aka Aropax, Paroxat, Deroxat, Rexetin, Sereupin, Seroxat, Xetanor Paxil and Effexor have long led the list of antidepressants notorious for difficult withdrawal, the others being Zoloft and Luvox. (But this may be because Paxil and Effexor have been very widely prescribed for a long time; Lexapro and Cymbalta are certainly also very difficult to taper.) From the July 2011 Medication Guide from GlaxoSmithKline here (PDF) http://us.gsk.com/products/assets/us_paxil.pdf     Fr