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PubMed, a site sponsored by the U.S. National Library of Medicine National Institutes of Health (NIH), is a centralized collection of scientific papers published in recognized journals from all over the world.

 

The search tool is easy to use. For example, enter "venlafaxine withdrawal syndrome" and you will get more than 80 results:

 

http://www.ncbi.nlm.nih.gov/pubmed?term=venlafaxine%20withdrawal%20syndrome

 

(Venlafaxine is the pharmacological name for Effexor; use the pharmacological terms rather than brand names for better results.)

 

The results are mostly abstracts or summaries of the journal articles. In some cases, free full text is attached, or you might find free full text on other sites by Googling. If you really want an article, you usually can buy it from the journal publisher for $15-$25.

 

The abstracts and articles are written in scientific language and may be difficult to interpret. Do not jump to conclusions upon reading an abstract -- often you need to read the entire article, with a medical journal handy, to understand what the authors are really saying.

 

Even then, many studies of psychiatric drugs are funded by pharmaceutical companies and may be more positive about drug effectiveness and adverse effects than warranted by the data or by related studies.

 

Usually, you have to read several related studies to get a more complete picture.

 

Despite the pro-drug propaganda that tends to be embedded in these studies, antidepressant adverse effects and withdrawal syndrome have been documented for 30 years.

 

If you find interesting studies in PubMed, please start a topic and post links at least to the abstracts in this forum.

Edited by Altostrata
fixed link

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Brandon

Surviving-

 

That is a good resource. Thanks for sharing... I do worry about the influence of big pharma with those studies and the potential and often prevalent underlying pro-drug sentiment. There is ambiguity and such to be found in the literature which as you stated can sometimes be hard to interpret. Often times there are conflicting statements as well.

I will definitely use the site as a reference point... and try to read into what they are saying as best as I can...

My brain is still in a fuzzy, hard to concentrate/comprehend point at this time however.

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Altostrata

You don't have to be fair. Just use the studies that support your point -- that's what researchers do.

 

And don't forget product inserts with black-box warnings about prescribing for children. They are available from the pharma companies. For example, Effexor XR package insert labeling.pfizer.com/showlabeling.aspx?id=100


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Altostrata

US Food and Drug Administration

 

Information about the US Food and Drug Administration's Adverse Event Reporting System (AERS)

http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/default.htm .

 

AERS statistics available at

http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/ucm070093.htm

 

Index to Drug-Specific Information

http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm111085.htm#P

 

FDA adverse events database

 

The FDA collects adverse events reports, such as antidepressant withdrawal syndrome, but has no way to mine them. (I believe you can request a raw download, but you need to put the info in a very large database to derive reports from it. I don't know how to request the raw data.)

 

A private company has made some basic reports from the FDA database available for free:

 

AdverseEvents.com: Retrieve statistics about adverse events from psychiatric drugs

 

PubMed

http://www.ncbi.nlm.nih.gov/pubmed/

 

US Clinical Trials registry

http://www.clinicaltrials.gov

 

Drugs@FDA

http://www.accessdata.fda.gov/scripts/cder/drugsatfda/

 

NIH RePORTER

http://projectreporter.nih.gov/reporter.cfm

 

Dollars for Docs on Propublica http://projects.propublica.org/docdollars/

Edited by Altostrata
updated

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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erer

  • 2,5 years of slowly tapering down Cymbalta from 60 mg. Then tried going from 8,44 mg to 1 mg in 8 days. (April 1st 2015). That's when the real hell started. Reinstated. Didn't help. I was added Ativan (2 mg 2 times a day for relentless akathisia that started with jumping Cymbalta). For years had been taking Zopitin 7,5 mg and Stilnox 10 mg for I had not been able to sleep naturally since the 1st day I started Cymbalta). Used to take Xanax occasionally.
  • All of the above were stopped cold turkey when I was hospitalized in the beginning of May 2015.
  • Prior to that I have been on and off the whole spectrum of different AD-s for 15 years (since I was 17).

My introduction.

 

Tapering:

  • Olanzapine (starting point 2,1 mg): Jan 2016  /---/ April 2018 0 mg. (From 2,1 mg to 0 mg in 1y 3mo).
  • Diazepam (starting at 5 mg) : switching to liquid May 2018;  4,6 mg (June 2018) /---/ 0 mg (Feb 2020) (From 10 to 5 - nobody knows, from 5 to 0 in 1 y 10 mo)
  • Valdoxan (starting at 25 mg): switching to liquid (Feb 2019) /---/ 12,5 mg (Feb 2020)

 

Supplements: D3, turmeric, probiotics, magnesium threonate + glycinate, B12+folate, omega 3.

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btdt

I can't sort out how to use it... can't find a thing but I am not the smartest person here and not in top form... have you been able to make any use of it?


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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InvisibleUnless

you have to put in the extant link, DOI, or other concrete reference to what you are trying to access.  sometimes it will only pull up the publicly shared abstract, like on pubmed articles with nothing further available, but sometimes you can access the full-page texts, pdfs, or other materials that normally throw up the "you must have a subscription!" dialogue.

 

i dont know what it does, or how widely applicable it is.  i would have to read more about it and experiment.  make sure you are allowing the scripts/cookies/whatnot that it requires to run (but dont trust those scripts/cookies/etc blindly!).


from 2005-2012, i spent 7 years taking 17 different psychotropic medications covering several classes.  i would be taking 3-7 medications at a time, and 6 out of the 17 medications listed below were maxed or overmaxed in clinical dosage before i moved on to trying the next unhelpful cocktail.
 
antidepressants (SSRIs, SNRIs, NDRIs, tetracyclics): zoloft, wellbutrin, effexor, lexapro, prozac, cymbalta, remeron
antipsychotics (atypical): abilify, zyprexa, risperdal, geodon
sleep aids (benzos, off-label antidepressants & antipsychotics, hypnotics): seroquel, temazepam, trazodone, ambien
anxiolytics: buspar
anticonvulsants: topamax
 
i tapered off all psychotropics from late 2011 through early 2013, one by one.  since quitting, ive been cycling through severe, disabling withdrawal symptoms spanning the gamut of the serious, less serious, and rather worrisome side effects of these assorted medications.  previous cross-tapering and medication or dosage changes had also caused undiagnosed withdrawal symptoms.
 
brainpan addlepation

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btdt

thanks IU I don't know cookies.. I eat them... I don't know scripts that for a movie right?  See I have no business even using a computer as I have no clue how they work.... but thank you for your efforts I will leave it alone. 


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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InvisibleUnless

haha, just internet browser muckery.  if you need any studies mined, PM me links/DOIs and i can see what comes up.


from 2005-2012, i spent 7 years taking 17 different psychotropic medications covering several classes.  i would be taking 3-7 medications at a time, and 6 out of the 17 medications listed below were maxed or overmaxed in clinical dosage before i moved on to trying the next unhelpful cocktail.
 
antidepressants (SSRIs, SNRIs, NDRIs, tetracyclics): zoloft, wellbutrin, effexor, lexapro, prozac, cymbalta, remeron
antipsychotics (atypical): abilify, zyprexa, risperdal, geodon
sleep aids (benzos, off-label antidepressants & antipsychotics, hypnotics): seroquel, temazepam, trazodone, ambien
anxiolytics: buspar
anticonvulsants: topamax
 
i tapered off all psychotropics from late 2011 through early 2013, one by one.  since quitting, ive been cycling through severe, disabling withdrawal symptoms spanning the gamut of the serious, less serious, and rather worrisome side effects of these assorted medications.  previous cross-tapering and medication or dosage changes had also caused undiagnosed withdrawal symptoms.
 
brainpan addlepation

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btdt

haha, just internet browser muckery.  if you need any studies mined, PM me links/DOIs and i can see what comes up.

oh my even thinker into the weeds....

 

Data mining is a process used by companies to turn raw data into useful information. By using software to look for patterns in large batches of data, businesses can learn more about their customers and develop more effective marketing strategies as well as increase sales and decrease costs.

 

I know pharma does it with doctors and us to sell us more drugs... 

 

how could we use this to our benefit... what the heck is a DIO ok stop being lazy

digital object identifier (DOI) is a unique alphanumeric string assigned by a registration agency (the International DOI Foundation) to identify content and provide a persistent link to its location on the Internet. The publisher assigns a DOI when your article is published and made available electronically.

 

A message given to a Web browser by a Web server. The browser stores the message in a text file. The message is then sent back to the server each time the browser requests a page from the server. Also see session cookie and persistent cookie.....guess I am the browser right

 

script...

In computer programming, a script is a program or sequence of instructions that is interpreted or carried out by another program rather than by the computer 

 

You challenge me to learn but it is not getting in just standing at the door knocking and knocking... I don't know if it is drug damage or stupidity... 

Guess I am a bit closer to some form of understanding....

long ago when I thought I was going to heal fast I thought I would return to school and study computers and chemistry... 

 

Now I just want to get thru life without too much grief... funny what long term suffering can do to a persons plans. I truly make no plans as who knows how I will feel that day. 

Thanks for the help IU


WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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emilie
On 2/13/2016 at 12:03 PM, erer said:

 

 

the link is now: 

http://sci-hub.tw/

note the fonction search works better if you use the addon for chrome browser.

 

more about the website here: 

https://en.wikipedia.org/wiki/Sci-Hub

 

 

i know another website that is https://vdocuments.site

 

i had good results with this type of search in google :

 

"title of the article" pdf

or

"title of the article" acknowledgements

or 

"title of the article" results 

or 

"title of the article" site:https://vdocuments.site

 

there is often a section results or aknowledgements in complete articles. with or without "s"

 

 


(i am french)

1998 prazépam, citalopram /1999 paroxetine prazepam /2000 paroxétine /2001venafaxine, alprazolam, clomipramine * 2002 (dont remember)/2003 clomipramine, alprazolam /2004 clomipramine /2005 alprazolam /2006(dont remember) * 2007citalopram, alprazolam, prazépam, venlafaxine /2008(dont remember) /2009 venlafaxine /2010 venlafaxine *All precedent withdrawal were very fast. I tried many times to stop but didn't know what happened. *2011 mirtazapine (22,5 mg) , norset , risperdal (cold turkey for risperdal and norset, analysis by doctor say that my body does not support and i was in danger) /2012 mirtazapine / 2013 mirtazapine  *october 2014 mirtazapine (15mg) - putting down slowly.   *when i was good for one month i  down 1ml. (1ml of 100ml of water in which there was 1 pill of 15mg of mirtazapine. At the end i remove 1ml of 50ml of water but with 0,5 pill it does the same concentration.) (i down more like "how i feel, because at the beginning i had a calendar tapping 10% every 15 days and i was really bad, so i decided to see one month and after if i was trust in my body, i remove 10% of the dose at the beginning; and at the end i remove 1ml (when the 10% was lower than 1ml). It was more how i feel. (it is just the last 1 ml that i remove rapidly because i think i was attached mentally and i need to break. and 1ml of 50ml of 15/2mg is just 1ml correspond to 0.15mg. ).  -juillet 2017 stop all. 

nov 2017 tetany and gastritis. I found "euphytose", "spasmine", "phyto-stress" from Govital(the more efficient if crisis because more concentrated)  efficient. If very bad i take valerian extract 1000mg (stop crisis). I have iron deficiency and osteoporosis (36 years old) Bone like a 80 years old.  2020: Often crisis at sunset. (spasmophilia, tetany, tremor, contractions, internal vibration ), insomnia, fundal gastritis and erythematous antral gastritis. hypotension low blood pressure.

 

 

 

 

 

 

 

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Itzakadoozee

There is an app on the I phone called “Researcher” to look up academic papers with ease for any one interested.


2005-2015 sertaline, 2015 to November 2018 escatalopram. Used liquid titration to drop doses. By 0.5mg at first then drops as small as 0.01mg at end of taper. Jumped of at 0.02mg

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Katy398

Hi @Altostrata

How can I tell which research has been Peer Reviewed? Or do you only post Peer Reviewed studies? 

Thanks again for keeping this site going. The wealth of information on here seems second to non!


 

Lexapro Fast Track/ Cold Turkey

Last dose end Dec 2018 

Tapered 1/2 a daily dose a week (20mg) for  14 weeks, last dose was a 20 mg pill!!  

 3.5 times slower than Psychiatrist recommended, I felt proud of myself!! Little did I know!!!!Got too scared to reinstate because I’d left it too long.

On ADs for 20 years (Prozac approx 10 years/ Pristiq approx 3 years/ Citalipram approx 2 years/. Lexapro a approx  5 years/. Last two years 40mgs Lexapro day.

 

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Altostrata

Scientific journals are generally peer-reviewed. As far as I know, almost everything we have is peer-reviewed. We might have a few doctoral theses in draft form, before they have been reviewed.


This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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