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How much water to mix drops with?


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I've been taking Cipralex drops for the last couple of years, and slowly tapering off.

 

I'm currently on 3 drops, down from 10. It occurred to me that I'm putting the drops in a glass full of water like I did when I was on the full dose. Does this make any difference in the absorption of drug, should I use less water?

 

On the same note, if the water doesn't make much difference, will I get the same result by putting the 3 drops on a teaspoon and putting that in my mouth?

Oct 2018 - Jun 2020: 10 mg per day generic Escitalopram in pill form.

Jul 2020 - Aug 2020: Switched to 9 mg per day of Cipralex drops to aid tapering.

Sep 2020 - Oct 2020: Taper to 8 mg.

Nov 2020 - Dec 2020: Taper to 7 mg.

Jan 2021 - Feb 2021: Taper to 6 mg.

Mar 2021 - Apr 2021: Taper to 5 mg.

May 2021 - Jun 2021: Taper to 4 mg.

Jul 2021 - Present: Taper to 3 mg.

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Hi Jon, 

welcome to SA. You are doing a good job tapering slowly but at the low dosages that you are at, you may want to consider going slower. The following two threads explain why that is important. 

 

Why taper by 10% of my dosage? - Tapering - Surviving Antidepressants

Why taper? SERT transporter occupancy studies show importance of gradual change in plasma concentration - Tapering - Surviving Antidepressants

 

I would also suggest that you start using a syringe instead of a dropper - the droppers are not accurate and variation in dose from day to day can make your nervous system even more sensitized to further drops. You can get a 1ml syringe from the pharmacy and use that to measure the dose that you're currently on. 

 

There is no problem with dissolving the liquid in water - it gets dissolved in your stomach anyway. I would suggest that it is probably the better way to do it rather than put them on a spoon and lick them as some portion may remain on the spoon but if you can lick the spoon really well, I guess it is fine. 

 

It is really important at the low doses to be careful as a tiny change when you are in the low doses may mean a high percentage change in receptor occupancy (some research showing that - pls see above). 

 

Kudos on doing such a good job tapering. 
OMW

If you would like to get a response from me directly please type @Onmyway some place in your message so I get notified of your post. I am not able to follow all of the threads all the time.

 

Aug  2000 - July 2003 (ct, 4-6 wk wd) , citalopram 20 mg,  xanax prn, wellbutrin for a few months (don't remember dates), trazodone prn 

Dec 2004 - July 2018 citalopram 20 mg, xanax prn (rarely used)

Aug 2018 - citalopram 40 mg (self titrated up)

September 2018 - January 2019 tapered citalopram - 40/30/20/10/5 no issues until a week after reaching 0

Feb 2019 0.25 xanax/day, then 0.5/day (3 weeks) over to klonopin 0.25 once a day to manage severe wd

March 6, reinstated citalopram 2.5 mg (liquid), klonopin 0.25 mg for sleep 2-3 times a week

Apr 1st citalopram 2.0 mg (liquid), klonopin 0.25 once a week, 

citalopram (liquid) 4/14/19 -1.8 mg, 5/8/19 - 1.6 mg,  7/2719 -1.5 mg,  8/15/19 - 1.35, 2/21/21 - 1.1 (smaller drops in between), 6/20/21 - 1.03 mg, 8/7/21- 1.025, 8/11/21 - 1.02, 8/15/21 - 1.015, 9/3/21 - 0.925 (fingers crossed!)

Supplements: magnesium citrate and bi-glycinate

 

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Thanks so much for the advice!

 

A quick question about the syringes. I’ve found a few on Amazon that get good reviews, but how do I get the liquid out of the Cipralex bottles easily?

 

They’re so tiny I’m not sure I could dip a syringe in to fill it. Or are they filled from the top or a different way?

Oct 2018 - Jun 2020: 10 mg per day generic Escitalopram in pill form.

Jul 2020 - Aug 2020: Switched to 9 mg per day of Cipralex drops to aid tapering.

Sep 2020 - Oct 2020: Taper to 8 mg.

Nov 2020 - Dec 2020: Taper to 7 mg.

Jan 2021 - Feb 2021: Taper to 6 mg.

Mar 2021 - Apr 2021: Taper to 5 mg.

May 2021 - Jun 2021: Taper to 4 mg.

Jul 2021 - Present: Taper to 3 mg.

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