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gatos: mirtazapine withdrawals


gatos

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15 hours ago, gatos said:

Hi @Knosretep . Thank for noticing and caring enough to ask.
Yes, I have found another job. I managed to delay starting it as much as possible. I start on 1st of May. It will be a remote only thing, so I will be working from home. 
 

 

 That's great, congrats!  It's good you're able to work from home since you might be experiencing some bumps as you go through tapering.  Hopefully you'll be completely stable by your start date. 🙂

 

2013 - Jan 4, 2021 - Sertraline 50mg 

Jan 2021 - Venlafaxine 75mg (1/4)

Feb 2021 Mar 2021 - Venlafaxine 75mg

April 2021 - Venlafaxine 75mg, Amitriptyline 2mg (4/20), Clonazepam 2mg

May 2021 - Venlafaxine 75mg (5/16 - 0mg), Amitriptyline (5/1 - 1mg, 5/16 - 0mg), Clonazepam 2mg

Aug 2021 - Sertraline 25mg (re 8/20), Clonazepam 2mg 

Sep 2021 - Sertraline 50mg (up 9/3), Clonazepam (9/29 - 1mg), Diazepam (9/29 - 2.5mg)

Oct 2021 - Sertraline 50mg, Clonazepam (10/14 - 0.9mg, 10/24 - 1mg), Diazepam (10/6 - 1.25mg, 10/14 - 0mg), Trazodone (10/03 - 50mg, 10/17 - 25mg, 10/21 - 12.5mg), Mirtazapine (10/17 - 15mg)

Nov 2021 : Current - Sertraline 50mg, Clonazepam (4/22 - 0.975mg, 5/22 - 0.9125mg, co 6/22 - 0.25mg, co 8/22 - 0.5mg, co 1/23 - 0.25mg),

Diazepam (co 6/22 - 12mg, 7/22 - 11mg, co 8/22 - 5mg, 9/22 - 4mg, 10/22 - 3mg, 11/22 - 2mg, 12/22 - 1mg, co 1/23 - 5mg, 2/23 - 4.5mg, 3/23 - 3.5mg, 4/23 - 3mg), Trazodone 12.5mg, Mirtazapine 15mg

 

Supplements: 1/2 Multivitamin, Fish Oil 2000mgProbioticMagnesium Chelate 280mg, Vit C 500mg. Melatonin 5mg/3mgXR

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  • 3 weeks later...

Hi guys.

 

My progress so far. I have been consistent on ~13.2mg (137mg of a 310 mg pill) for over a month now. There are days that i sleep adequately and feell rested and relieved. But then there are days that the insomnia hits and then  **** hits the fan.

 

I have observed that the insomnia is caused mainly from bad thoughts during the day (rumination i guess) of what i have done to myself and how am i going to become normal again. I am afraid that i am deteriorating my health. These thoughs come at night and wake me up.

 

I have also observed that my sleep has greatly deteriorated since i started taking the pill consistently at 15mg (around at January Nd later reducing to 13.2) and of course it is when I found out about how bad that pill is. Before that i never had so bad sleep when not taking the pill for several days or even weeks. I was just waking up early (cortisol spikes?) In the morning.

 

Not sure what to do with that information. I guess my current dosage is either too little (should have started tapering at 30 maybe?) or too much (causes me over stimulating effect)?

 

I have booked appointments with an endocrinologist and a neurologist. I am thinking i might have mild serotonin syndrome (some of the symptoms are similar especially when the insomnia hits with elevated heart rate, perspiration and not being able to concentrate my thoughts on anything specific for more than a few seconds)

 

Any thoughts guys?

2016 - 2022: Gradually increasing dosages, non stable usage of Mirtazapin

15mg - 45mg (never exceeded), 5-6 times per week (had no idea this was bad for me)

Latest: Nov 2021 - Jan 2022: everyday 30mg - 45mg 

Currently:
14th of January - 17th of February: 15mg

18th of February - present: 13.5mg

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Hi @gatos

 

My thoughts:

 

It seems unlikely to be serotonin syndrome when you were taking 30-45mg everyday before (Nov2021 - Jan 2022) and didn't have this problem.  I guess the endocrinologist and neurologist can rule out it being serotonin syndrome, or confirm that's what is it.

 

My bet is that you're still not completely stable from the drop and the rumination is enough to tip you to insomnia, or like some days you are just down and that brings the rumination which coincides with insomnia.

 

Hope you find the answer and are able to recover your sleep!

2013 - Jan 4, 2021 - Sertraline 50mg 

Jan 2021 - Venlafaxine 75mg (1/4)

Feb 2021 Mar 2021 - Venlafaxine 75mg

April 2021 - Venlafaxine 75mg, Amitriptyline 2mg (4/20), Clonazepam 2mg

May 2021 - Venlafaxine 75mg (5/16 - 0mg), Amitriptyline (5/1 - 1mg, 5/16 - 0mg), Clonazepam 2mg

Aug 2021 - Sertraline 25mg (re 8/20), Clonazepam 2mg 

Sep 2021 - Sertraline 50mg (up 9/3), Clonazepam (9/29 - 1mg), Diazepam (9/29 - 2.5mg)

Oct 2021 - Sertraline 50mg, Clonazepam (10/14 - 0.9mg, 10/24 - 1mg), Diazepam (10/6 - 1.25mg, 10/14 - 0mg), Trazodone (10/03 - 50mg, 10/17 - 25mg, 10/21 - 12.5mg), Mirtazapine (10/17 - 15mg)

Nov 2021 : Current - Sertraline 50mg, Clonazepam (4/22 - 0.975mg, 5/22 - 0.9125mg, co 6/22 - 0.25mg, co 8/22 - 0.5mg, co 1/23 - 0.25mg),

Diazepam (co 6/22 - 12mg, 7/22 - 11mg, co 8/22 - 5mg, 9/22 - 4mg, 10/22 - 3mg, 11/22 - 2mg, 12/22 - 1mg, co 1/23 - 5mg, 2/23 - 4.5mg, 3/23 - 3.5mg, 4/23 - 3mg), Trazodone 12.5mg, Mirtazapine 15mg

 

Supplements: 1/2 Multivitamin, Fish Oil 2000mgProbioticMagnesium Chelate 280mg, Vit C 500mg. Melatonin 5mg/3mgXR

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@gatos

 

True serotonin syndrome is pretty dire but there are some of us who are very sensitive to it.

I researched mirtazipine through a friend and it does have serotogenic properties- so as you are probably now sensitive to it that may explain some symptoms. 
For me the only way was to get off it and sleep improvement started at 7.5 and below. 
 

Wishing you l well

OD 

My Intro topic.  Was Dickie in FB gabapentinoids 

2020 January Stopped Quetiapine 150 at night in a fairly chaotic fashion with holds, jumping at 6mg 

2020 June Stopped Pregabalin 150 at night using Ashton Method Some holds. 

2021 December Stopped Mirtazipine 15 using Ashton Method. (Slower at end). 

Nov 21 - Given Quetiapine 12.5 for sleep. Reduced mid March 2022 to 6mg - Off 30/5/22

Feb 2022 Ongoing Diazepam 17.5, Blip at Christmas when took 22.5mg for a few days, now 24 FEB Stable 17.5 as advised. Had long covid. Now going to 16.25 from 8/7/22. 7% drop 

Oxazepam 10mg.STOPPED 10th FEB 2022  “Rescue dose x 2 in 2 months. 

Buccastem 3mg less than 1 a month for nausea. 

Past meds since 1969 -Approx dates only available. Tranxene 15, Clomipramine 150 for about 25 years. 1993 Paroxetine 20 AD change. Diazepam 20mg swap from Tranxene.

Oxazepam 10mg Prn since 1990's  1995 Trial of MAOIS. 2000 Escitaopram 10mg. 2015 trial of Trazadone. 2004 Pregabalin 150 at night.

2015 Started on Quetiapine 150 note, Mirtazipine 15 note. Diazepam increased to 30mg split dosing. 

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Hi @Knosretep and @OldDodgy

Thank you so much guys for replying. I really need some encouragement. Only just today I let someone else (apart from my girlfriend) know about my problem. I just told my sister about my problem but very briefly, she doesn't know any of the details. She helped me look up doctors.
I don't dare telling my parents, they are old, won't understand and probably get worried and sad.
 

I really need some help to get through this and you guys are like an oasis in an endless dessert. My girlfriend is trying her best but it is starting to affect her as she feels that she cannot help me.

I feel so bad not replying to your threads, I just find it overwhelming when I read what other people are going through and it terrifies me. I will try to catch up with you guys.
 

38 minutes ago, Knosretep said:

My bet is that you're still not completely stable from the drop and the rumination is enough to tip you to insomnia, or like some days you are just down and that brings the rumination which coincides with insomnia.

As I read this it makes sense.
I was feeling very well the last three days, well and optimistic that I started thinking perhaps I can go a bit lower. Then after a few google searches for mirtazapine withdrawals brought the bad thoughts back.

I looked up @OldDodgy's Ashton method and found this. I think the anxiety and insomnia paragraphs describe very well what I am dealing with.

2016 - 2022: Gradually increasing dosages, non stable usage of Mirtazapin

15mg - 45mg (never exceeded), 5-6 times per week (had no idea this was bad for me)

Latest: Nov 2021 - Jan 2022: everyday 30mg - 45mg 

Currently:
14th of January - 17th of February: 15mg

18th of February - present: 13.5mg

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44 minutes ago, gatos said:

Hi @Knosretep and @OldDodgy

Thank you so much guys for replying. I really need some encouragement. Only just today I let someone else (apart from my girlfriend) know about my problem. I just told my sister about my problem but very briefly, she doesn't know any of the details. She helped me look up doctors.
I don't dare telling my parents, they are old, won't understand and probably get worried and sad.
 

 

I can understand this.  It's tough to tell people, but it is really helpful to have support from people who know you and care about you.  Even if they end up not being as supportive as you'd like, at least they know there's a reason that you're maybe acting differently and will hopefully not hold that against you.

 

44 minutes ago, gatos said:

I really need some help to get through this and you guys are like an oasis in an endless dessert. My girlfriend is trying her best but it is starting to affect her as she feels that she cannot help me.

 

The hard truth is that no one can go through this for us, and no one can really make us better.  She can still help you by being supportive and understanding, but the healing is up to you.  Kinda like healing a broken bone, the most we can do is provide the body with adequate nutrition to heal, and prevent further injury to it while it heals.  It's the same for anyone supporting us.  As long as they are not causing us additional problems/stress and are doing anything to ease our symptoms or make our struggle more bearable then that's as much help as can be done.

 

44 minutes ago, gatos said:

I feel so bad not replying to your threads, I just find it overwhelming when I read what other people are going through and it terrifies me. I will try to catch up with you guys.
 

 

No worries.  It's overwhelming to think about what's going on with myself and terrifying too, so I try not to!  Can't blame you there!  😂

 

44 minutes ago, gatos said:

As I read this it makes sense.
I was feeling very well the last three days, well and optimistic that I started thinking perhaps I can go a bit lower. Then after a few google searches for mirtazapine withdrawals brought the bad thoughts back.

 

Hey, that's great news!  You felt well enough that you were thinking about cutting again! That's huge!  It hasn't been long at all (although it feels like ages) that you stepped down from 30-45mg and you're already having multi-day windows!  That's amazing really!

 

44 minutes ago, gatos said:

I looked up @OldDodgy's Ashton method and found this. I think the anxiety and insomnia paragraphs describe very well what I am dealing with.

 

I think you are gonna be just fine.  Give yourself some time to stabilise more and get back to that point you were at 3 days ago, but don't go reading up on Mirtazapine withdrawal this time.

2013 - Jan 4, 2021 - Sertraline 50mg 

Jan 2021 - Venlafaxine 75mg (1/4)

Feb 2021 Mar 2021 - Venlafaxine 75mg

April 2021 - Venlafaxine 75mg, Amitriptyline 2mg (4/20), Clonazepam 2mg

May 2021 - Venlafaxine 75mg (5/16 - 0mg), Amitriptyline (5/1 - 1mg, 5/16 - 0mg), Clonazepam 2mg

Aug 2021 - Sertraline 25mg (re 8/20), Clonazepam 2mg 

Sep 2021 - Sertraline 50mg (up 9/3), Clonazepam (9/29 - 1mg), Diazepam (9/29 - 2.5mg)

Oct 2021 - Sertraline 50mg, Clonazepam (10/14 - 0.9mg, 10/24 - 1mg), Diazepam (10/6 - 1.25mg, 10/14 - 0mg), Trazodone (10/03 - 50mg, 10/17 - 25mg, 10/21 - 12.5mg), Mirtazapine (10/17 - 15mg)

Nov 2021 : Current - Sertraline 50mg, Clonazepam (4/22 - 0.975mg, 5/22 - 0.9125mg, co 6/22 - 0.25mg, co 8/22 - 0.5mg, co 1/23 - 0.25mg),

Diazepam (co 6/22 - 12mg, 7/22 - 11mg, co 8/22 - 5mg, 9/22 - 4mg, 10/22 - 3mg, 11/22 - 2mg, 12/22 - 1mg, co 1/23 - 5mg, 2/23 - 4.5mg, 3/23 - 3.5mg, 4/23 - 3mg), Trazodone 12.5mg, Mirtazapine 15mg

 

Supplements: 1/2 Multivitamin, Fish Oil 2000mgProbioticMagnesium Chelate 280mg, Vit C 500mg. Melatonin 5mg/3mgXR

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@gatos

 

One thing I stopped doing is reading other horror stories.  You have your own story so focus on that.  When I thought I wouldn’t get over the anxiety and just the general feeling like garbage 24/7 I went to these two YouTube videos.  I did them both daily.  Maybe it can help you You.

 

 

 

I will also say as I keep decreasing my Mirtazapine I am having more good days than bad and definitely feeling more tired at night.  If I do too much it will catch up to me.  
 

you will get there, trust yourself.

June 9th 2021 Mirtazapine 7.5 mg

June 24th Mirtazapine 11.25 mg

Oct 25th tapered 16% and had major withdrawals on day 4.

Oct 29th went up original dose.

Dec 28th 2021 @ 11.25 

Dec 31st 2022 @ 5.5 

Dec 31st 2023 2.4

Jan 15th 2024 @ 2.2

Mar 5th 2024 @ 1.9

 

Supplement from standard process-  these are made with wholefoods-calm five, magnesium cream.

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