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Anbu, 2006 Fluoxetine Withdrawal Syndrome in the Newborn.


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Indian Pediatr. 2006 Jan;43(1):66-9.
Fluoxetine withdrawal syndrome in the newborn.
Anbu AT, Theodore A.

Abstract and free full text at http://www.ncbi.nlm.nih.gov/pubmed/16465011

A term baby was admitted to our neonatal unit with jitteriness, hypertonia, sneezing and fever. Her mother was on 20 mg of fluoxetine throughout her pregnancy. These symptoms which were possibly due to fluoxetine withdrawal lasted only for a short while. We attempt to look at the reported prevalence of this condition in the literature.

From the paper:
"The US Food and Drug administration (FDA) Adverse Event Reporting System(9) recorded 57 instances of SSRI-related neonatal withdrawal syndrome by November 2001."
"The most commonly reported neonatal symptoms include agitation,irritability, impending seizures, hypertonia or hypotonia, hyperreflexia, drowsiness, jitteriness,feeding problems, persistent crying,tachypnoea, temperature instability, acrocyanosis and tremors. In addition fluoxetine toxicity has been observed as scattered petechiae over the face and trunk along with cephalhaematoma(5), marked motor
automatism and skin manifestations(6). It has also been associated with colic(3), lipomeningocele(4), and cardiac arrhythmia(7)."
A., Anbu & A. Thoedore (2006). Fluoxetine Withdrawal Syndrome in the Newborn. Indian Pediatrics, 43, 66-69 : Can be found online at  http://medind.nic.in/ibv/t06/i1/ibvt06i1p66.pdf

Edited by Altostrata
put in Journals format

1988-2012: Prozac @ 60mg to treat an eating disorder. Several unsuccessful attempts to discontinue.Fall 2012: Failed attempt to discontinue then -> 40mg Prozac and added 150mg Wellbutrin. Late summer 2013:Began slower Prozac taper.Spring 2014:Got to 10mg Prozac, 75mg of Wellbutrin -April 2014: 9mg Prozac & 37.5mg Wellbutrin 2x/day -> 9mg Prozac & 25 mg Wellbutrin 2x/day->9mg Prozac 1x/day & ~8mg Wellbutrin 2x/day -> 8.1mg Prozac, 0 WellbutrinSept '14: 8.1mg Prozac -> crashed hardOct '14: 10mg ProzacNov '14: 20mg -> 30mgDec '14: 30mg, Feb 10: 27mg. Mar 7: 25mg Mar 21, 2015: 20mg. May 21, 2016: 20mg and holding strong. Taper restarted April 2021 to 18mg, July 2021 to 16mg, currently 15mg. 


My experience: http://rxisk.org/antidepressant-withdrawal-a-prozac-story/

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  • 2 weeks later...

There are many stories like this for many ssri and snri drugs. Sad. 

Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 


There is a crack in everything ..That's how the light gets in :)

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