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Phandy: Taper Quetiapine 450mg Question


phandy

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Hi, I have already become free of Mirtazapine (45mg), Venaflaxine (75mg), and Lithium (1200mg). I have Quetiapine (450mg) and Lorazepam (1mg) left to taper.

 

My aim is to begin tapering Quetiapine on 1st December. I have read the articles and posts on this subject as a 'lurker' for some time. If I follow the 10% rule, I should start decreasing my dose of Quetiapine by 45mg a month. My question: should I just drop 45mg on the 1st of the month and remain on that dose for 1 month? Or, should I decrease by 12.5 per week for the first month? So, by the end of the first month I would have reduced by cc 50mg?

 

I tried to start decreasing quetiapine about six months ago. I initially dropped the dose by 50mg in around 2/3 weeks - over confident and little research. This threw me into a complete state of anxiety/ panic for about 8 weeks so I stopped my taper and returned to my previous dose of 450mg. That was 6 month's ago and now it is time to taper again.

 

Any advice appreciated.

 

James

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Hi James

Just wondered how you got on coming off Mirt and Lithium, as these are 2 drugs which I will eventually start to taper. Do I get the impression that Lithium is quite straight forward.? I only say this because in the past 6 years I have experimented with the dose to no ill effect. (im now on a sub-therapeutic dose of about 600mg) Its meant to be augmenting the effects of the other 2 ADs.(The Americans on this site don't seem to have experience of this function) MIRT  has the effect off sleep problems I think? How long did all that take?

All the best with the rest of your tapers.

 

Simon

. Been on some kind of meds since 1982,mainly on and off things like imipramine.,2000 on75mg venlafaxine til it bottomed out, then 150, also no good. about 7 years. Almost ct from it and put on cocktail of  Cit, Mirt and Lithium. Remained there for 7 years.

Tapered Citalopram in June2014 and was off in 6 weeks. Mood slumped about 6 weeks later. Found this site sept 5th and got some idea why this happens.18th Sept stopped lorezepam and due to misunderstanding with GP was without it for 36 hours which caused a crisis.

from 19thsept 18mg diazepam to replace lorezepam(possible addiction) 24th sept 12 mg diaz per day. 29th sept 10mg diaz per day and tapering at 1-2mg per week. At 5mg will slow down taper. At same time increase of mirtazapine to 45mg per day.

Taking fish oil and magnesium as suggested on this site.

Also have menieres syndrome, a cause of vertigo, vomiting and partial loss of hearing, also very occasional drop attacks.

As of 8th October on; Mirtazapine 45mg, Citalopram 20mg Lithium 500mg Diazepam 6mg (tapering by 2mg per week) Fish oil and magnesium

As of 25th October Mirt 45mg, Citalopram20mg Lithium 700mg Diazepam12mg

As of 12th November Mirt 37.5 Cit.20mg Lithium 700mg Diazepam 8mg (to taper after 14 days by 10%)

As of 17th November Mirt 35mg Cit 18mg Lithium 600mg Diazepam 8mg (to taper after 14 days by 10%)

As of 25th November MIrt 35mg Cit 18mg Lithium 600mg Diazepam 7mg

As of 1st December MIrt 35 Cit 18mg Lithium 600mg         Diazepam 6mg  (been stable for the last 2 weeks)

GP intervention 19 December now on 150 Ven, 37.5 Mirt, 600 Lithium  Diazepam 7mg

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  • Moderator Emeritus

Hi James, I'm really sorry that you have slipped down the page before getting replies! Your post was moved here to

introductions from tapering, this is your thread to add to and ask questions about your specific taper. 

 

Well done for tapering the other drugs, that is quite an achievement!  How long is it since you finished tapering them?

If it is recently then it would be better for you to hang on for a few months to allow your nervous system to stabilise

properly before starting the quetiapine taper.  If you reacted badly to the cut of 50mg that means the cut was too much for you

and you would be best cutting by a much smaller amount, then waiting at least 4 weeks before another cut. You have been

on a lot of drugs and successfully tapered from several that can be difficult and that could also be why you had the withdrawal

symptoms when you cut the quetiapine.  You have done your homework here and that is great, you may have seen the thread

for tapering quetiapine but in case you have missed it here is the link. 

 

http://survivingantidepressants.org/index.php?/topic/1707-tips-for-tapering-off-seroquel-quetiapine/

 

It would be helpful for us to have your meds history in your signature strip so we can see at a glance what you have

been on and tapered.  Doses and when you tapered would be very helpful too. Here is how to do that.

 

http://survivingantidepressants.org/index.php?/topic/893-please-put-your-withdrawal-history-in-your-signature/

**I am not a medical professional, if in doubt please consult a doctor with withdrawal knowledge.

 

 

Different drugs occasionally (mostly benzos) 1976 - 1981 (no problem)

1993 - 2002 in and out of hospital. every type of drug + ECT. Staring with seroxat

2002  effexor. 

Tapered  March 2012 to March 2013, ending with 5 beads.

Withdrawal April 2013 . Reinstated 5 beads reduced to 4 beads May 2013

Restarted taper  Nov 2013  

OFF EFFEXOR Feb 2015    :D 

Tapered atenolol and omeprazole Dec 2013 - May 2014

 

Tapering tramadol, Feb 2015 100mg , March 2015 50mg  

 July 2017 30mg.  May 15 2018 25mg

Taking fish oil, magnesium, B12, folic acid, bilberry eyebright for eye pressure. 

 

My story http://survivingantidepressants.org/index.php?/topic/4199-hello-mammap-checking-in/page-33

 

Lesson learned, slow down taper at lower doses. Taper no more than 10% of CURRENT dose if possible

 

 

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  • Moderator Emeritus

Just want to add my voice to mammaP's, please give us your med and taper history--what doses were you on, how did you taper, how recently did you come off the other meds? Thanks, we really need to know this in order to answer your question.

 

Also, welcome to the forum, and congratulations on your commitment in getting off those meds--not an easy thing to do!

Started on Prozac and Xanax in 1992 for PTSD after an assault. One drug led to more, the usual story. Got sicker and sicker, but believed I needed the drugs for my "underlying disease". Long story...lost everything. Life savings, home, physical and mental health, relationships, friendships, ability to work, everything. Amitryptiline, Prozac, bupropion, buspirone, flurazepam, diazepam, alprazolam, Paxil, citalopram, lamotrigine, gabapentin...probably more I've forgotten. 

Started multidrug taper in Feb 2010.  Doing a very slow microtaper, down to low doses now and feeling SO much better, getting my old personality and my brain back! Able to work full time, have a full social life, and cope with stress better than ever. Not perfect, but much better. After 23 lost years. Big Pharma has a lot to answer for. And "medicine for profit" is just not a great idea.

 

Feb 15 2010:  300 mg Neurontin  200 Lamictal   10 Celexa      0.65 Xanax   and 5 mg Ambien 

Feb 10 2014:   62 Lamictal    1.1 Celexa         0.135 Xanax    1.8 Valium

Feb 10 2015:   50 Lamictal      0.875 Celexa    0.11 Xanax      1.5 Valium

Feb 15 2016:   47.5 Lamictal   0.75 Celexa      0.0875 Xanax    1.42 Valium    

2/12/20             12                       0.045               0.007                   1 

May 2021            7                       0.01                  0.0037                1

Feb 2022            6                      0!!!                     0.00167               0.98                2.5 mg Ambien

 

I'm not a doctor. Any advice I give is just my civilian opinion.

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Hi, apologies for the delay in replying. It took me most the day to workout I needed to be in Desktop View, not Mobile View to add a signature. I have tried to complete my signature as best I can. Rather difficult in twelve lines but hopefully the information will be of use.

 

Simon, I will try to reply to your post tomorrow.

 

Thank you for the welcome Rhi and MamnaP

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Hi Phandy , yes your signature shows the tapers you did and how fast they were (from the point of view of this forum) But I guess part of the reason for that success is that you weren't on the drugs for any long period (fortunately)

I personally did a taper of 6 weeks for one of the meds im on and crashed after 6 weeks off it , although the intervening period was a welcome relief to near normality I must say and gives me some hope that when this slow, slow taper gets moving, I will again have the capacity to feel emotion and have improved cognition. Both things that the SSRIs have robbed me of.

Did you feel no withdrawal symptoms coming down off the Lithium and the Mirt?

Best of luck with the remainder of your taper, looks like youre out of the woods!

 

Simon

. Been on some kind of meds since 1982,mainly on and off things like imipramine.,2000 on75mg venlafaxine til it bottomed out, then 150, also no good. about 7 years. Almost ct from it and put on cocktail of  Cit, Mirt and Lithium. Remained there for 7 years.

Tapered Citalopram in June2014 and was off in 6 weeks. Mood slumped about 6 weeks later. Found this site sept 5th and got some idea why this happens.18th Sept stopped lorezepam and due to misunderstanding with GP was without it for 36 hours which caused a crisis.

from 19thsept 18mg diazepam to replace lorezepam(possible addiction) 24th sept 12 mg diaz per day. 29th sept 10mg diaz per day and tapering at 1-2mg per week. At 5mg will slow down taper. At same time increase of mirtazapine to 45mg per day.

Taking fish oil and magnesium as suggested on this site.

Also have menieres syndrome, a cause of vertigo, vomiting and partial loss of hearing, also very occasional drop attacks.

As of 8th October on; Mirtazapine 45mg, Citalopram 20mg Lithium 500mg Diazepam 6mg (tapering by 2mg per week) Fish oil and magnesium

As of 25th October Mirt 45mg, Citalopram20mg Lithium 700mg Diazepam12mg

As of 12th November Mirt 37.5 Cit.20mg Lithium 700mg Diazepam 8mg (to taper after 14 days by 10%)

As of 17th November Mirt 35mg Cit 18mg Lithium 600mg Diazepam 8mg (to taper after 14 days by 10%)

As of 25th November MIrt 35mg Cit 18mg Lithium 600mg Diazepam 7mg

As of 1st December MIrt 35 Cit 18mg Lithium 600mg         Diazepam 6mg  (been stable for the last 2 weeks)

GP intervention 19 December now on 150 Ven, 37.5 Mirt, 600 Lithium  Diazepam 7mg

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Hi Simon, sorry for the late reply. I did not feel well whilst withdrawing from any of the medications.

 

I might be different as part of my psych is that I think I deserve to be in pain (a long story which I won't cover here) so whilst withdrawaling can be difficult it is something I feel I deserve to endure.

 

I started my taper of quetiapine on the 1st. I am reducing by 12.5mg every two weeks so I will be reducing by 25mg a month. Please jump in with advice. At this rate it will take me over a year to come off quetiapine.

 

I can cope with most the pain of withdrawl except the panic attacks as they stop me from being able to function.

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Thanks for that . I wish you well.

Im just starting a 10% taper of Lithium and glad to feel im at least at the start of a positive move.

All the best

 

Simon

. Been on some kind of meds since 1982,mainly on and off things like imipramine.,2000 on75mg venlafaxine til it bottomed out, then 150, also no good. about 7 years. Almost ct from it and put on cocktail of  Cit, Mirt and Lithium. Remained there for 7 years.

Tapered Citalopram in June2014 and was off in 6 weeks. Mood slumped about 6 weeks later. Found this site sept 5th and got some idea why this happens.18th Sept stopped lorezepam and due to misunderstanding with GP was without it for 36 hours which caused a crisis.

from 19thsept 18mg diazepam to replace lorezepam(possible addiction) 24th sept 12 mg diaz per day. 29th sept 10mg diaz per day and tapering at 1-2mg per week. At 5mg will slow down taper. At same time increase of mirtazapine to 45mg per day.

Taking fish oil and magnesium as suggested on this site.

Also have menieres syndrome, a cause of vertigo, vomiting and partial loss of hearing, also very occasional drop attacks.

As of 8th October on; Mirtazapine 45mg, Citalopram 20mg Lithium 500mg Diazepam 6mg (tapering by 2mg per week) Fish oil and magnesium

As of 25th October Mirt 45mg, Citalopram20mg Lithium 700mg Diazepam12mg

As of 12th November Mirt 37.5 Cit.20mg Lithium 700mg Diazepam 8mg (to taper after 14 days by 10%)

As of 17th November Mirt 35mg Cit 18mg Lithium 600mg Diazepam 8mg (to taper after 14 days by 10%)

As of 25th November MIrt 35mg Cit 18mg Lithium 600mg Diazepam 7mg

As of 1st December MIrt 35 Cit 18mg Lithium 600mg         Diazepam 6mg  (been stable for the last 2 weeks)

GP intervention 19 December now on 150 Ven, 37.5 Mirt, 600 Lithium  Diazepam 7mg

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I hope you have a safe symptom free withdrawal.

Klonopin 2mg 2000-2005 Tapered off without bad symptoms

Ativan 1mg 2007-2010 Tapered with moderate problems

 

Klonopin 16 total mgs in Jan and Feb 2014 - got dependent and foolishly updosed by bad doctor to 1.25mg for 4 weeks.  Then horrific detox and placed on Neurontin 100mg, bid, Propanolol 40mg prn, Seroquel 100mg qhs and Remeron 15mg qhs.  Quickly dropped Neurontin and Propanolol.   Stuck on other two meds and still having strong symptoms from klonopin cold turkey.  Want someday to be med free and healed again

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Thank you both. A question on the 10% rule. When you reduce by 10% every two or four weeks, are you then supposed to have a stabilisation period before you taper by another 10%?

 

Ex. Decrease quetiapine by 10% over three weeks, then stay on that dose for three weeks before tapering another 10%? I am a little confused on this point.

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Hello Phandy,

Welcome!

April 2014 remeron 45mg.

June 2014 abilify 2.5 remeron wasn't working so abilify was then added

September 2014 woke up with anxiety x 100!!!!

Pdoc then took me from 45 to 7.5 within a month and took abilify from 2.5 to 0

Currently

Remeron 7.5

Vitamin d 5,000 iu taking for about 3 years

October 2014 added fish oil/omega 3 1000 mg per day

Levothyroxitine 100 10 years or so

Dec 2014 started tapering 10% every 10 days-no problems.

August 2015 down to 0.1 mg

Woke up with severe anxiety-sleep issues-racing thoughts-depression. 9/9/15 up dose 1 mg.

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  • Moderator Emeritus

Thank you both. A question on the 10% rule. When you reduce by 10% every two or four weeks, are you then supposed to have a stabilisation period before you taper by another 10%?

 

Ex. Decrease quetiapine by 10% over three weeks, then stay on that dose for three weeks before tapering another 10%? I am a little confused on this point.

We recommend tapering no more than 10% of the current dose with at least 4 weeks between cuts.  So if you take 50mg you would cut to 45 then hold for 4 weeks or more before making the next cut which would be 4.5mg.  If you are feeling any withdrawal symptoms following a cut it is best to hold until they have passed and your brain has caught up. It is about listening to your body rather than following the calender.  When you are experiencing side effects from a drug they will lessen as the dose gets smaller as side effects are usually dose related. 

**I am not a medical professional, if in doubt please consult a doctor with withdrawal knowledge.

 

 

Different drugs occasionally (mostly benzos) 1976 - 1981 (no problem)

1993 - 2002 in and out of hospital. every type of drug + ECT. Staring with seroxat

2002  effexor. 

Tapered  March 2012 to March 2013, ending with 5 beads.

Withdrawal April 2013 . Reinstated 5 beads reduced to 4 beads May 2013

Restarted taper  Nov 2013  

OFF EFFEXOR Feb 2015    :D 

Tapered atenolol and omeprazole Dec 2013 - May 2014

 

Tapering tramadol, Feb 2015 100mg , March 2015 50mg  

 July 2017 30mg.  May 15 2018 25mg

Taking fish oil, magnesium, B12, folic acid, bilberry eyebright for eye pressure. 

 

My story http://survivingantidepressants.org/index.php?/topic/4199-hello-mammap-checking-in/page-33

 

Lesson learned, slow down taper at lower doses. Taper no more than 10% of CURRENT dose if possible

 

 

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Ok. My plan is this. Drop by 12.5mg for 15 days (I started on 1st) then drop another 12.5mg for the next 15 days (take me to Dec 30th). Therefore dropping 25mg in one month. I don't want to drop by 25mg and stay on that dose for one month.

 

On my plan I will have incrementally dropped by 25mg in one month.Then on the 1st Jan I intend to follow the above tapering plan. Drop another 12.5mg for the first 15 days, then another 12.5mg for the next 15 days, thereby dropping another 25mg in Jan and bring my total taper at the end of Jan to be 50mg. I will then be on 400mg of Quetiapine, down from 450. I intend to follow this schedule until I get to 0.

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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How are you feeling after your first drop.

Klonopin 2mg 2000-2005 Tapered off without bad symptoms

Ativan 1mg 2007-2010 Tapered with moderate problems

 

Klonopin 16 total mgs in Jan and Feb 2014 - got dependent and foolishly updosed by bad doctor to 1.25mg for 4 weeks.  Then horrific detox and placed on Neurontin 100mg, bid, Propanolol 40mg prn, Seroquel 100mg qhs and Remeron 15mg qhs.  Quickly dropped Neurontin and Propanolol.   Stuck on other two meds and still having strong symptoms from klonopin cold turkey.  Want someday to be med free and healed again

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To be honest it has only been a few days...no noticeable changes. I expect to feel different once I have dropped by a 100mg. It is just so hard to tell.

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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How are you doing.

Klonopin 2mg 2000-2005 Tapered off without bad symptoms

Ativan 1mg 2007-2010 Tapered with moderate problems

 

Klonopin 16 total mgs in Jan and Feb 2014 - got dependent and foolishly updosed by bad doctor to 1.25mg for 4 weeks.  Then horrific detox and placed on Neurontin 100mg, bid, Propanolol 40mg prn, Seroquel 100mg qhs and Remeron 15mg qhs.  Quickly dropped Neurontin and Propanolol.   Stuck on other two meds and still having strong symptoms from klonopin cold turkey.  Want someday to be med free and healed again

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  • Moderator Emeritus

Hope the taper goes well for you Phandy, it seems like you have worked it out well and it is under the 10% that

we usually recommend per month and hopefully you wont get any withdrawal symptoms.  :)

**I am not a medical professional, if in doubt please consult a doctor with withdrawal knowledge.

 

 

Different drugs occasionally (mostly benzos) 1976 - 1981 (no problem)

1993 - 2002 in and out of hospital. every type of drug + ECT. Staring with seroxat

2002  effexor. 

Tapered  March 2012 to March 2013, ending with 5 beads.

Withdrawal April 2013 . Reinstated 5 beads reduced to 4 beads May 2013

Restarted taper  Nov 2013  

OFF EFFEXOR Feb 2015    :D 

Tapered atenolol and omeprazole Dec 2013 - May 2014

 

Tapering tramadol, Feb 2015 100mg , March 2015 50mg  

 July 2017 30mg.  May 15 2018 25mg

Taking fish oil, magnesium, B12, folic acid, bilberry eyebright for eye pressure. 

 

My story http://survivingantidepressants.org/index.php?/topic/4199-hello-mammap-checking-in/page-33

 

Lesson learned, slow down taper at lower doses. Taper no more than 10% of CURRENT dose if possible

 

 

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  • 1 year later...

Hi, so two years have passed since i last posted. I have recently completed by Lorazepam taper after about 11 months of tapering. The 13 months prior to that were spent tapering off 450mg of Quetiapine. I am now medication free. I feel content and stable, and for me, coming off my medication was a gamble and struggle that payed off. I realise I have only been off the benzos for about 5 weeks, but it has taken close to a year to get to this stage. I think I was on them for about 5 years. 

 

I am posting to say, you can do it. It is a struggle, and for long periods I felt very ill. The only advice I can give is: SLOW, SLOW, SLOW. That's to taper as slowly as possible. When I was coming off some of the medication - listed in my signature - I was impatient, and tapered far too quickly and became ill very quickly. After my withdrawl experiences, I started to stop creating short term withdrawl plans for myself and just chilled, and said to myself, if it takes a year to taper off 1mg of lorazepam, it takes 1 year. If it takes 2 years, it takes 2 years. 

 

There are no magic answers or pills to make it easier, just take it slowly. If it takes 20 years, it takes 20 years.

 

I hope this post shows that there is some light at the end of the tapering tunnel. :)

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Phandy

 

Which medication was hardest to taper?

 

How long did it take to taper your quetiapine, and did it get harder at lower doses?

 

Thanks

Been taking paroxetine 20 mg for 20+ years for depression. Taking 300 mg of wellbutrin since October 2015 for adhd and depression. Take fish oil, calcium, and a multivitamin. Started taking risperidone late January 2015 3mg for a misdiagnoses of bipolar. Started tapering risperidone late July 2016. As of late September tapered down to 2mg at 5% a week off current dose. Oct 21/2016 1.58 mg Nov 21/2016 1.26mg No withdrawals so far.

 

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Phandy,

 

I'm so glad to hear that you've successfully tapered of 450mg of seroquel. It's give hope for tapering of 300mg of seroquel which i'm planning to do as soon as I stabilizes. My question is did you have help from your doctor or did u do it on your own like cutting up pills and making liquid suspension?

Aug 2016- start on 1mg of respiradone for psychotic symptoms

Sept 2016 - stopped respiradone cold turkey after one month - when into relapse - went to hospital and put on 1mg of respiradone again

Nov 15 2016 - reduced to 0.75mg

Nov 22, 2016 - went back up to 1mg - felt like sever lack of sleep is going to bring back pyschosis

Nov 24, 2016 - going back to the hospital and switching to seroquel to help with sleep

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Phandy

 

Which medication was hardest to taper?

 

How long did it take to taper your quetiapine, and did it get harder at lower doses?

 

Thanks

Hi, I would say the hardest to withdraw from were Mirtazapine and Lorazepam. 

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Phandy, I'm so glad to hear that you've successfully tapered of 450mg of seroquel. It's give hope for tapering of 300mg of seroquel which i'm planning to do as soon as I stabilizes. My question is did you have help from your doctor or did u do it on your own like cutting up pills and making liquid suspension?

Hi, in the UK so liquid variants of medication are not the norm unless you are in Hospital. I tapered by reducing the physical pills, the smallest being 25mg. Obviously if you cut that in half you get 12.5mg etc.  There was not much help any doctor could give, so after I informed them I was tapering from 450 to 0 , I just went ahead and started to taper.

 

I knew I had to go through the pain of withdrawl and what I did not want, and what the doctors can only offer, is more pills to help with the withdrawl. My personal mantra, is that is you need more medication to cope with the side effects of the medication you are tapering from: you are tapering too quickly, 

It took me around 12 months to get to 0. I did not have a strict taper schedule, I just managed drops of around 12.5mg every week or so. 

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Phandy,

 

We're u on the extended release seroquel?

 

When I begin my taper I want to start by cutting the pills but is concerned with dosage dumping as i'm taking the 300mg extended release one. My doctor is no help as she doesn't believe in slow tapering so I may have to do this alone. I had ask her to switch me to the immediate release seroquel but she refuses. So if u succeed with cutting up extended releases seroquel it would be good information for me to know.

 

Thank you

 

Aug 2016- start on 1mg of respiradone for psychotic symptoms

Sept 2016 - stopped respiradone cold turkey after one month - when into relapse - went to hospital and put on 1mg of respiradone again

Nov 15 2016 - reduced to 0.75mg

Nov 22, 2016 - went back up to 1mg - felt like sever lack of sleep is going to bring back pyschosis

Nov 24, 2016 - going back to the hospital and switching to seroquel to help with sleep

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Hi Salaw, yes I was using the extend release Quetiapine. I think it was called Quetiapine XL on the box. If I remember, mine came in 25mg/50mg/150/mg/300mg and 400mg.

 

You need to get your monthly prescription of 300mg in 25mg tablets so it easier to begin your taper. 

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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Well done phandy!! I'm on my 10 day of coming off quitiapine. It's a challenge but l'm up for it.

 

Warm wishes

 

hopeful

Quit quitiapine on 2nd December 2016. Dosage 150mg.Been on it since April/May 2015.Take 30mg of amytriptaline as a neuropathic.

Previous meds 1995-2015 - moclobimide ,trazadone, paroxatine,fluoxetine,sertraline,citrilopram,mirtizapine,dothiepin,doxipin ,venlavaxine and buproprion.

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Good luck mate. 

Diagnosis 2011: Psychotic Episode/Psychotic Depression. Current Diagnosis: 2014: Depression/Anxiety/Borderline Personality Disorder.
Medication: 2011 Prescribed in 4 weeks (In Hospital) Olanzapine (Switched to Quetiapine 450mg), Venaflaxine 75mg, Lithium 1200mg, Mirtazapine 45mg, Zopiclone 7.5mg x 3 & Lorazepam 1-3mg. 2012/2013 Electroconvulsive Therapy (16 treatments) 8 in 2012 & 8 in 2013.
2014 Taper: Jan - Feb Venaflaxine 75mg to 0. March - May: Mirtazapine 45mg to 0. Aug - Nov Lithium 1200 to 0.
2015 Quetiapine 450mg-0mg, 2016 Lorazepam 1mg-0mg.

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  • 2 years later...
  • Administrator

Hello, phandy, how are you doing?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

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