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Kendall7858: Tapering from a drug cocktail


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I am new to the discussion.  I am on 400 mg Seroquel XR, .25 mg klonopin, 30 mg temazepam, and 200 mg doxepin. I think cocktails are destructive and can lead to suicide.  I have been tapering the klonopin.  My concern is with the seroquel xr.  If I want to taper the seroquel at some point, how can I procede.  I can't just cut the xr tablet.  How can I deal with this. I go into withdrawal symptoms when I come of the seroquel.  My life is ruined!



Extensive history of multiple psychiatric cocktails

400mg Seroquel XR, 200 mg doxepin, 30 mg Temazepam, 1 mg klonopin

tapered klonopin and temazepam 6 months ago

switched from seroquel to 15 mg zyprexa while cotinuing doxepin

switched back to seroquel with doxepin

dropped doxepin cold turkey while inpatient

placed on 1350 lithium, 80 mg Latuda, 60 mg propanalol, 1mg klonopin, 100 mg seroquel inpatient again

dropped lithium and latuda

tapering klonopin for a month

very sick and in horrendous pain, hard to know what to do, many opinions not much success,  horrendous insomnia.

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  • Moderator Emeritus

It's difficult to offer any ideas without knowing more about your background, so when you have a chance, please put your drug history in your signature like this:


How To Add Your Drug History To Your Signature


It's generally best to first get off the antipsychotic, then the antidepressant, and leave the benzos for last as they can help a person get through some of the unpleasant effects of withdrawing from the other two. You might want to stop tapering the Klonopin for now. Do you know why your doctor prescribed two benzodiazepines? Klonopin and temazepam are the same type of drug.


Your life isn't ruined and telling yourself that it is, isn't at helpful at all.  It may take a long while to taper off the drugs you're on, but it can be done with a minimum of discomfort.


Welcome to the forum, Kendall. You'll find lots of good information and friendly support here.

Psychotropic drug history: Pristiq 50 mg. (mid-September 2010 through February 2011), Remeron (mid-September 2010 through January 2011), Lexapro 10 mg. (mid-February 2011 through mid-December 2011), Lorazepam (Ativan) 1 mg. as needed mid-September 2010 through early March 2012

"Never attribute to malice that which is adequately explained by stupidity." -Hanlon's Razor

Introduction: http://survivingantidepressants.org/index.php?/topic/1588-introducing-jemima/


Success Story: http://survivingantidepressants.org/index.php?/topic/6263-success-jemima-survives-lexapro-and-dr-dickhead-too/

Please note that I am not a medical professional and my advice is based on personal experience, reading, and anecdotal information posted by other sufferers.


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  • Administrator

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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  • 2 years later...

Kendall how are you doing these days?

Are you able to do an update?

Thought for the day: Lets stand up, and let’s speak out , together. G Olsen

We have until the 14th. Feb 2018. 

URGENT REQUEST Please consider submitting  for the petition on Prescribed Drug Dependence and Withdrawal currently awaiting its third consideration at the Scottish Parliament. You don't even have to be from Scotland. By clicking on the link below you can read some of the previous submissions but be warned many of them are quite harrowing.


Please tell them about your problems taking and withdrawing from antidepressants and/or benzos.

Send by email to petitions@parliament.scot and quote PE01651 in the subject heading. Keep to a maximum of 3 sides of A4 and you can't name for legal reasons any doctor you have consulted. Tell them if you wish to remain anonymous. We need the numbers to help convince the committee members we are not isolated cases. You have until mid February. Thank you

Recovering paxil addict

None of the published articles shed light on what ssri's ... actually do or what their hazards might be. Healy 2013. 

This is so true, with anything you get on these drugs, dependance, tapering, withdrawal symptoms, side effects, just silent. And if there is something mentioned then their is a serious disconnect between what is said and reality! 

  "Every time I read of a multi-person shooting, I always presume that person had just started a SSRI or had just stopped."  Dr Mosher. Me too! 

Over two decades later, the number of antidepressant prescriptions a year is slightly more than the number of people in the Western world. Most (nine out of 10) prescriptions are for patients who faced difficulties on stopping, equating to about a tenth of the population. These patients are often advised to continue treatment because their difficulties indicate they need ongoing treatment, just as a person with diabetes needs insulin. Healy 2015

I believe the ssri era will soon stand as one of the most shameful in the history of medicine. Healy 2015

Let people help people ... in a natural, kind, non-addictive (and non-big pharma) way. J Broadley 2017



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