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Link found between brain, immune system: significant for those with protracted psych drug withdrawal issues


GiaK
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from Beyond Meds  http://wp.me/p5nnb-cnc
 

This link is important to know about for many chronic conditions.
 

I have lived experience of this reality. I know it.
 

Immune system and nervous system are totally linked…I can feel it.
 

Folks in the chronic illness circles are all saying the same thing as well…we feel it…and those of us with protracted psychiatric drug withdrawal issues are also impacted…This is not news to us. Still, it’s important information for the scientific and medical communities.
 

From University of Virginia Medical School. A press release:
 

In a stunning discovery that overturns decades of textbook teaching, researchers at the School of Medicine have determined that the brain is directly connected to the immune system by vessels previously thought not to exist. That such vessels could have escaped detection when the lymphatic system has been so thoroughly mapped throughout the body is surprising on its own, but the true significance of the discovery lies in the effects it could have on the study and treatment of neurological diseases ranging from autism to Alzheimer’s disease to multiple sclerosis.  (
)

 

 


Those of us with protracted withdrawal issues quite often have the sorts of neurological issues that this research is talking about.
 

The two pieces below also speak to some of these issues though I don’t make all the connections explicitly. I share this sort of information for those who can do make the connections for themselves and then do further research.
 


More on Psychiatric Drug Withdrawal and Chronic Illness on Beyond Meds.

 

from Beyond Meds  http://wp.me/p5nnb-cnc

Everything Matters: Beyond Meds 

https://beyondmeds.com/

withdrawn from a cocktail of 6 psychiatric drugs that included every class of psych drug.
 

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really great stuff.  i had been researching the overarching auto-immune nature of all my long-term medical conditions in life (from the past few decades, not just post-meds) before i started suspecting protracted withdrawal, and this is a neat thing for them to finally be admitting.

 

science is such a joke, especially medical science..."We always perceived it before as something esoteric that can’t be studied"---and we bought their 'scientific' cures year after year!  utter buttquackery.

 

do you have any spiritual musings on the philosophical nature of 'auto-immune' mechanisms being behind a vast amount of human illness?  ive wondered, ever since withdrawal began, if these physical trials are more just the literalization of something far more abstract and, essentially, extra-corporeal.

from 2005-2012, i spent 7 years taking 17 different psychotropic medications covering several classes.  i would be taking 3-7 medications at a time, and 6 out of the 17 medications listed below were maxed or overmaxed in clinical dosage before i moved on to trying the next unhelpful cocktail.
 
antidepressants (SSRIs, SNRIs, NDRIs, tetracyclics): zoloft, wellbutrin, effexor, lexapro, prozac, cymbalta, remeron
antipsychotics (atypical): abilify, zyprexa, risperdal, geodon
sleep aids (benzos, off-label antidepressants & antipsychotics, hypnotics): seroquel, temazepam, trazodone, ambien
anxiolytics: buspar
anticonvulsants: topamax
 
i tapered off all psychotropics from late 2011 through early 2013, one by one.  since quitting, ive been cycling through severe, disabling withdrawal symptoms spanning the gamut of the serious, less serious, and rather worrisome side effects of these assorted medications.  previous cross-tapering and medication or dosage changes had also caused undiagnosed withdrawal symptoms.
 
brainpan addlepation

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the only spiritual nugget I've got for you at the moment is "the physical is the spiritual"  -- there is no separation...the more deeply I contemplate that the more it all makes sense...

Everything Matters: Beyond Meds 

https://beyondmeds.com/

withdrawn from a cocktail of 6 psychiatric drugs that included every class of psych drug.
 

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i can completely agree, and i think my more specific (unspoken) question is difficult to even formulate into words...  i just wonder at the possibilities, and the malleability of our experiences.  the capacity for instantaneous radical change, and the responsibilities and self-directedness we may or may not have if, as you said, there is essentially a singular, though ostensibly infinite, 'reality'.

 

i sometimes feel a dissolution of ego, and i wonder if it is where to go.  i feel the timelessness of everything in all my conscious hours, and sometimes, oftentimes, everything in life makes sense.  but when it comes to completely 'disappearing', i have doubts sometimes.  i dont want to give away all control and sense of specificity or self and then come back into a conscious and personed state with a bloody knife in my hands or some crazy **** like that.  banking on the theory of radical infinitude, anything 'bad' i could "come back to" would still be an ego manifestation and only resolving that internal struggle would change my situation in the 'external' world as well, but i guess that just means i sometimes doubt my efficacy as a living being.

 

i wonder if ego is the method of instruction for attaining that perfect unity and synchronicity with the infinite, so that we can know our progress---and need for progress---through the state of our attachment to it.  perhaps we are always interacting on both the infinite and consciously specific levels, and navigating our focus of experience between the modes of perception is merely about focus instead of the wider reality we are participating in, but sometimes i wonder if i am supposed to be something more.  or, less, as it were...to simply transcend the perceptions of physicality, however transient they already are, and inhabit as does everything else we observe or imagine---the thoughtless being, no self-concept or boundaries, just plain, holistic, un-deferring expression.

 

sorry if that sounds droning or batshit.

from 2005-2012, i spent 7 years taking 17 different psychotropic medications covering several classes.  i would be taking 3-7 medications at a time, and 6 out of the 17 medications listed below were maxed or overmaxed in clinical dosage before i moved on to trying the next unhelpful cocktail.
 
antidepressants (SSRIs, SNRIs, NDRIs, tetracyclics): zoloft, wellbutrin, effexor, lexapro, prozac, cymbalta, remeron
antipsychotics (atypical): abilify, zyprexa, risperdal, geodon
sleep aids (benzos, off-label antidepressants & antipsychotics, hypnotics): seroquel, temazepam, trazodone, ambien
anxiolytics: buspar
anticonvulsants: topamax
 
i tapered off all psychotropics from late 2011 through early 2013, one by one.  since quitting, ive been cycling through severe, disabling withdrawal symptoms spanning the gamut of the serious, less serious, and rather worrisome side effects of these assorted medications.  previous cross-tapering and medication or dosage changes had also caused undiagnosed withdrawal symptoms.
 
brainpan addlepation

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nope not droning or batshit...I think about the same things. 
 

have you read "The End of Your World" by Adyashanti?  I found it helpful because I too have periods of dissolution of ego and he talks about that process in ultimately healing as well.

 

Also...I just thought of another article on Beyond Meds by Charles Eisenstein you might enjoy:

 

Mutiny of the Soul  || Charles Eisenstein http://wp.me/p5nnb-bYg 

Everything Matters: Beyond Meds 

https://beyondmeds.com/

withdrawn from a cocktail of 6 psychiatric drugs that included every class of psych drug.
 

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i havent encountered either of those, and have bookmarked them for readingtime. i was able to scan some of the book reviews...that plus the introductory summary already gives a decent picture. and someone mentioned Ramana Maharshi, so i skimmed a bit on him and can read more sometime.

 

i find communication on the subject difficult because terminology is inherently at odds with purity of experience, and conscious communication is essentially the opposite of fuller being. discussion can usually only meaningfully happen when someone shares a rough framework of definitions to draw on, and i feel like maybe i have enough in common with these writings you mentioned to adequately translate at this point.

 

ive always been fond of taoism, too, which speaks well on the ineffability and unteachable nature of 'the infinite'.

from 2005-2012, i spent 7 years taking 17 different psychotropic medications covering several classes.  i would be taking 3-7 medications at a time, and 6 out of the 17 medications listed below were maxed or overmaxed in clinical dosage before i moved on to trying the next unhelpful cocktail.
 
antidepressants (SSRIs, SNRIs, NDRIs, tetracyclics): zoloft, wellbutrin, effexor, lexapro, prozac, cymbalta, remeron
antipsychotics (atypical): abilify, zyprexa, risperdal, geodon
sleep aids (benzos, off-label antidepressants & antipsychotics, hypnotics): seroquel, temazepam, trazodone, ambien
anxiolytics: buspar
anticonvulsants: topamax
 
i tapered off all psychotropics from late 2011 through early 2013, one by one.  since quitting, ive been cycling through severe, disabling withdrawal symptoms spanning the gamut of the serious, less serious, and rather worrisome side effects of these assorted medications.  previous cross-tapering and medication or dosage changes had also caused undiagnosed withdrawal symptoms.
 
brainpan addlepation

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" inhabit as does everything else we observe or imagine---the thoughtless being, no self-concept or boundaries, just plain, holistic, un-deferring expression."

 

For me this speaks to the reality I want to live in and I also think it to be the state we came in if after a full life we can leave in the same state ... a bit fuller or grown up then life was a success. 

 

Some things I truly believe I would not know if it were not for drugs and I would be quite happy not to know them.  If you were in tune with your spirit self call it what you will before drugs not in a church sort of way but a down to earth living in your body and happy about it way... this may ring true.. that while we are living in our body we always in the spiritual that is how it feels to me.  When the drugs messed with the system things went haywire in all sorts of way reflected in the spiritual sense of self as well.  

 

Getting back to the natural is what I wish for but I fear that sense of ease will never come back.. though I do so long for it. Bit like being robbed is how it feels to me.. not that I am or have any great knowledge about this I don't... I just know myself and miss what I had. 

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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http://newsroom.uvahealth.com/about/news-room/missing-link-found-between-brain-immune-system-with-profound-disease-implications

 

 

What a wonderful find! Thank you for posting it. 

I sure do feel it I wonder how long it will take to figure out if they can fix us... or me and others like me. 

 

Have there been any comments at all from those few docs who believe us about this article i am going to look. :) if I find anything I will post it back here. 

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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Just old stuff..and hints 

http://davidhealy.org/42-or-thereabouts/

Other researchers are testing the immune-inflammatory hypothesis – the idea that depression is caused by inflammation due to an overworked immune system.
Another line of thinking, known as the bio-energetic hypothesis, suggests that tiny powerhouses within brain cells may not be producing or disposing of energy and energy byproducts properly. This may lead to destruction of brain cells, and consequently, depression.

 

For example, severe depression is a side effect of interferon, a drug prescribed to spur the immune system in patients with skin cancer and Hepatitis C. Studies have shown that preventive treatment with SSRIs greatly reduces the risk of depression in patients on interferon. Based on these findings, “clearly the serotonin drugs have indirect effects on the immune-inflammatory system,” McIntyre said.

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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I sure as heck am not waiting for "them" to fix us..."they" fucked us up and while this information is largely validating medicine has a way of using such info to further harm rather than help...

 

there are already people working with systems that intuitively understand this stuff...the really good ones are hard to find but the knowledge is out there in other systems of medicine and intuitive practices of all sorts so it's possible to put together healing protocols for ourselves...a lot of folks in chronic healing circles have done it as well as many of us...some more or less consciously...not everyone realizes what they're doing when they find the way to good health...we really do it in all sorts of different ways

 

the bottom line, too, is that these sorts of conditions impacted by these systems manifest in unique ways in everyone, so we still have to figure ourselves out...MDs willl always be limited in knowing how to meet everyone's needs...again, why we do need to learn to doctor ourselves. 

Everything Matters: Beyond Meds 

https://beyondmeds.com/

withdrawn from a cocktail of 6 psychiatric drugs that included every class of psych drug.
 

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I sure as heck am not waiting for "them" to fix us..."they" fucked us up and while this information is largely validating medicine has a way of using such info to further harm rather than help...

 

there are already people working with systems that intuitively understand this stuff...the really good ones are hard to find but the knowledge is out there in other systems of medicine and intuitive practices of all sorts so it's possible to put together healing protocols for ourselves...a lot of folks in chronic healing circles have done it as well as many of us...some more or less consciously...not everyone realizes what they're doing when they find the way to good health...we really do it in all sorts of different ways

 

the bottom line, too, is that these sorts of conditions impacted by these systems manifest in unique ways in everyone, so we still have to figure ourselves out...MDs willl always be limited in knowing how to meet everyone's needs...again, why we do need to learn to doctor ourselves. 

Thanks for shaking me awake Gia I can't believe I slipped back into the hope of a system I use to believe in... I still want to believe in on some way.  Partly because of some doctors who are fighting the good fight.  If it were not for them perhaps I would have the hope of a ethical system still lurking ready to jump in. The idea that something I do not understand is broken in a profound way ... that does not seem to want to heal itself ... this too keeps me hoping in ethical science.  The slip is human I suppose tho I know it has hurt me so many times in devastating ways. I want to believe even when I can't trust I still want to believe. 

Oddly enough it is like some sort of base need I have to live within a communal system that does not damage it's people for cash... I keep hoping for it. I know there are predators within the circle .. or top down at the top of the circle... still I am not willing to give up on the dream. 

Like a dual reality I live in isolation.. distinctly removed from the larger group I once was part of.. I want back in. At the same time I am not willing to conform my thinking to align with demands I buy in... so to change the system would allow me access so they change and I can be free inside the circle again.  I think this is just a myth I want to believe. A fantasy of sorts. Should the larger circle shift to allow my new reality I would never again trust blindly and given the option of a new pill my sirens would go off again.  I could never trust it again even after a shift as I know too soundly the nature of the beast... I want a new beast.. kill this one and raise my own as I don't believe this one can be taught to play nice. 

 

In order to lean and to heal first there needs to be a baseline of decent health... till then all is lost. I do agree we find ways to heal individually we have to. 

I am sure I have more thinking and seeking ahead. Thanks Gia 

peace

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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I can't help but wonder how this newly discovered system will affect this idea:

“gut-brain axis”

http://chriskresser.com/the-healthy-skeptic-podcast-episode-9/

 

Now one of the earliest signs of the brain not firing well is poor vagal activity, which will manifest as decreased pancreatic enzyme secretion, poor gallbladder function, and poor gut function overall. And it basically works like this, you have decreased activity in the brain, and we’re gonna talk about how that can happen in a second, and that decreases the activation of the vagal motor nuclei, which in turns suppresses the intestinal immune system and decreases intestinal blood flow. And when that happens you get an increased growth in pathogenic yeast and bacteria, that cause intestinal permeability or leaky gut, which we’ve talked about a lot, and leaky gut causes a state of chronic low grade inflammation. Then the inflammatory cytokines produced in the gut travel through the blood and they cross the blood-brain barrier. One of the problems with inflammation is that it makes the blood-brain barrier leaky so you get leaky brain. And then those inflammatory cytokines once they get into the brain activate the microglial cells, which are the second type of cell in the brain. You have neurons and then you have microglial cells. The microglial cells are the immune cells of the brain and once they’re activated by these inflammatory cytokines this is basically inflammation of the brain. So your brain gets inflamed, you get a leaky brain and then you get inflamed brain. And that’s no fun, definitely. Cause one of the problems is that unlike the rest of the immune system in the body that has T-regulatory cells that can turn off inflammation in the brain, the microglial cells don’t get turned off. So, when you’ve got an inflamed brain it can be really tricky to reduce that inflammation without some outside help. So, you’ve got an inflamed brain and the inflammation in the brain decreases nerve conductance and that in turn causes depression and reduced activity of the vagal motor nuclei, and of course then we’re back where we started. That reduced activity of the brain reduces the output into the vagus, and that causes more digestive problems, more inflammation in the gut, more inflammatory cytokines to be in the bloodstream and up into the brain and we’re stuck in this really viscous cycle.

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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  • 6 months later...
A possible participation of transient receptor potential ...
www.researchgate.net/.../224866439_A_possible_participation_of_transien...

Publication » A possible participation of transient receptor potential vanilloid type 1 channels in the antidepressant effect of fluoxetine.

 

Vanilloid ... affects pain and inflammation btw  wd hurts!

WARNING THIS WILL BE LONG
Had a car accident in 85
Codeine was the pain med when I was release from hosp continuous use till 89
Given PROZAC by a specialist to help with nerve pain in my leg 89-90 not sure which year
Was not told a thing about it being a psych med thought it was a pain killer no info about psych side effects I went nuts had hallucinations. As I had a head injury and was diagnosed with a concussion in 85 I was sent to a head injury clinic in 1990 five years after the accident. I don't think they knew I had been on prozac I did not think it a big deal and never did finish the bottle of pills. I had tests of course lots of them. Was put into a pain clinic and given amitriptyline which stopped the withdrawal but had many side effects. But I could sleep something I had not done in a very long time the pain lessened. My mother got cancer in 94 they switched my meds to Zoloft to help deal with this pressure as I was her main care giver she died in 96. I stopped zoloft in 96 had withdrawal was put on paxil went nutty quit it ct put on resperidol quit it ct had withdrawal was put on Effexor... 2years later celexa was added 20mg then increased to 40mg huge personality change went wild. Did too fast taper off Celexa 05 as I felt unwell for a long time prior... quit Effexor 150mg ct 07 found ****** 8 months into withdrawal learned some things was banned from there in 08 have kept learning since. there is really not enough room here to put my history but I have a lot of opinions about a lot of things especially any of the drugs mentioned above.
One thing I would like to add here is this tidbit ALL OPIATES INCREASE SEROTONIN it is not a huge jump to being in chronic pain to being put on an ssri/snri and opiates will affect your antidepressants and your thinking.

As I do not update much I will put my quit date Nov. 17 2007 I quit Effexor cold turkey. 

http://survivingantidepressants.org/index.php?/topic/1096-introducing-myself-btdt/

There is a crack in everything ..That's how the light gets in :)

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