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Ivengeline: Trouble with Zofran, Possible Adverse Reaction


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Hi Robibi! I have the exact same story like you!! 

I had burn out, then took 1 Zofran pill and now my brain is switcht on 24/7. I have these symptoms like you;


-brain always on

-never get tired

-lack of drifting sensation

-lack of fatigue in general

-feeling as if on 10 cups of coffee

-wide awake but completely exhausted


How are you doing now? Are you sleeping? I’m really worried I will never get better :( my health is going worse because of this. Can’t live like this anymore. I really want to be in contact with you. You are the only one with the exact same symptoms 


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  • Moderator

Hello, and welcome to SA.  We are a peer owned and run forum of people who have been or are getting off of psychiatric drugs.  I have moved your post to your own thread in the Introduction and Updates forum, so we can help you.  This is your own thread to ask questions, make comments, and receive support and help.  It sounds like you may have had an adverse reaction to Zofran, but I don't know for sure.  Knowing your drug history will help us help you. 


Can you please give us specific information about your drug history?  Please read the link below for instructions.  This will allow us to give you the best guidance.  


How to List Drug History in Signature


Once we know more about what drugs you took and your history with them, we can help you.  We look forward to hearing from you again.   




Edited by getofflex

Please do not private message me or tag me.


***Please note this is not medical advice.  Discuss any decisions about your medical care with a doctor who understands psych meds and how to withdraw from them, if you can find one.


Lexapro   Started Apr 15 2010 - 10 mg;  started taper August 2017, recent taper info: Apr 2 '20  0.18 mg; Jul 16  0.17 mg, Aug 23  0.16 mg, Oct 7  0.15 mg, Nov 8 - 0.14, Jan 16 '21 - 0.13, Feb 7 - 0.12, Feb 22 - 0.11, Mar 26 - 0.10, May 21 - 0.09, June 15 - 0.08 Aug 16 - 0.07, Oct 6 - 0.06, Nov 21 0.05, Dec. 17 0.04, Jan 14 '22 0.03, Feb 19 0.02, Apr 18 0.01, May 15 0.005,  Jul 8, 0.00.  Psych Drug Free as of July 8, 2022!!  Woohoo!!!

other meds: Levothyroxine 75 mg

magnesium in small amounts at 4 AM, 3 PM, before bed

suppl AM: fish oil, flax oil, vit C, vit E, multivitamin, zinc

suppl 8 PM: magnesium 350 mg, Estroven, melatonin 2 mg


Paxil 2002 - 2010, switched to Lexapro 2010 

Trazodone 50 mg. 2002 - 2019, fast tapered in 2019 

Xanax 0.5 mg as needed 2002 - 2019, up to 3x weekly 

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