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Tips for tapering off Wellbutrin, SR, XR, XL / Zyban (buproprion)


Altostrata
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@Colonial I did that once too! ūü§£ Overtired, I guess!

Now: 100 mg Zoloft am,¬†50 mg¬†Trazodone bedtime.¬† Daily drug burden decreased from 2050 in 2018 mg to 150 mg¬†ūüźĘūüźĘ

Zoloft: 5/7/22 cut 12.5 mg 3/20/22 cut 12.5 mg 10/26/21 cut 6 mg 10/17/21 cut 5 mg, 9/17/21 Cut 3 mg,  9/13/21 cut 4 mg, 8/29/21 Cut 2 mg 8/8/21 Cut 3 mg  7/30/21 Zoloft: Converted 25 mg to liquid. Also take 100 mg pill & 25 mg pill=150 mg total
ūüĆě Feb 28, 2021 0 mg Gapapentin 2021 Gaba each dose 4x/day: Feb 27 7 mg (one dose only), Feb 10, 7 mg, Jan 14 10 mg 2020 Current taper schedule from Aug 30-present: drop 8 mg every 2-3 weeks. Aug 20 31 mg, Aug 18, 33 mg, July 29, 35 mg, July 23 38 mg, July 22 40 mg Jun 24 42 mg, Jun 15 44 mg, Jun 9 48 mg, May 22 50 mg, May 14 54 mg, May 7 56 mg, Apr 16 58 mg, Mar 28 60 mg, Mar 18 62 mg. Feb 26 64 mg. Feb 19, 66 mg. Jan 23, 70 mg. 2019 Dec 19, 72 mg. Nov 14 ,76 mg. Aug 8, 80 mg. Aug 6, 85 mg. Jul 26, 90 mg.¬†Jul 11, 95 mg.

Jul 16 trazodone from 100 to 50 mg.

Jun 17-July 10 Slowly changed gab fr pill to liquid at same dose 100 mg 4x/d.

Apr 24 Stopped klon!!!¬†ūüĆě Apr 4¬† Decreased gaba to 400 mg (100 mg 4x/day)-Apr 4, 2019¬†¬† 0.25 klon March 11¬† Klonopin .5 mg twice daily, varied dose til Apr 15. Started Klon fast taper 25%, short use

Mar 16, 450 mg gaba 3x/day cut 600 mg--not exact!--updose after learning w/d

Feb 20, 2019 1800 mg gabapentin; MD taper; off 3 days=mvt disorder & autonomic instability. July 2018 temazepam 15 mg 1-2; prn several x/wk til Jan/Feb 2019 when cold turkey, flu illness for months

July 2018 started gabapentin 100 3x/day; titrated up to 1800 mg (600 3x/day)

Buspar, I forget how much, 2 pills a day Jan 2017-July 2018 cold turkey. On Zoloft since maybe 2004? After trying many.

*I speak from my experience. Nothing I say is medical advice. I'm not a doctor.

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  • 3 weeks later...

Hi Guys,

 

I am on 300mg per day of Zyban SR ( 150mg twice a day ) And I need to know if I can crush the entire x2 Zyban SR 150mg pills and then divide the dose into 3 equal amounts and take 3 times a day like IR pills. I understand that the SR pills have binders in them. 

 

Plan would be for first 10% drop being 30mg for a month - 90mg at 6am, 90mg at 12pm, 90mg at 6pm. Total 270mg per day. This would be 300mg Zyban SR pills crushed and divided. 

 

Has anyone done this above with SR pills?

 

Also with changing from SR twice a day to now IR 3 times a day, would it be suggested I do the first month at my normal 300mg per day to get use to the change or should I just the first drop at the same time?

 

Many thanks guys. Your all awesome.

2015 - Started Zoplicone for sleeping off & on for 5 years ( No more than a week to 10 days at time )

2016 - Stared Thyroxine as I have Hasimotos Hypothyroid ( Still taking today 25mg )

2019 - Problems with Zoplicone started, Tried Temazepham with same problems

2020 - June - Had massive problems with trying different medications and had a breakdown

2020 -  July - Started 6mg Diazepam to help with side effects of Zyban ( Bupropion ) 300mg  

2020 - August - Started Diazepam taper as I have a dependence to Benzo's ( Funny that after they said zoplicone was not a benzo...)

2020 - Oct - 1.2mg diazepam ( Have had 5 major withdrawls since Aug )

 

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  • 10 months later...

Hi @Altostrata

 

is it ok cutting bupropion IR into quarters or smaller piece?  How do you know the medicine is evenly distributed.  I have been cutting my 75mg IR into 1/8 pieces and using a scale to get precise measurement but I wonder if I should crush whole tablet completely and mix the powder before measuring out dose. What do you think?

 

thank you for this site!

1995 - 2001 Wellbutrin & Effexor, 2001 Stop Effexor (CT), Start Celexa. 2009 Start Trazodone, 2010 Stop Celexa (fast taper), Start Cymbalta. 2014, 2016 Reductions in Dosages Cymbalta and Wellbutrin
2018 Started Slow Taper of Cymbalta from 30mg

2021 May Trazodone Dose drop from 75 to 50 - Started Muscle Cramping and Spasms
2021 July 5th Stopped Cymbalta After 3 YR Taper (No method, I removed beads based on how I was feeling.  Got down to 4 beads, or about 0.4mg before stopping)
2021 July 5th Stopped Wellbutrin cold turkey (was taking 75mg.  Over last week on Wellbutrin, I skipped days taking 100mg SR every other day).  Took last dose of Wellbutrin July 5th.  Severe WD Started July 17th.
2021 Aug 3rd:  Start Remeron 7.5mg at Night 

2021 Aug 23rd: Reinstated Wellbutrin 10mg AM / 10 mg PM, Stopped Remeron

2021 Aug 30th: Changed WB Dosing to 10mg AM / 5mg Mid Day / 8mg Early Evening

2021 Sept 1st: Reinstated Remeron 7.5mg for sleep

2021 Sept 14th: Changed WB to 10mg AM / 6mg Mid day / 6mg Early Evening, Jan 24: Changed WB to 9mg AM / 6mg Mid Day / 6mg PM

2021 Sept 21: Re-instated Cymbalta at 1 bead 2X a day, Oct 12:  Updosed to 2 beads AM, 1 bead PM, March 11:  Updosed 2 beads AM, 2 beads PM
Currently on Trazodone 50mg and Remeron 7.5mg.  Cymbalta 2 Beads (0.1mg) 2X Day 7AM and 6PM.  Wellbutrin 9mg AM / 6mg Mid day / 6mg Early Evening

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  • Administrator

@SonSetFree Please read this topic from the beginning.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 8 months later...

I'm planning for my tapering. Is it true that it is only possible with IR tablets to transform it into liquid? I am taking 300 mg XR and would prefer to convert it into liquid because there might be trouble with the prescription.

2003- June 2019: Tavor (few weeks), Unknown, Paroxetine, Bupropion (Wellbutrin). A few times tapering OFF (in shortest time) and taken again.

July 2019: Tapering Paroxetine 40 mg- OFF (a few weeks). Started Cymbalta at the same time (up to 90 mg).

December 26, 2020: Cymbalta cold turkey  

OFF all medications

November 23, 2021: Started Paroxetine 10 mg 2 days, 5 mg 2 days, OFF 

OFF all medications

February 2022: Started Mirtazapin (15 mg), Started Bupropion (150 mg), Risperdal for 4 days (0,5- 1 mg)

April 2022: Mirtazapin tapering for two days (7,5 mg), then increased again to 15 mg.

Bupropion increased to 300 mg. Lithium startet up to 675 mg. Tavor for 3 weeks (0,5-1,5 mg/d)

Current: 675mg Lithium, 300mg Bupropion, Tapering Mirtazapin:

May 10, 2022: 15mg to 7,5mg; June 17 6,75mg

Supplements: Fish oil (1500 EPA/DHA),¬†400 I.U. Vitamin E , 100mg Magnesium, 500 I.U. Vitamin D3, 500őľg Vitamin B12

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  • Moderator Emeritus
11 hours ago, Dany said:

I'm planning for my tapering. Is it true that it is only possible with IR tablets to transform it into liquid? I am taking 300 mg XR and would prefer to convert it into liquid because there might be trouble with the prescription.

 

Did you read Post #1 of the current topic which explains the various ways to get non standard doses.  Please read it very carefully, you might need to split your dose and take it more than once a day.  It includes the following information:

 

On 7/17/2011 at 6:28 AM, Altostrata said:

If you cut up Wellbutrin or bupropion XR, what's inside is regular immediate-release bupropion. When you break the time-release coating, the tablet loses its extended-release characteristic and you would be taking immediate-release bupropion.

 

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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On 6/1/2022 at 6:12 AM, Dany said:

Is it true that it is only possible with IR tablets to transform it into liquid?

 

That is correct.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 2 weeks later...

Wellbutrin XL taper tips

 

Looking for any tips anybody has for being able to taper off Wellbutrin 150mg XL ? I have read the Wellbutrin section but was wondering if any real experience of tapering off it ? 

 

Edited by ChessieCat
added topic title before merging with existing topic

On Prozac 20 mg from 1996 to 2012 started for post partum depression ? Pooped out

2012 - Switched to 1.25 mg Klonopin ( tapered off last dose march 6 th / 2017 ( 14 month taper) 

2012-15 mg lexapro came off nov.4 th /17 

2012- 150 mg Wellbutrin xl ( still on ) 
2019- Stabilized to be functional after coming off lex and klon waiting to get healthy to taper Wellbutrin

2021 Dec - Suprax and macrobid for UTI

2022 Jan - withdrawal symptoms came back with a vengeance ( antibiotics and uti only change ) 

2022 June - still in full withdrawal 

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  • Moderator Emeritus

@Soup

 

Have you read through this current topic?  (I moved your post here).

 

You could try doing a search for members who are taking Wellbutrin / buproprion and visit their Intro topics to see what version they are taking.  If they are taking the same version as you, then you could make a post in their topic asking how they are tapering it.

 * * * * * *   PLEASE WATCH THIS VIDEO   * * * * * *

Antidepressant Withdrawal Syndrome and its Management

 

MISSION ACCOMPLISHED:    (6 year taper)      0mg Pristiq      on 13th November 2021

Woohoo!!!  Finally off Pristiq    Post 0 updates start here

ADs since ~1992:  25+ years - 1 unknown, Prozac (muscle weakness), Zoloft; citalopram (pooped out) CTed (very sick for 2.5 wks a few months after); Pristiq:  50mg 2012, 100mg beg 2013 (Serotonin Toxicity)  Tapering from Oct 2015 - 13 Nov 2021   LAST DOSE 0.0025mg

My full tapering program     My Intro (goes to my tapering graph)    My website

PLEASE NOTE:  I am not a medical professional.  I provide information and make suggestions. 

Please DO NOT TAG me - thank you.

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Thank you I will try that 

On Prozac 20 mg from 1996 to 2012 started for post partum depression ? Pooped out

2012 - Switched to 1.25 mg Klonopin ( tapered off last dose march 6 th / 2017 ( 14 month taper) 

2012-15 mg lexapro came off nov.4 th /17 

2012- 150 mg Wellbutrin xl ( still on ) 
2019- Stabilized to be functional after coming off lex and klon waiting to get healthy to taper Wellbutrin

2021 Dec - Suprax and macrobid for UTI

2022 Jan - withdrawal symptoms came back with a vengeance ( antibiotics and uti only change ) 

2022 June - still in full withdrawal 

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  • 2 weeks later...

Need Help Tapering Wellbutrin SR

 

I've been trying to read through the posts on tapering Wellbutrin, but I'm still confused. I take 200 mg SR twice per day. Can I cut these or make into a liquid?

 

Thank you.

 

Edited by ChessieCat
added topic title before merging with intro topic

2015 Lexapro 10 mg

2020 Lexapro 20 mg, Wellbutrin 400 mg, Abilify 2 mg, Modafinil 200 mg¬†‚ėĻÔłŹ

3/10/22 - begin 10% taper off Abilify 2 mg.

June 2022 - off Abilify

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@LeoTheLion

 

Wellbutrin SR cannot be dissolved. It is NOT possible to make a liquid of them. This also accounts for Wellbutrin XR. 

 

The only form of Wellbutrin that can be used to make a liquid is the IR (instant release) version.

 

But you can cut the SR. They become IR (instant release) then (only) in effect (still not dissolvable however). Since the become instant release effectively, you should not take a higher dose than 75mg of the cut pill at a time. Otherwise you get a peak in the dosage, which is not fun to experience....

 

I understand you take 200 mg SR daily. I would suggest you would start your tapering by taking 1 full 200mg pill in the morning. And by cutting of 10% of your total daily dose (10% of 400 mg + 40mg cut) of the second pill. Which would be 20% cut on 1 pill daily (and leaving the other 200 mg uncut)

 

So you would cut down the second 200mg pill to 160mg.  You could cut this 160 mg then in 2 or even better 3 equal parts and divide them over the afternoon en early evening. So you spread the IR effect.

 

You would best use scales that can weigh up to 1 mg. You need to weigh the total pill weight first. The pill weight of a 200 mg pill will be more than 200 mg because of filling and coating materials. 

 

If (FOR EXAMPLE) a 200mg SR pill would weigh 300mg, you would have to cut of 20% of the TOTAL pill weight (20% of 300 is 60mg), which would result in a Total pill weight of 300 -/- 60= 240 mg.

 

To be safe I would cut the remaining 240 mg pill weight then in 3 equal pieces (using the scales) and divide them over the 2nd part of the day.

 

Here is more info to be found:

 

 

Edited by Go2zero

1993    Anafranil (Clomipramine) for a few months. Later in 1993 Paxil for a few months 1993- 2006      No medication

2006   Effexor, Cymbalta, some Benzo’s. All for short periods. Later in 2006 Lexapro (escitalopram) 10 mg and shortly after Wellbutrin XR 150mg, against side effects Lexapro 

Since 2006 until end of 2015: Several times on and off Lexapro and Wellbutrin and several slight dosage changes. Mostly taken dosages: 5mg Lexapro and 150mg Wellbutrin

2016  Dosage change Lexapro from 5mg to 2,5 mg. Wellbutrin stayed om 150mg

November 2016 ‚Äď April 2017¬†Down from 2,5mg to 0,6mg Lexapro (in steps) without much problems. Wellbutrin down from 150mg to 66mg. Also without much problems.

April 2017 ‚Äď March 2019¬†¬†¬†¬†¬†¬†¬†Lexapro 0,6 mg ¬† ¬† ¬† ¬†April 2017 - August 2018¬†¬†¬†¬†¬†¬†¬†Wellbutrin in small steps down from 66mg in to 37,5 mg . Quite heavy WD after each step.

March 2019 ‚Äď May 2019¬†Lexapro down from 0,6 to 0,3mg then Prozac to 0,6 mg switch because severe discontinuation effects (may also have been from Wellbutrin..)¬†¬†¬†¬†

Wellbutrin down from 37,5mg to 35,3mg 

October 2019        Seroquel 12,5 mg for 4 weeks because of extreme sleeping problems, then weaning off in 2 weeks       Prozac up dosage to 1,2 mg

March 2020     Wellbutrin in 2 steps down from 35,3mg to 33,3mg   Extreme withdrawal affects during 8 months. Stopped tapering Wellbutrin  until total off Prozac. 

February 2020 ‚Äď November 2020¬†¬†¬†Prozac down in steps from¬†1,2mg to 0,57mg.¬†

Jan 2021 :  Prozac down to:  0,55> 0,53>0,51mg,   Feb 0,47mg ,  Mar 0,42mg,   Apr 0,37, longer hold because of WD symptoms July 0,36 and hold again, Sept 19 0,35, Sept 26 0,34mg, Oct 3 0,33mg  

January 20, 2022:  Wellbutrin from 33,3 to 32,3mg

March 22, 2022 Prozac down from 0,33mg to: 0,30mg, Apr 0,29, May 0,28, 0,27, June 0,26, 0,25

 

Supplements: Fish Oil (3000mg), Magnesium 100 mg, 2 drops of Lavender Oil when feeling anxiety. 50mg of L-Theanine when severe discontinuation effects caused by Wellbutrin

 

Please note this is NOT a medical advice. Discuss all your medical issues with a doctor who understands psychical drugs and really knows how to withdraw from them. I wish that you will find one.

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Thank you very much for the information. I will try this .

2015 Lexapro 10 mg

2020 Lexapro 20 mg, Wellbutrin 400 mg, Abilify 2 mg, Modafinil 200 mg¬†‚ėĻÔłŹ

3/10/22 - begin 10% taper off Abilify 2 mg.

June 2022 - off Abilify

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