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Sybilgirlus: Long time antidepressant user


Sybilgirlus

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Hi!  I am a 47 y.o female who has been on antidepressants and anti anxiety medications since 1990, except during my two pregnancies in 1992 and 1995.  For about the last 15 years, I have been on Paxil 60 mg, Wellbutrin 400 mg, Buspar 60 mg and Klonapin .125-.50 (since 2004.)  Recently, I felt as if the Paxil was no longer doing anything and possibly even making me more anxious and depressed.  I started a slow taper in November, 2014.  I have been Paxil free since March 22, 2015.  The withdrawal was manageable until I hit the 3 week point.  I have been very ill since then with nearly every possible side effect.  Kept taking the other meds as prescribed, but every time I took the Wellbutrin dose, I seemed to become even more dizzy/nauseous/anxious.  Two days ago, I decreased the Wellbutrin SR to 300 mg (150 mg/twice a day to see how this would affect the nausea.  The dizziness and nausea seem a bit better, but now the anxiety is nearly unbearable.  I don't know where to go from here.  My psychiatrist is not very helpful because he mostly just writes prescriptions and talks about himself.  But he is the only local psychiatrist that my insurance will pay for.  My therapist is great, but she would like to see me come totally off the Wellbutrin as well as the Paxil.  So, I have pretty much been doing this by myself.  I'm at the point where I don't know what medicine or lack of medicine is causing which symptoms. Can anyone help me?  Has anyone else been in this antidepressant/antianxiety cocktail nightmare?? 

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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  • Moderator Emeritus

Hi Sybilgirlus , welcome to the site.

 

You're probably right that the Paxil stopped helping , but I'm afraid your "slow" taper of 60mg between Nov.2014 and March 2015

was actually very fast.

This site recommends decreasing by no more than 10% every 3 to 4 weeks. It sounds like you're experiencing protracted withdrawal

syndrome since you stopped.  "Dizzy , nauseous , anxious"  are all  part of the w/d package.

 

The only way to stop this process is by reinstating a small dose of Paxil.  

Try reading "Reinstating to Stop Withdrawal Symptoms" , in the Tapering section.

The idea is that you halt the w/d process , let yourself get stable , then begin to taper s-l-o-w-l-y.

 

Decreasing your Wellbutrin by 25% further complicates the situation.  As it's only been 2 days , I'd be inclined to go back to your

previous dose until your w/d symptoms settle.

 

Try reading some threads in the Tapering section that will help you to understand why you're feeling so terrible.

It's only been one month since you last took paxil , so hopefully a small reinstatement will keep you out of the woods.

 

Good to have you on board ,  Fresh

1987-1997 pertofran , prothiaden , Prozac 1997-2002 Zoloft 2002-2004 effexor 2004-2010 Lexapro 40mg

2010-2012Cymbalta 120mg

Sept. 2012 -decreased 90mg in 6months. Care taken over by Dr Lucire in March 2013 , decreased last 30mg at 2mg per week over 3 months. July 21 , 2013- last dose of Cymbalta

Protracted withdrawal syndrome kicked in badly Jan.2014 Unrelenting akathisia until May 2014. Voluntary hosp. admission. Cocktail of Seroquel, Ativan and mirtazapine and I was well enough to go home after 14 days. Stopped all hosp. meds in next few months.

July 2014 felt v.depressed - couldn't stop crying. Started pristiq 50mg. Felt improvement within days and continued to improve, so stayed on 50mg for 8 months.

Began taper 28 Feb. 2015. Pristiq 50mg down to 45mg. Had one month of w/d symptoms. Started CES therapy in March. No w/d symptoms down to 30mg.

October 2015 , taking 25mg Pristiq. Capsules compounded with slow-release additive.

March 2016 , 21mg

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Thanks for your response, Fresh!  Because I had not yet found this site, I was like you in the matter that I didn't know the correct meaning of slow when it came to tapering off  antidepressants.  It seemed slow to me at the time.  Since I am five just about five weeks out from being Paxil free, I really don't want to reinstate at this point.  I had seemed to be slightly improving until I started the Wellbutrin SR taper.  I believe that I will take your advice about waiting to decrease  the Wellbutrin.  I really only began that taper because my therapist was very concerned about it causing anxiety and wanted me to come off it.  Do you have any idea why my WD symptoms get worse every time I take a Wellbutrin dose?  I was a little worried that the Paxil being out of my system had caused some sort of Wellbutrin overdose.  Thanks for your help!

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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Hey, Fresh!  Since my last post, I have read Maplegirl's experience.  She had to go back on Paxil at 11 months off.  Do you think that is where I will be headed if I do not reinstate a small amount of Paxil now? 

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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  • Moderator Emeritus

Found your thread. I responded to your PM, but I'll write more here.

 

Reinstating can be tricky and some have found it not to be helpful, while others, myself included, have done it with success. Still others have found its made symptoms worse. The complication, as I wrote in the private message, is that Wellbutrin is known to cause an increase in plasma concentration of the SSRI it is taken with. In other words, it's like it makes it more potent. I think I explain it better in the response to your private message.

 

Here's the thread about reinstating: http://survivingantidepressants.org/index.php?/topic/7562-about-reinstating-and-stabilizing-to-stop-withdrawal-symptoms/

 

Read that, and if you have more questions, ask them here.

 

Also, I have found relief from anxiety with Magnesium supplements and several people here seem to be having some success with high doses of vitamin C. Those may be options for you as well.

1988-2012: Prozac @ 60mg to treat an eating disorder. Several unsuccessful attempts to discontinue.Fall 2012: Failed attempt to discontinue then -> 40mg Prozac and added 150mg Wellbutrin. Late summer 2013:Began slower Prozac taper.Spring 2014:Got to 10mg Prozac, 75mg of Wellbutrin -April 2014: 9mg Prozac & 37.5mg Wellbutrin 2x/day -> 9mg Prozac & 25 mg Wellbutrin 2x/day->9mg Prozac 1x/day & ~8mg Wellbutrin 2x/day -> 8.1mg Prozac, 0 WellbutrinSept '14: 8.1mg Prozac -> crashed hardOct '14: 10mg ProzacNov '14: 20mg -> 30mgDec '14: 30mg, Feb 10: 27mg. Mar 7: 25mg Mar 21, 2015: 20mg. May 21, 2016: 20mg and holding strong. Taper restarted April 2021 to 18mg, July 2021 to 16mg, currently 15mg. 

 

My experience: http://rxisk.org/antidepressant-withdrawal-a-prozac-story/

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  • Administrator

Welcome, sybilgirlus.

 

It does sound like going off Paxil put your nervous system in a sensitized state. As far as reinstating, even 1mg might help reduce the withdrawal symptoms from that.

 

Because your nervous system was sensitized by Paxil withdrawal, it sounds like you started to have adverse effects from Wellbutrin. Then, reducing Wellbutrin that much added to the destabilization.

 

If I were you, I'd go up a little on the Wellbutrin, too, maybe to 350mg to reduce the Wellbutrin withdrawal factor. Since you have Wellbutrin on hand, I'd make this correction right away. For titrating Wellbutrin, see Tips for tapering off Wellbutrin, IR, SR, XR, XL (bupropion)

 

Paxil comes in a liquid form for titration, see Tips for tapering off Paxil (paroxetine)

 

I would stay on a very low dose of Paxil while tapering Wellbutrin, as Wellbutrin tends to be activating, see Taking multiple psych drugs? Which drug to taper first?

 

The dosages of all your drugs are quite high. I would want to see how they interact. Please put ALL the drugs you take in the Drug Interactions Checker http://www.drugs.com/drug_interactions.html and post the results in this topic.
 

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Thank you so much, Alto!  I'm having a hard time hanging in there today.  Panic and tears all over the place.  :-(  Thank you for the links.  I have read them and will continue to use them as guides.  I'm going to the Drug Interactions Checker now. 

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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Well, I did the interaction checker.  Results aren't too good.  Two major risk interactions: 

interaction-3-big.png buspirone ↔ paroxetine

Applies to: BuSpar (buspirone), paroxetine

Using busPIRone together with PARoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or shaking, blurred vision, muscle spasm or stiffness, tremor, incoordination, stomach cramp, nausea, vomiting, and diarrhea. Severe cases may result in coma and even death. You should seek immediate medical attention if you experience these symptoms while taking the medications. Talk to your doctor if you have any questions or concerns. Your doctor may already be aware of the risks, but has determined that this is the best course of treatment for you and has taken appropriate precautions and is monitoring you closely for any potential complications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

interaction-3-big.png bupropion ↔ paroxetine

Applies to: bupropion, paroxetine

Talk to your doctor before using buPROPion together with PARoxetine. Combining these medications may increase the risk of seizures, which may occur rarely with either medication. In addition, buPROPion can increase the blood levels of PARoxetine, which may increase other side effects. You may be more likely to experience seizures with these medications if you are elderly, undergoing alcohol or drug withdrawal, have a history of seizures, or have a condition affecting the central nervous system such as a brain tumor or head trauma. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should avoid or limit the use of alcohol during treatment. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

 

 

As well as 10 moderate risk interactions between all the various other medications.   Most of the interactions have to do with seizures and blood pressure changes.   I have only had issues with seizures a couple times:  once when I took too much cough syrup and once when I was given Demerol for wisdom tooth extraction.  I guess that I can be very thankful that there haven't been more times after reading the above. 

 

But what kind of care have I been under???  I feel hopeless and sick and stuck.  I will try Alto's suggestions and see how it goes.  What doesn't kill you makes you stronger?????

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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  • Administrator

Looks like your doctor is drug-happy.

 

A little bit of paroxetine is not going to have the risks of those larger doses you've been taking.

 

Why was the Buspar added?

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Buspar was always prescribed along with the Wellbutrin SR.  I think it was to counteract some of the Wellbutrin side effects of anxiety.  I am a military dependent.  All this care has been under military doctors and their contractors. 

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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  • Administrator

If the Wellbutrin was making you anxious, that's not a good effect on your nervous system.
 
Do you have any Paxil left? If you do, I might try 1mg Paxil rather than adding to the Wellbutrin.

Use the liquid form of Paxil to take 1mg, you can make your own liquid, see Tips for tapering off Paxil (paroxetine)

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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I do still have Paxil left; 20 mg tabs.  I was thinking about cutting a tablet in half and then half again and taking 5 mg along with increasing the Wellbutrin up to 350 mg.  I was thinking that maybe I could stabilize on that and then eventually taper the Wellbutrin before going back down on and then off the Paxil.  I still take the Buspar and Klonapin as well, so actually decreasing the Wellbutrin has made me WAY more anxious than I ever felt while taking it.  Alto, what do you think of this plan?  Do you think the 5 mg Paxil is too much?  Am I reinstating or just trying to lower the nervous system sensitivity? Thanks for your continued help!

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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Bad night. Bad morning. I took the 5 mg of Paxil last night. The first two hours, I could feel my body relaxing. I couldn't sleep, but at least the constant panic was waning. Then, slowly over the next couple hours a terrible rage built up inside me. If I hadn't been home in bed with my husband, I think that I or someone else could have been in grave danger. I finally got up and took some melatonin and fell asleep within the next hour. I woke up very angry and nauseous. Upon smelling food, I began dry heaving. Blech! So, I got up, took my full morning wellbutrin and buspar dosages and have been lying in bed waiting to feel better since then. Alto, I think you were right about not needing much paxil. Does it sound to you like too much of that was the problem?

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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  • Administrator

You may note I suggested 1mg Paxil.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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Yes, I did note that. Thanks. Sorry to have strayed from your advice. I was just confused at bedtime last night and wasn't sure if my objective was to reinstate or just counteract the Wellbutrin.

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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  • Administrator

No problem. You might try 1mg tonight.

 

If it works, a little Paxil might reduce your withdrawal symptoms overall.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

Link to comment

Found your thread. I responded to your PM, but I'll write more here.

 

Reinstating can be tricky and some have found it not to be helpful, while others, myself included, have done it with success. Still others have found its made symptoms worse. The complication, as I wrote in the private message, is that Wellbutrin is known to cause an increase in plasma concentration of the SSRI it is taken with. In other words, it's like it makes it more potent. I think I explain it better in the response to your private message.

 

Here's the thread about reinstating: http://survivingantidepressants.org/index.php?/topic/7562-about-reinstating-and-stabilizing-to-stop-withdrawal-symptoms/

 

Read that, and if you have more questions, ask them here.

 

Also, I have found relief from anxiety with Magnesium supplements and several people here seem to be having some success with high doses of vitamin C. Those may be options for you as well.

Thanks for your response, Addax.  Sorry I didn't reply earlier.  Feeling pretty crappy.

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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Can anyone please tell me that if reinstating works, will this crippling panic and anxiety go away?  Sometimes I don't know if I can make it through another day.

Started antidepressants and anti-anxiety meds in 1990 after complete mental breakdown; don't remember exactly what.

Most recent med combo was Paxil, Wellbutrin and Buspar started sometime between 1995 and 2000. 

Continued on these meds with the addition of Klonapin in 2004.  Maxed out all doses except Klonapin.

Due to Paxil poop-out, started a slow taper in November 2014. 

Paxil free since March 22, 2015.  Major withdrawal symptoms with a large spike at 4 weeks Paxil free. 

Started taper of Wellbutrin 2 days ago.  Severe anxiety.

Current dosages:  Wellbutrin SR 300 mg (down from 400 mg,) Buspar 60 mg/day and Klonapin .12-.5 mg/night

Also currently taking Lotrel for high blood pressure related to kidney disease, Synthroid .075 mg and Aspirin 82 mg

 

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  • Moderator Emeritus

I know it is possible. I've CT'd a few times now and always recovered after about a month of going back on. Just wish I'd known the difference between relapse and withdrawal, and been told about slow tapering.

2001: 20mg paroxetine
2003-2014: Switched between 20mg citalopram and 10mg escitalopram with several failed CT's
2015: Jan/ Feb-very fast taper off citalopram; Mar/ Apr-crashed; 23 Apr-reinstated 5mg; 05 May-updosed to 10mg; 15 Jul-started taper; Aug-9.0mg; Sep-8.1mg; Oct-7.6mg; Nov-6.8mg; Dec-6.2mg
2016: Jan-5.7mg; Feb-5.2mg; Mar-5.0mg;  Apr-4.5mg; May-4.05mg; Jun-3.65mg; Jul-3.3mg; Aug-2.95mg; 04Sep-2.65mg; 25Sep-2.4mg; 23Oct-2.15mg; 13Nov-1.95mg; 04Dec-1.75mg; 25Dec-1.55mg.
2017: 08Jan-1.4mg; 22Jan-1.25mg; 12Feb-1.1mg; 26Feb-1.0mg; 05Mar-0.9mg; 15Mar-0.8mg; 22Mar-0.7mg; 02Apr-0.6; 09Apr-0.5mg; 16Apr-0.4mg; 23Apr-0.3; 03May-0.2mg; 10May-0.1mg

Finished taper 17 May 2017.

 

I am not a medical professional. The information I provide is not medical advice. If in doubt please consult with a qualified healthcare provider.

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  • Administrator

We wouldn't suggest it if it didn't help people at least sometimes.

This is not medical advice. Discuss any decisions about your medical care with a knowledgeable medical practitioner.

"It has become appallingly obvious that our technology has surpassed our humanity." -- Albert Einstein

All postings © copyrighted.

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  • 2 weeks later...
  • Moderator Emeritus

How are you doing sybilgirlus?

1987-1997 pertofran , prothiaden , Prozac 1997-2002 Zoloft 2002-2004 effexor 2004-2010 Lexapro 40mg

2010-2012Cymbalta 120mg

Sept. 2012 -decreased 90mg in 6months. Care taken over by Dr Lucire in March 2013 , decreased last 30mg at 2mg per week over 3 months. July 21 , 2013- last dose of Cymbalta

Protracted withdrawal syndrome kicked in badly Jan.2014 Unrelenting akathisia until May 2014. Voluntary hosp. admission. Cocktail of Seroquel, Ativan and mirtazapine and I was well enough to go home after 14 days. Stopped all hosp. meds in next few months.

July 2014 felt v.depressed - couldn't stop crying. Started pristiq 50mg. Felt improvement within days and continued to improve, so stayed on 50mg for 8 months.

Began taper 28 Feb. 2015. Pristiq 50mg down to 45mg. Had one month of w/d symptoms. Started CES therapy in March. No w/d symptoms down to 30mg.

October 2015 , taking 25mg Pristiq. Capsules compounded with slow-release additive.

March 2016 , 21mg

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