PortugueseSea Posted October 15, 2022 Share Posted October 15, 2022 It seems that my inflammatory markers are a bit on the high end and that would potentially warrant an anti inflammatory supplement. I have been suggested Vitamin B6, Vitamin E, CoQ10 and sulforaphane by a friend knowledgeable about akathisia and withdrawal. Anybody has any experience with these and how did you take them? Thanks! December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN. March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg). April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol. May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound. May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. June 2023 - Added fish oil.Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2 Intro thread: https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/ Link to comment Share on other sites More sharing options...
EttaLouWho Posted October 20, 2022 Share Posted October 20, 2022 @PortugueseSeamine are high too. I was thinking about curcumin. Let me know what you decide to do. 1995 Prozac 1996 Prozac and Paxil 1997 Celexa 1998-2018 Cymbalta 60-120mg-- failed taper and restarted at 20mg after development of intense rage--finally able to taper off in late 2018 2017-2021 Clonazepam 0.5mg BID--discontinued over 4 weeks in April 2021 resulting in severe benzo withdrawal for 5 months maybe still ongoing at time of AD rapid taper in Dec 2021 2018-2019 Bupropion *Have been polydrugged since 1995 with a variety of benzos, sleeping pills, anxioltyics, and ADs. Too many to list or remember. Never properly tapered by doctor before switching medicines* 2020 Started on Buspirone 15mg three times a day 2020-2021 Antidepressant was changed three times: Trintellix, Pristiq, Fluvoxamine. Underwent 6 months of ketamine infusions. Advised to discontinue all meds due to inefficacy in November 2021. Weaned off Fluvoxamine by psychiatrist over 6 weeks-- last dose ~December 10, 2021. Severe ongoing withdrawal. February 2021 Started on 300mg Gabapentin for anxiety, restless legs, insomnia, and wide spread body pain from withdrawal. Began Gabapentin taper to 200mg on 8/5/2022. Worsened withdrawal symptoms. Also began 2000mg of L-Tryptophan for depression/AD withdrawal, 2400mg of N Acetyl Cysteine for OCD and 300mg of Magnesium for depression. Began L-Tryptophan taper from 2000mg to 1500mg on 8/14/2022. Completed l-tryptophan and NAC taper on 8/29/2022. Current Meds: 15mg of Buspirone twice a day (morning and night since 2020), 5 mg Buspirone at midday (Started taper of midday dose from 15mg to 5 mg in September 2023) , 200mg of gabapentin at night (Since August 2022), 1mg of alprazolam at night (Started at 0.25mg in Jan 2023 and gradually upped to 1-2mg three times a week until end of 11/2023--reinstated 1mg daily on 12/1/2023), 80mg propranolol in the morning, 10mg Zyrtec in the morning, birth control pills Current Supplements: 300 mg of magnesium citrate midday, 1000mg of Fish Oil in the morning, 1mg melatonin at night Link to comment Share on other sites More sharing options...
PortugueseSea Posted October 25, 2022 Author Share Posted October 25, 2022 I am thinking Vitamin E but given that I just recently changed my magnesium, I am dosing twice a day now, will probably wait a bit before starting! 1 December 2021 - Metoclopramide started. Akathisia symptoms start; Metoclopramide gets changed to PRN. March 2022 - Akathisia diagnosed; Metoclopramide stopped; Propranolol 10mg x twice a day. Biperiden PRN (0.5mg to 1mg). April 2022 - Tandospirone 30mg (10mg 3x day), Quetiapine 25mg (only taken once, immediate adr). Mirtazapine 7.5mg. . Discontinued Propranolol. May 2022 - Mirtazapine upped to 15mg. Tandospirone cut to 2x 10mg. Low dose Depakote for the month; 100 to 200 to 100 to 0. Mirtazapine cut back to 11.75mg (3/4 of a 15mg pill).June 2022 - Mirtazapine updose to 15mg. Tandospirone, Biperiden discontinued. Klonopin started PRN (0.5mg). September 2022 - Akathisia slowly starts improving, WD/ADR normal sets in in mid September. Hold for 4 months.March 2023 - Off mirtazapine; no Klonopin for 5 months either! Started quercetin (250mg x 2) to soften the histamine rebound. May 2023 - Stopped quercetin and changed from magnesium carbonate to oxide - reacted badly. Reverted back to carbonate. June 2023 - Added fish oil.Current regimen: CALM Magnesium (Carbonate into Citrate) 175mg x2; Vitamin E 268mg x2; Fish oil (100mg Omega3; EPA 30mg; DHA 37mg)x2 Intro thread: https://www.survivingantidepressants.org/topic/27095-portuguesesea-metoclopramide-akathisia-and-mirtazapine/ Link to comment Share on other sites More sharing options...
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