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Lewis, 2021 Four research papers I wish my GP had read before prescribing antidepressants

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Lewis S. Four research papers I wish my GP had read before prescribing antidepressants. Br J Gen Pract. 2021 Jun 24;71(708):316-317. doi: 10.3399/bjgp21X716321. PMID: 34319885; PMCID: PMC8249025.

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1980s: First diagnosed with depression. Treated with a tricyclic. 1988: Switched to Prozac 20 mg.  1990s to 2010: On and off Prozac. Increased dose led to side effects. 2011: Put on Zyprexa. 2011: Work burnout and breakdown. Hospitalized for suicidal depression. Switched to Seroquel. Switched to Celexa 40 mg and lithium 300 mg. 2019: Stopped Seroquel. 

2020 July: Decreased Celexa to 30 mg in attempt to alleviate sexual dysfunction. Worked somewhat.

2020 August: Decreased Celexa to 20 mg. Sexual function improved but w/d effects started. 

2020 September: Maintaining Celexa at 20 mg. Experiencing w/d effects - fatigue, dysphoria, mood instability

2020 September 13: Increased Celexa to 30 mg due to w/d effects. Still on lithium 300 mg/day.

2020 October 3: Reduced Celexa to 27 mg. Started taper. 10% per month as recommended.

2020 October 18: Reduced to 24 mg.

2020 December 4: Reduced to 21 mg.

2020 December 23: Reduced to 20 mg (spacing out taper intervals due to persistent w/d effects)

2021 September 23: Several reductions over the past 9 months to 7.0 mg. Stressful life circumstances led me to feeling very depressed with suicidal feelings, so upped to the dose to 10 mg until I feel better. 

 

 

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  • Altostrata changed the title to Lewis, 2021 Four research papers I wish my GP had read before prescribing antidepressants
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Thanks. Please copy and paste the abstract from this article into this topic. If you wish, copy selections for discussion.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

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