Valerio: Help withdraw clonazepam after quetiapine

[Valerio]

2 hours ago, Valerio said:

Hi Altostrata. How Are tou? I am taking only 0.5 mg of quetiapine because I have a recurrence of herpes zoster and I was hospitalized. As I threw up the quetiapine doses (6,25 mg) for about 5 days... I ended up changing the dose on May 15th.

Several factors such as intravenous antiviral schedules influenced this change.

 

I don't think I'm creating akathisia because this worsening started on Friday (July 1st). That same week I had herpes simplex. It could have been the herpes. Also, I had akathisia during taper from quetiapine last year and at times it comes back.

 

*How long should I wait before split pregabalin? 

* I made a mistake in the last post: my dose at 10:30 PM is 30 mg. My total dose of pregabalin is 50 mg.Wouldn't it be better to split it into three doses?

 

I won't trust any doctor anymore. I just want to get off these drugs safely. Tks for your help.

Another observation. I do not have relief after the 10:30 am dose. What happens is I start having akathisia 2 hours after taking pregabalin. This this offer with all doses.

[Valerio]

12 hours ago, Valerio said:

Another observation. I do not have relief after the 10:30 am dose. What happens is I start having akathisia 2 hours after taking pregabalin. This this offer with all doses.

UPDATE I've been thinking and looking at my notes and I believe I'm actually having a reaction to quetiapine. The sensation I have been having (akathisia) started with the withdrawal of quetiapine. Last year, I only felt this restlessness a few hours after taking quetiapine. But in the last week, I've been feeling after taking it. Perhaps it is a paradoxical reaction to quetiapine that is sensitizing my nervous system. With that, I ended up stopping tolerating pregabalin. What do you think?

 

8 a.m. Woke with akathisia
8 a.m. Akathisia 
9 a.m. Akathisia
10:30 a.m. 12,5 mg pregabalin
11:00 a.m. Akathisia stop
12:00 p.m. Akathisia stop

12:30 p.m. restless

1:00 p.m. lunch

2:00 - 5 p.m. feeling ok

5 p.m. 7.5mg pregabalin feeling ok
6 p.m. - 10 p. m. feeling ok

10:30 p.m. 30 mg pregabalin
11:30 p.m. restless
01:30 p.m. sleep
3:30 a.m. 0.5 quetiapina

4:00 a.m. restless, agitation, feeling alert

5:00 a.m. - 8 a.m. slep restes

9:00 a.m. akathisia

 

 

I know it was a bad choice to change the quetiapine dose. But I was in the hospital, vomiting a lot and desperate. Now, all I want is to stay stable and eliminate these meds. The doctors wanted to increase the pregabalin dose and add amitriptyline and I refused to do that. I am dealing with neuropathic pain day after day without taking any medication. There are days when the pain is very strong and I can stand it alone until it passes. Since hospitalization my withdrawal symptoms have gotten a lot worse. I'm going to have to stop work and I'm increasingly dependent on my husband. The antivirals, steroids and painkillers made me really sick. However, I know that you are my only healing path. Doctors have no idea what they're doing. Since leaving the hospital, I have committed myself to following the guidelines given by you here at the SA. I want to win all of this. Please don't give up on me.

 

 

 

 

 

 

 

 

 

[Altostrata]

Need to see more daily notes.

[Valerio]

On 7/6/2022 at 3:38 PM, Altostrata said:

Need to see more daily notes.

9 a.m. Akathisia
10:30 a.m. 12,5 mg pregabalin
11:00 a.m. Akathisia 
12:00 p.m. Akathisia 

12:30 p.m. restless or mild akathisia

1:00 p.m. lunch

2:00 - 5 p.m. feeling better

5 p.m. 7.5mg pregabalin, restless
6 p.m. - 10 p. m. feeling ok

10:30 p.m. 30 mg pregabalin
11:30 p.m. restless
01:30 - 3:30 p.m. sleep Ok

03:30 0.5 mg quetiapine

04:30 feeling awake and restless

05:00 - 08:00 AM sleep Ok

08:30 AM wake up with mild akathisia

 

 

 

 

 

 

 

 

[Carmie]

Hi @Valerio

 

Sorry that you’re struggling so much with Akathisia, I think it’s the worst symptom ever and my heart goes out to you. Please keep taking the daily notes for Alto. 
 

I’ve had severe Akathisia in the past too and if I taper too quickly I get it again, so I’m tapering extremely slowly and having long holds. I’m on 3.75 mg of quetiapine at the moment. 
 

When I had Akathisia it was there 24/7, I had no reprieve from it. So yours comes and goes throughout the day? 
 

Sending you hugs🤗

[Valerio]

1 hour ago, Carmie said:

Hi @Valerio

 

Sorry that you’re struggling so much with Akathisia, I think it’s the worst symptom ever and my heart goes out to you. Please keep taking the daily notes for Alto. 
 

I’ve had severe Akathisia in the past too and if I taper too quickly I get it again, so I’m tapering extremely slowly and having long holds. I’m on 3.75 mg of quetiapine at the moment. 
 

When I had Akathisia it was there 24/7, I had no reprieve from it. So yours comes and goes throughout the day? 
 

Sending you hugs🤗

Yes... it's a lot of suffering. Glad you were able to control the akathisia. It gives me hope.

When I stopped taking quetiapine the akathisia was 24/7. After I started taking pregabalin it got better. But last week I started to feel it again. I think it's because I've had a lot of herpes. As they are infections that disturb the nervous system, they must have sensitized even more. Good luck with your tapering. If I can help with anything, let me know. 🙏

[Valerio]

On 7/7/2022 at 4:13 PM, Valerio said:

9 a.m. Akathisia
10:30 a.m. 12,5 mg pregabalin
11:00 a.m. Akathisia 
12:00 p.m. Akathisia 

12:30 p.m. restless or mild akathisia

1:00 p.m. lunch

2:00 - 5 p.m. feeling better

5 p.m. 7.5mg pregabalin, restless
6 p.m. - 10 p. m. feeling ok

10:30 p.m. 30 mg pregabalin
11:30 p.m. restless
01:30 - 3:30 p.m. sleep Ok

03:30 0.5 mg quetiapine

04:30 feeling awake and restless

05:00 - 08:00 AM sleep Ok

08:30 AM wake up with mild akathisia

 

 

 

 

 

 

 

 

8:30 a.m. Woke with mild akathisia
8 a.m - 11 a.m. Akathisia

10:30 a.m. 12,5 mg pregabalin
11:30 a.m. Akathisia stop 
12:00 p.m. restless

1:00 p.m. lunch

2:00 p. m restless

3:00 - 6 p.m. feeling ok

5 p.m. 7.5mg pregabalin feeling ok
6 p.m. - 10 p. m. feeling ok

10:30 p.m. 30 mg pregabalin
11:00 p.m - 4 a. m. akathisia and total insomnia

3:30 a.m. 0.5 quetiapine

4:00 a.m. terrible akathisia (akathisia got worse)

5:00 a.m. - 11 a.m. akathisia

10:30 a.m. 12,5 mg pregabalin

11:30 a.m akathisia suddenly stopped 

 

 

[Altostrata]

Please stop using the term "akathisia" and describe the symptom instead.

 

It is possible you are having interdose withdrawal from quetiapine. It looks like the smaller pregabalin doses reduce this. 

 

When are you going to divide your pregabalin doses? I feel I have added all I can about this. The rest is up to you.

[Valerio]

4 hours ago, Altostrata said:

Please stop using the term "akathisia" and describe the symptom instead.

 

It is possible you are having interdose withdrawal from quetiapine. It looks like the smaller pregabalin doses reduce this. 

 

When are you going to divide your pregabalin doses? I feel I have added all I can about this. The rest is up to you.

11:30 a.m akathisia (urge to move my all body accompanied by periodic surges of adrenaline and cortisol (every 1 min) suddenly stopped

12:00 p.m - 3:00 p.m. restless

1:00 p.m. lunch

4:00 - 6 p.m. feeling ok

5 p.m. 7.5mg pregabalin feeling ok
6 p.m. - 10 p. m. feeling ok

10:30 p.m. 30 mg pregabalin
11:00 p.m - 01:00 a. m. Restless and urge to move mu body

01:00 - 02:00 p.m. restless sleep waking up with short of breath

3:30 a.m. 0.5 quetiapine

4:00 a.m. feeling awake and more restless

5:00 a.m. - 11 a.m. 

urge to move my body accompanied by periodic surges of adrenaline. Much crying, despair and catastrophic thinking. Aggressive with sensitivity to sound and light.

 

 

Ok Alto!

I'm going to divide (5 mg) tomorrow. what do you think? That way I don't put all the pregabalin in liquid at once.

 

I thought I had to wait more days since I had herpes recently . Thank you very much.

 

 

[Altostrata]

On 7/9/2022 at 5:59 PM, Valerio said:

11:30 a.m akathisia (urge to move my all body accompanied by periodic surges of adrenaline and cortisol (every 1 min) suddenly stopped

 

This was preceded by a pregabalin dose, was it not? How much pregabalin?

 

On 7/9/2022 at 5:59 PM, Valerio said:

I'm going to divide (5 mg) tomorrow. what do you think? That way I don't put all the pregabalin in liquid at once.

 

 

I don't know what you mean by this. 5mg of what?

 

You are taking 50mg pregabalin today. It appears that doses of 7.5mg and 12.5mg pregabalin are helpful, 30mg is too much and causes a paradoxical reaction.

 

Perhaps you can figure out how to divide and schedule your doses accordingly? I have to admit, I am tuckered out by this, maybe you can solve your own problem?

 

 

[Valerio]

6 hours ago, Altostrata said:

 

This was preceded by a pregabalin dose, was it not? How much pregabalin?

 

 

 

I don't know what you mean by this. 5mg of what?

 

You are taking 50mg pregabalin today. It appears that doses of 7.5mg and 12.5mg pregabalin are helpful, 30mg is too much and causes a paradoxical reaction.

 

Perhaps you can figure out how to divide and schedule your doses accordingly? I have to admit, I am tuckered out by this, maybe you can solve your own problem?

 

 

 

 

 

Yes, To answer the question..yes..in a few days akathasia precedes pregabalin and gets worse after taking it. But most days the akathisia starts after some medication (pregabalin or quetiapine).

 

 

 

10:30 a.m. 12,5 mg preganalin

5:00 p.m. 7,5 mg preganalin

9:30 p.m. 5 mg pregabalin (I will move 1 hour per day until 5 p.m.)

10:30 p.m. 25 mg pregabalin

3:30 a.m. 0.5 quetiapine

 

OK! I appreciate the help given so far. Just confirming... I should stop writing here. That's it? If that's the case, I don't ask for help anymore.

[Altostrata]

I have extensively explained why you may sometimes feel worse after taking a larger dose of pregabalin. I feel I've contributed all I can. Perhaps one of the other staff will assist you.

[Valerio]

😞 I hope someone can help me because I'm pretty lost.

[Guest]

Hi @Valerio how are u ? Are you better ?

[Valerio]

On 7/21/2022 at 3:37 PM, Quittingquentiapin said:

Hi @Valerio how are u ? Are you better ?

 

Hi, unfortunately i am still really bad with all of it. My health get really worse and i developed a recurrent herpes crises what make me sick and WD get worse..... 

 

I would like to ask some help with two things:

 

      1) I am taking quetiapine 0.5mg liquid, I making it by water tritation method where i add a 25mg quetiapine tablet and 25ml of water and wait a couple of hours to dissolve. But it seens not dissolve well and i am concern that this is causing dose variation and is not help me to get better.

 

      2) I used to measure the 0.5mg of quetiapine with a 1ml syringe where i drink 0.5ml of the liquid. An couples weeks ago i change the syringe to pipette thinking that it was more precise. But i realize that i was using micro pipette wrong and taking 0.6ml or 0.6mg of quetiapine instead of 0.5 mg. I have taken this for 2 or 3 weeks and i am really concern about it, because i got worse and realize this just yesterday. Now i don't know what to do, i keep taking 0.6mg? go back to 0.5mg? or something in the middle like 0.55mg?

 

please, could someone give me some advice what should i do?  i messed up my doses with change in syringe and now i am lost and worse.......

 

thank you

 

 

 

 

 

 

[Altostrata]

13 hours ago, Valerio said:

But i realize that i was using micro pipette wrong and taking 0.6ml or 0.6mg of quetiapine instead of 0.5 mg. I have taken this for 2 or 3 weeks and i am really concern about it, because i got worse and realize this just yesterday.

 

In what ways do you feel worse since you started measuring with a micropipette?

 

If you have been consistently taking 0.6mg while using the pipette, it is unlikely that is causing a big problem. 

 

What times o'clock do you take each of your drugs, with their dosages?

 

Please update your signature with events since May.

[Cheeky]

Hi @Valerio,

Im a fellow Seroquel user and really hate the drug . 
You’ve done really well getting to a smaller dose . Congrats

Im happy to share experiences with you and give you support though this . 
 

Cheeky