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Any advise please - venlafexine


FarmMom

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Hello all, 

I have suffered for now 3 months to day, I have no appetite, hard to eat, down 26 pounds in 3 months, and terrible insomnia.  I am seeing my doctor today and I am desperate. 

I don't know what she will recommend, all blood work is normal. I never had any problems tapering until January after receiving the COVID vaccine (Pfizer). Not sure if the stress of the vaccine threw me in withdrawal, but the suffering isn't improving. I wish I had never gotten it, but I can't change that. Looking for recommendations for my PCP. Should I attempt the smallest dose of prozac, increase my venlafexine dose, or ask for soemthing to help me sleep. I really need my appetite to return. I am so weak and I must be able to work. 

Effexor 75mg 2007

2014 dropped to 37.5mg per MD. Back to 75mg in 4 days. 

February 2020 began slow taper 7-10% monthly 75mg-12.20.20 23.75mg

1.7.21 22.45mg, 1.28 21.1 mg, Received COVID vaccine Pfizer- had increase heart rate which led to panic attack, nausea, lost appetite.

5 days of severe panic/anxiety after 

1.31.21 increased 22.9mg, 2.25.21 increased 23.25mg, 3.14.21 22.5mg

3.23.21 22.125mg, Had a sudden loss of family member. Loss of appetite, anxiety, nausea 

3.25.21 Increased 22.5mg, 4.8.21 increased 23.625 mg, 4.19.21 increase 24.75 mg

5.1.21 Increased 31mg (had a few good days and felt hungry) 5.15.21 Increased 37.5mg (emotional numbness set in) June 5.21 Increased 43.75mg June 15.21 Increased 50mg 

Since 2007 I have also had alprazolam 0.25mg prescribed, but use infrequently.

 

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  • 2 years later...
  • Mentor

@FarmMom, how are you doing now?

Disclaimer:  This is not professional medical advice but is based on personal experience only.

1994 - 2017:  Prozac, Cymbalta, Celexa, Paxil, Wellbutrin, Zoloft, Seroquel, Buspar, Lorazepam, Xanax, Ambien

2005-present:  Trazodone 50 mg 

2017:  Effexor XR 37.5 >> 75 mg 

2020 (March):  Began 10% monthly taper of Effexor XR (got down to 12 mg)

2021 (September):  Completely crashed.  Went back up to 37.5 mg but in doing so I kindled myself

2024:  1/1:  35.6 mg (-6 beads)  |  2/1:  33.8 mg (-11 beads)  |  3/1:  32.1 mg (-16 beads)  |   4/1:  (-18 beads)

Reasons for starting psych meds:  PMDD/Depression, Generalized Anxiety Disorder

Other medications:  Levothyroxine 75 mcg

Supplements:  Dr. Berg's Electrolyte Powder on occasion   

 

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Hi @Catina7

I slowly increased back up and am at 68mg right now but am glad to say I am doing well and enjoying life. It was so terrible what I went through that I'm not sure I will attempt to taper again 😭

I am very grateful for where I am today! 

 

How are you? 

Effexor 75mg 2007

2014 dropped to 37.5mg per MD. Back to 75mg in 4 days. 

February 2020 began slow taper 7-10% monthly 75mg-12.20.20 23.75mg

1.7.21 22.45mg, 1.28 21.1 mg, Received COVID vaccine Pfizer- had increase heart rate which led to panic attack, nausea, lost appetite.

5 days of severe panic/anxiety after 

1.31.21 increased 22.9mg, 2.25.21 increased 23.25mg, 3.14.21 22.5mg

3.23.21 22.125mg, Had a sudden loss of family member. Loss of appetite, anxiety, nausea 

3.25.21 Increased 22.5mg, 4.8.21 increased 23.625 mg, 4.19.21 increase 24.75 mg

5.1.21 Increased 31mg (had a few good days and felt hungry) 5.15.21 Increased 37.5mg (emotional numbness set in) June 5.21 Increased 43.75mg June 15.21 Increased 50mg 

Since 2007 I have also had alprazolam 0.25mg prescribed, but use infrequently.

 

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  • Mentor
Just now, FarmMom said:

Hi @Catina7

I slowly increased back up and am at 68mg right now but am glad to say I am doing well and enjoying life. It was so terrible what I went through that I'm not sure I will attempt to taper again 😭

I am very grateful for where I am today! 

 

How are you? 

 

I'm glad you're doing better 😊.  I went through a similar nightmare with the Effexor.  I'm currently at 37. mg and am scared to taper any further, although I desperately want to be off of it.  

Disclaimer:  This is not professional medical advice but is based on personal experience only.

1994 - 2017:  Prozac, Cymbalta, Celexa, Paxil, Wellbutrin, Zoloft, Seroquel, Buspar, Lorazepam, Xanax, Ambien

2005-present:  Trazodone 50 mg 

2017:  Effexor XR 37.5 >> 75 mg 

2020 (March):  Began 10% monthly taper of Effexor XR (got down to 12 mg)

2021 (September):  Completely crashed.  Went back up to 37.5 mg but in doing so I kindled myself

2024:  1/1:  35.6 mg (-6 beads)  |  2/1:  33.8 mg (-11 beads)  |  3/1:  32.1 mg (-16 beads)  |   4/1:  (-18 beads)

Reasons for starting psych meds:  PMDD/Depression, Generalized Anxiety Disorder

Other medications:  Levothyroxine 75 mcg

Supplements:  Dr. Berg's Electrolyte Powder on occasion   

 

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I wish I had stopped going up but was desperate. I often think of getting back to 75 since I'm so close and I don't have to count anymore. 

Glad to hear you're doing better also. The crashing most definitely causes a traumatic response. 

I never had an issue tapering until I did. 

Effexor 75mg 2007

2014 dropped to 37.5mg per MD. Back to 75mg in 4 days. 

February 2020 began slow taper 7-10% monthly 75mg-12.20.20 23.75mg

1.7.21 22.45mg, 1.28 21.1 mg, Received COVID vaccine Pfizer- had increase heart rate which led to panic attack, nausea, lost appetite.

5 days of severe panic/anxiety after 

1.31.21 increased 22.9mg, 2.25.21 increased 23.25mg, 3.14.21 22.5mg

3.23.21 22.125mg, Had a sudden loss of family member. Loss of appetite, anxiety, nausea 

3.25.21 Increased 22.5mg, 4.8.21 increased 23.625 mg, 4.19.21 increase 24.75 mg

5.1.21 Increased 31mg (had a few good days and felt hungry) 5.15.21 Increased 37.5mg (emotional numbness set in) June 5.21 Increased 43.75mg June 15.21 Increased 50mg 

Since 2007 I have also had alprazolam 0.25mg prescribed, but use infrequently.

 

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