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About reinstating and stabilizing to reduce withdrawal symptoms


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  • Moderator Emeritus

@Manati

 

Please ask questions about your own situation in your Introduction topic.  This way your history will all be in one place and it is easier for the mods to access previous history.  Thank you.

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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2 hours ago, ChessieCat said:

@Manati

 

Please ask questions about your own situation in your Introduction topic.  This way your history will all be in one place and it is easier for the mods to access previous history.  Thank you.

 

Oh sorry -  I didn't mean to hijack the thread for my own concerns, and will stick to my intro topic with those questions! 🙈

Fluoxetine (Prozac) (25mg?) from December 2002 - November 2005 for anxiety/depression

Effexor (Venlafaxine) Retard (75mg) due to Panic attacks from November 2005 until around May 2020 when I started tapering off from 75mg to about 33mg in September. Accidentially missed a dose and naively went cold turkey from around 33mg to zero on 26th of September. Hell broke loose in early December.

25th December: Reinstated Venlafaxine with one bead (0.3/0.4mg) in the evening, proceeding with two beads (0.7/0.8mg)

since 5th January: 3 beads of Venlafaxine daily and nothing else except fish oil and magnesium. No changes in daily routine

15th January - 17th January: 4 beads of Venlafaxine

since 18th January: back to 3 beads of Venlafaxine due to extreme agitation, introduced Ashwaghanda supplement.

Since 23. January: introduced Lyrica to help with sleep/jerks keeping me awake: updosed from 4mg to 8mg.

Since February: 700mg Valerian and 2mg Melatonin for sleep

March: tapering Lyrica again due to side effects.

April: down to 2 beads of Venlafaxine

17th October: Off everything. Braindead, apathetic/anhedonic Zombie.

 

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  • 2 months later...

Anyone felt even worse when reinstating after 2 1/2 months? I was finally doing better but took the path of reistating and I got so bad and depressed . My depression wasn t even back. Why is my brain reacting so bad at this? Anyone felt worse? 

JUNE 2019 Tried Coaxil ,wellbutrin, cipralex, mirtazapine, effexor, sertraline, benzoS for 5 months.November 2019 started prozac 30 mg, took till May 2020 and started tapering 5 mg at a time till reached 2.5mg once every 2 3 days.January 2020 stopped benzos (tapered for 2 months).27 December 2020 stopped Prozac, 2 bad weeks.January and  february was feeling well.I am taking 2 mg of lorazepam /year.Tried 5Htp 100mg Febr 2020 for a copule of days, vomited non stop. Stopped right away.No supplements, possibly allergic to excipients now. 30 mg of Ulipristil acetate on 25th of febr.

Reinstated 0.4 mg of prozac 12 march  , had 0.2mg 13 march. Stopped reinstatement, feeling better.

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14 hours ago, Melany said:

Anyone felt even worse when reinstating after 2 1/2 months? I was finally doing better but took the path of reistating and I got so bad and depressed . My depression wasn t even back. Why is my brain reacting so bad at this? Anyone felt worse? 

Yup!! I think alot of people on here have, that's part of the risk of reinstating. 

How long have you reinstated for? You could go back to your regular dose if you haven't been reinstated for too long. Either way, it's going to be a matter of patience waiting for your brain to regulate itself.

10 years on various anti-depressants

5 years Effexor xr

tappered of 150mg in 6 months

nothing for two weeks

Reinstated 15 beads for 50 days

Tappered off then clean 2-3months

gradually went back up to 13 mg 3 years

bridged fluoxetine 10mg

2 week tapper

1 year clean

reinstated 5ml dispersed fluroxatine for 6months

 

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How can we tell if it s the reinstatement that makes us feel worse or the WD that got worse?

Should I pause for 2 3 days? See if I get better?

JUNE 2019 Tried Coaxil ,wellbutrin, cipralex, mirtazapine, effexor, sertraline, benzoS for 5 months.November 2019 started prozac 30 mg, took till May 2020 and started tapering 5 mg at a time till reached 2.5mg once every 2 3 days.January 2020 stopped benzos (tapered for 2 months).27 December 2020 stopped Prozac, 2 bad weeks.January and  february was feeling well.I am taking 2 mg of lorazepam /year.Tried 5Htp 100mg Febr 2020 for a copule of days, vomited non stop. Stopped right away.No supplements, possibly allergic to excipients now. 30 mg of Ulipristil acetate on 25th of febr.

Reinstated 0.4 mg of prozac 12 march  , had 0.2mg 13 march. Stopped reinstatement, feeling better.

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5 hours ago, Melany said:

How can we tell if it s the reinstatement that makes us feel worse or the WD that got worse?

Should I pause for 2 3 days? See if I get better?

Usually, for me, if the reinstatement works I feel better very quickly. 

 

You will feel better eventually either way, it's a matter of whether its worth upping your dose if your going to have to go through withdrawal symptoms until your brain levels out anyway. 

10 years on various anti-depressants

5 years Effexor xr

tappered of 150mg in 6 months

nothing for two weeks

Reinstated 15 beads for 50 days

Tappered off then clean 2-3months

gradually went back up to 13 mg 3 years

bridged fluoxetine 10mg

2 week tapper

1 year clean

reinstated 5ml dispersed fluroxatine for 6months

 

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Thanks ! I ve delayed my dose and feeling ok so far. We ll see in a few days what happends and then tough it up and deal with it  whatever it is.

JUNE 2019 Tried Coaxil ,wellbutrin, cipralex, mirtazapine, effexor, sertraline, benzoS for 5 months.November 2019 started prozac 30 mg, took till May 2020 and started tapering 5 mg at a time till reached 2.5mg once every 2 3 days.January 2020 stopped benzos (tapered for 2 months).27 December 2020 stopped Prozac, 2 bad weeks.January and  february was feeling well.I am taking 2 mg of lorazepam /year.Tried 5Htp 100mg Febr 2020 for a copule of days, vomited non stop. Stopped right away.No supplements, possibly allergic to excipients now. 30 mg of Ulipristil acetate on 25th of febr.

Reinstated 0.4 mg of prozac 12 march  , had 0.2mg 13 march. Stopped reinstatement, feeling better.

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  • 2 weeks later...

I have read through this entire topic again.  My impression when I first read it was that reinstatement is not recommended after being several months off.  This time it seems that any time reinstatement occurs, it should be at a very minimum dose to start and that amount of time off does not always mean you should not try reinstatement.  Is that correct?

I also want to clarify if you reinstate at say.5 and it creates problems, do you still taper off @10% or just stop.


My situation is dire at 18 months off, so trying to figure this out. I did post my specifics on my own thread, but have not received a response.  I addressed that post to @Altostrata but I know all of you are very busy, so thought I would go back through this thread.  I do appreciate all this information and the time you spend creating and monitoring it.  

 

 

 

 

 

 

Mid and late 1990s various antidepressants including Prozac, Pamelor, Zoloft, Trazadone for brief periods of time  Usually one month or less with no taper.

1998 to August 2020   .5 mg lorazepam, first PRN then daily. CTed Jan 2015 RI March 2015 (6 wks): CTed October 2016 RI Nov 2016 (3 wks (October 2016). 10 month taper begin Oct 2019 finished Aug 10, 2020. 2000 to Sept 2015 periodic use Escitalopram 10 mg.  Brief periods, 3-6 months, with rapid tapers or cold turkeys.Oct 2016 Cymbalta and Remeron for a period of about 2 weeks. Stopped cold turkey.Nov 2016 to October 2017 10 mg escitalopram.  One month taper

Last 2 ½ years:

Ongoing daily .5 lorazepam originally began in 1998 PRN, then daily 2008.  March 2019 to August 2019 10 mg escitalopram; rapid taper about 3 weeks. Sept 2019 to Sept 2019 Pristiq 25mg, taken 2 weeks then a every other day taper for one week.  25 mg trazadone for one week, no taper.  Zoloft 25 mg for 5 days, no taper. October 2019 -August 2020 10 month taper from .5 lorazepam.

Currently taking Valsartan 40 mg daily and Preservision AREDS2 one capsule daily.

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  • Moderator Emeritus

@JustBella

 

Post #1 of this topic explains what to do if you start to feel worse after reinstating.

 

Reinstatement is basically a gamble whether you reinstate after a few months or many months.  We have seen it work/fail for both time spans.  It seems that the sooner you reinstate/updose (usually starting with a small amount) after experiencing withdrawal symptoms the better chance there is of it being successful.

 

Generally SA suggests reinstating the last drug that you took.  However if you have been off a drug for longer than a few months, or the drug you stopped is one that is difficult to taper (either because of the physical difficulty of getting doses OR side effects), changing to a different drug like Prozac or citalopram is an option that might work.

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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i went back on prozac after struggling for 2 years with crippling ocd and anxiety. i started at a tiny dose and gradually increased over a year with very little benefit. eventually i bit the bullet and went back on 40mg, the dose i originally took. it took a long time to work - over 3 months before i saw a difference but now 4 years later i'm feeling a whole lot better and i can see the sunshine again. i wish i'd bitten the bullet sooner and gone back to my original dose. 

Took prozac 40 mg for 20 years.

January 2017 started cutting down prozac by 12.5% a week. End of February 2017 completely off prozac and withdrawals began.

Currently taking Levothyroxine 75 mcg, Magnesium citrate 200mg,Sage leaf 50mg daily

Amlodipine: October 2017 , discontinued 26 Feb 2019; Candesartan:  26 Feb 2019, 4mg.

Discontinued magnesium citrate 200mg Apr 3rd 2019

Reinstated prozac:  14 Jan 2019, 1mg; 26 Jan, 1.5mg; 4 Feb, 2mg; 16 Feb, 2.5mg; 2 Mar, 3mg; 5 Mar, 2.5mg, 23 Mar, 3 mg; 6 Apr, 3.5mg, 14 Apr 4mg, 23 Apr 5mg, 10 Jul 8mg, 1 Dec 20mg, 1 Apr 2020 40mg 

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  • Moderator Emeritus

@thecowisback

Please update your drug signature.

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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  • 5 months later...

Alto it seems that all references to reinstatement come from the point of view of having come completely off drug. Is my situation still considered reinstatement where I only made 2 10% cuts albeit too quickly?

1996 started Paxil for anxiety 

2012 20mg reduced to 10mg 2 week period went back up to 20

March2021 dropped from 20-15mg held 2 weeks dropped 2.5mg held 4weeks back to 20mg

July 3 2021 dropped 10% 2mg held 2 weeks

July 17 2021 dropped 1.8mg held 2 weeks 

july 31 2021 dropped 1mg

August 3 2021 raised 1mg Held until august 20 2021 raised back to 20mg

current dose 20mg

dr. Raised to 30 mg because of symptoms 

hospital psych took me off Paxil over a week started me on Zoloft 

current Zoloft 100 mg

klonapin 1-2 mg as needed 

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  • Administrator

Your changes would be updosing.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Ok thanks 

1996 started Paxil for anxiety 

2012 20mg reduced to 10mg 2 week period went back up to 20

March2021 dropped from 20-15mg held 2 weeks dropped 2.5mg held 4weeks back to 20mg

July 3 2021 dropped 10% 2mg held 2 weeks

July 17 2021 dropped 1.8mg held 2 weeks 

july 31 2021 dropped 1mg

August 3 2021 raised 1mg Held until august 20 2021 raised back to 20mg

current dose 20mg

dr. Raised to 30 mg because of symptoms 

hospital psych took me off Paxil over a week started me on Zoloft 

current Zoloft 100 mg

klonapin 1-2 mg as needed 

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  • 2 months later...

Looking back, reinstating made everything so much worse for me, so please think thrice about it once you're more than 3 months out!!

Fluoxetine (Prozac) (25mg?) from December 2002 - November 2005 for anxiety/depression

Effexor (Venlafaxine) Retard (75mg) due to Panic attacks from November 2005 until around May 2020 when I started tapering off from 75mg to about 33mg in September. Accidentially missed a dose and naively went cold turkey from around 33mg to zero on 26th of September. Hell broke loose in early December.

25th December: Reinstated Venlafaxine with one bead (0.3/0.4mg) in the evening, proceeding with two beads (0.7/0.8mg)

since 5th January: 3 beads of Venlafaxine daily and nothing else except fish oil and magnesium. No changes in daily routine

15th January - 17th January: 4 beads of Venlafaxine

since 18th January: back to 3 beads of Venlafaxine due to extreme agitation, introduced Ashwaghanda supplement.

Since 23. January: introduced Lyrica to help with sleep/jerks keeping me awake: updosed from 4mg to 8mg.

Since February: 700mg Valerian and 2mg Melatonin for sleep

March: tapering Lyrica again due to side effects.

April: down to 2 beads of Venlafaxine

17th October: Off everything. Braindead, apathetic/anhedonic Zombie.

 

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I have been 13 months off Zoloft. It is not getting any better

 

Thinking of reinstating 13 months off. Anyone did that after so long off? Thoughts?

 

Original dose 50 mg

Zoloft, November 2019.  I worked up to 50 mg and stayed there until 1 year later. I tapered for 3 months, which should consider to be cold turkey.
Tapering schedule:
Month 1: 37.5 mg

Month 2: 25 mg

Month 3: 12.5 mg

Month 4(Half the month): 6.75 mg
Month 4(Other half): 0 mg December 9, 2020

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  • Moderator Emeritus
4 minutes ago, curiousnootropics said:

Thinking of reinstating 13 months off.

 

After such a long time off the drug if you did decide to reinstate it is better to start of with a very tiny tester dose to see how you respond.  The idea of this is not to reduce the withdrawal symptoms but to see how you respond to the drug.

 

Please make sure that you carefully read all of Post #1 of this current topic.

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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7 minutes ago, ChessieCat said:

 

After such a long time off the drug if you did decide to reinstate it is better to start of with a very tiny tester dose to see how you respond.  The idea of this is not to reduce the withdrawal symptoms but to see how you respond to the drug.

 

Please make sure that you carefully read all of Post #1 of this current topic.

What would be a dose to consider? Like 1 mg? How fast would you feel improvement?

Zoloft, November 2019.  I worked up to 50 mg and stayed there until 1 year later. I tapered for 3 months, which should consider to be cold turkey.
Tapering schedule:
Month 1: 37.5 mg

Month 2: 25 mg

Month 3: 12.5 mg

Month 4(Half the month): 6.75 mg
Month 4(Other half): 0 mg December 9, 2020

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  • Moderator Emeritus
8 minutes ago, curiousnootropics said:

What would be a dose to consider? Like 1 mg?

 

If it was me I would be testing with 0.25mg.  It is better to start with a small amount than to risk taking too much.  And if you have no issues with the test dose you could increase by small amounts gradually.

 

The idea of reinstating is NOT to get rid of withdrawal symptoms completely but to bring them to a bearable level.

 

It takes about 4 days for a dose to get to full level in the blood and a bit longer for it to register in the brain.

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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10 hours ago, ChessieCat said:

 

If it was me I would be testing with 0.25mg.  It is better to start with a small amount than to risk taking too much.  And if you have no issues with the test dose you could increase by small amounts gradually.

 

The idea of reinstating is NOT to get rid of withdrawal symptoms completely but to bring them to a bearable level.

 

It takes about 4 days for a dose to get to full level in the blood and a bit longer for it to register in the brain.

 

How long would it take to feel a severe adverse reaction during reinstatement? I possibly had a kindling reaction while trying to go back on Lexapro, but it took about 3 weeks to feel it.

Risperdal 2012

Lexapro 2013-2020

30mg Lexapro from 2016-2020

30mg cold turkey in June 2020 due to issues with APRN

Re-instatement of 10mg of Lexapro in late September 2020 due to panic attack

Cold turkey 10mg Lexapro early October 2020 due to sudden health problems possibly caused by Lexapro

Now taking 20mg of Lisinopril. Stopped iron supplement over the counter for low iron due to feeling sick while taking it. Taking a vitamin D supplement alongside the Lisinopril.

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  • Moderator Emeritus
8 hours ago, rilexapro said:

How long would it take to feel a severe adverse reaction during reinstatement?

 

18 hours ago, ChessieCat said:


Please make sure that you carefully read all of Post #1 of this current topic.

 

 

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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