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Starling: please help me understand my mirtazapine withdrawal


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I would greatly appreciate your wisdom and experience in helping me understand my mirtazapine withdrawal experience


My name is Terry and my general practitioner prescribed mirtazapine for insomnia, emotional burnout, anxiety, and depression. I was desperate at the time and did not know what I was getting into. Instead of taking time off work and focusing on myself, I decided to take the pill. I was on 7.5 mg from March to July 2021 and then decided to taper off it. I followed a tapering plan I had found here: http://www.citap.org.uk/SSRI-Tables.pdf


I decided to taper and stop the drug because the side effects started outweighing the benefits. 


I have been off mirtazapine since September (over three months now) and I would like to share my withdrawal symptoms with you. I am not sure if the protracted withdrawal is due to mirtazapine and the way I tapered or 1) if I am simply losing my mind or 2) I have a serious underlying health issue.


Generally speaking, I feel like someone has hacked into my mind and body and has programmed it to malfunction and go berserk.


At the moment, I am suffering from:


  • Insomnia (I might get one solid night's sleep a week, if I am lucky; otherwise, I have broken sleep or very little or no sleep at all.)
  • Lightheadedness 
  • Nausea
  • Heart palpitations (my heart races and feels like it is beating hard)
  • Nervousness
  • Anxiety
  • Hot flashes (in the middle of the night)
  • Depression (often feel like crying)
  • Numb and burning hands
  • Feeling unsteady on my feet
  • A general state of lethargy, weakness, and fatigue


I had blood work done and everything was normal. I also had a cerebral MRI and it was normal.


Are my symptoms part of mirtazapine protracted withdrawal? Is this "normal" in terms of withdrawal or should I be worried that it is due to something else?


I would greatly appreciate any reassurance and sharing of experience. I feel like I have become a hypochondriac because I do not know what is abnormal and what is due to the poison my body is trying to adjust to not having anymore.


Thank you for your time and help.




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  • ChessieCat changed the title to TerryK: please help me understand my mirtazapine withdrawal
  • Moderator

Hi @Starling


Welcome to SA. I'm sorry you are going through this but glad you found the site. We are all volunteer and have been through what you are going through, or we are going through it right along with you.


This is your page to receive information, ask questions, make comments and meet members like you. We ask that each member only have one page so we can keep all your information easily accessible.


First can you please create a signature.


Account Settings – Create or Edit a signature


I think in your case you are going through withdrawal. You could always reinstate a small amount and stabilize then taper off slowly to hopefully avoid more symptoms. I am going to give you a bunch of information for you to read and then you can ask all the questions you may need.


One Theory of Antidepressant Withdrawal Syndrome


Brain Remodelling


Digestive problems:  Nausea, Diarrhoea, Bloating, GERD


Emotional Numbness see Anhedonia


Fear, terror, panic, and anxiety


Reinstatement Suggestions


Here is some information on Melatonin.  It helps a lot of members on here with insomnia when taken in small amounts.




We don't suggest alot of supplements on here. But we do suggest magnesium and omega. If you want to try them take them one at a time and wait a few days to see how you react.




Omega-3 Fish Oil


I think I've bombarded you with some information for now. At this point, I think a very small reinstatement might help you. 


Read the information that I gave you on reinstatement and let us know if we can help you in anyway.


Please let us know if you have any questions we may be able to answer for you. You can always tag someone by using the @ sign then type the name. A list will come up and just select the members name on the list and then we will get your message faster.


Take care,

Frogie xx

Edited by Karma
Name update

PREVIOUS medications and discontinuations: Have been on medications since 1996. 

 Valium, Gabapentin, Lamictal, Prilosec and Zantac from 2000 to 2015 with a fast taper by a psychiatrist.

 Liquid Lexapro Nov, 2016 to 31-March, 2019 Lexapro free!!! (total Lexapro taper was 4 years-started with pill form)

---CURRENT MEDICATIONS:Supplements:Milk Thistle, Metamucil, Magnesium Citrate, Vitamin D3, Levothyroxine 25mcg, Vitamin C, Krill oil.

Xanax 1mg 3x day June, 2000 to 19-September, 2020 Went from .150 grams (average weight of 1 Xanax) 3x day to .003 grams 3x day.

19-September, 2020 Xanax free!!! (total Xanax taper was 15-1/2 months-1-June, 2019-19-September, 2020)

I am not a medical professional.

The suggestions I make are based on personal experience.

Link to comment
  • ChessieCat changed the title to TerryK: please help me understand my mirtazapine withdrawal
  • Karma changed the title to Starling: please help me understand my mirtazapine withdrawal

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