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GiaK

Histamine food intolerance

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Meimeiquest

Hi B, I appreciate all your comments...I am jumping off atenolol this weekend and not able to think in complex ways, but I will write in my thread about it when I am able. Appreciate you!

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btdt

Please be very careful with this drug.  Atenolol is a trickster it was for me one 25 mg. I could not tell you if it was too high a dose or if coming off is worse than being on it.. as I could not tolerate the one pill I took.  Please ask advice about this medication from the moderators maybe they will have some ideas for you.  

I don't know enough to be helpful in any way other than to say what I have.  It was not good for me may work for others I don't know.

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btdt

Hi B, I appreciate all your comments...I am jumping off atenolol this weekend and not able to think in complex ways, but I will write in my thread about it when I am able. Appreciate you!

Your drug history does not show Atenolol.  Are there other drugs your taking that are not on the list... it may be important.  I see your on toprol... not sure what that is but think I seen it on a lawyer website I was at yesterday about paxil and aorta stuff... what is it?

It may be important to check for drug interactions if your on a lot of different drugs just to be safe.

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btdt

It is an enormous conundrum...people who are sick don't have money. Doctors with unusual ideas aren't covered by insurance. So sick, broke people should take conventional meds. Dr. Walsh (a chemist, not a doctor) is actually speaking to the APA in upcoming weeks. He needs funding for double-blind studies which they haven't been able to afford. I thought about trying to figure it out myself, but I just can't. Personally, I wouldn't think much of it, but as I read of it, I saw that my sister's doc has used this method, and has taken her off 17 years of Prozac with a two week taper....and it apparently worked!

Do you have a first name for this Dr Walsh to cut down my research time?  Is it Darren?

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Meimeiquest

It is the Walsh Institute in Illinois. He has written a book called Nutrient Power. And you are right, nothing explains the whole "recipe." They are all infomercials to make you willing to spend the money.

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btdt

Thanks his name is William J Walsh.

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btdt

Interesting Walsh apparently holds a few patents.. different articles state 3 - 5 -then 40 patents. I can't seem to find out what they are just yet.

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btdt
"On June 6, 2013 at 12:35 am Lisa said:

One interesting thing about high (blood) histamine level is that it is a marker of low methylation status. So nutrient therapies to boost methylation can lower your histamine level. Then you don’t have to police your food intake of histamines so much…"


 


"I need to avoid high amine foods and find that any probiotics I take make all my symptoms return, particularly severe bone and joint pain. I have read that others have had the same problems, I recently read about a low histamine prebiotic that some have had success with. I’ve ordered it, but haven’t tried it. Would be handy to help the digestive track guys out since they produce MAO, which helps you handle more histamines."


"On October 29, 2013 at 11:04 am Lisa said:


Here’s what we’ve used successfully. I’d like yo know the name of the one you’re now trying. We have Prescript Assist. Using it for about 6 weeks now. I heard about it on a histamine blog. It has multiple “traditional” species & strains otherwise found only in fermented/curried foods. We had to cut back and ramp up more slowly than we started. I have also found the following to be excellent for gut healing, but they only have a single species, specially prepared. We use it regularly for years now. It was the THE thing that got me headed out of a histamine-overload leaky gut crisis: Intelac (by Fuma Natural) and Russian Choice (by Allergy Research Group). Developed by the same doctor, They have the same probiotic and herb, but Intelac also has digestive enzymes."


 


I am back on antibiotics and found this information about probiotics increasing histamine... and this one that apparently does not raise histamines... tho it has other thinkgs.  Again I am not recommending anything I have not tried and I have not tried this it is here for your  information and consideration only.  


All this is from the amine sensitivity page... here


http://aminerecipes.com/what-are-amines/

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GiaK

prescript assist did not work for me ...made me flare just like every other probiotic i've taken. also when I've tried to take supps that affect methylation I've also reacted badly. supps are almost completely out for me these days. I'm dong okay with herbs...I make teas...buy herbs in the bulk section so they're pure and have no additives.

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btdt

prescript assist did not work for me ...made me flare just like every other probiotic i've taken. also when I've tried to take supps that affect methylation I've also reacted badly. supps are almost completely out for me these days. I'm dong okay with herbs...I make teas...buy herbs in the bulk section so they're pure and have no additives.

Could I ask which herbs you use and what you they help with?  

Do you know anything about the  Intelac ?

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GiaK

I wrote about it here: http://beyondmeds.com/2014/06/01/herb-list/ that's not an exhaustive list...

 

I have found out that several of them do affect histamine release in mast cells...and that's why they're likely so helpful. I really have to rotate though and sometimes stop them...and also sometimes take tiny doses...lots of listening to the body.

 

as far as Intelac...it doesn't seem to explicitly breakdown all the ingredients and I don't generally take any supps at this point with multiple ingredients in any case...so I can't comment on what it is really. Also I don't do well with any probiotics at this time. It looks potentially interesting otherwise...

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btdt

thanks

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NoMeaning25

Gia, does the anti-histamine diet help clear candida?

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GiaK

no, not necessarily...although there is likely a lot of crossover...so it could very well help...

 

still if you have issues with candida I'd also be sure to cover your bases for those eliminating those specific foods as well...(until you heal)

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Emely

Hello Gia,

 

A doctor recommended me the Paleo/ Autoimmunprotocoll....I did a Histamintesting and my test was ok... But I don´t know if I have Histaminintolerance...

 

Always when I try to start the Paleo diet I began not to feel so well , but I did not do it for some months so I don´t know if this was just the beginning problem.

I was so excited cause I thought this will help, cause I had a thyroid treatment and also since this time I feel not good...

But now after all the psychdrugs I got , I really feel worse. I have problems interacting with people and just go out .. I was a very social person....

 

so did you also take Seroquel ? this also lowers the Histamin and to come off is so difficult.

 

I also did a lot of Hormontesting and this was also not good, but not really tried all the hormones. So did you had hormonproblems ?

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GiaK

yes...seroquel is one of the most potent antihistamines among the psych drugs. 

 

we all have hormone issues I think once our bodies get messed up from drugs.

 

changing diet is a long-term adventure...that's how I've come to view it...take baby steps and try not to attach yourself to any particular protocol...learn from all of them and it's all about trial and error...it's taken me years to develop my diet and understanding around it's importance. 

 

we are all unique and therefore any given protocol is at best only a system from which to learn from. there are 100s of diets out there that claim to bring us to well-being...they may be all right for someone, but they are not right for everyone, so unless we're lucky and find a protocol that happens to fit us exactly, we have to work at finding out own protocol.

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Emely

Thanks for your answer :)

 I will see the next weeks again if Paleo makes me feel worse ( then I really have problems with the Histamin)

So how are you now ?? with the diet that fits to you ? Did you also know something about the liver flush ? I did it now 2 times and after this the next 3 days I really felt a lot better.... So I think my liver is also in a bad shape after all these bad drugs..

 

How long did you take the drugs ? I just read that you took 6 years to come off !! Wow that´s a long time !

How did you feel before ? Do you also were an activ person ? I not really understand why all my emotions for people are so flat and usually I really enjoyed being around people... also laughing was one of the things i really liked and did.....

 

So I not really know is this really withdrawel or just my hormones that changed so bad in the last years ....do you also do something for your adrenals to help them. Maybe the issue is also adrenal fatigue after all those years( and that is my theory , cause usually I could come off the meds really quickly without any w/d) But since  I take Thyroxin for the thyroid everything changed and the sympoms were risen. Especially the depression in the morning and the feeling of not wanting to go out or be surounded by people...

 

So the doctor said the Paleo diet will help the thyroid condition and the autoimmuncondition...I really hope so....

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GiaK

getting healthy slowly over time often corrects hormone and endocrine issues -- not always, but often...think globally...like just go for overall good health...I'm starting to be menopausal, so that does make things more complicated, yes.

 

I took six years because I came of 6 drugs at very high doses. I was on drugs for 20 years.

 

I became very sick, but I had a very extreme history...most people don't get sick like I do.

 

adrenal support is best done very cautiously...most adrenal supplements will be too much...this is an article that refers to issues with adrenals...Alto wrote most of it...but I talk about my experiences too

 

Withdrawal syndrome vs adrenal fatigue

http://beyondmeds.com/2012/01/03/adrenalvswithdrawal/

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Emely

Thanks Gia !

 

wow so sorry for you what happened to you !! Did you never thought in all those 20 years to come off them ?? Or did you tried it and it did not work...

 

I read the article about the adrenal support ... A lot of people who take the cortisol have success with it especially if you have problems with your thyroid, also taking the right amount of hormones.. I allready took some Cortisol last year and the first weeks I felt so much better , but then after some weeks it change and I stopped taking it. other adrenal complex also not really worked and I got more Derealistion.... 

 

So what do you think about fasting ? Is this also dangerous if you taking drugs or you are in withdrawel.. Just today a friend called me and she said that she feel so fantastic with fasting..i never tried this cause i thought if you are taking the medication during the fasting the body can´t detoxify....

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GiaK

fasting is fine when it's appropriate...it's often NOT appropriate when one is in withdrawal...mostly not appropriate would be my guess with the caveat that we're all different....so there is always room for exceptions...

 

we all have to cautiously find our own way with this stuff. 

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GiaK
from David Healy's withdrawal guide...he doesn't understand the potential extent of it (and I do not recommend the drugs he suggests), but this is interesting...
 

Having said this, SRI dependence and withdrawal does involve real bowel disturbances 
from diarrhea through to food intolerance that are difficult to see just as a vigilance 
problem and there is much more serotonin in the gut and muscles than anywhere else. 
 
Stabilizing the histamine system - 1 
The SRIs are a group of antihistamine drugs that also inhibit serotonin reuptake. Despite 
marketing propaganda, they are not selective or clean drugs. 
 
One way to manage withdrawal might be to switch to an SRI antihistamine such as 
chlorphenamine or diphenhydramine. These are less potent SRIs and switching to them is 
a way to slowly reduce the dose. 
 
A related option here is to switch to a tricyclic antidepressant such as dosulepin which is 
also an antihistamine with less potent serotonin reuptake inhibiting properties. 
The best way to think about this is that the SSRIs are like sports cars that can pick up pace 
incredibly quickly but a car like this isn’t needed in a town or a city. The amount of 
serotonin and reuptake inhibition from dosulepin or chlorphenamine is all that is really 
needed for most situations. 
 
There are other antihistamines that do not inhibit serotonin reuptake such as loratadine or 
cetirizine that might be useful if withdrawal comes more from histamine than serotonin. 
 
Stabilizing the histamine system - 2 
A further option on the antihistamine front is to view serotonin withdrawal as a histamine 
over-activity (semi- allergic) state brought around by the fact that the person has been on 
antihistamines chronically. 
 
One of the ways to damp down histamine over activity is to use a mast cell stabiliser such 
as sodium chromoglycate. Sodium chromoglycate (Nalcrom) is used extensively for people 
with food intolerance – a complaint that many people with SRI withdrawal have. 
 
The histamine system can be further damped by adding a H2 receptor blocker such as 
cimetidine or ranitidine. 
 
Cinnarizine is an antihistamine that is also a calcium channel blocker. 

 

 

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Altostrata

Hmmm, at least he's given some thought to it from a psychopharmacologist's point of view.

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btdt

 

from David Healy's withdrawal guide...he doesn't understand the potential extent of it (and I do not recommend the drugs he suggests), but this is interesting...
 
Having said this, SRI dependence and withdrawal does involve real bowel disturbances 
from diarrhea through to food intolerance that are difficult to see just as a vigilance 
problem and there is much more serotonin in the gut and muscles than anywhere else. 
 
Stabilizing the histamine system - 1 
The SRIs are a group of antihistamine drugs that also inhibit serotonin reuptake. Despite 
marketing propaganda, they are not selective or clean drugs. 

 

One way to manage withdrawal might be to switch to an SRI antihistamine such as 
chlorphenamine or diphenhydramine. These are less potent SRIs and switching to them is 
a way to slowly reduce the dose. 

 

A related option here is to switch to a tricyclic antidepressant such as dosulepin which is 
also an antihistamine with less potent serotonin reuptake inhibiting properties. 
The best way to think about this is that the SSRIs are like sports cars that can pick up pace 
incredibly quickly but a car like this isn’t needed in a town or a city. The amount of 
serotonin and reuptake inhibition from dosulepin or chlorphenamine is all that is really 
needed for most situations. 

 

There are other antihistamines that do not inhibit serotonin reuptake such as loratadine or 
cetirizine that might be useful if withdrawal comes more from histamine than serotonin. 
 
Stabilizing the histamine system - 2 
A further option on the antihistamine front is to view serotonin withdrawal as a histamine 
over-activity (semi- allergic) state brought around by the fact that the person has been on 
antihistamines chronically. 

 

One of the ways to damp down histamine over activity is to use a mast cell stabiliser such 
as sodium chromoglycate. Sodium chromoglycate (Nalcrom) is used extensively for people 
with food intolerance – a complaint that many people with SRI withdrawal have. 

 

The histamine system can be further damped by adding a H2 receptor blocker such as 
cimetidine or ranitidine. 

 

Cinnarizine is an antihistamine that is also a calcium channel blocker. 

 

 

 

http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682543.html

chlorphenamine 

NO longer sold OTC 

diphenhydramine - Benadryl or Unisom I know this is sold still. 

http://www.nlm.nih.gov/medlineplus/druginfo/meds/a682539.html

Same thing for both... yet the 

 

other one suggest and stated not to affect serotonin?  I wonder about this.

 

"There are other antihistamines that do not inhibit serotonin reuptake such as loratadine or 

cetirizine that might be useful if withdrawal comes more from histamine than serotonin. "
 

Loratadine - Wikipedia, the free encyclopedia

en.wikipedia.org/wiki/Loratadine
  •  
  •  
 

Loratadine (INN) is a second-generation H1 histamine antagonist drug used to treat allergies. In structure, it is closely related to tricyclic antidepressants, such as .REACTIN

more from wiki

Loratadine (INN) is a second-generation[1] H1 histamine antagonist drug used to treat allergies. In structure, it is closely related totricyclic antidepressants, such as imipramine, and is distantly related to the atypical antipsychotic quetiapine.[2]

Loratadine is marketed by Schering-Plough[needs update] under several trade names (e.g., Claritin) and also by Shionogi in Japan. It is available as a generic drug and is marketed for its nonsedating properties. In a version named Claritin-D or Clarinase, it is combined with pseudoephedrine, a decongestant; this makes it useful for colds, as well as allergies but adds potential side effects of insomnia,anxiety, and nervousness.

http://en.wikipedia.org/wiki/Loratadine#Cautions_and_contraindications

(I have personally reacted badly to both of these suggestions very badly.... 

The histamine system can be further damped by adding a H2 receptor blocker such as 
cimetidine or ranitidine. 

 

Cinnarizine is an antihistamine that is also a calcium channel blocker.") 
 
I would not recommend any of it... bit curious about the one... " mast cell stabiliser such 
as sodium chromoglycate. Sodium chromoglycate (Nalcrom)"  if mast cell destabilization is an issue of withdrawal what else does it cause that we are already suffering... for me this is the only useful bit of this article.  
Nice to have him chime in I guess.
Think I will look up mast cell destabilization.... to satisfy myself. 
Take the walk with me if you like... all guessing and google btw
"Mast cell stabilizers are cromone medications used to prevent or control certain allergic disorders. They block a calcium channel essential for mast cell degranulation, stabilizing the cell and thereby preventing the release of histamine[1]"
CC that is interesting. 
Go ahead join here or start another thread... not nice to play too long in somebody else's thread. 
Nalcrom wiki
""Cromolyn works because it prevents the release of mediators that would normally attract inflammatory cells and because it stabilizes the inflammatory cells. MCT mast cells found in the mucosa are stabilised."[6] Nedocromil is another mast cell stabilizer that also works in controlling asthma. The underlying mechanism of action is not fully understood; for while cromoglicate stabilizes mast cells, this mechanism is probably not why it works in asthma.[7] Pharmaceutical companies have produced 20 related compounds that are equally or more potent at stabilising mast cells and none of them have shown any anti-asthmatic effect.[7] It is more likely that these work by inhibiting the response of sensory C fibers to the irritant capsaicin, inhibiting local axon reflexes involved in asthma, and may inhibit the release of preformed T cell cytokines and mediators involved in asthma. (see review by Garland, 1991)

It is known to somewhat inhibit chloride channels (37% ± 7%)[8] and thus may inhibit the:

  • exaggerated neuronal reflexes triggered by stimulation of irritant receptors on sensory nerve endings (e.g. exercise-induced asthma)
  • release of preformed cytokines from several type of inflammatory cells (T cellseosinophils) in allergen-induced asthma

Note: Another chemical (NPPB: 5-nitro-2(3-phenyl) propylamino-benzoic acid) was shown, in the same study, to be a more effective chloride channel blocker.

Finally it may act by inhibiting calcium influx.

Cromoglicate is classified as a chromone.

Cromolyn is also being tested as a drug to treat insulin-induced lipoatrophy"

All interesting hints. 

Even more curious now.

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btdt

These mast cell stabilizer drugs seem to stop arthritis in mice... I think... bit too stupid today to read it right... 

http://www.ncbi.nlm.nih.gov/pubmed/17530709

If your brain is working read it and tell if that is right or not.

 

basics here hope to come back on a better day and follow this up

http://en.wikipedia.org/wiki/Mast_cell#Autoimmunity

I do that a lot and forget.

Peace folks.

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GiaK

I'm doing a post on this...for the blog...will post on monday most likely...

 

most of us sensitive folks I've worked with in histamine groups do really badly with most of pharma...so I really think the drugs are only for emergency and crisis. 

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btdt

I took a small just to see what effects come from mast cells that are behaving badly... and found this

http://www.mastocytosis.ca/signs.htm

 

Mastocytosis 

Initially, only a few signs and symptoms may be present. Especially if diagnosis takes several years, the signs and symptoms escalate in type, severity, frequency and persistence, eventually leading to permanent disability or death. Listed below are 58 signs and symptoms reported to us by patients consistently over the past 10 years.
  • skin lesions or sores
  • skin rash, spots, redness
  • hives
  • persistent fatigue
  • itching
  • flushing & severe sweating
  • joint, bone pain
  • headaches
  • tachycardia (racing heartrate)
  • eyes tearing/dry, eye pain
  • persistent body/tissue pain
  • difficulty exercising
  • vertigo
  • episodes of low body temperature
  • unexplained Vitamin B12 deficiency
  • scents/odors/chemical reactions
  • difficult menses (females)
  • numbness & tingling 
    in face and extremities
  • skin feels on fire
  • unexplained anxiety
  • sudden drops in blood pressure
  • fainting
  • persistent diarrhea
  • vomiting
  • unexplained weight loss
  • cognitive impairment
  • sinus problems
  • chest pain
  • vision problems
  • hair loss
  • mouth sores
  • nausea
  • swelling & inflammation
  • odd reactions to insect stings
  • anesthesia difficulties
  • anemia
  • thyroid problems
  • decreased bone density
  • unexplained weakness
  • shortness of breath
  • sunlight sensitivity
  • temperature (hot/cold) sensitivity
  • difficulty with foods, drinks
  • anaphylactoid reactions
  • anaphylaxis
  • gastrointestinal pain, bloating
  • unexplained medication reactions
  • enlarged liver/spleen
  • liver/spleen/bladder/kidney pain
  • enlarged lymph nodes
  • frequent urination
  • recurring infections
  • neuropathic pain
  • constipation (MCAS)
  • iron deficiency
  • unexplained bruising, bleeding
  • malabsorption
  • intermittent tinnitus or hearing problems

If it had bad reaction to Vitamin D brain zaps and a few other things on that list I would say this is what I have... and maybe I do... or is that googlitis again... 

 

You have to admit a lot of what we know of as withdrawal is on the list. 

I know reaching again but maybe the answer is at the end of one or two of these reaches.   Now I wonder what effect ssir snri drugs have on mast cells if any.  The article says this disorder thought rare is making a remarkable climb and researchers are trying to catch up. 

peace all

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btdt

I looked up the drug to treat mast cell disorder induced depression - it says it treats it at a link I will put at the bottom...

 

Masitinib
From Wikipedia, the free encyclopedia
 
 
220px-Masitinib.svg.png Systematic (IUPAC) name 4-[(4-Methylpiperazin-1-yl)methyl]-N-(4-methyl-3-{[4-(pyridin-3-yl)-1,3-thiazol-2-yl]amino}phenyl)benzamide Clinical data Trade names Masivet, Kinavet AHFS/Drugs.com International Drug Names Legal status ? Identifiers CAS number 790299-79-5 ATC code L01XE22 PubChem CID 10074640 ChemSpider 8250179 Chemical data Formula C28H30N6OS Mol. mass 498.64 g/mol

Masitinib is a tyrosine-kinase inhibitor used in the treatment of mast cell tumors in animals, specifically dogs.[1][2] Since its introduction in November 2008 it has been distributed under the commercial name Masivet. It has been available in Europe since the second part of 2009. In the USA it is distributed under the name Kinavet and has been available for veterinaries since 2011.

Masitinib is being studied for several human conditions including cancers. It is used in Europe to fight orphan diseases.[3Mechanism of action[edit]

Masitinib inhibits the receptor tyrosine kinase c-Kit which is displayed by various types of tumour.[2] It also inhibits the platelet derived growth factor receptor (PDGFR) and fibroblast growth factor receptor (FGFR).[citation needed]

link

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3198767/

 

found that link on this site

http://mastcelldisorders.wallack.us/yabb/YaBB.pl?num=1333922422

 

wish I was smarter and had an education... peace all

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btdt
Nonimmunologic Histamine Releasers - and - Other Degranulation Triggers2
Polymers Dextran Compound 48/80 Calcium ionophore A23187 Bacterial Toxins Snake venoms Biologic polypeptides Ascaris species Jellyfish Portuguese man-of-war Spines & hairs of Caterpillars Nettles Moths Foods Shellfish, Any fish not fresh Strawberries Egg Whites Tomatoe Nuts (peanuts, walnuts etc.) **Download our diet guideline. Chemicals & Drugs Aspirin Alcohol Opiates (Codeine,Morphine,Percocet/Oxy etc) NSAIDs (Non-steroidal anti-inflammatories: Advil,Motrin,etc) Polymyxin B sulfate Colistin sulfate Thiamine hydrochloride Tyramine Trimethaphan and Trimetaphan Tubocurarine chloride Quinine sulfate Papaverine Dipyridamole (Persantine) Iodine based radiographic dyes Scopolamine hydrochloride Gallamine triethiodide Neuromuscular blocking agents (all):eg.,
  • Dexamethonium
  • Gallamine triethiodide
Dextromethorphan (cough suppressant) Stilbamadine isethionate Chlortetracycline bisulfate Amphetamines Hydralazine hydrochloride Tolazoline hydrochloride Cinnamaldehyde Cinnamic acid Benzoic acid Sodium benzoate Fungal infection drugs Local anesthestics: lidocaine,etc.(any amino amide-type)
  • Perfume, Man-made materials, Scented products, Chemicals
  • High in Histamine or Tyramine, Gluten, Soy, Salicylates
Physical Agents Dermatographia (Darier's Sign) Pressure Cold Heat Cholinergic agents
  • Exercise, hot baths/showers, fever, occlusive dressings,
    eating spicy foods, emotional stress
Solar light waves Water Vibration Insect bites (Wasp, Hornet, Bee, Mosquito) Infections Inhalants Scents/Odors, Smoke (wood burning, cigarette, marijuana) Latex Foods (**Download our diet guideline.) Cosmetics/Creams containing salicylates Preservatives, Additives, Dyes, Artificial flavours/colouring Vasculitis Internal diseases

 

Contact Agent Triggers of Skin Reactions2
Acrylic monomer Aminothiazole Ammonia Animal Dander Cat and Dog Saliva Arthropods Benzophenone Benzoyl peroxide Carrots Castor beans Cephalosporins Cetyl alcohol Chlorpromazine Cobalt chloride Cod liver oil Diethyltoluamide Estrogenic creams Exotic woods Flour Formaldehyde Hair sprays Horse serum Lindane Monoamylamine Nail polish Penicillin Perfumes Phenylmercuric propionate Platinum salts Potatoes Silk Sodium sulfide Spices Stearyl alcohol Streptomycin Sulfur dioxide Taliphatic polyamide Tetanus antitoxin Wheat Wool

http://www.mastocytosis.ca/symptoms.htm

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GiaK

Here is my latest update from the blog:

 

Have you considered histamine intolerance associated with psych drug use and withdrawal?

http://wp.me/p5nnb-b8I 

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Altostrata

That is an excellent blog post, thank you, Gia.

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btdt

Here is my latest update from the blog:

 

Have you considered histamine intolerance associated with psych drug use and withdrawal?

http://wp.me/p5nnb-b8I 

In reading your link noticed you did not address the Mast cell issue brought into this conversation by Dr Healy  so I guess you think it is insignificant. Is this true do you have anything at all to say about it?

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GiaK

I don't understand your question.

 

The post was all about how very significant the issue is.

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btdt

Maybe it is I that does not understand... he talked of a drug to help that involved mast cells. 

I did not see mention of mast cell or the drug to treat this issue in your post.

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GiaK

My general thesis is that drugs aren't generally the best way to treat mast cell...diet and lifestyle changes are preferable in the long run.

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btdt

My general thesis is that drugs aren't generally the best way to treat mast cell...diet and lifestyle changes are preferable in the long run.

Thank you.  Do you know and could you explain the relationship between mast cells and histamine.  As I do not see it.  As I thought I am missing a link between the two. 

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