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Tips for tapering off Zyprexa (olanzapine)


Altostrata

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@Spideygsm that abrupt withdrawal must've been dreadful.  I remember occasionally when I missed a dose at 10mg I'd spend the next day basically staring into the void.  It would be debilitating having to deal with those large cuts and not catch up.

 

I chucked up some of my dose the other night (upset stomach) and from 1.1mg the next day really wasn't that bad by comparison.  A bit like land is in sight on this long voyage.  Those days where I miss a dose are quite infrequent but they have given a window into how far is left to go.  What would happen after a few weeks if I CT'd even here is still not worth thinking about!

 

You've done well to persist through that.  They should've cut the Ritalin as soon as you reported sleep problems.  I don't think stimulants have any place around children in any case. 

 

You're absolutely right about the need to address the underlying problems.  In my intro thread I went through how EMDR last year unearthed some horrible trauma from when I was 4.  A big upheaval but very liberating.  I'm happy I'll be ok from here, just a pity I didn't get that kind of help much sooner.

 

Agree on the exercise and diet, too.

 

Cheers

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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I'm kind of out of it right now and need to go to bed, but I just wanted to toss in my usual bit on the subject of making preparations for liquid tapering, which is: I personally don't worry about sol

Hi Lauren,   I'm a Zyprexa survivor...it can be done! Why don't you write a full intro with signature in the intro and update forum, especially if you are on other meds. I've made a lot of mistak

Just an update. I made a liquid solution with water and the orodispersible tablet. It forms a perfectly even solution so a daily taper should be accurate.

Leaving pills in the open

I have read medicenes lose effectiveness after some time. So i have some olanzapine pebbles left in open for some time. They lost some colour. Assuming it interacts with air and oxidises, would that decrease the potency of it? Which would benefit when reinstating? Or some random effect happens then its a bad idea.

 

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  • 1 month later...
On 12/23/2013 at 12:52 PM, Meimeiquest said:

Hi Lauren,

 

I'm a Zyprexa survivor...it can be done! Why don't you write a full intro with signature in the intro and update forum, especially if you are on other meds. I've made a lot of mistakes along the way, but tapering Zyprexa first was, for me, the most serious of them. I'm assuming you read this thread on Zyprexa tapering?

Hi @Meimeiquest, I am just about to begin my tapering process off Zyprexa 5mg. What method did you use to taper off Zyprexa? Thanks so much 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020 (current) 

75mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020 (current) 

Supplements: Elevit (multivitamin) 

 

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  • 2 weeks later...

Hi hayduke how you going?  just been reading people who have tapered off zyprexa, old posts but good to read...and one guy got me thinking...i know hard to do i zyprexa..lol..anyway.  I remember i tried dissolving for a duration of approx 3 weeks 2.5mg of zyprexa into water and drinking all of it, and i found i couldnt sleep...i do not know why as it is the same amount of a solid...however i was thinking...i pulled apart a capsule magnesium tablet and discarded its contents and i was thinking if i brought a micro scale, crush the tablet up on a piece of paper and pour it into the empty capsule casing, i could swallow it like it was a tablet...i know its fidely but i would aleast feel i am consuming the solid form....does that sound like a silly thing to do?  let me know cheers morgana

Diagnosed with Depression, Borderline Personality Disorder and Schizo-effective Disorder. 

Cipramil  40mg  1996 to October 2017 stopped cold turkey

Zyprexa 10mg solid form  1996 to October 2017

Zyprexa 7.5mg solid form  October 2017 to October 2019

Zyprexa 5mg solid form  October 2019 to April 2020

Zyprexa 3.75mg solid form April 2020 to May 2020

Zyprexa 2.5mg solid form  May 2020 to September 2020

Zyprexa 2.5mg liquid form September to Mid October 2020 - couldnt sleep

Zyprexa 2.5mg solid form  Mid October 2020 to 10 Nov 2020

Zyprexa 2.5mg solid 3/4 and liquid form 1/4  11 Nov 2020 to present

Supplements:  B complex, Multi vitamin, Omega fish oil, Magnesium 

 

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Hey Morgana.

 

Less a matter of silly than it's not that practical, I found

 

First, listen to your body.  For all the science around this stuff, and it's marvellous when it's as objective and humanist and untainted as it can be, it doesn't account for consciousness, and how you feel at any given moment is probably more to the point than some graph in  a paper somewhere.

 

Getting into your body is really important, yoga, exercise, fresh air, scenery, good food & company...we're animals first and rational second.

 

If you can't sleep after changing to a liquid, theory doesn't matter.  Being attuned to what your body needs does.  So take your time!

 

The liquid form is superficially impractical but in practice I found it way easier than weighing or measuring out powder.  It's 10-100x more accurate as a rough estimate, no matter how good your scales are.  I use a pipette, inexpensive on flea bay, but if I'm staying somewhere else a 50-60ml syringe will be ok for 3 days or so.

 

Splitting pills is even more inaccurate, it got me down to 5mg but was useless after that.

 

When you're feeling steady you could try introducing liquids again. 

 

And hey it's your taper, you're in control.  If you want to try weighing out the solid form give it a go.  If it sucks after say 2 nights just revert to where you were and hold till it's all ok again

 

Cheers

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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3 hours ago, morgana said:

I remember i tried dissolving for a duration of approx 3 weeks 2.5mg of zyprexa into water and drinking all of it, and i found i couldnt sleep...

Morgana, you said you couldn’t sleep dissolving the tablets. 
 

Unfortunately, that’s one of the biggest things any of us who’ve gotten of of Zyprexa have had to endure. For me, the two hardest things were not sleeping for months and anxiety. 
 

I think you’re doing really well. You’re at 2.5 mg. The toughest time for me was when I went below 2.5 mg. I quartered the pill with a pill cutter (not very accurate) but it ultimately worked. I’m not gonna sugar coat it. I felt horrible. It took about 4 months after my last does of Zyprexa until I started to feel better. Since stopping Zyprexa, my weight has come back to normal, my sleep has improved, I don’t feel like a zombie all day long, and the underlying health issues caused from Zyprexa side effects have gone away. 
 

Nobody wants to endure sleeplessness or psychological pain. Believe me when I say it’s temporary and it’s worth the torture of getting off Zyprexa. Exercise helps a lot. I swam and still swim today.

 

Hang in there. My recommendation to anybody stopping Zyprexa is don’t take it or stay on it just  because of lack of sleep. At some point we have have to stop, take the final dose. The body and mind will freak out. A few month of anxiety and no sleep are a small price to pay for how much better you’ll feel once the withdrawals stop. For me, one night I slept 4 hours and the anxiety was mostly gone. It continued to get better from that point on. Small ups and down but nothing like being on Zyprexa. 
 

Hang in there and good luck. You’re very close to being done

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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thanks spideygsm it isnt easy, my body feels like its been hit by a bus and has felt like this for nearly

1 1/2 years now, i have been on 2.5mg for 6 months now, i wake up every morning with back pain...i lay in my bed like a 'stiff board' all night, even though i am reducing my medication i have put on 10 kilos. i will hang in there for me their is no other option but to continue going further to hopefully eventually be off it completely...thanks for your support...cheers morgana

Diagnosed with Depression, Borderline Personality Disorder and Schizo-effective Disorder. 

Cipramil  40mg  1996 to October 2017 stopped cold turkey

Zyprexa 10mg solid form  1996 to October 2017

Zyprexa 7.5mg solid form  October 2017 to October 2019

Zyprexa 5mg solid form  October 2019 to April 2020

Zyprexa 3.75mg solid form April 2020 to May 2020

Zyprexa 2.5mg solid form  May 2020 to September 2020

Zyprexa 2.5mg liquid form September to Mid October 2020 - couldnt sleep

Zyprexa 2.5mg solid form  Mid October 2020 to 10 Nov 2020

Zyprexa 2.5mg solid 3/4 and liquid form 1/4  11 Nov 2020 to present

Supplements:  B complex, Multi vitamin, Omega fish oil, Magnesium 

 

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thanks hayduke, i will will just stick to 2.5mg solid for another six months, and think about what i will do when i feel i am ready.....i know i am not ready to change anything at the moment...just reading peoples posts got me thinking....cheers

Diagnosed with Depression, Borderline Personality Disorder and Schizo-effective Disorder. 

Cipramil  40mg  1996 to October 2017 stopped cold turkey

Zyprexa 10mg solid form  1996 to October 2017

Zyprexa 7.5mg solid form  October 2017 to October 2019

Zyprexa 5mg solid form  October 2019 to April 2020

Zyprexa 3.75mg solid form April 2020 to May 2020

Zyprexa 2.5mg solid form  May 2020 to September 2020

Zyprexa 2.5mg liquid form September to Mid October 2020 - couldnt sleep

Zyprexa 2.5mg solid form  Mid October 2020 to 10 Nov 2020

Zyprexa 2.5mg solid 3/4 and liquid form 1/4  11 Nov 2020 to present

Supplements:  B complex, Multi vitamin, Omega fish oil, Magnesium 

 

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  • 2 months later...
Bobblehead

Thanks for sharing your experience @Spideygsm I'm in a situation similar to yours, a high dose of Olanzapine (40mg) for a long time (17 years). After a 4 year taper I'm currently in my 6th week without Olanzapine and like you the anxiety and especially the insomnia are my main problems. It's good to read recovery stories, I don't know if I will ever recover but I hope I start feeling better in a few months.

2004 - 2020: Olanzapine 40mg for schizophrenia (Started to taper in 2016, completely off December 2020, still have withdrawals)

2004 - present: Lorazepam/Clonazepam 1mg as needed, rarely use them

2004 - 2012: Venlafaxine 75mg for depression

2008 - present: Metformin 2000mg for diabetes

2008 - 2013: Lipitor 40mg for high cholesterol

2008 - 2018: Bezalip 400mg for high triglycerides

2013 - present: Crestor 40mg, 20mg and now 10mg for high cholesterol

2016 - present: Forxiga 10mg for diabetes

2020 - present: Lurasidone 60mg for schizophrenia

2020 - present: Various supplements (100mg 5-HTP, 100mg l-theanine, 500mg GABA, Jamieson Herbal Complex (Relax and Sleep), 500mg Vitamin C, 400 IU Vitamin D, 12.5mg Zinc picolinate , 5mg Melatonin, CalmAid, 10mg CBD, 100mg l-theanine)

 

I've tried some other drugs short term but discontinued them early due to side effects. I can't remember all their names, antidepressants and antipsychotics, was only on them for a week or so.

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Spideygsm

Bobblehead,

 

Congratulations! Hang in there because the very worst part should be behind you. As I recall my horrific insomnia continued for about 12 weeks past my final dose. I used CBD at night but I don’t know if it’s what helped, the placebo effect, or my mind was finally starting to recover.

 

I started sleeping better (but not great) but during the days I started feeling, not living in the Zyprexa fog. I just slowly got better over time. I would feel better for a few days than like crap for a couple days but you’ll definitely know you beat the devil. Start doing any type of exercise you can. The added weight came off and it’ll restore your energy and help with your sleep. I took about a year after my last dose I didn’t feel any more I’ll effects from a drug that should be illegal to prescribe. 
 

I would guess at any day you’ll start to get periods of feeling better. Even a little bit feels great and you’ll be so thankful. 
 

Hang in there. The journey is at its end. Life will change for the best. Keep us informed. I’m exited to hear your reaction

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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Hi and thanks for the congrats @Spideygsm I do have some good days. It's just this damn insomnia.

 

Do you remember what kind of CBD you used to help you sleep? Was it a pure extract? A full spectrum CBD? Did it have THC in it, if so a little or a lot? Do you remember the dosage you where taking? How long before bed you took it?

 

I have pure CBD oil I take sublingually in the morning, it helps relax me, it doesn't contain anything else in it like full spectrum CBD does and it doesn't contain any THC in it either.

 

Just wondering what you were using?

 

Thanks

2004 - 2020: Olanzapine 40mg for schizophrenia (Started to taper in 2016, completely off December 2020, still have withdrawals)

2004 - present: Lorazepam/Clonazepam 1mg as needed, rarely use them

2004 - 2012: Venlafaxine 75mg for depression

2008 - present: Metformin 2000mg for diabetes

2008 - 2013: Lipitor 40mg for high cholesterol

2008 - 2018: Bezalip 400mg for high triglycerides

2013 - present: Crestor 40mg, 20mg and now 10mg for high cholesterol

2016 - present: Forxiga 10mg for diabetes

2020 - present: Lurasidone 60mg for schizophrenia

2020 - present: Various supplements (100mg 5-HTP, 100mg l-theanine, 500mg GABA, Jamieson Herbal Complex (Relax and Sleep), 500mg Vitamin C, 400 IU Vitamin D, 12.5mg Zinc picolinate , 5mg Melatonin, CalmAid, 10mg CBD, 100mg l-theanine)

 

I've tried some other drugs short term but discontinued them early due to side effects. I can't remember all their names, antidepressants and antipsychotics, was only on them for a week or so.

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Hi Bobblehead,

 

As I recall, it was pure CBD with no THC. I think I took 10mg at bedtime. I didn’t start taking it until about 3 months or so after my last dose of Zyprexa. 
 

I wouldn’t swear either way if it was the CBD or just a placebo effect. If it helps you I say go for it. I have always been a poor sleeper. I keep a sleep log. Last week I averaged 3.1 hours of sleep per night. I slept a little better while I was on Zyprexa but I didn’t feel rested at all. 
 

Insomnia was the worst withdrawal symptoms I had. But as the anxiety and my head became clearer, I felt better and the severe zero sleep insomnia got better. Again, my sleep was very poor before Zyprexa. You’ll get better. I know how it is. When it’s you not sleeping and going through withdrawals, it seems like it’ll never end but it does. I’m so happy I got through it. You’re so close. Don’t give up hope. 
 

You got this!

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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Hi,

 

I havent been around lately but yr  comments regarding CBD interest me.

Talking about CBD, well I have been taking it for a month. But recently I decided to do it differently in order to cope with the mornings and this terrible cortison anxiety spiral which has left me with a terrible noise sensitivity. Watching my hubby put down a cup gives me a zap in the brain. Unbearable. And terrible brain pain movements up top - I can also feel my vagus nerve vibrate in the brain  causing indigestion and severe stomach pains.

 

Well since 4 days I have gone back to:

a) Kundalini Yoga in the afternoons - it really destresses. I feel the sweat come through the body. Thought it would increase the headaches. No, it takes all the tension away from my body.

b) CBD capsules 15 mg x 2 in the mornings and of course Omega Oil; Vitamin D and Bs

c) CBD capsule 15 mg x 1 before sleeping

d) I try  to practice mindfulness and to repeat and describe the things I am doing at that moment so to stop horrible thoughts.

 

Well, the mornings have got better. Noise sensitivity also a little better. And guess what - the severe headaches which I had for the whole day are disappearing - a feeling of slight tension is new on the sides of the brain (very new) - but only for 2-3 hrs and not so bad.

 

Must go now for my Kundalini (the DVD is just wonderful)

 

Take care and get better, Mole

November  2016 Panic Attacks, severe nausea

December  2016 short stay in hospital

                           Citalopram 20 mg 

January      2017 tapering Citalopram due to side effects: hallucinations, no sleep

                            Psychologist refuses to help me                        

January - 

August        2017 Using water method, reducing by approx. 10% 2-3 weeks 

                            At 1 mg Citalopram Withdrawal symptoms including dizzyness, neck pains, 

                            diarrohea. 

                            Supplements: Fish Oil Omega, Vitamins, Ashwagandha and now Magnesium

                             

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