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Differences in TCAs vs SSRIs in regards to withdrawal?


dunerbug
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I'm wondering if there is much of a difference in protracted withdrawal symptoms.

 

I don't see as many people struggle getting off tricylics on forums like this.

Started Fluoxetine Jan. 2010

Tried to go off of it in Sept. 2010

Weaned too fast and was back on it by Nov. 2010

Didn't work as good the second time around.

Started to wean again in Nov. 2011 and was off for good by April? 2012

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Part of the reason I was asking is because I'm still having some pretty bad bladder issues. I fully wet myself at least once a week. Please don't tell me to do keagals (sp?) Already trying that.

This has been a pretty consistent symptom since coming off prozac. Last week I soiled each of our cars. I'm 33 years old. I seems to get worse right before and sometimes during my period.

 

I was researching on the net and saw that they give Imipramine to those with bladder issues. I'm very tempted. My depression and anxiety are still debilitating. As well as a host of other symptoms, I don't seem to be getting better. There is also Clomipramine that helps with OCD as well as bladder issues.

 

I have a neurologist appt. on the 24th and I know he is going to want to put me on something. I will fight it until I feel I've run out of answers. 

 

I'm sorry if it seems I'm fishing for support for getting back on meds. Thought of being back on makes me very upset. I don't want to at all....but I want relief so very bad.

Started Fluoxetine Jan. 2010

Tried to go off of it in Sept. 2010

Weaned too fast and was back on it by Nov. 2010

Didn't work as good the second time around.

Started to wean again in Nov. 2011 and was off for good by April? 2012

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Oh, sorry! Not fun....on top of the other not fun. We just want what is best for you! I think we maybe see fewer TCA's here because they aren't used as much as the newer drugs for psych issues. I hope you end up with a great doc!

1st round Prozac 1989/90, clear depression symptoms. 2nd round Prozac started 1999 when admitted to dr. I was tired. Prozac pooped out, switch to Cymbalta 3/2006. Diagnosed with bipolar disorder due to mania 6/2006--then I was taken abruptly off Cymbalta and didn't know I had SSRI withdrawal. Lots of meds for my intractable "bipolar" symptoms.

Zyprexa started about 9/06, mostly 5mg. Tapered 4/12 through12/29/12

Wellbutrin. XL 300 mg started 1/07, tapered 1/18/13 through 7/8/13

Oxazepam mostly continuously since 6/06, 30mg since 12/12, tapered 1.17.14 through 8.26.15

11/06 Lithium 600mg twice daily, 2.2.14 400mg TID DIY liquid, 2.12.14 1150mg, 3.2.14 1100mg, 3.18.14 1075mg, 4/14 updose to 1100mg, 6.1.14 900 mg capsules 7.8.14 810mg, 8.17.14 725mg, 8.24.24 700mg...10.22.14 487.5mg, 3.9.15 475mg, 4.1.15 462.5mg 4.21.15 450mg 8.11.15 375mg, 11.28.15 362.5mg, back to 375mg four days later, 3.4.16 updose to 475 (too much going on to risk trouble)

9/4/13 Toprol-XL 25mg daily for sudden hypertension, tapered 11.12.13 through 5.3.14, last 10 days or so switched to atenolol

7.4.14 Started Walsh Protocol

56 years old

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I'm hoping too! I'm nervous though...

 

I am lucky to get in to see this neurologist so soon. The other one couldn't get me in until Jan.

 

Part of what makes me nervous is that this guy is on the board of psychiatry. 

I'm bringing my husband with me to help back me up. I don't want to take something out of desperation. 

Started Fluoxetine Jan. 2010

Tried to go off of it in Sept. 2010

Weaned too fast and was back on it by Nov. 2010

Didn't work as good the second time around.

Started to wean again in Nov. 2011 and was off for good by April? 2012

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That is a good point about fewer of them being prescribed.

Started Fluoxetine Jan. 2010

Tried to go off of it in Sept. 2010

Weaned too fast and was back on it by Nov. 2010

Didn't work as good the second time around.

Started to wean again in Nov. 2011 and was off for good by April? 2012

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At your age I'd be pretty sure you are having muscle spasm, not muscle laxity. So Kagals (or whatever) won't help. Do you take magnesium and fish oil? If I remember right, you're into supplements? Have you added or taken anything away that could do this? Does it feel like the bladder compressing or like the sphincter opening? I am just fishing for ideas to help you with Dr. Google. :)

1st round Prozac 1989/90, clear depression symptoms. 2nd round Prozac started 1999 when admitted to dr. I was tired. Prozac pooped out, switch to Cymbalta 3/2006. Diagnosed with bipolar disorder due to mania 6/2006--then I was taken abruptly off Cymbalta and didn't know I had SSRI withdrawal. Lots of meds for my intractable "bipolar" symptoms.

Zyprexa started about 9/06, mostly 5mg. Tapered 4/12 through12/29/12

Wellbutrin. XL 300 mg started 1/07, tapered 1/18/13 through 7/8/13

Oxazepam mostly continuously since 6/06, 30mg since 12/12, tapered 1.17.14 through 8.26.15

11/06 Lithium 600mg twice daily, 2.2.14 400mg TID DIY liquid, 2.12.14 1150mg, 3.2.14 1100mg, 3.18.14 1075mg, 4/14 updose to 1100mg, 6.1.14 900 mg capsules 7.8.14 810mg, 8.17.14 725mg, 8.24.24 700mg...10.22.14 487.5mg, 3.9.15 475mg, 4.1.15 462.5mg 4.21.15 450mg 8.11.15 375mg, 11.28.15 362.5mg, back to 375mg four days later, 3.4.16 updose to 475 (too much going on to risk trouble)

9/4/13 Toprol-XL 25mg daily for sudden hypertension, tapered 11.12.13 through 5.3.14, last 10 days or so switched to atenolol

7.4.14 Started Walsh Protocol

56 years old

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I was, at one point, taking a ton of supps. I cut them all because of sensitivity issues. I'm gun shy now. I did take a very weak multi and some d3 today and because my anxiety is bad I was going to take some mag . But I wanted to see how d3 hits me first.

 

I'll have to think on the bladder question. The only way I can describe it is....."hmmmm, I think I have to pee" and this goes to "Oh **** I peed myself" very quickly. For a time I was getting up to pee during the night....sometimes more than once. 

 

It's weird too, that it changes in severity. Sometimes it's not as dramatic.  I notice that when I'm feeling bad in general (physically and mentally) it worsens.

 

One time while driving, I went from 0-pee super quick but tried to hold it. I ended up with terrible pain in my kidney. Once I let go and peed it got better....granted, I peed all over my car.

Started Fluoxetine Jan. 2010

Tried to go off of it in Sept. 2010

Weaned too fast and was back on it by Nov. 2010

Didn't work as good the second time around.

Started to wean again in Nov. 2011 and was off for good by April? 2012

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One of the drawbacks of the tricyclics was withdrawal syndrome, which is why at first the SSRIs were promoted as having no withdrawal problems.

 

Also, the tricyclics are still serotonergics. If your system has been sensitized by withdrawal or adverse reactions, you may get unanticipated reactions to TCAs, too.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Thanks Alto-

 

I guess I'm hoping there is a way out of this mess. I want to be fixed.

 

Today has been horrific. Other than being on my cycle, I took some supps yesterday and today. All it was was a very light multi vit and some d3. (2000 iu)

I feel like checking myself into the hospital. 

 

It would be extremely naive of me to think that I could transition onto another med when I can't even take vit d without feeling like death.

 

I feel like I'm getting a little too close to the end of my rope.

Started Fluoxetine Jan. 2010

Tried to go off of it in Sept. 2010

Weaned too fast and was back on it by Nov. 2010

Didn't work as good the second time around.

Started to wean again in Nov. 2011 and was off for good by April? 2012

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Have you thought about the Lamictal option? The end of the rope is not a good place to be!

1st round Prozac 1989/90, clear depression symptoms. 2nd round Prozac started 1999 when admitted to dr. I was tired. Prozac pooped out, switch to Cymbalta 3/2006. Diagnosed with bipolar disorder due to mania 6/2006--then I was taken abruptly off Cymbalta and didn't know I had SSRI withdrawal. Lots of meds for my intractable "bipolar" symptoms.

Zyprexa started about 9/06, mostly 5mg. Tapered 4/12 through12/29/12

Wellbutrin. XL 300 mg started 1/07, tapered 1/18/13 through 7/8/13

Oxazepam mostly continuously since 6/06, 30mg since 12/12, tapered 1.17.14 through 8.26.15

11/06 Lithium 600mg twice daily, 2.2.14 400mg TID DIY liquid, 2.12.14 1150mg, 3.2.14 1100mg, 3.18.14 1075mg, 4/14 updose to 1100mg, 6.1.14 900 mg capsules 7.8.14 810mg, 8.17.14 725mg, 8.24.24 700mg...10.22.14 487.5mg, 3.9.15 475mg, 4.1.15 462.5mg 4.21.15 450mg 8.11.15 375mg, 11.28.15 362.5mg, back to 375mg four days later, 3.4.16 updose to 475 (too much going on to risk trouble)

9/4/13 Toprol-XL 25mg daily for sudden hypertension, tapered 11.12.13 through 5.3.14, last 10 days or so switched to atenolol

7.4.14 Started Walsh Protocol

56 years old

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I am in the same place as Dunerbug because I think I may have to go back onto a med but don't know what kind to ask for.  Why do you ask about the Lamictal option. How is lamictal better or different or safer?

2002? zoloft.  Start of synthroid unknown.

2002? switched to paxil  - Developed restless leg syndrome. stopped all caffeine which helped for many years.

2003? switched to effexor XL 75 mg. May 2012 began taper

July 2012 stopped all effexor . Usual WD symptoms, lost excess weight, had more energy. RLS stopped immediately!

Sept 2012 depression off and on, increasing. Tried tryptophan and acupuncture

Dec 2012 severe anxiety began

February 2013 used magnolia bark for anxiety - helped but developed central sleep apnea, so I stopped it

by April 2013- stopped tryptophan, using saffron herb successfully and started HRT

June 2013 doctor noticed bradycardia. I tried very small dose cytomel sev days for hypothyroidism but seemed to strain my heart.

July 2013 stopped saffron due to slow heart and palpitations - did not help.

July 2013 Increased synthroid from 50mg to 75mg. depression and anxiety improved. Heart problems continue.

September & October 2013 - 2 month course of antibiotic for possbile lyme disease - mood and anxiety improved further.  Heart pvc's flair up at times. 

 

 

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I'm talking about micro-dosing with it as a support during withdrawal, not actual treatment. You can search the forums

under lamotrigine. And it's certainly not guaranteed to work.

1st round Prozac 1989/90, clear depression symptoms. 2nd round Prozac started 1999 when admitted to dr. I was tired. Prozac pooped out, switch to Cymbalta 3/2006. Diagnosed with bipolar disorder due to mania 6/2006--then I was taken abruptly off Cymbalta and didn't know I had SSRI withdrawal. Lots of meds for my intractable "bipolar" symptoms.

Zyprexa started about 9/06, mostly 5mg. Tapered 4/12 through12/29/12

Wellbutrin. XL 300 mg started 1/07, tapered 1/18/13 through 7/8/13

Oxazepam mostly continuously since 6/06, 30mg since 12/12, tapered 1.17.14 through 8.26.15

11/06 Lithium 600mg twice daily, 2.2.14 400mg TID DIY liquid, 2.12.14 1150mg, 3.2.14 1100mg, 3.18.14 1075mg, 4/14 updose to 1100mg, 6.1.14 900 mg capsules 7.8.14 810mg, 8.17.14 725mg, 8.24.24 700mg...10.22.14 487.5mg, 3.9.15 475mg, 4.1.15 462.5mg 4.21.15 450mg 8.11.15 375mg, 11.28.15 362.5mg, back to 375mg four days later, 3.4.16 updose to 475 (too much going on to risk trouble)

9/4/13 Toprol-XL 25mg daily for sudden hypertension, tapered 11.12.13 through 5.3.14, last 10 days or so switched to atenolol

7.4.14 Started Walsh Protocol

56 years old

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2000 iu vitamin D is a hefty dose. You may wish to try a lower dose.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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I don't think I'll be taking anymore. I'm too scared. I was in bed from like 2 pm on. Couldn't even eat dinner. Today I feel so wiped and achy and sad.

 

I'm worn down. I want to scream out at the top of my lungs "HELP ME!!!" But there's no help.......

Started Fluoxetine Jan. 2010

Tried to go off of it in Sept. 2010

Weaned too fast and was back on it by Nov. 2010

Didn't work as good the second time around.

Started to wean again in Nov. 2011 and was off for good by April? 2012

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