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Tips for tapering off Zyprexa (olanzapine)


Altostrata

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hayduke

@Emily02I've been concerned about TD too, especially when my original prescriber said "it's not such a big deal".  Like a Hammer horror film or something, yuck.

 

I don't really have tremors, but feel more urges to stretch my fingers and hands while I taper.  A trend to more twitchy.

 

I think this, and akathisia, are probably largely induced by dopamine receptors opening up as the blockade reduces.  My hunch is it's not just about particular dopamine levels, especially once you hold and your neurology catches up, but about rate of change of dopamine levels.  I would love to taper faster but when things like this start looking like flaring up, I'd rather read the signs.

 

I found an old paper that reckoned Niacin and manganese worked in one trial.  I have both but don't take them that often. 

 

I had a blood test to check my manganese levels before getting the supplements to ensure it was safe.  It's good to do this before looking at any supplements, seeing where your body's already at with each of them.

 

I had a course of B12 booster shots which helped all round.  I had got a bit low on those.  I started taking 1500IU of Vitamin E, which I reduced to 1000IU after reading you don't want to overdo it.  I also found methyl folate helps, again you don't want to overdo it.

 

Probably the Vitamin E has been the most calming in the sense of most days seeing no tendency to tremor at all.  But still wise for me to hold when it seems helpful and let dopamine levels even out and my neurology readjust to increased amounts of it.

 

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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I'm kind of out of it right now and need to go to bed, but I just wanted to toss in my usual bit on the subject of making preparations for liquid tapering, which is: I personally don't worry about sol

Hi Lauren,   I'm a Zyprexa survivor...it can be done! Why don't you write a full intro with signature in the intro and update forum, especially if you are on other meds. I've made a lot of mistak

Just an update. I made a liquid solution with water and the orodispersible tablet. It forms a perfectly even solution so a daily taper should be accurate.

Some studies says Pyridoxine aka vitamin B6 reduces symptoms of TD. Here's a summary: https://cdn.mdedge.com/files/s3fs-public/Document/September-2018/cp01710042.pdf

 

There's some support for it as cure but more for it as at least symptom relief while taking it at 300 - 1200 mg/day. Adverse effects reported are low. However the tolerable upper limit for long term use is set by EFSA to 25 mg/day. The recommended daily intake is around 1.5 mg so those are large doses in the studies. 

 

 

A week of oxazepam 10mg with 1 day of zopiclone 7.5mg and concurrent Zyprexa totalling: 10mg 25 days , 7.5mg 18 days, 5mg 14 days, 2.5mg 11 days,  10x0mg + 4x1mg. Very bad condition reinstated: zyprexa 7.5mg zopiclone 8.5mg, 25mg Propiomazine. Next day 5mg Z. Then 6 months taper to nothing but Zyprexa and 0.0mg again. 6 days 0mg. Reinstated 0.12mg x2 days. 23 june: 0.25mg. 29 june: 0.12mg. 8th and 9th july 2020 also tried 0.375mg Melatonin. 9 july 0.16mg. Made an error of judgement in august and was forced on various drugs in hospital mainly landing on: Abilify injections + pills for a daily total of 5-15 mg (for 2½ month) + zyprexa 3 days of 10mg mostly 2.5mg but started cheating. 14 oct 2020 only zyprexa and due to cheating earlier able to go 0.31mg! 30 oct 0.21mg, 13 nov 0.14mg, 28 nov 0.10mg, 14 dec 0.07mg, 04 jan 2021 0.035mg, 25 jan 0.017mg, 4 feb 2021 0.000 mg

 

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Emily02

Hi @hayduke

TD ‘it’s not such a big deal’ OMG!

What I realised is that psychiatrists usually don’t have any empathy.

Thanks for your reply and the suggestions, I really appreciate them.

Thanks @Hopela for the excellent advice. I’ll starts supplementing with B6.

I hope you’re well.

Take care

2019 Nov-2020 January 5mg Olanzapine 

2020 January-2020 March 2,5 mg Olanzapine 

2020 March- 2020 August 5mg Olanzapine

2020 August-2020 Sept 2,5 mg Olanzapine 

2020 September-2020 November 5mg Olanzapine 

started 10% reduction 

2021 March 3,5 mg Olanzapine 

2021 April 2,5 mg Olanzapine 

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hayduke
1 hour ago, Emily02 said:

Hi @hayduke

TD ‘it’s not such a big deal’ OMG!

What I realised is that psychiatrists usually don’t have any empathy.

Thanks for your reply and the suggestions, I really appreciate them.

Thanks @Hopela for the excellent advice. I’ll starts supplementing with B6.

I hope you’re well.

Take care

 

Yeah I think he's a sadist.

 

I feel I should reiterate the SA policy of not recommending any supplements besides magnesium and omega-3.  I did my own homework and experiments with those I listed.

 

One potential snag with the Vitamin B6 @Hopela mentioned is that many members have reported it as tending to induce akathisia.  I found akathisia reduced a lot for me when I put aside the mega-B multivitamins for specific B vitamins.

 

Interestingly I generally find berocca helpful, but I was raised a drinker.

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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hayduke

I was thinking it would be helpful to get a round-up of what people's final olanzapine dosage was when they 'jumped off'.

 

I know a lot of people were up around 0.625mg (1/4 of 2.5mg tab) which I would've found a bumpy ride.  I'm at 0.30mg now and starting to think about it. 

 

Would be good to hear from everyone who has tapered (rather than gone cold turkey) off this drug about how much/little they were taking just before they stopped.

 

Cheers

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Spideygsm

I tapered for approximately 3 months. My last dose was 0.625mg which is nearly impossible to cut with any accuracy. Not fun but about 16 weeks after my last dose I started to feel much better. It wasn’t slowly feel better it was one night I slept and knew I kicked Olanzapine. 

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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3 hours ago, Spideygsm said:

I tapered for approximately 3 months. My last dose was 0.625mg which is nearly impossible to cut with any accuracy. Not fun but about 16 weeks after my last dose I started to feel much better. It wasn’t slowly feel better it was one night I slept and knew I kicked Olanzapine. 

Did you have nights where you didn’t sleep at all after tapering? Amazing that your change happened overnight

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, currently on 2.5mg Diazepam 

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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On 2/8/2013 at 2:00 PM, Altostrata said:

Since olanzapine comes in many dosages, at least initially, tapering can take place using tablets and splitting them.

I’m on 5mg of Olanzapine and I’m planning to use a compounding pharmacy to make capsules until I reach 2.5mg and then I will shave/trim my pill and weigh it until I reach dust. Does anyone know if the coated Zyprexa brand tablet can be cut? I was told by a mental health nurse and pharmacist that the Zyprexa brand can not be cut because the medication isn’t evenly distributed throughout the pill. 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, currently on 2.5mg Diazepam 

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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hayduke
30 minutes ago, Nicjk said:

I’m on 5mg of Olanzapine and I’m planning to use a compounding pharmacy to make capsules until I reach 2.5mg and then I will shave/trim my pill and weigh it until I reach dust. Does anyone know if the coated Zyprexa brand tablet can be cut? I was told by a mental health nurse and pharmacist that the Zyprexa brand can not be cut because the medication isn’t evenly distributed throughout the pill. 

 

From here:

 

'One of the biggest fears regarding tapering we encounter here at SA is that the active ingredients in a medication are not evenly distributed throughout the fillers. This leads to people thinking that if they are taking a small portion of a tablet or of the powder in a capsule that they will not be getting the “full dose” that they are expecting. This assumption is totally wrong.'

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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hayduke
4 hours ago, Spideygsm said:

I tapered for approximately 3 months. My last dose was 0.625mg which is nearly impossible to cut with any accuracy. Not fun but about 16 weeks after my last dose I started to feel much better. It wasn’t slowly feel better it was one night I slept and knew I kicked Olanzapine. 

 

Thanks, @Spideygsm.  So you felt on the hook for about 4 months after that.  Good to hear you were feeling ok before too long.  Interested to hear more people's experiences with their last dosages.

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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2 hours ago, hayduke said:

 

From here:

 

'One of the biggest fears regarding tapering we encounter here at SA is that the active ingredients in a medication are not evenly distributed throughout the fillers. This leads to people thinking that if they are taking a small portion of a tablet or of the powder in a capsule that they will not be getting the “full dose” that they are expecting. This assumption is totally wrong.'

Thank you @hayduke. That is a good read. I'm wondering though, because Zyprexa tablets are coated with a hard "shell" - how can you work out that you're actually removing say 2% of the active ingredient when you shave the tablet? 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, currently on 2.5mg Diazepam 

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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2 hours ago, hayduke said:

 

From here:

 

'One of the biggest fears regarding tapering we encounter here at SA is that the active ingredients in a medication are not evenly distributed throughout the fillers. This leads to people thinking that if they are taking a small portion of a tablet or of the powder in a capsule that they will not be getting the “full dose” that they are expecting. This assumption is totally wrong.'

Thank you @hayduke. That is a good read. I'm wondering though, because Zyprexa tablets are coated with a hard "shell" - how can you work out that you're actually removing say 2% of the active ingredient when you shave the tablet? 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, currently on 2.5mg Diazepam 

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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I have another question for everyone. I have read on this forum somewhere that when you switch from taking regular Olanzapine/Zyprexa tablets to taking liquid made by dissolving orodispersible in water, you are actually taking an extra "cut".  Why is this? Last year I switched from taking a 5mg Zyprexa tablet to dissolving an Orodispersible tablet in water and I dropped .250mg. Did I technically drop more than .250mg by switching to orodispersible in water? Perhaps you will know the answer to this @Altostrata. Thanks so much 

Mid June 2019 to mid November 2019 - Escitalopram (Lexapro) 20mg (3 week taper - psych advise) 

Reinstated 2.5mg Lexapro 3rd Jan 2020 

Increased Lexapro dose to 5mg (0.06g) 11th Jan 2020 due to continual WD symptoms, Decreased Lexapro dose to 0.05g 7th March 2020, Decreased Lexapro dose to 0.04g 7th April 2020, Decreased Lexapro dose to 0.03g 7th May 2020

Mid June 2019 to 14 Jul 2020 - Clonazepam 0.5mg 

Pericyazine (Neulactil) 20mg 24th Jun 2020 - 12th July, down to 15mg 13th July - 19th July, down to 10mg 20th July - 26th July, reinstated 15mg Pericyazine 27 July 2020 - Accidentally took 20mg for 2 nights 5 &6/8/20, CT Pericyazine 14th Sept 2020 (Psych CT and replaced with Olanzapine) 

20mg Lexapro - 16th May 2020 - 9th Sept 2020 (Psych CT and replaced with Nortriptyline) 

10mg Diazepam - 5 Aug 2020, reduced over weeks to 7mg Tuesday 29 September, updosed to 8mg 2nd October 2020, started reducing by 0.5mg every two weeks - first reduction 12th December 2020, currently on 2.5mg Diazepam 

125mg Nortriptyline - 10 Sept 2020 - Current 

5mg Olanzapine - 15th Sept 2020 - 29 Sept 2020, reduced to 2.5mg on 30 Sept 2020, back up to 5.0mg on 5th Oct 2020. Reduced to 4.750 on 9 Nov 2020, back up to 5mg Olanzapine sometime in January 2021 (current)

Supplements: Elevit (multivitamin) 

 

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Spideygsm
18 hours ago, Spideygsm said:

I tapered for approximately 3 months. My last dose was 0.625mg which is nearly impossible to cut with any accuracy. Not fun but about 16 weeks after my last dose I started to feel much better. It wasn’t slowly feel better it was one night I slept and knew I kicked Olanzapine. 

My sleep sucked before, while taking, while withdrawing, and even after kicking Olanzapine. It was really bad getting off Olanzapine. I went days with zero sleep, then 1-3 hours sleep, then zero sleep. I didn’t take Olanzapine to sleep. I took it for a mental health condition. 
 

I tried CBD while tapering. It was at about 12 weeks off Olanzapine. I think CBD and the fact I was off Olanzapine for a few months helped me feel a little better. I’ve had insomnia since a young child. I wouldn’t recommend any drugs to help sleep. For me it’s not restful or deep sleep. I got a cpap machine and it helps me. 

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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Altostrata
14 hours ago, Nicjk said:

I have another question for everyone. I have read on this forum somewhere that when you switch from taking regular Olanzapine/Zyprexa tablets to taking liquid made by dissolving orodispersible in water, you are actually taking an extra "cut".  Why is this? Last year I switched from taking a 5mg Zyprexa tablet to dissolving an Orodispersible tablet in water and I dropped .250mg. Did I technically drop more than .250mg by switching to orodispersible in water? Perhaps you will know the answer to this @Altostrata. Thanks so much 

 

I have no idea what you're talking about. You must have read this somewhere else. Have you read this topic from the beginning?

 

Switching forms of drugs may require some dosage adjustment, but nowhere do we say you're taking a reduced dosage. You may feel the liquid form is stronger or weaker. 

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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hayduke
17 hours ago, Spideygsm said:

My sleep sucked before, while taking, while withdrawing, and even after kicking Olanzapine. It was really bad getting off Olanzapine. I went days with zero sleep, then 1-3 hours sleep, then zero sleep. I didn’t take Olanzapine to sleep. I took it for a mental health condition. 
 

I tried CBD while tapering. It was at about 12 weeks off Olanzapine. I think CBD and the fact I was off Olanzapine for a few months helped me feel a little better. I’ve had insomnia since a young child. I wouldn’t recommend any drugs to help sleep. For me it’s not restful or deep sleep. I got a cpap machine and it helps me. 

 

As I recall, you did a much faster taper than 10%/mo on medical advice?

 

I've been tempted by CBD earlier in the taper, but it's so costly over here.  I don't also mind my body having one less thing in the mix as I go, but I can see how it would've helped you.

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Spideygsm
4 hours ago, hayduke said:

 

As I recall, you did a much faster taper than 10%/mo on medical advice?

 

I've been tempted by CBD earlier in the taper, but it's so costly over here.  I don't also mind my body having one less thing in the mix as I go, but I can see how it would've helped you.

Tapered from November  2017-March 2018 from 30mg. This was under a doctors supervision and for severe side effects. I wouldn’t recommend anybody ever go Cold Turkey. I actually went slower than my Doctor recommend. Do what’s comfortable for you. For me it sucked the entire time and 4 months after. I wouldn’t recommend CBD only because I tried it near the end of my withdrawals and I think it was more of a placebo effect. 

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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hayduke
On 5/25/2021 at 3:54 AM, Spideygsm said:

Tapered from November  2017-March 2018 from 30mg. This was under a doctors supervision and for severe side effects. I wouldn’t recommend anybody ever go Cold Turkey. I actually went slower than my Doctor recommend. Do what’s comfortable for you. For me it sucked the entire time and 4 months after. I wouldn’t recommend CBD only because I tried it near the end of my withdrawals and I think it was more of a placebo effect. 

 

That's a crash taper for sure.  I would've been wrung out by that too, I'm actually having trouble thinking of a setting where I could've stood that. 

 

But you've come through which is really good.

 

I don't think I'm aware of anyone who's successfully CT'd olanzapine and got off the hook that way.

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Spideygsm

I developed dangerous side effects including high liver panels, pre diabetic, and Tardive Dyskinesia. Knowing that made it important and a reason to stop. 

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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hayduke
On 5/29/2021 at 9:09 AM, Spideygsm said:

I developed dangerous side effects including high liver panels, pre diabetic, and Tardive Dyskinesia. Knowing that made it important and a reason to stop. 

 

Had those, reset pre diabetes twice by fasting.  What was the deal with your TD?  I've been getting twitchier hands and hope they will settle down as my dopamine levels even out.

 

Did the crash taper make your TD symptoms worse, and did they improve over time after that?

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Spideygsm

My head twitched uncontrollably. The taper did not make things worse. The symptoms did reduce quite a bit after about a year but I still get occasion twitching but not to the extent that it interferes or bothers me. 

December 2017: Zyprexa (30mg)  Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

Feb 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg)

March 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Valium (10mg) Ambien (10mg) Lamicital (450mg)

April 2018: Gabapentin (1800mg)  Wellbutrin (450mg) Lamicital (450mg) (Dropped Ambien, Valium no help)

May 2018:  Gabapentin (1800mg)  Wellbutrin (37.5mg)  Lamicital (450mg) Trazodone (150mg) CBD (20mg)

Present: Gabapentin (600mg)  Prazosin (10mg)  Lamicital  Trazodone (125mg)

1969 - Present: 80 Electro Convulsive Treatments, Medication changes (Too many drugs to list prior to Dec 2017) Klonipin/Xanax CT 2003

Wellbutrin Taper: Started approx  Apr 2018 450mg, 300mg, 225mg, 150mg, 112.5mg, 75mg, 37.5mg Held each dose approx 1 week per Doctor, June 5 2018 OFF WELLBUTRIN

Zyprexa Taper: Nov 2017 30mg, Dec 1 2017 20mg, Dec 11 2017 15mg, Dec 22 2017 10mg, Jan 3 2018 7.5mg, Jan 14 2018 5mg, Jan 25 2018 3.75mg, Feb 6 2018 2.5mg, Feb 16 2018, 1.25mg, Feb 25 2018 0.625mg, March 4 2018 OFF Zyprexa!!!!

Trazodone Taper: April 2018-150mg, May 25 2018-100mg, June 1 2018-50mg,  Bump June 2 2018-125mg HOLD

 

 

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hayduke

Sorry you've had to suffer that @Spideygsm.  I'm glad to hear it's much improved.

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Desiderata

Hi Hayduke, I am wanting to taper off 2.5 mg olanzapine. I have recently gotten a prescription of 2.25 mg custom capsules from a local compounding pharmacy. I haven’t seen where anyone else has used this method and I’m wondering why. It seems like a practical way to taper but my anxiety is causing me to think I’m missing something. I would very much appreciate any input and / or assurances that this is a safe and effective plan. Thank you very much! 

Depakote 1000 mg.     1997-present.   
Olanzapine 2.5 mg.      2012-present

Attempted taper of olanzapine by alternating 2.5 mg with 1.85 mg April, May 2021 

Reinstated 2:5 mg June 2021

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Altostrata

@Desiderata, please see the first post in this topic.

 

Having olanzapine compounded into custom capsules is a reasonable way to taper. People probably don't use it as often because of the expense.

 

 

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Desiderata

Thank you Altostrata! Much appreciated! I was also able to make and print Brass Monkey sliding scale taper and think I will go that route. As you can probably tell, I am very nervous about all of this! Thanks for being there!

Depakote 1000 mg.     1997-present.   
Olanzapine 2.5 mg.      2012-present

Attempted taper of olanzapine by alternating 2.5 mg with 1.85 mg April, May 2021 

Reinstated 2:5 mg June 2021

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hdmiTable

Hi all,

 

Can someone please help me understand this?

 

Quote

Olanzapine is sparingly soluble in aqueous buffers. For maximum solubility in aqueous buffers, olanzapine should first
be dissolved in DMSO and then diluted with the aqueous buffer of choice. Olanzapine has a solubility of approximately
0.5 mg/ml in a 1:1 solution of DMSO:PBS (pH 7.2) using this method. We do not recommend storing the aqueous
solution for more than one day.

 

Does this mean that if I want to dissolve a 7.5mg tablet, I would need 7.5ml DMSO and 7.5ml PBS? Would I need to first dissolve the tablet in 7.5ml DMSO and then add the PBS?

 

Thanks in advance

 

 

2021 Jan - Haldol 3mg

2021 Feb - Aripriprazol 10mg

2021 Mar - Aripriprazol 10mg

2021 Apr - Aripriprazol 10mg

2021 May - Zyprexa 7.5mg

2021 Jun - Zyprexa 7.5mg

2021 Jul 1 - Zyprexa 7.2mg | Jul 6 - 6.9mg | Jul 25 - 6.8mg | Jul 31 - 5.5mg

 

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brassmonkey

"Olanzapine has a solubility of approximately
0.5 mg/ml in a 1:1 solution of DMSO:PBS (pH 7.2) using this method."

 

A 1:1 solution of DMSO:PBS means that the liquid is 1/2 DMSO and 1/2 PBS

 

This statement says you can dissolve 0.5mg of Olanzapine in 1mL of a liquid that is 1/2 DMSO and 1/2 PBS. 

 

The tablets you are using contains 7.5mg of Olanzapine so you would need 3.5mL of DSMO mixed with 3.5mL of PBS to dissolve all of the Olanzapine. This will give you a solution containing 1mg of Olanzapine for every 1mL of liquid.

 

Mix the DSMO and the PBS then add one crushed tablet. Shake it up and let it sit in a cool dark place for several hours. Shake it up occasionally while it sits. According to the statement above the new liquid is only good for one day, so it needs to be used right away.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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hdmiTable

Many thanks @brassmonkey for making it clear.

 

I couldn't get my hands on PBS so will try with physiological saline solution instead, if it doesn't work will use pure DMSO

 

Thanks again will try this tomorrow.

 

 

2021 Jan - Haldol 3mg

2021 Feb - Aripriprazol 10mg

2021 Mar - Aripriprazol 10mg

2021 Apr - Aripriprazol 10mg

2021 May - Zyprexa 7.5mg

2021 Jun - Zyprexa 7.5mg

2021 Jul 1 - Zyprexa 7.2mg | Jul 6 - 6.9mg | Jul 25 - 6.8mg | Jul 31 - 5.5mg

 

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brassmonkey

You could also use homemade 9% saline. All the buffering agents do it stabilize the pH (acidity) of the saline. This could be important for an injectable solution, but for one you drink it shouldn't make much difference.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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hdmiTable

Thank you @brassmonkey

 

Earlier you said that mixing 3.5ml of the saline solution and 3.5ml DMSO would dissolve a 7.5mg tablet yielding a solution of 1mg / 1ml Olanzapine. Did you mean 3.75?

2021 Jan - Haldol 3mg

2021 Feb - Aripriprazol 10mg

2021 Mar - Aripriprazol 10mg

2021 Apr - Aripriprazol 10mg

2021 May - Zyprexa 7.5mg

2021 Jun - Zyprexa 7.5mg

2021 Jul 1 - Zyprexa 7.2mg | Jul 6 - 6.9mg | Jul 25 - 6.8mg | Jul 31 - 5.5mg

 

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brassmonkey

Good catch. The number gods have been unhappy with me lately. Yes, 3.75.

20 years on Paxil starting at 20mg and working up to 40mg. Sept 2011 started 10% every 6 weeks taper (2.5% every week for 4 weeks then hold for 2 additional weeks), currently at 7.9mg. Oct 2011 CTed 15oz vodka a night, to only drinking 2 beers most nights, totally sober Feb 2013.

Since I wrote this I have continued to decrease my dose by 10% every 6 weeks (2.5% every week for 4 weeks and then hold for an additional 2 weeks). I added in an extra 6 week hold when I hit 10mg to let things settle out even more. When I hit 3mgpw it became hard to split the drop into 4 parts so I switched to dropping 1mgpw (pill weight) every week for 3 weeks and then holding for another 3 weeks.  The 3 + 3 schedule turned out to be too harsh so I cut back to dropping 1mgpw every 4 weeks which is working better.

Current dose 0.000mg 04-15-2017

 

"It's also important not to become angry, no matter how difficult life is, because you can loose all hope if you can't laugh at yourself and at life in general."  Stephen Hawking

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Mahadeva

Hi, im tappering of 5mg of olanzapine with micro taper water solution method.

 

My question is, the white particles that suspends trough the liquid like tiny "dust", that is something else used for capsules or have the olanzapine active principle on it?

 

I'm taking 2ml's of 20ml's water solution, sometimes that white particles come in a little more amount in the syringer and others a little less, and i try to match them some times.

 

If the drug active principle is evenly distributed in on the liquid i would just need to take the same amount in ml's everytime not worring about the white particles amount, but if not, i cant mess with the particles amount.

 

Someone can clarify that?

Being under several meds, most antipsychotics, benzos in small periods as mood regulators. (reason: the usage of cannabis induced me severe psychosis 7 times in my life)

12 year under meds, Haldol, Risperidone (2 years), Seroquel (2 years), Aripiprazole (6-7 years) as main meds.

Clonazepam, depakene ,lithium, alprazolam in short periods, at hospitalizations (6) was under several meds at time.

2019 went cold turkey on aripiprazole after years taking it, 4 months of intense suffering, recovered after month 4-5, was doing pretty well till going back on the use of cannabis and got psychotic again

november 2019 - april 2020 spent on drug clinic, got out of it under the use of Lithium (1200mg) Depakene (700mg) Clonazapam (2mg) Olanzapine (5mg)

Between May-July 2020 i tapered of completely Clonazepam and Depakene not much problem from where i was already standing

19/10 2020 started tapering lithium - 300mg morning 600mg night

26/10 2020 lithium 300mg morning 300 mg night

30/11 2020 lithium 150mg morning 300 mg night

*Planning to start liquid 10% taper with Olanzapine in 2021 few months after ending lithium tapper.

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hayduke
1 minute ago, Mahadeva said:

Hi, im tappering of 5mg of olanzapine with micro taper water solution method.

 

My question is, the white particles that suspends trough the liquid like tiny "dust", that is something else used for capsules or have the olanzapine active principle on it?

 

I'm taking 2ml's of 20ml's water solution, sometimes that white particles come in a little more amount in the syringer and others a little less, and i try to match them some times.

 

If the drug active principle is evenly distributed in on the liquid i would just need to take the same amount in ml's everytime not worring about the white particles amount, but if not, i cant mess with the particles amount.

 

Someone can clarify that?

 

Hi Mahadeva,

 

Typically the flakes are filler, and you needn't worry as long as the mixture is well shaken/stirred.  I also find it helps to let the tablet disintegrate fully, for up to half an hour with some generics I've had.

 

I'm in the habit of agitating with syringe or pipette (i.e draw in some suspension and push out a few times to mix it better) just before drawing out your dose. 

 

You should find you can get a very consistent dosage this way.

 

Cheers

My taper visualised as a graph   |   My intro thread

I am not a health professional - your actions are your own

 

Backdrop:  10mg olanzapine 2003-06.  3mg risperidone 2006-2014.  Abortive x-taper to aripiprazole Dec 2014, back to 10mg olanzapine after 3 weeks.

2015:  10 -> 7 1/2 -> 6 2/3 -> 5mg olanzapine using pill cutter

2018:  Finer taper liquid suspension 5mg to 2.5 Mar-Aug and hold

2019: Jan 2.5 | Eostre EMDR@2.1mg | Jul 1.625 | Oct 1.3

2020: Jan 1.214 | Apr 0.88 | July 0.69 | Oct 0.525

2021: Jan EMDR@0.44 | Apr 0.38 | Jul 0.26 | Aug 0.24

"Ask not what you can do for your country, but what your country did to you"  -- KMFDM

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Mahadeva
13 minutes ago, hayduke said:

 

Hi Mahadeva,

 

Typically the flakes are filler, and you needn't worry as long as the mixture is well shaken/stirred.  I also find it helps to let the tablet disintegrate fully, for up to half an hour with some generics I've had.

 

I'm in the habit of agitating with syringe or pipette (i.e draw in some suspension and push out a few times to mix it better) just before drawing out your dose. 

 

You should find you can get a very consistent dosage this way.

 

Cheers

alright good, im doing like that, i let half hour, than i mix before drawing with the syringer and move the syringer slowly trought the solution to draw 2 ml

 

thank you!

Being under several meds, most antipsychotics, benzos in small periods as mood regulators. (reason: the usage of cannabis induced me severe psychosis 7 times in my life)

12 year under meds, Haldol, Risperidone (2 years), Seroquel (2 years), Aripiprazole (6-7 years) as main meds.

Clonazepam, depakene ,lithium, alprazolam in short periods, at hospitalizations (6) was under several meds at time.

2019 went cold turkey on aripiprazole after years taking it, 4 months of intense suffering, recovered after month 4-5, was doing pretty well till going back on the use of cannabis and got psychotic again

november 2019 - april 2020 spent on drug clinic, got out of it under the use of Lithium (1200mg) Depakene (700mg) Clonazapam (2mg) Olanzapine (5mg)

Between May-July 2020 i tapered of completely Clonazepam and Depakene not much problem from where i was already standing

19/10 2020 started tapering lithium - 300mg morning 600mg night

26/10 2020 lithium 300mg morning 300 mg night

30/11 2020 lithium 150mg morning 300 mg night

*Planning to start liquid 10% taper with Olanzapine in 2021 few months after ending lithium tapper.

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