Jump to content

PatriciaAnn Doxepin Taper


Recommended Posts

I have been on Doxepin 40 mgs for Chronic Fatique Syndrome/depression for 35 years.  I am now a senior and have been experiencing brain fog.  I have recently started reducing my dose ever so gradually with the goal to reach a maintenance dose of 30 mgs by summer.

Was put on Doxepin 40 mgs to treat Chronic Epstein Barr Virus in 1986. Have been as high as 75 and back down with no problems. Tapering now to 30 mgs.


Started 1/10/23 at 37.5 mgs.  10 mg capsule mixed in 1 oz of water, pouring out 1/4 oz.  Today is 1/28.  Intend to wait until fully adjusted to reduce anymore. 

Link to comment
  • Shep changed the title to PatriciaAnn Doxepin Taper
  • Administrator

Hi, @PatriciaAnn.


Welcome to Surviving Antidepressants.


Here is some information to get you started:


Tips for tapering doxepin (Sinequan, Zonalon)

Why taper by 10% of my dosage?


The Windows and Waves Pattern of Stabilization



Healing from antidepressants. Patterns of recovery  video (4 minutes)


It's possible that some of your chronic fatigue symptoms are the results of long-term antidepressant drugging. As you reduce, moving towards your target maintenance dose, you may want to keep going until you're completely off these drugs. 


This is one theory:


Now Antidepressant-Induced Chronic Depression Has a Name: Tardive Dysphoria


We also know the outcomes for depression used to be much better before the antidepressant era:


Long-term Evidence We Can’t Overlook Anymore: Anti-Depressant Outcomes


Anyways, just some thoughts. Very glad you're here to learn more and to work on reducing your drug burden. 



Is Doxepin the only drug you're currently taking? Please set up a signature. Here is how:


How to Summarize Your Drug History in Your Signature


After you set up your signature and we know more about your drug history, we'll be able to provide more targeted advice. 


Drug free May 22, 2015 after 30 years of neuroleptics, benzos, z-drugs, so-called "anti"-depressants, and amphetamines 


My Success Story:  Shep's Success: "Leaving Plato's Cave"


And what is good, Phaedrus, and what is not good — need we ask anyone to tell us these things? ~ Zen and the Art of Motorcycle Maintenance

I am not a medical professional and this is not medical advice, but simply information based on my own experience, as well as other members who have survived these drugs.


Link to comment

Create an account or sign in to comment

You need to be a member in order to leave a comment

Create an account

Sign up for a new account in our community. It's easy!

Register a new account

Sign in

Already have an account? Sign in here.

Sign In Now
  • Create New...

Important Information

Terms of Use Privacy Policy