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How to make a liquid from tablets or capsules


Rhiannon

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Really? It seems like a lot of sediment to be all filler? I was thinking of getting Ora-Plus just to curb my ocd 

2008: start Lexapro 10 mg which is quickly upped to 20 mg. 2008:2013 try at least four individual times to get off Lexapro, never get lower than 5mg, settle at 15 mg. 2015: again, attempt to get off Lexapro and get to 5 mg. After 6 months, feel i'm stabilizing but go back on a higher dose because of one stressful event. 2016: go to 20 mg from 15 mg due to work stresses, hit severe tolerance for the first time and become very suicidal. 2016-2017: try viibryd and cymbata in an attempt to feel better. Also add Lamictal 150 at some point. 2017: eventually land on paxil 37.5 and Lamictal 150. January 2018: cut paxil to 25. April-July 2018: reduce Lamictal in 50 mg increments till im off August. 2018: reduce paxil to 20 mg. december 2018: dropped Paxil to 18 mg, SEVERE CRASH. March updosed to 20 mg April 11: dropped to 19.4 mg due to akathsia (still experiencing akathsia symptoms from updose) April 20: 19 mg Paxil May 4: 18.7 Paxil July 5: 18.2 July 12: 17.8 Aug 19: 17.5 Aug 26: 17.3 Oct 20: 17.1 Nov 3: 16.9, 8/17/20: 16.6 after nine month hold, 8/24/20: 16.4, 8/31/20:16.2, 9/14/2020: 16.0, 9/21/20: 15.8, 9/28/20: 15.6, 10/19/20:15.4, 10/26/20: 15.2, 11/2/20: 15.1, 11/7/20: 14.8 

 

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Found this extensive article about stability of drugs in suspending agents like Ora Plus. It's a bit of a dense read but the basic take home message is that of the 60-something drugs reviewed only som

For anyone who feels their liquid is uneven and the pill just sinks to the bottom, Ora Plus works incredibly well at disbursing the pill evenly. I use 10 ml water and 10 ml Ora plus with my 20 mg of Paxil. I’m no longer worrying about it evenly dispersing. It’s clear as day that it works super well. 

2008: start Lexapro 10 mg which is quickly upped to 20 mg. 2008:2013 try at least four individual times to get off Lexapro, never get lower than 5mg, settle at 15 mg. 2015: again, attempt to get off Lexapro and get to 5 mg. After 6 months, feel i'm stabilizing but go back on a higher dose because of one stressful event. 2016: go to 20 mg from 15 mg due to work stresses, hit severe tolerance for the first time and become very suicidal. 2016-2017: try viibryd and cymbata in an attempt to feel better. Also add Lamictal 150 at some point. 2017: eventually land on paxil 37.5 and Lamictal 150. January 2018: cut paxil to 25. April-July 2018: reduce Lamictal in 50 mg increments till im off August. 2018: reduce paxil to 20 mg. december 2018: dropped Paxil to 18 mg, SEVERE CRASH. March updosed to 20 mg April 11: dropped to 19.4 mg due to akathsia (still experiencing akathsia symptoms from updose) April 20: 19 mg Paxil May 4: 18.7 Paxil July 5: 18.2 July 12: 17.8 Aug 19: 17.5 Aug 26: 17.3 Oct 20: 17.1 Nov 3: 16.9, 8/17/20: 16.6 after nine month hold, 8/24/20: 16.4, 8/31/20:16.2, 9/14/2020: 16.0, 9/21/20: 15.8, 9/28/20: 15.6, 10/19/20:15.4, 10/26/20: 15.2, 11/2/20: 15.1, 11/7/20: 14.8 

 

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thecowisback

ii noticed i was low down in the jar of liquid this morning and it tasted more bitter than usual as there was more powder at the bottom. i wonder if any of the moderators would know more about how much of this powder is filler - i'm sure someone told me on here somewhere that all the medicine dissolves and the powder that's left is filler. i tried tagging some mods but it won't let me send the post with the tags in it for some reason. 

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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Do you make your own liquid or get it at a pharmacy? 

2008: start Lexapro 10 mg which is quickly upped to 20 mg. 2008:2013 try at least four individual times to get off Lexapro, never get lower than 5mg, settle at 15 mg. 2015: again, attempt to get off Lexapro and get to 5 mg. After 6 months, feel i'm stabilizing but go back on a higher dose because of one stressful event. 2016: go to 20 mg from 15 mg due to work stresses, hit severe tolerance for the first time and become very suicidal. 2016-2017: try viibryd and cymbata in an attempt to feel better. Also add Lamictal 150 at some point. 2017: eventually land on paxil 37.5 and Lamictal 150. January 2018: cut paxil to 25. April-July 2018: reduce Lamictal in 50 mg increments till im off August. 2018: reduce paxil to 20 mg. december 2018: dropped Paxil to 18 mg, SEVERE CRASH. March updosed to 20 mg April 11: dropped to 19.4 mg due to akathsia (still experiencing akathsia symptoms from updose) April 20: 19 mg Paxil May 4: 18.7 Paxil July 5: 18.2 July 12: 17.8 Aug 19: 17.5 Aug 26: 17.3 Oct 20: 17.1 Nov 3: 16.9, 8/17/20: 16.6 after nine month hold, 8/24/20: 16.4, 8/31/20:16.2, 9/14/2020: 16.0, 9/21/20: 15.8, 9/28/20: 15.6, 10/19/20:15.4, 10/26/20: 15.2, 11/2/20: 15.1, 11/7/20: 14.8 

 

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thecowisback

i make my own. 

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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Me too. If you can afford the Ora plus and are stressing about dispersion, I highly recommend it. I have no idea if the sediment is filler or not, but the fact that it’s evenly mixed with the Ora eases my mind and is worth the money imo. 

2008: start Lexapro 10 mg which is quickly upped to 20 mg. 2008:2013 try at least four individual times to get off Lexapro, never get lower than 5mg, settle at 15 mg. 2015: again, attempt to get off Lexapro and get to 5 mg. After 6 months, feel i'm stabilizing but go back on a higher dose because of one stressful event. 2016: go to 20 mg from 15 mg due to work stresses, hit severe tolerance for the first time and become very suicidal. 2016-2017: try viibryd and cymbata in an attempt to feel better. Also add Lamictal 150 at some point. 2017: eventually land on paxil 37.5 and Lamictal 150. January 2018: cut paxil to 25. April-July 2018: reduce Lamictal in 50 mg increments till im off August. 2018: reduce paxil to 20 mg. december 2018: dropped Paxil to 18 mg, SEVERE CRASH. March updosed to 20 mg April 11: dropped to 19.4 mg due to akathsia (still experiencing akathsia symptoms from updose) April 20: 19 mg Paxil May 4: 18.7 Paxil July 5: 18.2 July 12: 17.8 Aug 19: 17.5 Aug 26: 17.3 Oct 20: 17.1 Nov 3: 16.9, 8/17/20: 16.6 after nine month hold, 8/24/20: 16.4, 8/31/20:16.2, 9/14/2020: 16.0, 9/21/20: 15.8, 9/28/20: 15.6, 10/19/20:15.4, 10/26/20: 15.2, 11/2/20: 15.1, 11/7/20: 14.8 

 

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I do half Ora 10 ml and half water. Being that the bottle contains over 400 ml, this will last me over 40 days. On amazon it’s like 25 bucks. Expensive, but not as much as paying like 250 a month for liquid paxil

2008: start Lexapro 10 mg which is quickly upped to 20 mg. 2008:2013 try at least four individual times to get off Lexapro, never get lower than 5mg, settle at 15 mg. 2015: again, attempt to get off Lexapro and get to 5 mg. After 6 months, feel i'm stabilizing but go back on a higher dose because of one stressful event. 2016: go to 20 mg from 15 mg due to work stresses, hit severe tolerance for the first time and become very suicidal. 2016-2017: try viibryd and cymbata in an attempt to feel better. Also add Lamictal 150 at some point. 2017: eventually land on paxil 37.5 and Lamictal 150. January 2018: cut paxil to 25. April-July 2018: reduce Lamictal in 50 mg increments till im off August. 2018: reduce paxil to 20 mg. december 2018: dropped Paxil to 18 mg, SEVERE CRASH. March updosed to 20 mg April 11: dropped to 19.4 mg due to akathsia (still experiencing akathsia symptoms from updose) April 20: 19 mg Paxil May 4: 18.7 Paxil July 5: 18.2 July 12: 17.8 Aug 19: 17.5 Aug 26: 17.3 Oct 20: 17.1 Nov 3: 16.9, 8/17/20: 16.6 after nine month hold, 8/24/20: 16.4, 8/31/20:16.2, 9/14/2020: 16.0, 9/21/20: 15.8, 9/28/20: 15.6, 10/19/20:15.4, 10/26/20: 15.2, 11/2/20: 15.1, 11/7/20: 14.8 

 

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thecowisback
  • i'm trying to find a similar item in the uk but i think it must be called something different over here 😊

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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There’s gotta be. Go to a compounding pharmacy and see what they offer 

2008: start Lexapro 10 mg which is quickly upped to 20 mg. 2008:2013 try at least four individual times to get off Lexapro, never get lower than 5mg, settle at 15 mg. 2015: again, attempt to get off Lexapro and get to 5 mg. After 6 months, feel i'm stabilizing but go back on a higher dose because of one stressful event. 2016: go to 20 mg from 15 mg due to work stresses, hit severe tolerance for the first time and become very suicidal. 2016-2017: try viibryd and cymbata in an attempt to feel better. Also add Lamictal 150 at some point. 2017: eventually land on paxil 37.5 and Lamictal 150. January 2018: cut paxil to 25. April-July 2018: reduce Lamictal in 50 mg increments till im off August. 2018: reduce paxil to 20 mg. december 2018: dropped Paxil to 18 mg, SEVERE CRASH. March updosed to 20 mg April 11: dropped to 19.4 mg due to akathsia (still experiencing akathsia symptoms from updose) April 20: 19 mg Paxil May 4: 18.7 Paxil July 5: 18.2 July 12: 17.8 Aug 19: 17.5 Aug 26: 17.3 Oct 20: 17.1 Nov 3: 16.9, 8/17/20: 16.6 after nine month hold, 8/24/20: 16.4, 8/31/20:16.2, 9/14/2020: 16.0, 9/21/20: 15.8, 9/28/20: 15.6, 10/19/20:15.4, 10/26/20: 15.2, 11/2/20: 15.1, 11/7/20: 14.8 

 

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thecowisback

we don't have one of those where i live 😑

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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I suggest you contact the manufacturer https://www.perrigo.com/default.aspx

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Current from 9 Jan 2021:  Pristiq 0.405 mg

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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thecowisback

just double checking my dosage. i was making liquid from 1 x 20mg capsule in 20ml of water and taking 5ml a day - 5mg prozac. the mixture was running out quickly so today i used 3 x 20 mg capsules in 60ml of water so i still take 5 ml to equal 5mg prozac? i'm sure that 's right but needed to double check 😉 @ChessieCat

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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thecowisback
On 5/2/2019 at 8:31 AM, thecowisback said:

just double checking my dosage. i was making liquid from 1 x 20mg capsule in 20ml of water and taking 5ml a day - 5mg prozac. the mixture was running out quickly so today i used 3 x 20 mg capsules in 60ml of water so i still take 5 ml to equal 5mg prozac? i'm sure that 's right but needed to double check 😉 @ChessieCat

@Altostrata

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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  • Moderator Emeritus
On 4/25/2019 at 7:09 AM, Adili13 said:

For anyone who feels their liquid is uneven and the pill just sinks to the bottom, Ora Plus works incredibly well at disbursing the pill evenly. I use 10 ml water and 10 ml Ora plus with my 20 mg of Paxil. I’m no longer worrying about it evenly dispersing. It’s clear as day that it works super well. 

 

This is what I've been doing as well, just in case there's any active ingredient stuck inside those tiny pill crumbs!  I also like that it makes a syrupy liquid rather than water, it seems easier to handle when measuring and when actually taking it.

2001–2002 paroxetine

2003  citalopram

2004-2008  paroxetine (various failed tapers) 
2008  paroxetine slow taper down to

2016  Aug off paroxetine
2016  citalopram May 20mg  Oct 15mg … slow taper down
2018  citalopram 13 Feb 4.6mg 15 Mar 4.4mg 29 Apr 4.2mg 6 Jul 4.1mg 17 Aug 4.0mg  18 Nov 3.8mg
2019  15 Mar 3.6mg  21 May 3.4mg  26 Dec 3.2mg 

2020  19 Feb 3.0mg 19 Jul 2.9mg 16 Sep 2.8mg 25 Oct 2.7mg 23 Oct 2.6mg 24 Dec 2.5mg

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Altostrata
On 5/2/2019 at 12:31 AM, thecowisback said:

just double checking my dosage. i was making liquid from 1 x 20mg capsule in 20ml of water and taking 5ml a day - 5mg prozac. the mixture was running out quickly so today i used 3 x 20 mg capsules in 60ml of water so i still take 5 ml to equal 5mg prozac? i'm sure that 's right but needed to double check 😉 @ChessieCat

 

The 20mL lasted you 3-4 days, correct?

 

60mL might last you 11-12 days. I would not keep a do-it-yourself liquid for more than maybe 4 days, it might go bad, even in the refrigerator.

 

Your math is correct but your technique is not recommended.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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thecowisback

ok, thankyou ☺

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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  • 3 weeks later...
thecowisback

I'm still having trouble getting the last bit of compacted powder out of the capsules. I've tried using as toothpick to scrape out the last bits but some still remains. If I put the capsule into the water to wash it out some powder sticks to the capsule when I remove it. Would it be ok to leave the empty capsule in the solution for the duration of the use of the liquid? 

 

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg

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  • 2 weeks later...

I'm trying to take small amount of lexapro, i have 10mg tablet, but feel I only need a minute dose.

 

0.5mg or 0.2mg based on the attached PDF which i made, it would think a 10-20% 5-HTT block would be enough to treat my symptoms as i continue to taper.

 

i have a digital scale, so I am thinking of crushing the 10mg tablet to powder and weighing out what would be 0.5mg/0.2mg, which would be micro dosing.

 

then i will put the powder into 10ml of water and swallow that, in that i dont need to dissolve it, but rather mix it to a larger volume to allow for ingestion rather than putting powder in mouth which might have no effect.

 

thanks

Doc2.pdf

Lexapro

10mg 11/2018 -  4 weeks

20mg 12/2018 - 4 weeks

20mg - 0mg - 01/2019 - 02/2019  - taper 6 weeks - WD symptoms

10mg - 03/2019 - 6 week reinstate

03-04/2019 taper 10,7.5,5,2.5,0mg as instructed by dr.

0mg - 04-06/2019 - WD symptoms again.

accute symptom cleared follow by protracted symptoms still ongoing

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brassmonkey

You would be working with a very tiny amount of powder and losing any of it would cause a large change in the strength of the dose.  If you try putting it into water there is a good chance that some will stick to the container and be lost.  There are several other ways that might work better.  Take a spoon of apple sauce or fruit jam and pour the powder on a pile on top of that and swallow it whole. Or take a very small piece of toilet tissue (single ply) and wrap the powder in that.  Make it into a tiny ball and swallow it whole with some water.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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nice thanks for the tip, i think i need a bit more paper in my diet so will take that option.

Lexapro

10mg 11/2018 -  4 weeks

20mg 12/2018 - 4 weeks

20mg - 0mg - 01/2019 - 02/2019  - taper 6 weeks - WD symptoms

10mg - 03/2019 - 6 week reinstate

03-04/2019 taper 10,7.5,5,2.5,0mg as instructed by dr.

0mg - 04-06/2019 - WD symptoms again.

accute symptom cleared follow by protracted symptoms still ongoing

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  • 4 weeks later...
swordiebrom

aren't you afraid of a relapse while you are tapering? i think i might have experienced a relapse of some sort or withdrawal,i  cant really tell, each relapse hurts my cognitive function

risperidone 5mg on 17 december 2017

4mg from 15/1/2018

3mg from 23/1/2018

2 mg from 27/3/2018

fluoxetine 20mg started 15/12/2017,stopped 15/1/2018

1/1/2019 80 mg lurasidone

2/1/2019 40 mg lurasidone

3/1/2019 stopped

29/5/2019 20 mg lurasidone 

7/6/2019 10 mg lurasidone 27/6/2019 5 mg lurasidone 30/11/2019 2 mg lurasidone 30/12/2019 1.66 mg lurasidone

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NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Current from 9 Jan 2021:  Pristiq 0.405 mg

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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  • Petunia changed the title to How to make a liquid from tablets or capsules
  • 1 month later...

I was wondering if tap water was OK to use to make my liquid or do I need to buy distilled water?

 

Ativan .5mg as needed from 1983-2014

Prozac 10mg 1993-1994 cold turkey

Nortriptyline 75mg 1994- 2014 Now I am on 10mg - have been holding at this dosage for 2 yrs. Presently wanting to finish my taper with water titration.

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I think tap water is okay.  However I think it would be better to use distilled water, bottled water or filtered water.

 

The unused portion needs to be refrigerated in a dark/tinted (preferably), covered container.

NEW!!!     INTERVIEW with Altostrata, SA's founder    NEW!!! 

 

REMINDER TO SELF:  I don't need the drug now, but my still brain does.

Current from 9 Jan 2021:  Pristiq 0.405 mg

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering Oct 2015 

My tapering program   My Intro (goes to my tapering graph)  My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions.

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Ok. Thank-you!

 

Ativan .5mg as needed from 1983-2014

Prozac 10mg 1993-1994 cold turkey

Nortriptyline 75mg 1994- 2014 Now I am on 10mg - have been holding at this dosage for 2 yrs. Presently wanting to finish my taper with water titration.

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  • 1 month later...
On 2/8/2014 at 1:50 PM, Ks1994 said:

I'd like to just add that if you switch from pill to liquid you likely should updose because your body will interpret it as a withdrawal. I could not stabilize on liquid and had to resort back to cutting/filing which is not as accurate unfortunately,

thats true. I was able to stabilize but I found that the dose changes depending on the kind of water you use. I noticed this with tap water vs filtered. I always used tap then the day I switched to filtered I went in withdrawal.. I think its because of the minerals in the water cause it to disperse differently

Withdrew from Luvox in 2015 to fast (took 2 months). (highest dose was 800mg..tapered off 50mg every week)

...
(Klonopin 1 mg for a month, second time on it, in May 2016 and tapered .25mg through early aug)
(Tapered off Klonopin as i went on Luvox)  
-Off klonopin-
....
Back on Luvox in 2016 of June..400 mg 8/26/2016.. 350mg 8/26/2016.. 300mg 09/04/2016.. 250mg 09/08/2016.. (tried to taper to 225mg 03/07/2017 didn't work).. 240mg  04/04/2017.. 230mg 04/27/2017.. 225mg 05/12/2017...223mg 09/28/2017...222mg 05/01/2018...220mg 05/21/2018...218mg 09/01/18...216mg 02/21/19  (03/15/2019-08/30/19)had a serve drug interaction with going into ketosis and an far infrared sauna.. took a long time to recover and find the right dose)  08/30/19...199mg...09/24/19...198mg (feeling more human)
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  • 3 weeks later...

Anyone use this stuff to make their suspensions? It's considerably cheaper than Ora Plus - looks like the same thing. Would it be ok?

 

https://www.amazon.com/gp/product/B0773N95JL/ref=ppx_yo_dt_b_asin_title_o00_s00?ie=UTF8&psc=1

2018 - Tried Sertaline, Lexapro, and Amitriptyline before settling on Remeron/Mirtazapine - 7.5 mg, October

2019 - Mirtazapine 15 mg - February

2019 Dec 30 - Started Mirtazapine taper 7.5mg

2020 Jan 24 - Tapered 13% to 6.5mg mirtazapine

 

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Hey all, so I've started emptying my 20mg fluoxetine capsules into 200ml of filtered water, to see if there is any difference in effect when taking the capsule straight up. 

 

I can feel a difference. I found the potency of the drug to be much less than when I take it via the capsule. Is that crazy? Could there be some degradation happening? I try to take it as soon as possible after mixing and with food in the morning. I am wondering if there is just a small amount of degradation, or maybe small amounts that are lost when I open the capsule (sometimes a small amount of powder gets on my hands). Also there is a bit of residue on the glass. I fill my container back up repeatedly until the taste is gone to get as much of the residue. 

 

I am wondering if either of these factors are contributing to lower dosage, and therefore the feeling of reduced potency, or if it is all in my head. Or maybe I am just this sensitive to even the smallest amount of change to the medications.

May 2017: Started 20mg fluoxetine for suicidal depression due to relationship issues

August 2017: CT'd the fluoxetine because I was feeling better

August 2017 to June 2019: Brutal withdrawal and discontinuation syndrome

June 2019: Started 50mg trazodone to help with insomnia

August 2019: Reinstated 20mg fluoxetine, using a different generic brand

January 2020: Doing better experiencing a reduction in withdrawal symptoms but a worsening of some other side effects. Looking to start a slow taper of fluoxetine.

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I’ve just read that Citalopram is insoluble in water? 

 

https://www.accessdata.fda.gov/drugsatfda_docs/label/2011/020822s038s040,021046s016s017lbl.pdf

 

How then, is it possible to make a liquid with it using water as the OP states? 

Past four years: Fluoxetine, 10mg; currently tapered down to 2.8mg. 

Diazepam, 5mg, once daily (goes up to 8mg sometimes during taper). 

1999-2016: Mainly sertraline but also Venlafaxine  and Paroxetine. 

31 Oct: discontinued Fluoxetine.

1 Nov 2019: started Sertraline, 12.5mg, once every two days. 

13 Nov 2019: Reinstated Fluoxetine due to adverse effects from Sertraline. Plan to start Citalopram once stabilised on Fluoxetine 

 

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You are correct Citalopram does not dissolve in water.  You have to do what is called a suspension, where you shake up the liquid every time just as you use it so the cloudy stuff is evenly distributed in the water.  You can also purchase a suspension medium, which is a thick syrup which holds the particles up so they don't settle out.  Or you could dissolve it in alcohol and then mix the alcohol with water. I think all three methods are discussed in this thread.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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I have ordered Ora-Plus to make my own suspensions at home.

 

With 1x 50mg tablet and Ora-Plus to make a 1mg=1ml solution, that would make a batch that would cover about 17 days at my current dose. I see that the consensus here at SA seems to be to discard after a week or less. If I'm going to discard after a week, it will become an expensive exercise.

 

It looks as though, in my country, if a suspension is made up by a compounding pharmacy, it seems that a standard use by date may be 28 days. It's obviously hard to determine, but I have also heard from my local pharmacy that if they make me up a suspension, that they think the use by date is longer than that - for my particular drug and their particular suspension vehicle - I don't know what it is so, but it's definitely not Ora-Plus as that's not available here. (Mine is coming from the US.)

 

So, my 17 days' worth of suspension is obviously shorter than that 28 days. I'm wondering if it is worth an experiment on my part to push it a bit further, given that I'd be using the proprietary suspension formula, would disinfect everything I use, use cooled boiled water if I decide to dilute, can keep in the dark in the fridge etc.

 

Any thoughts? Do we know why the thought here at SA is to only keep home made suspensions for such a short time?

2005 St John's Wort / 2006-2012 Lexapro 20mg, 2 failed attempts to stop, tapered over 4.5 months in early 2012

January 2013 started Sertraline, over time worked up to 100mg

July 2014 Sertraline dropped from 100mg to 75mg, held for six months, slower tapering until 2019 22 Dec 3.2mg

2020 Sertraline 19 Jan 3.1mg, 26 Jan 3.0mg; 1 Mar 2.9, 7 Mar 2.8, May (some drops here) 24 May 2.5, May 29 2.4, June 21 2.3, June 28 2.2mg,  July 4 2.1mg, July 24 (or maybe a bit before) 2mg, early Nov switched to home made suspension; 29 Nov 1.8mg; approx 25 Dec 1.6mg)

 

My thread here at SA: https://www.survivingantidepressants.org/topic/1775-bubbles/page/17/

CurrentSertraline: 24 Dec 2020 1.6 mg / Armour Thyroid / endless allergy meds, erg

 

 

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  • 3 weeks later...

Hi all - on my long slow micro taper I have  been having brand Lexapro compounded. The compounding pharmacy uses a slow release filler - Methocel E4M.  I am down to  0.1 mg and they cannot make capsules at lower doses. They offered an aliquot (10 caps of 0.01 mg ea) which I tried and my brain went sideways for months. I switched back to the individual capsules of 0.1 mg.  I have gained some stability but seem to be experiencing both w/drawal and side effect symptoms.  Over the yrs of my taper the side effect symptoms were always what prompted me to make a reduction.  And i feel i need to do that soon.

Unfortunately the filler Methocel E4M is not water soluble. it clumps up and really sticks to the side of the glass.  Very hard to make a suspension. it only dissolves in very hot water but I dont want to do that.

So I had the pharmacy make me 0.1mg caps in Methocrystalline cellulose which dissolves nicely in water but is fast release. I am trying to transition over by taking it (capsules for now with the idea of dissolving in water later) every 3 days but already feeling w/drawal aggravation.  Not sure how to do this?

Is there a way to make a suspension with the slow release Methocel E4M filler?

Or should I go more slowly with the transition from the slow release to fast release capsules?

Any ideas would be very helpful!

Thank you!

Poke

7 yrs Lexapro 10 mg. Mar/2011 - 1 month taper. Severe W/D. Multiple symptoms.Gallbladder and parathyroid surgery in Aug and Oct. Disability 3 months.  Dec/2011 reinstated 5mg Lex and went back to work. very bad shape.

By Aug/2012 - self tapered to 1.25 mg cutting pills. -very bad shape. Nov/2012  Dr. Hinz neuro-replete. up and down. Aug/2013 at aprox 1.0 mg Lex stopped neuro-replete ~Oct 2013 Found this site  ~ began using compounded Lexapro and have been micro tapering since then and holding as needed.

11/6/2013 -  0.6 mg

2/1/2018 - .135 mg  Now reducing 5-10% per month 

4/1/18 - .1 mg

4/17/18 - changed delivery from compounded individual caps to aliquot. went from .1 mg to .09 aliquot

7/4/2018 - .09 mg Holding due to wave of W/D symptoms

7/22/18 updosed to .1 mg aliquot

9/30/18 - reduced to .0975 aliquot

2/1/19 - updosed to .1 mg aliquot due to instability bad wave W/D

9/12/19 - back to .1 mg individual caps since could not get stable using aliquot

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On 3/31/2020 at 3:59 PM, Pokeshaw said:

Hi all - on my long slow micro taper I have  been having brand Lexapro compounded. The compounding pharmacy uses a slow release filler - Methocel E4M.  I am down to  0.1 mg and they cannot make capsules at lower doses. They offered an aliquot (10 caps of 0.01 mg ea) which I tried and my brain went sideways for months. I switched back to the individual capsules of 0.1 mg.  I have gained some stability but seem to be experiencing both w/drawal and side effect symptoms.  Over the yrs of my taper the side effect symptoms were always what prompted me to make a reduction.  And i feel i need to do that soon.

Unfortunately the filler Methocel E4M is not water soluble. it clumps up and really sticks to the side of the glass.  Very hard to make a suspension. it only dissolves in very hot water but I dont want to do that.

So I had the pharmacy make me 0.1mg caps in Methocrystalline cellulose which dissolves nicely in water but is fast release. I am trying to transition over by taking it (capsules for now with the idea of dissolving in water later) every 3 days but already feeling w/drawal aggravation.  Not sure how to do this?

Is there a way to make a suspension with the slow release Methocel E4M filler?

Or should I go more slowly with the transition from the slow release to fast release capsules?

Any ideas would be very helpful!

Thank you!

Poke

 

Escitalopram has a half life of somewhat over 24 hours, you could switch to twice a day liquid dosing to stabilize the blood concentrations more. You wouldn't have been able to make a liquid from the methocel E4M solution even if it hadn't clumped up because you would have lost the slow release.

The only way I can think you can transition from slow release to fast release is if you take the 0.01mg aliquots every 2.4 hours and then reduce the time between them until you are taking 10 aliquots at once, then you can direct swap to 0.1mg IR/liquid. You would have to set an alarm at night though. You could try taking them every 1.6 hours for the 16 hours you're awake but there will be a bigger immediate adjustment before you can shrink the schedule.

Dx: complex PTSD

Discontinuation/taper history: sertraline, trazodone, prazosin, mirtazapine, diazepam

Took 200mg quetiapine for 0.5 years and 150mg for 1.5 years until 01/2020. Now microtapering daily at an overall rate of 12.5mg/month.

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Hi LX - Thanks for getting back to me.  I can't use the liquid since it only comes in generic and I had a bad reaction to it back a few yrs ago. I have been using brand Lexapro for the compounding. Also, I had tried the aliquot the pharmacy made for me over a year ago and was not able to stabilize on it so I went back to individual caps of 0.1 mg

 

Here's what I've been doing - and so far so good.

 

for a couple weeks I took the 0.1 mg fast release every 3 days and the other days I stayed with the 0.1 mg slow release. It was a bit bumpy as I mentioned in my post but then that passed. So I waited a few days and then I moved to every other day and that is where i am now. Doing OK 

Will stay here another week or so and then when I feel OK go to daily on the fast release. Will stay there until I feel pretty stable before starting to dissolve in water and do reductions.

One of the big 'side effect' issues for me that always indicated it was time to make a reduction is the 'lexapro clench'. Neck arms jaw and all the issues that ensue such as carpal tunnel, nerve pain and TMJ.  all stuff i suffered with along with constipation when I was on full dose of Lexapro and all went away when i stopped. unfortunately i stopped too fast and then went into a horror show of w/d. Then reinstated months later and have been on this seesaw of tapering and dealing with w/d and side effect symptoms for yrs. This final stretch is very hard! But good to have someplace to check in where people have a clue about this!

I have ordered a graduated cylinder and some oral syringes and have been reading about how to do it. But I'm sure I will post again once i get to the dilution phase.

Take good care and thank you again for responding!

Poke

7 yrs Lexapro 10 mg. Mar/2011 - 1 month taper. Severe W/D. Multiple symptoms.Gallbladder and parathyroid surgery in Aug and Oct. Disability 3 months.  Dec/2011 reinstated 5mg Lex and went back to work. very bad shape.

By Aug/2012 - self tapered to 1.25 mg cutting pills. -very bad shape. Nov/2012  Dr. Hinz neuro-replete. up and down. Aug/2013 at aprox 1.0 mg Lex stopped neuro-replete ~Oct 2013 Found this site  ~ began using compounded Lexapro and have been micro tapering since then and holding as needed.

11/6/2013 -  0.6 mg

2/1/2018 - .135 mg  Now reducing 5-10% per month 

4/1/18 - .1 mg

4/17/18 - changed delivery from compounded individual caps to aliquot. went from .1 mg to .09 aliquot

7/4/2018 - .09 mg Holding due to wave of W/D symptoms

7/22/18 updosed to .1 mg aliquot

9/30/18 - reduced to .0975 aliquot

2/1/19 - updosed to .1 mg aliquot due to instability bad wave W/D

9/12/19 - back to .1 mg individual caps since could not get stable using aliquot

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  • 1 month later...

Don't you know that cipralex is soluble in water?

 

MOD NOTE:  This is incorrect.  Please see this post: 

 

 

Edited by ChessieCat
added mod note

2011-2019 április cipralex 10mg 

2019 május 7,5 

2019 június 5 mg 

2019. június 26. Boom (depresszió, álmatlanság, verejtékezés, adhedonia, üres elme)

2019. június 26. - most 10 mg (adhedonia, szorongás)

2020.11.05.  5 mg 😁😁

 

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brassmonkey

Sorry Johni, but that isn't true.  According to rxlist.com 

 

 Escitalopram oxalate occurs as a fine, white to slightly-yellow powder and is freely soluble in methanol and dimethyl sulfoxide (DMSO), soluble in isotonic saline solution, sparingly soluble in water and ethanol, slightly soluble in ethyl acetate, and insoluble in heptane. (RED highlight added)

 

Your best bet would be to use a homemade isotonic saline solution (9% salt in water) as methanol is poisonous and DMSO is hard to get and hard to work with.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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