) was so terrible, that was way beyond anxiety and fatique. I rather am tired then go through that hell again. They don't feel right. The plan I had was to taper the Paroxetine down with 5-10%/month completely and the Clomipramine down to at least 20-25mg, and then start with the benzo's with 5-10%/month. The AD's also make me to have OCD, and now I'm much lower in dose, it is much, much better, despite the heavy fatique. Offcours benzo's taper isn't a small task either, I know. I'm now in dilemma what to do, I really want to finish the paroxetine. 1998-2020 Paroxetine 20mg, stopped working 2018/08 tapered down to 6mg now @ 1%/week 2019 /04 Lorazepam 3x1mg, 1x0,5mg night, Lormetazepam 0,5mg night2019/05 Buspirone addition 3x5mg worked like wonders for one month, stopped ct 2019/12 Mirtazipine, first 2x10mg til 2021/2, no effect, now 3mg for sleep2020/06 Wellbutrin 6 weeks, no effect stopped ct 2020/08 Lexapro, trying, to crossover, got crazy from 1 mg/day after 6 days, stopped2020/11 Clomipramine to 50mg, adverse effect, restless, panic, low mood, anxiety, fast taper down to 30 (plan is go to ~20 and hold and taper only parox. and benzo's and maybe Mirt if I sleep) 2021/1 3x1000mg gaba, 3x10mg Lithium Orotate, 3x 1000mg L-Tyrosine,2-3 times 1x400mg magnesium citrate , 2-3 times 1x1000mg vit. C,1x15mg Zinc, 3 times 2mg Molybdeen Glycinate, 2 times 2000mg Omgea 3-6-9 and 1x16mg B6 (P5P) 2021/03/17 Gaba, Tyrosine and Lithium orotate to 3x1 tablet. 2021/03/17 Cl 30, P 5,8. 2021/03/20 Cl 28. 2021/03/23 M 2,7. 2021/03/25 M 2,6, Cl 26, P 5,7. 2021/03/28 Cl 25. 2021/04/1 P 5,6. 2021/04/07 Cl 24,P 5,5. 2021/04/08 Cl 23,5. 2021/04/13 P5,4 2021/03/26 Lor 3x0,9, 1x0,45 night, Lorm 0,45night 2021/04/13 CL 23, M 2,5. 2021/04/16 Cl 22,5, P 5,3. 2021/04/18 M 2,4. 2021/04/24 Cl 22. 2021/04/29 M2,3, P5,28. 2021/05/8 Cl 21,5. 2021/05/9 M 2,2, P 5,22. 2021/05/12 Cl back to 22, 2021/05/20 Lor 3x0,8, night 1x0,40 Lorm 1x0,40 2021/05/27 Cl 20(holding)2021/05/28 P5,15 (holding)2021/05/31 Cl 22 (holding) 2021/06/7 Lor 3x0,75 1x0,38 night, Lorm 0,38night 2021/11/7 P5 Link to comment
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